Prokinetics: ib daim ntawv teev cov tshiab tiam ntawm cov tshuaj

Tam sim no, ib qho kev ua ntawm mus ntsib kws kho mob - cov no yog cov teeb meem nyob rau hauv txoj hnyuv ib ntsuj av. Yuav luag txhua yam ntawm lawv yus los ntawm ib tug ua txhaum ntawm lub cev muaj zog muaj nuj nqi. Txawm li cas los, tej zaum lawv yuav tshwm sim raws li cov tsos mob ntawm ib qho kev mob uas yog tsis txuam nrog lub digestive system. Nyob rau hauv txhua rooj plaub, tsis tau tsis muaj tshuaj pab pawg neeg prokinetics. Daim ntawv teev cov tshuaj nyob rau hauv pab pawg neeg no tsis yog muaj kev txwv lub moj khaum. Yog li ntawd, txhua txhua tus kws kho mob xaiv lawv kev npaj, nyob ntawm seb tus kab mob. Tom ntej no, siv sij hawm ib tug los ze zog saib, yog dab tsi prokinetics, daim ntawv teev cov tshiab-tiam khoom, feem ntau siv rau kev kho mob.

Prokinetics: general yam ntxwv

Cov tshuaj uas hloov lub cev muaj zog ua si ntawm lub plab hnyuv ib ntsuj av tau thiab leeb zaub mov transit thiab muab nchuav txheej txheem, cia li mus rau qhov no pab pawg neeg.

Raws li hais saum toj no, ib tug tib daim ntawv teev cov tshuaj nyob rau hauv Gastroenterology ntaub ntawv tsis muaj nyob. Txhua tus kws kho mob no muaj xws li ib daim ntawv teev cov tshuaj. Cov no muaj xws tshuaj, thiab lwm yam pab pawg, xws li antiemetics, antidiarrheals, thiab ib co macrolide tshuaj tua kab mob, hormonal peptides. Yuav pib paub dab tsi yog qhov pharmacological kev txiav txim ntawm pab pawg neeg no ntawm cov tshuaj.

txiav txim prokinetic

Ua ntej ntawm tag nrho lawv yuav txhim khu lub kom ntawm cov hnyuv, raws li zoo raws li muaj antiemetic nyhuv. Tej npaj leeb lub muab nchuav ntawm lub plab thiab cov hnyuv, ua kom cov nqaij leeg laus cov hnyuv, inhibit qhov kev pyloric thiab oesophageal reflux. Prokinetics muab raws li monotherapy los yog nyob rau hauv ua ke nrog nrog lwm yam tshuaj. Lawv yuav tsum tau muab faib ua ob peb hom raws li lub hauv paus ntsiab lus ntawm kev txiav txim.

hom prokinetic

Lub hauv paus ntsiab lus ntawm cov lag luam rau txawv feem ntawm tus mob huam yog txawv los ntawm cov tshuaj xws li prokinetics. Daim ntawv teev cov tshuaj yuav tsum tau muab faib mus rau hauv lub nram qab no:

1. blockers ntawm dopamine receptors:

• Selective 1st thiab 2nd tiam.
• Nonselective.

2. Cov antagonists ntawm 5-HT3 receptors.

3. agonists ntawm 5-HT3 receptors.

Thiab tam sim no nyob rau hauv ntau yam txog cov pab pawg.

Dopamine receptor blockers

Tshuaj nyob rau hauv pab pawg neeg no raug muab faib ua xim thiab uas tsis yog-xim. Lawv cov nyhuv yog hais tias lawv tsim kho lub cev muaj zog muaj nuj nqi ntawm lub plab thiab muaj antiemetic zog. Yuav ua li cas yog prokinetic? daim ntawv teev cov tshuaj yog raws li nram no:

• "Metoclopramide".
• "Bromopride".
• "Domperidone".
• "Dimetpramid".

Lub ntsiab active ingredient - metoclopramide, siv nws rau ib ntev lub sij hawm. Qhov kev txiav txim yog raws li nram no:

• Nce kev ua si ntawm lub sab esophageal sphincter.
• Acceleration ntawm pais plab muab nchuav.
• Qhov nce nyob rau hauv tus nqi ntawm lub zog ntawm cov zaub mov los ntawm cov hnyuv thiab cov nyuv.

Txawm li cas los, uas tsis yog-xim tshuaj yuav ua rau muaj mob loj heev tshwm sim.

Muaj yog ib tug zoo-paub thawj tiam ntawm prokinetics. Daim ntawv teev cov tshuaj:

• "Reglan".

• "Raglan".
• "Perinorm".
• "Tseruglan".

Ib tug ntawm cov drawbacks yog lub peev xwm yuav ua tau kom tej yam tshwm sim thiab cov tsos mob ntawm Parkinson tus kab mob nyob rau hauv cov neeg laus thiab nyob rau hauv cov me nyuam dyskinetic syndrome, coj khaub mob nyob rau hauv cov poj niam.

By xim thib ob-tiam tshuaj yog cov tshuaj muaj tus nquag tshuaj domperidone. Cov tshuaj tsis ua mob loj heev phiv tshuaj, tab sis tej zaum yuav tshwm sim ntau tshaj:

• Nkees nkees.
• Tsis muaj zog.
• Ntxhov siab vim.
• Mob taub hau.

Nws yog vim li no cov tshuaj muaj tus nquag tshuaj domperidone - qhov zoo tshaj plaws prokinetics. Daim ntawv teev cov tshuaj:

1. "Motilium".
2. "Domidon".
3. "Motinorm".
4. "Motoriks".
5. "Gastropom".

Ib tug tshiab tiam ntawm prokinetics

By xim thib ob tiam ntawm prokinetic agents xws li cov active tshuaj itopride hydrochloride. Tej nyiaj tau paub ua tsaug rau lub zoo heev kho nyhuv thiab lub tsis tuaj kawm ntawv ntawm cov kev phiv, txawm nrog heev siv. Feem ntau cov feem ntau, cov kws kho mob muab tshuaj rau:

• "Itomed".
• "Ganatom".
• "Itopride."

Qhov no yuav ua tau piav los ntawm lub zoo zog itopride hydrochloride:

1. Improvement ntawm lub cev muaj zog thiab kev khiav tawm muaj nuj nqi ntawm lub plab.
2. Nce kev ua si ntawm lub tsib lub zais zis.
3. Ua kom agility thiab suab nrov ntawm lub me me thiab hnyuv loj nqaij.
4. Txhawb cov tshem tawm ntawm duodenal reflux.

hnyuv prokinetics

Cov no muaj xws prokinetics - agonists ntawm 5-HT3 receptors. Lub active tshuaj - tegaserod. Nws muaj ib tug zoo ntxim rau lub cev muaj zog thiab kev khiav tawm muaj nuj nqi ntawm cov nyuv thiab hnyuv. Nws muaj txhawb rau normalization ntawm lub rooj zaum, thiaj li tsos mob ntawm tus chim siab plob tsis so tswj.

Nws tsis ua rau ib qho kev nce nyob rau hauv siab twb tsis muaj ntxim rau cov hlab plawv system. Txawm li cas los, muaj ib tug txaus tus naj npawb ntawm cov kev phiv. Thaum ob peb lub sij hawm tsub kom qhov uas yuav mob stroke, angina pectoris, ntawm anginal nres. Tam sim no, cov tshuaj muaj tus nquag tshuaj tshem tawm los ntawm cov nyob rau hauv peb lub teb chaws thiab nyob rau hauv lwm lub teb chaws ntxiv cov kev tshawb fawb. Qhov no muaj xws li cov nram qab no prokinetics (tshuaj daim ntawv teev):

• "Tegaserod."
• "Zelmak".
• "Fractal".

Antagonists 5-NTZ receptors

Prokinetics no pab pawg neeg haum rau cov kev kho mob thiab kev tiv thaiv kev xeev siab thiab ntuav. Thaum lawv txais tos txo qhov chaw nyob lub sij hawm ntawm cov zaub mov nyob rau hauv lub plab, muaj zog zaub mov transit ceev los ntawm cov hnyuv, normalizes lub suab nrov ntawm cov nyuv.

Muaj acetylcholine tso tawm, thiab paub lub cev muaj zog muaj nuj nqi ntawm txoj hnyuv ib ntsuj av. Tam sim no nyob rau hauv zoo kawg thov cov neeg mob thiab cov kws kho mob hnub no prokinetics. Daim ntawv teev cov tshiab tiam tshuaj:

• "Tropisetron."
• "Osetron".
• "Ondansetron".
• "Silansetron".

Nws yuav tsum tau muab sau tseg tias antagonists ntawm 5-NTZ receptors tsis muaj ib tug kho nyhuv, yog tias ntuav tshwm sim los ntawm apomorphine.

Cov tshuaj no zoo taus, txawm hais tias muaj muaj kev phiv:

• Mob taub hau.
• Cem quav.
• Flushing.
• Kub flashes.

Lwm ntxiv ntawm cov tshuaj - lawv tsis muaj ib tug sedative nyhuv, tsis txhob koom tau nrog lwm cov tshuaj tsis ua endocrine kev hloov uas tsis ua txhaum lub cev muaj zog ua si.

Uas kab mob taw

Raws li tau piav saum toj no, prokinetics siv nyob rau hauv monotherapy los yog nyob rau hauv nrog tshuaj tua kab mob. Cov kws kho mob paub hais tias muaj cov kab mob nyob rau hauv uas lub sij hawm ntawm prokinetic ob peb lub sij hawm tsub kom cov hauj lwm zoo ntawm kev kho mob. Nyob rau hauv pab pawg neeg no yog:

1. Kab mob ntawm cov digestive system nrog impaired lub cev muaj zog ua si.
2. Gastroezofagelnuyu reflux tus kab mob.
3. Mob plab rwj (duodenal rwj).
4. Idiopathic gastroparesis.
5. Ntuav.
6. Cem quav.
7. Chim siab plob tsis so tswj Syndrome.
8. Ntshav qab zib gastroparesis.
9. Flatulence.
10. Xeev siab tshwm sim los ntawm cov tshuaj thiab tawg txoj kev kho, tus kab mob, kev haumxeeb mob, noj tsis txaus.
11. Dyspepsia.
12. Biliary dyskinesia.

Leej twg yuav tsum tsis txhob coj

Rau kev npaj ntawm prokinetics muaj contra-indications:

• Npau taws me ntsis rau lub active tshuaj.
• Mob plab los yog plab hnyuv los ntshav.
• Perforation ntawm lub plab los sis hnyuv.
• Ileus.
• Mob siab ua hauj lwm, mob raum mob.

Tsis pom zoo txais tos, yog hais tias tus ua hauj lwm yuav tsum tau ntau dua kom pom tseeb thiab concentration, raws li zoo raws li cov neeg uas lub ntsiab ib lub tsheb. Nrog kev saib xyuas muab prokinetics neeg laus.

Cev Xeeb Tub thiab niam

Ob peb lo lus kuv xav hais tias hais txog kev noj tshuaj thaum lub sij hawm cev xeeb tub. Kev tshawb fawb tau qhia tias prokinetics muaj ib tug ib txwm mus txeem mus rau hauv niam cov kua mis, li ntawd, lub sij hawm ntawm kev kho mob nrog rau cov tshuaj yuav tsum tsis txhob mus ntxiv pub niam mis.

Nyob rau hauv thawj peb lub hlis uas cev xeeb tub rau cov poj niam feem ntau yog ntuav thiab xeev siab. Nyob rau hauv cov ntaub ntawv no, koj yuav tau muab cov tshuaj no raws li prokinetics. Daim ntawv teev cov khoom uas siv rau cev xeeb tub cov poj niam Nws yuav muaj xws li tsuas yog cov uas tsis txhob ua rau ib tug kev hem thawj rau lub neej ntawm lub cev xeeb tub poj niam thiab tus me nyuam hauv plab.

Cov kev pab ntawm nws yog ntau tshaj tag nrho cov tau txaus ntshai. Prokinetics metoklopromid muaj tus nquag tus neeg saib xyuas tej zaum yuav siv los ntawm pab pawg neeg no tsuas yog nyob rau cov tshuaj. Nyob rau hauv tom qab trimesters ntawm cev xeeb tub prokinetiki tsis taw.

Tam sim no, qhov no pab pawg neeg ntawm cov tshuaj thaum lub sij hawm cev xeeb tub yog tsis qhia vim hais tias ntawm lub loj tus naj npawb ntawm kev phiv.

Prokinetics rau cov me nyuam

Prokinetics thov mus rau lub active ingredient metoclopramide nyob rau hauv cov me nyuam yuav tsum sobenno ceev faj, raws li muaj ib tug uas yuav ntawm tshwm sim ntawm dyskinetic syndrome. Nws yog tshuaj nyob ntawm seb tus me nyuam hnyav.

Yog hais tias ib tug hoomaum taw prokinetics, "Motilium" yog feem ntau muaj nyob rau hauv daim ntawv teev. Nws yog zoo taus thiab muaj ib tug ntau ntawm cov zoo tswv yim. Tab sis yuav tau muab lwm yam prokinetics. Daim ntawv teev cov tshuaj rau cov me nyuam yuav muaj raws li nram no npe tsis tau:

• "Domperidone".
• "Metoklopromid".

Nws yog ib nqi sau cia hais tias cov me nyuam nyob rau hauv 5 lub xyoos ntawm kev npaj "Motilium" pom zoo rau siv nyob rau hauv daim ntawv ntawm ib ncua kev kawm. Cov tshuaj no yog tshuaj nyob ntawm seb tus luj ntawm tus me nyuam, tus nqi ntawm 2.5 ml ib 10 kg bodyweight. Yog hais tias tsim nyog, lub koob tshuaj yuav tau nce, tiam sis tsuas yog rau cov me nyuam laus tshaj ib xyoo. Tsis tas li ntawd, cov tshuaj yog tso tawm nyob rau hauv daim ntawv ntawm cov lozenges.

Prokinetics me nyuam tus kws kho yog tias koj tus me nyuam muaj:

• Ntuav.
• Xeev siab.
• Esophagitis.
• Qeeb digestion.
• Dyspeptic cov tsos mob.
• Nquag regurgitation.
• Gastro-esophageal reflux.
• Dysmotility ntawm tus mob huam.

Nws yuav tsum tau muab sau tseg tias nyob rau hauv lub heev thawj lub hlis ntawm lub neej tus me nyuam lub cev thiab tag nrho nws cov kev khiav dej num yog tsis heev tsim, yog li ntawd tag nrho cov tshuaj yuav tsum tau noj nyob rau hauv cov nruj kev saib xyuas thiab kev tswj ntawm tus kws kho mob. Nyob rau hauv cov ntaub ntawv ntawm overdose prokinetics tej zaum yuav ua neurological phiv nyob rau hauv cov me nyuam mos thiab cov me nyuam yaus.

Heev nrov ntawm cov niam txiv ntawm cov me nyuam mos siv herbal npaj, uas pab txoj kev zom cov zaub mov thiab thiaj li flatulence. Nws concentrates nyob rau lub hauv paus ntawm txiv hmab txiv ntoo ntawm fennel "Plantex".

Nws yog ib nqi hais tias ib tug ob peb lo lus hais txog cov nroj tsuag prokinetic.

tej yam ntuj tso pab

Yog li ntawd lub ntiaj teb no uas ib tug kho rau tej yam kab mob muaj peev xwm yuav nrhiav tau nyob rau hauv ib co nroj tsuag, tsuas yuav tsum paub - nyob rau hauv dab tsi. Yog li, lub npe hu tsob nroj prokinetics, uas tsim kho lub mob huam lub cev muaj zog muaj nuj nqi. Ntawm no yog ib co ntawm lawv:

• Fennel.
• Chamomile.
• Sambucus nigra.
• Dill.
• Oregano.
• Motherwort.
• Dandelion.
• Melissa.
• Cudweed.
• Plantain.
• Buckthorn olhovidnaya.

Daim ntawv teev cov nroj tsuag los pab txhim kho lub kom ntawm tus mob huam, muaj xws li ib tug loj tus naj npawb ntawm lwm hom muaj. Nws yuav tsum raug borne nyob rau hauv lub siab hais tias ib co txiv hmab txiv ntoo thiab zaub muaj cov nyhuv tib:

• Rutabaga.
• Dib pag.
• Zaub pob.
• Carrots.
• Beets.
• Taub dag.
• Cranberries.
• Txiv quav ntswv nyoos.

prokinetic zog manifest lawv tus kheej zoo heev nyob rau hauv cov zaub, thaum twg lawv npaj tshiab juices.

Nws yog ib nqi sau cia hais tias yuav tsum tsis txhob hloov cov tshuaj tsob nroj kab mob ntawm lub sij hawm ntawm exacerbation thiab tsis muaj kev noj kev haus ib tug kws kho mob.

phiv

Nws yog ib qho tseem ceeb heev uas tus tshiab tiam ntawm prokinetics muaj deb tsawg dua cov kev phiv tshaj thawj-tiam tshuaj muaj tus nquag muaj metoclopramide. Txawm li cas los, thiab feem ntau tshiab tshuaj muaj kev phiv:

• Mob taub hau.
• Txob taus.
• Qhov ncauj qhuav, nqhis dej.
• Spasm ntawm tus nqaij ntshiv ntawm lub hnyuv ib ntsuj av.
• Hives, tawm pob, khaus.
• Hyperprolactinemia.
• Cov me nyuam yuav manifest extrapyramidal cov tsos mob.

Tom qab discontinuation ntawm cov tshuaj phiv los yog kiag li.

Yog hais tias tus kws kho mob prescribes ib prokinetic, tshuaj daim ntawv teev yuav muaj xws li ntau yam tshuaj uas muaj ntau lub npe tab sis nrog ib tug active tshuaj. Nyob rau hauv rooj plaub no tus sab los yuav tau tib yam.

Nta ntawm kev siv ntawm prokinetic

Heev ua tib zoo yuav tsum tau muab prokinetic cov neeg uas muaj lub siab tsis ua hauj lwm thiab cov neeg pluag raum muaj nuj nqi. Tej cov neeg mob yuav tsum tau nyob rau hauv nruj kho mob saib xyuas.

Nrog ntev-lub sij hawm siv prokinetic cov neeg mob yuav tsum tau mus saib koj tus kws kho mob ntau zaus. Nrog ceev faj siv prokinetics nyob rau hauv cov me nyuam yaus, tshwj xeeb tshaj yog mus txog ib xyoos.

Ceev faj yog tsim nyog los muab cov tshuaj nyob rau hauv pab pawg neeg no ntawm cov neeg laus cov neeg mob.

Nyob rau hauv cov kev kho mob ntawm prokinetic yuav tsum tsis txhob koom rau hauv kev ua hauj lwm uas yuav tsum tau mloog thiab ceev cov lus teb.

Ua ntej kev yuav tsum nco ntsoov tham nrog ib tug kws kho mob. Los ntawm no nws yog nyob ntawm koj tus mob. Nws yog tsis tsim nyog noj tshuaj kom hloov nws analogue cog tsis tau kev noj kev haus koj tus kws kho mob.