"Neostigmine" (txhaj tshuaj)

"Neostigmine" (tshuaj) yog ib tug hluavtaws tshuaj, lub ntsiab active tshuaj uas ua raws li neostigmine methylsulfate.

Tej kev npaj no muaj ib tug qhia tau anticholinesterase kev ua si, thiab yog li ntawd tom qab nws siv pab cov kev hloov ntawm excitation los ntawm paj mus rau ib tug skeletal leeg, hauv nruab nrog cev thiab lub qhov muag kom nrov loj tag nrho cholinergic los, kuj vim hais tias nws yog enhanced hnyuv kom, tsub kom lub suab nrov ntawm bronchial, zais zis, endocrine qog thiab secretion.

Kev npaj "Neostigmine" muab tsis tau tsuas yog nyob rau hauv daim ntawv ntawm ib tug tov rau txhaj, tab sis kuj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, granules, ntawm uas npaj qhov ncauj ncua kev kawm ntawv (rau cov me nyuam).

indications

Hais tias medicament yog siv nyob rau hauv lub xub ntiag ntawm myasthenia, tuag tes tuag taw thiab paresis, mob ntawm lub cev muaj zog ua si tom qab lub hlwb raug mob, neuritis, encephalitis tom qab, polio thiab tuberculous meningitis.

Nws kuj yog siv thaum qhov yuav tsum tau rau kev kho mob ntawm optic paj Atrophy, los txo intraocular siab nyob rau hauv glaucoma yog nce, thiab yog hais tias tsim nyog constriction ntawm tus menyuam. Nyob rau hauv cov kab mob, cov tshuaj no yog siv nyob rau hauv daim ntawv ntawm qhov muag dauv.

Txhais tau hais tias "Neostigmine" (tshuaj) yog siv rau induction ntawm zog, thiab nws muaj ib tug analgesic nyhuv. Feem ntau cov tshuaj siv nyob rau hauv cov kev kho mob, qhov chaw uas nws yog kho siv cov atony ntawm lub plab, zais zis thiab tso quav, nws yog noj ntawm ncauj.

Tshuaj "Neostigmine" tshuaj, raws li zoo li lwm yam ntaub ntawv ntawm qhov kev siv yeeb tshuaj, yog siv heev dua lwm yam los ntawm cov tshuaj, thiab cia nws ywj siab cov kev pab cuam muaj txwv tsis pub.

Yog hais tias cov tshuaj yog thov hais lus, nws cov koob tshuaj rau ib tug neeg laus yog los ntawm ib tug puas mus rau kaum tsib hundredths grams thiab coj mus rau 3 lub sij hawm ib hnub twg. Rau cov me nyuam nyob rau hauv lub hnub nyoog ntawm kaum - ib tug thousandth ntawm ib tug gram rau txhua tom ntej xyoo, tab sis tsis muaj ntau tshaj li 0.01 grams tauj ib hnub.

Kev npaj "Neostigmine" (tshuaj) yuav muab ob qho tib si subcutaneously thiab intramuscularly nyob rau hauv ib tug npaum li ntawm 1 ml ntawm ib tug 0.05% tov yog muab rau cov me nyuam raws li ib feem kaum ml ib xyoo, tab sis tsis ntau tshaj li 0.75 milliliter, tag nrho cov ua nyob rau hauv ib los yog ob lub sij hawm. Tag nrho cov ntev ntawm kev kho mob nyob rau hauv lub heev ntawm tus kab mob no thiab yuav ua tau los ntawm 15 mus rau 40 hnub, thiab nyob rau hauv tej rooj plaub txawm ntev.

Yog hais tias muaj yog ib tug tsis muaj zog ua hauj lwm rau, cov tshuaj "Neostigmine" (ampoules) yuav tsum tau siv rau subcutaneous tshuaj , thiab nyob rau tib lub sij hawm qhia ib tug txhais tau tias ntawm "Atropine". Qhov no yog ua ib zaug xwb nyob rau thawj txais neeg kawm los yog kev txhaj tshuaj. Tsis tas li ntawd, cov tshuaj yog muab lus nyob rau hauv ib tug npaum li ntawm 0,003 g txhua txhua 40 feeb mus rau 6 lub sij hawm, thiab tshuaj ua 0.05% tshuaj ntawm 2 lub sij hawm ib teev nyob rau hauv 1.0 ml.

Rau ib tug neeg laus, lub siab tshaj plaws txhua txhua hnub koob tshuaj yog 0.05 g, thiab cov hauj lwm yuav tsum tsis txhob ntau tshaj kaum tsib hundredths grams. Nrog hais txog tshuaj, lub siab tshaj plaws tshuaj ib hnub twg yog 0.006 g, ib tug tib koob tshuaj tsis muaj ntau tshaj li ob thousandths ntawm ib tug kab.

Tej kev phiv

Tom qab daim ntawv thov ntawm hais tias formulation yuav tshwm sim bradycardia, raws plab, xeev siab, tsis muaj ntshav siab, muaj zog bronchial secretion, tsis muaj zog thiab tsis haum.

Yog hais tias ib tug neeg twb mob raws plab thiab mob plab, raws li zoo raws li pouring tawm hws, nws qhia tias ib tug tshuaj lom nyhuv txhais tau tias "Neostigmine". tshuaj "Atropine" subcutaneously txhaj nyob rau hauv xws li mob.

Koj siv tsis tau cov tshuaj nyob rau hauv lub xub ntiag ntawm, qaug dabpeg, nce nqaij laus, bronchial hawb pob, angina, atherosclerosis, thiab intolerance ntawm cov tshuaj no.

Tshuaj "Neostigmine": xyuas

Teb zoo mus no npaj cov neeg uas raug kev txom nyem los ntawm myasthenia Heavy kev, raws li nws yog nqa tawm nrog kev pab los ntawm qhov txij nkawm txoj kev kho.

Qhov ratio ntawm cov neeg mob mus rau lub chaw "Neostigmine" yog tsis meej xwm yog ib co ua lawv tus kheej tsis tu ncua tshuaj, thaum lwm tus neeg muaj resorted mus rau siv nws tsuas yog nyob rau tsawg zaus, thiab ib txhia tsis tso. Raws li ib sab nyhuv, ntau cov neeg mob pom cov tsos raws li ib tug qhov ncauj qhuav thiab ntau salivation thiab qaug dab peg.