Alkaline phosphatase: lub cai rau cov poj niam, cov txiv neej thiab cov me nyuam. Alkaline phosphatase nyob rau hauv cov ntshav: lub cai thiab sib txawv

Alkaline phosphatase yog ib qho enzyme kev, uas belongs rau cov pab pawg neeg ntawm hydrolases. Qhov no enzyme yuav tsum tau cai nyob rau hauv tag nrho cov qhov chaw ntawm tib neeg lub cev.

Tshwj xeeb tshaj yog faib enzyme active nyob rau hauv osteoblasts, plab hnyuv mucosa plhaub, nyob rau hauv lub mammary caj pas, lub tsev me nyuam, cov kua tsib ducts nyob rau hauv lub phab ntsa.

Hom ntawm alkaline phosphatase

Phosphatase yog muab faib ua ob peb hom:
- placental;
- raum;
- siab;
- E .;
- pob txha.

Alkaline phosphatase, raws li zoo raws li tag nrho cov enzymes zoo xws li cov mus rau nws, peb yuav tsum tau xeem kom dhau ib tug ntau yam ntawm tshuaj nyob rau hauv lub cev tib neeg. Yuav tsum tau yam tsawg kawg nkaus tus nqi ntawm alkaline phosphatase ua txoj kev tshua. Thiab yog hais tias lub cev muaj tej yam kev ua txhaum, nws yuav txhais tau hais tias lub alkaline phosphatase nce. Yog vim li cas rau qhov kev nce rau ntawm no enzyme tej zaum yuav txawv heev.

Yuav ua li cas puas alkaline phosphatase

Qhov no enzyme nqa tawm cov tshuaj tiv thaiv defosfolirovaniya. Qhov no cov tshuaj tiv thaiv muaj nyob rau hauv lub cleavage ntawm phosphate los ntawm organic tshuaj nyob rau lub molecular theem. Alkaline phosphatase nyob rau hauv cov ntshav muaj ib tug tsis tu ncua tej yam concentration. Lub enzyme muaj peev xwm sawv ntawm Identify phosphorus los ntawm tus xovtooj ntawm membrane. Nyob rau hauv tas li ntawd, phosphatase - ib qho kev ntsuas ntawm tus cai ntawm calcium-phosphorus metabolism. Qhov loj tshaj kev ua si ntawm lub enzyme yog qhia nyob rau hauv ib tug pH nruab nrab ntau 8,6-10,1. Li no lub npe - yog alkaline.

Alkaline phosphatase nyob rau hauv cov ntshav

Cov kab kev los ntawm indications ntawm tej ntshav ntawm alkaline phosphatase haum dav. Readings sib txawv los ntawm 44 IU / L mus 147 IU / L. Yuav tsum tsis tam sim ntawd ntshai yog alkaline phosphatase nce. Yog vim li cas tej zaum yuav kiag li harmless. Piv txwv li, tus nqi ntawm cov cev xeeb tub cov poj niam feem ntau yog me ntsis overstated. Nws kuj overestimated thiab cov tub ntxhais hluas, uas qhib rau theem ntawm tiav nkauj tiav nraug. Tag nrho cov no yog vim txoj kev loj hlob ntawm lub tsho me nyuam thiab cov pob txha, thiab tsis qhia ib tug ntau yam ntawm kev txawv txav nyob rau hauv tib neeg lub cev. Tsis tas li ntawd xam phosphatase nyob rau hauv lub hnub nyoog thiab pw ua ke ntawm tus neeg.
Thaum lub caij tsis muaj kev vib this, ces tus variation ntawm tsis cai nyob rau hauv lub reagents uas yog siv nyob rau hauv txoj kev kuaj rau kev tshawb fawb.

Alkaline phosphatase. cai

Ib tug kev xaiv rau kev txiav txim txawv txav nyob rau hauv lub cev yog alkaline phosphatase. Cov cai rau cov poj niam, cov txiv neej thiab cov me nyuam yog ib tug me ntsis txawv, nws yuav tsum tau muab sau tseg. Cov theem ntawm no enzyme nyob rau hauv lub cev nyob rau hauv cov poj niam yog me ntsis qis dua tus nqi rau cov txiv neej. Thaum cov me nyuam qhia ntawm cov theem ntawm no enzyme yog loj dua nyob rau hauv cov neeg laus.

Lub cev tus nqi ntawm alkaline phosphatase nyob rau hauv cov ntshav ntshav ntawm tus me nyuam yog:

- nyob rau hauv cov me nyuam mos: 245-255 IU / L;
- nyob rau hauv cov me nyuam hnub nyoog 1 txog 9 xyoo: 345-355 U / L;
- nyob rau hauv cov me nyuam hnub nyoog 10 mus rau 15 xyoo: 275-285 U / L;
- cov me nyuam hluas, hnub nyoog 16 mus rau 19 xyoo: 145-155 U / L.

Cov cai rau cov txiv neej:

- muaj hnub nyoog 21 mus rau 30 xyoo: 100-110 U / L;
- nruab nrab ntawm lub hnub nyoog ntawm 30 mus rau 45 xyoo: 110-120 U / L;
- nruab nrab ntawm lub hnub nyoog ntawm 46 rau 54 xyoo: 120-130 U / L;
- nruab nrab ntawm lub hnub nyoog ntawm 55 mus rau 70 xyoo: 135-145 U / L;
- muaj hnub nyoog ntawm '71: 180-190 U / L.

Nyob rau hauv cov laus, nyob ntawm seb rau hauv pem teb, ib tug me ntsis txawv alkaline phosphatase.

Cov cai rau cov poj niam yog:

- muaj hnub nyoog 21 mus rau 30 xyoo: 80-90 U / L;
- nruab nrab ntawm lub hnub nyoog ntawm 30 mus rau 45 xyoo: 90-100 U / L;
- nruab nrab ntawm lub hnub nyoog ntawm 46 rau 54 xyoo: 105-115 U / L;
- nruab nrab ntawm lub hnub nyoog ntawm 55 mus rau 70 xyoo: 125-135 U / L;
- muaj hnub nyoog ntawm '71: 155 -165ed / l;

Nws muaj peev xwm yuav xaus lus tias tus txiv neej nrog kev hwm rau cov poj niam cov nuj nqis, ib tug me ntsis kom alkaline phosphatase. Cov cai rau cov poj niam yog tsawg tshaj li cov txiv neej lub nqi ntawm txog 20 U / L.

Yog vim li cas kom muaj zog cov nqi ntawm alkaline phosphatase

Nws tau raug hais tias, nyob rau hauv uas nyob hauv lub alkaline phosphatase. Norma yog nce, thiab no tej zaum yuav tsis ua rau ib tug uas muaj feem yuav mus noj qab haus huv. Tab sis nws tshwm sim thiab vice versa, thaum qhov kev nce rau ntawm lub Performance index yog tus thawj thiab muaj tseeb ceeb toom tias nyob rau hauv lub cev ntawm tus neeg mob muaj cai tseem ceeb ua txhaum.

Nyob rau qhov kev nce rau hauv lub qhia ntawm lub enzyme yuav ua rau:

Nyob rau hauv ib feem ntawm lub biliary ib ntsuj av tau thiab lub siab:

- ib tug mob ntawm cov kua tsib ciav;
- daj ntseg, uas muaj peev xwm ua rau rhuav txhua ntawm cov kua tsib ducts;
- lub siab ua cancer;
- cirrhosis ntawm cov kua tsib ducts, provoked los ntawm kev phais cov txheej txheem;
- pob zeb nyob rau hauv cov kua tsib ducts;
- cancer ntawm lub plab los sis txiav;
- mob npuas paug;
- Kis kab mononucleosis;
- tej keeb kwm kab mob siab. Nyob rau hauv no kab mob nyob rau hauv txog 3-quav nce alkaline phosphatase.

Yog vim li cas nyob rau ib feem ntawm cov cov pob txha:

- Paget tus kab mob. Tus kab mob no yog yus muaj los ntawm txawv txav pob txha loj hlob, raws li zoo raws li lub cuam tshuam nyob rau hauv tej qhov chaw ntawm lub pob txha qauv. Nyob rau hauv kab mob no, muaj ntau heev theem ntawm cov enzyme nyob rau hauv saib xyuas;
- pob txha mob;
- osteosarcoma, uas yog ib tug kab mob qog hlav rau tus pob txha;
- osteomalacia provoked los ntawm calcium deficiency (osteomalacia).

Lwm yam yog vim li cas:

- myocardial infarction;
- hyperparathyroidism, uas yog ib tug hormonal kab mob, thaum nws yog cai ib tug dhau heev lawm ntawm parathyroid lawm, parathyroid tsim. Vim hais tias ntawm yog dab tsi nws yog leaching ntawm calcium los ntawm cov pob txha;
- plab hnyuv perforation (los ntawm-kev puas tsuaj);
- ulcerative mob plab.

Yog vim li cas rau cov uas tsis theem ntawm alkaline phosphatase

Nws tsis yog ib txwm yog ib tug txawv yog tsa alkaline phosphatase. Cov cai rau cov poj niam thiab cov txiv neej tej zaum lawv yuav diverge thiab down.

A lub caij nplooj zeeg phosphatase theem yuav muaj kev cuam tshuam:

- ntshav nyob rau hauv loj koob tshuaj;
- ntshav liab tsawg nyob rau hauv mob loj heev;
- hypothyroidism (tsawg thyroid muaj nuj nqi);
- gipofostataziya (congenital tsawg tus kab mob uas ua cov softening ntawm cov pob txha);
- tsis txaus cov nqi ntawm cov zinc thiab magnesium nyob rau hauv lub cev;
- tsis ua hauj lwm ntawm lub tsho me nyuam (nyob rau hauv cev xeeb tub cov poj niam).

Yuav ua li cas muaj feem xyuam rau lub sij hawm

Yuav kom nce:

- Thaum lub sij hawm cev xeeb tub, lub tsho me nyuam muaj alkaline phosphatase. Cov cai rau cov poj niam nyob rau hauv lub sij hawm no tsis yog yuav tsum tau ntev;
- tom qab pob txha lov kuj sau ntawv ib tug nce tus nqi ntawm alkaline phosphatase;
- vim cov me nyuam thiab cov tub ntxhais hluas tau ib tug sai kev loj hlob ntawm cov pob txha, tus nqi ntawm lub enzyme nce qib ntawm kev sib tham;
- kom cov theem ntawm phosphatase nyob rau hauv cov ntshav yuav ua tau, thiab ib co tshuaj, xws li "Paracetamol", "aspirin", "Allopurinol", ntau yam tshuaj tua kab mob, thiab ib tug ntau yam ntawm lwm yam tshuaj;
- ntaub ntawv enzyme defosfolirovaniya kom theem tau cai, tom qab txias, coj nyob rau ntawm qhov mus kuaj ntshav.

Nyob rau txos ntawm lub theem ntawm no enzyme yuav ua rau qhov ncauj contraceptives.

Analysis rau alkaline phosphatase

Thaum lub sij hawm ntawm kev noj lub tsom xam ntawm alkaline phosphatase nyob rau hauv cov ntshav rau tus neeg pub ntshav ntshiab ntxiv txog reagents yuav muaj teebmeem rau cov phosphatase. Tom qab ntawd, pes tsawg hom kev kawm, lub concentration ntawm cov khoom tau yog ntsuas. Nyob rau hauv txhua cov ntaub so ntswg, muab nws cov hnyuv, lub siab los yog lub tsev me nyuam, muaj ib tug tej yam zoo ntawm alkaline phosphatase. Thaum lub sij hawm lub tsom xam ntawm lub measured concentration ntawm kev enzyme.

Yuav kom tes tshaj lub tsom xam ntawm ib tug ntshav mus rau lub enzyme, tus neeg mob yuav tsum tau ib tug ob peb feeb. Nyob rau hauv tej rooj plaub, cov neeg muaj lub plab tom qab noj mov ntau ua alkaline phosphatase. Nyob rau hauv cov ntaub ntawv no, tus tsom xam tau tej zaum yuav distorted. Yog li ntawd, tus neeg mob yuav tsis siv sij hawm khoom noj khoom haus los yog haus dej ua ntej tus me nyuam ntawm tus tsom xam.

Tsaug rau niaj hnub kuaj txoj kev, xeem tau yuav tsum tau npaj tom qab ib tug ob peb teev.

Raws li nyob rau tag nrho cov ntaub ntawv, peb yuav xaus uas qhov tsawg kawg nkaus alkaline phosphatase nyob rau hauv cov ntshav - lub cai. Ua lub theem ntawm no enzyme yuav raws li cov lus ceeb toom txog tej yam hloov los yog kev ua txhaum, thiab tsis muaj kiag li ua kev txhawj xeeb. Nyob rau hauv txhua rooj plaub, qhov no yog tsis yog qhov kawg qhia txog cov kev hloov nyob rau hauv tib neeg lub cev.