"Phenylbutazone" (ntsiav tshuaj): cov lus qhia rau kev siv, analogues, cov nqi thiab xyuas

Los ntawm dab tsi thiab yuav ua li cas siv tshuaj "Phenylbutazone" (ntsiav tshuaj)? Cov lus qhia rau kev siv, indications, zog thiab cov yam ntxwv ntawm cov tshuaj yuav tsum nyob rau hauv no tsab xov xwm.

Kuj muaj koj yuav nrhiav tau cov lus qhia txog yuav ua li cas npaum li cas nws cov nqi, hais tias txhais tau hais tias yog dab tsi cov khoom xyaw yog muaj nyob rau hauv nws cov muaj pes tsawg leeg (active thiab tsaug zog), thiab yog hais tias nws muaj tej yam kev mob tshwm sim.

Cov khoom xyaw thiab ntim ntawm tshuaj

Yuav ua li cas yog lub Cheebtsam muaj nyob rau hauv cov tshuaj "Phenylbutazone"? Ntsiav tshuaj comprise cov active ingredient xws li phenylbutazone. Tsis tas li ntawd cov tshuaj muaj xws li: qos yaj ywm starch, primelloza, magnesium stearate, sodium bicarbonate, talc thiab silica.

Tshuaj "Phenylbutazone" (ntsiav tshuaj) yog muag nyob rau hauv sawv hlwv packs, uas yog muab ntim rau hauv cov nkev ntawv ntim.

Pharmacodynamic yam ntxwv ntawm cov tshuaj

Koj puas paub hais tias qhov no yog ib tug yeeb tshuaj raws li "Phenylbutazone"? Xyuas cov tub txawg qhia tias nws yog ib tug uas tsis yog-tshuaj anti-inflammatory tus neeg saib xyuas uas muaj antipyretic thiab analgesic nyhuv.

Cov hauj lwm zoo ntawm no neeg sawv cev yog txuam nrog nws muaj peev xwm inhibit qhov kev ua si ntawm cyclooxygenase. Raws li ib tug ntawm xws li tej yam slows tus synthesis of prostaglandins.

Saib medicament tej lub reabsorption ntawm ntsev thiab dej nyob rau hauv lub raum tubules. Nws kuj eliminates tus mob thiab thiaj li o, uas yog feem ntau nrog o.

Yuav ua li cas puas muaj tus kho nyhuv "Phenylbutazone" tshuaj? Ntsiav tshuaj txo mob tej pob txha (thaum lub sij hawm cov lus tsa suab thiab nyob so), raws li zoo raws li lawv txo muaj los yog kev nce ntau yam ntawm cov lus tsa suab.

Anti-inflammatory kev txiav txim ntawm no neeg sawv cev yog lom zem ntau superior rau "Amidopyrine" zoo xws li cov tshuaj.

Thaum gout active medicament doubles urate feem nyob rau hauv cov zis, thiab thiaj li tus nqi ntawm cov ntshav.

Tsis tas li ntawd nco ntsoov tias cov tshuaj "Phenylbutazone" (ntsiav tshuaj), cov lus qhia rau kev siv uas yog kos rau hauv cov pob nrog blisters, thiaj li mob thiab o cov tsos mob thaum thrombophlebitis (postoperative thiab hemorrhoidal leeg).

Kev tig tau cov yam ntxwv ntawm cov kev npaj

tshuaj "Phenylbutazone" (ntsiav tshuaj) nyob qhov twg cov absorbed? Phau Ntawv Qhia hais tias lub siab haum ntawm cov tshuaj los ntawm tus mob huam tshwm sim. Nws bioavailability yog hais txog 87-90% thiab lub siab tshaj plaws ntshav concentration yog cai tom qab 60-150 feeb tom qab thawj coj.

Los ntawm cov tshuaj ntshav maj kis mus rau hauv cov nqaij thiab kabmob, thiab kuj penetrates mus rau hauv tus txha kab noj hniav thiab los ntawm cov ntshav-hlwb barrier.

Metabolism hauv ntawm no neeg sawv cev nyob rau hauv lub siab. Thaum nws ib nrab-lub neej yog 19-25 teev. Yog tso zis los ntawm lub raum thiab lub medicament los ntawm lub digestive ib ntsuj av.

Indications rau lozenges

Nyob rau hauv tej rooj plaub, muab cov tshuaj "Phenylbutazone"? Ntsiav tshuaj zoo manifest lawv tus kheej nyob rau hauv cov kev kho mob ntawm:

• ankylosing spondylitis;
• osteoarthritis;
• psoriatic mob caj dab ;
• lupus thiab mob caj dab rheumatoid;
• tenosynovitis thiab bursitis;
• gouty mob caj dab ;
• algodismenorei;
• post-operative mob;
• hniav thiab mob taub hau.

Tsis tas li ntawd, qhov no tshuaj yog siv rau cov nyem ntawm tsis xis nyob nyob rau hauv neuralgia, sciatica, thiab kub yus.

Contraindications tau txais tshuaj

Yuav ua li cas npaum li cas yog peb pom tau hais tias ib tug yeeb tshuaj? Yuav ua li cas yog nws nqi? "Phenylbutazone" yuav yuav tau nyob tej chaw muag tshuaj rau ib tug nqi pheej yig heev. Peb yuav nthuav nws nyob rau thaum xaus ntawm qhov tsab xov xwm.

Puas muaj tej contraindications rau cov tshuaj no? Raws li cov lus qhia, cov tshuaj yuav tsis raug siv thaum:

• los ntshav los ntawm tus mob huam nyob rau hauv keeb kwm;
• intolerance ntawm acetylsalicylic acid;
• lub plawv atherosclerosis tsis meej;
• npau taws me ntsis rau phenylbutazone;
• hloov hlwb pob txha hluav;
• exacerbation ntawm ulcerative mob plab thiab peptic rwj kab mob ntawm lub digestive ib ntsuj av tau;
• decompensated lub plawv tsis ua hauj lwm;
• hepatic thiab lub raum tsis ua hauj lwm;
• hyperkalemia;
• nyob rau hauv lub hnub nyoog ntawm 12 xyoo;
• cev xeeb tub, tshwj xeeb tshaj yog nyob rau hauv thawj thiab thib peb trimesters;
• thaum noj lwm yam tshuaj uas muaj phenylbutazone.

Cov lus qhia rau kev siv "Phenylbutazone" tshuaj

Raws li cov kev qhia ntawv npaj "Phenylbutazone" coj lus tom qab noj mov 150 mg plaub zaug ib hnub twg. Qhov siab tshaj plaws ib koob tshuaj ntawm cov tshuaj yog 200 mg, thiab txhua hnub - 600.

Lub caij ntawm txoj kev kho nrog no neeg sawv cev nyob rau tus kab mob thiab heev ntawm tus neeg mob tus mob. KOOB sib npaug zos rau 400-600 mg ib hnub twg, muaj peev xwm ntawm kev txo tus nqi ntawm cov zis muaj ntshav qab zib insipidus.

Hluas los ntawm 12 xyoo ntawm cov ntsiav tshuaj "Phenylbutazone" taw 75 mg peb zaug ib hnub twg. Yuav kom tiv thaiv irritant nyhuv ntawm cov tshuaj no rau tus mucosa ntawm lub plab nws yog pom zoo kom haus dej haus mis nyuj sov.

Nyob rau hauv lub xub ntiag ntawm articular kab mob medicament nyhuv amplified los ntawm simultaneous thawj coj "prednisolone" (Txoj kev lis ntshav, i.v.).

Nws yuav tsum tau muab sau tseg tias yuav ua tau kom lub kho tau "Phenylbutazone" ntsiav tshuaj ke nrog tshuaj pleev "Phenylbutazone".

Phiv tshua tom qab haus ntawm cov ntsiav tshuaj

Txais tos "Phenylbutazone" ntsiav tshuaj tej zaum yuav ua rau cov hauv qab no mauj tshua:

• xeev siab, mob plab, dyspepsia;
• ntuav, aphthous stomatitis, kub siab;
• ulceration ntawm lub qog ua kua membrane ntawm cov hnyuv, raws plab, ringing nyob rau hauv lub pob ntseg;

• hnyuv los ntshav;
• gingival los ntshav thiab hemorrhoids;
• ntshav siab;
• kev cuam tshuam ntawm lub siab;
• mob taub hau, anemia, kev nyuaj siab, leukopenia, kiv taub hau;
• nkees nkees, agranulocytosis, excitement, thrombocytopenia.

Sab los nyob rau hauv cov ntshav thiab yuav tsum tau discontinuation ntawm cov tshuaj kho mob mus rau ib tug tshwj xeeb.

Sodium thiab dej tuav nyob rau hauv lub cev uas txuam nrog kev noj "phenylbutazone" markedly impairs tus mob ntawm cov neeg mob uas kub siab thiab CHF. Qhov no lub sij hawm ntawd kuj yuav tsum tau kev kho me ntsis nyob rau hauv kev kho mob.

Zoo ib yam li cov tshuaj thiab cov nqi

"Phenylbutazone" ntsiav tshuaj (20 daim) yuav tsum tau muas rau 40-70 rubles.

Raws li rau lub analogy, raws li lawv siv cov nram qab no txhais tau tias: "Phenylbutazone-OBL", "Artrizin", "phenylbutazone", "Butalidon".

Xyuas ntawm cov neeg mob nyob rau hauv cov tshuaj

Tam sim no uas koj paub tias dab tsi cov tshuaj "Phenylbutazone" nqi. Cov ntsiav tshuaj no yog pheej yig, tab sis kev xav txog kev xyuas, ces lawv yuav tsum tau hais hauv qab no.

Ntsuam xyuas cov lus teb ntawm cov neeg mob nyob rau hauv cov tshuaj no, peb yuav xyuam xim xaus hais tias nws zoo manifests nws tus kheej nyob rau hauv tag nrho cov txha thiab cov nqaij ntshiv. Tab sis, nyob rau hauv tas li ntawd mus zoo tswv yim, cov neeg mob feem ntau ua rau nws, thiab tsis zoo lus. Raws li lawv, "Phenylbutazone" tshuaj feem ntau ua rau cov teeb meem ntawm tus mob huam thiab cov ntshav lub cev. Nyob rau hauv no hais txog, feem ntau cov kws kho mob pom zoo kom muab noj cov tshuaj no, thiab hloov nws nrog ib tug muaj kev ruaj ntseg tsheb.