Tshuaj rau TPO tshuaj

Rau hnub tim, thoob ntiaj teb cov teeb meem ntawm lub qog caj pas tsis poob nws qhov tseeb. Tsis muaj iodine nyob rau hauv lub cev yog cai nyob rau hauv 40% ntawm cov neeg laus thiab 50% cov me nyuam. Qhov no yog vim tsis tau tsuas yog rau cov roj ntsha zoo tshaj, tab sis kuj tsis zoo tus ntawm ib puag ncig. Nyob rau hauv cov ntaub ntawv no, lub inorganic iodine rau lub synthesis ntawm cov tshuaj hormones xws li T3 thiab T4, uas yog nyob rau ntawm lub xov tooj ntawm pituitary thyroid stimulating lawm (TSH), thyroid tswj kev ua si.

Nws yuav tsum tau hais tias yog hais tias tus thyroid caj pas yog tsis txaus kom muaj raws li nws cov kev khiav dej num, tej yam kab mob (autoimmune) tsim nyob rau hauv lub cev. Yog li, kom paub tias txoj kev tshawb no AT TPO tshuaj tej zaum yuav qhia ib tug txhoj puab heev tiv thaiv kab mob raws li txoj cai nrog rau kev hwm mus rau hauv lub cev. Uas yog vim li cas lub ntau hom ntawm lub qog kab mob yog muab rau cov kev kawm txog cov ntshav TSH theem thiab muaj cov tshuaj mus rau lub AT TPO. Yog hais tias tus tom kawg yog tseem pom, ces ib tug hais lus ntawm ib tug kab mob autoimmune.

AT TPO nruab nrab yog ib qho enzyme muab kev koom tes nyob rau hauv lub synthesis ntawm cov tshuaj hormones thiab SHCHZ thaum lub sij hawm iodization cov tshuaj hormones. Nws yog ib tug tswv cuab tireyodnogo antigen.

Yog vim li cas rau kev tsom xam yuav pab raws li ib tug mob ntawm cov kab mob xws li goiter, hypo- thiab hyperthyroidism, Graves kab mob, tireoinid drumsticks edema. Tsis tas li ntawd, tus tsom xam yog tshuaj thaum lub sij hawm cev xeeb tub los mus txiav txim kev pheej hmoo ntawm tireoinita tom qab muab yug (10% ntawm cov poj niam muaj tus kab mob no).

Nws yuav tsum tau muab sau tseg hais tias TPO tshuaj, cov nqi ntawm uas ib tug neeg laus yog 5.6 U / ml, nyob rau hauv lub cev muaj active iodine tsim. Tshuaj rau qhov no enzyme tiv thaiv nws cov kev ua si, yog li txo lub tso pa tawm ntawm cov tshuaj hormones T4 thiab T3. Tab sis tsis nyob rau hauv tag nrho cov mob, cov thyroid peroxidase qhia lub xub ntiag ntawm ib tug autoimmune txheej txheem.

Txoj kev tshawb no yog indispensable rau qhov mob ntawm lub qog kab mob. Cov tsos ntawm kev ua txhaum nyob rau hauv nws cov hauj lwm yog thawj kos npe rau ntawm hypothyroidism. Thaum uas siv cov rhiab heev txoj kev diagnostikiAT TPO, ces tus kab mob no yog pom nyob rau hauv 94% ntawm cov neeg mob nrog Graves 'kab mob - 84%, cov thyroid kab mob neautoimunnye - 15% ntawm cov neeg. Tsis tshua muaj ntau ntau cov ib qho enzyme feem ntau pom nyob rau hauv cov neeg noj qab, li ntawd, nyob rau hauv cov ntaub ntawv no rau lo lus nug ntawm kev loj hlob ntawm ntau yam kab mob yog tsis zoo to taub.

Nws yuav tsum tau muab sau tseg tias nyob rau hauv lub rooj plaub uas lub AT TPO nce, qhov no qhia xws li ib tug txheej txheem raws li hypothyroidism. Qhov no zoo ntawm txoj kev ua txhaum zoo nkaus li raws li ib tug tshwm sim ntawm deceleration antibody TPO kev ua si, iodine oxidation tus nqi, thiab, yog li ntawd, cov me nyuam ntawm nws active daim ntawv. Nyob rau hauv cov ntaub ntawv no, cov thyroid hormones yog tsis tsim.

Txoj kev tshawb no mus txog ob peb theem. Nyob rau hauv tib neeg, cov ntshav no yuav, raws li uas tus txiav txim theem ntawm TSH thiab T4. Nyob rau hauv cov ntaub ntawv ntawm tej T4 kev kawm thiab cov uas tsis muaj TSH, nqa tawm ib txoj kev tshawb no ntawm T3. Nyob rau hauv lub caij nyoog kawg no cov ntaub ntawv, koj yuav tsum ua kom tiav ib daim ntawv ntsuam rau AT TPO tshuaj.

Yog li, lub indications rau txoj kev tshawb no muaj peev xwm pab tau raws li ib tug xav tias goiter, hypothyroidism thiab Hashimoto lub thyroiditis. Tab sis nws yuav tsum tau nco ntsoov tias tsis tuaj kawm ntawv ntawm cov tshuaj rau cov thyroid peroxidase AIT tsis txwv cov nyob rau hauv lub cev. Tus foundations ntawm no enzyme nyob rau hauv cov ntshav tsis muab tsis cog qoob loo nyob rau hauv lub xub ntiag ntawm ib autoimmune kab mob, txij thaum nyob rau feem ntau cov AT TPO yog tam sim no nyob rau hauv tsis noj qab nyob zoo neeg.

Los ntawm tag nrho cov no nws hais ntxiv hais tias lub nrhiav kom tau ntawm no enzyme yog tsim nyog los nqa tawm ib qho kev daim ntawv ntsuam xyuas nrog rau cov aim los mus tshem tawm cov kev pheej hmoo ntawm AIT.

Yog li, tsis hais ntawm qhov teeb meem no, cov thyroid peroxidase yog txaus rhiab xeem autoimmune txawv txav nyob rau hauv lub qog, txawm li cas los, xws kev tshawb fawb yog siv nyob rau hauv yuav luag txhua txhua lub tsev kho mob.