"Moxonidine": cov lus qhia rau kev siv, tiag tiag

Yuav ua li cas yog tus kho "Moxonidine"? Cov lus qhia rau kev siv ntawm no lub cuab tam, xyuas txog nws, contraindications, thiab analogs yog piav nyob rau hauv kom meej nyob rau hauv no tsab xov xwm. Nyob rau hauv tas li ntawd, peb yuav qhia rau koj hais txog dab tsi peb xav yog npaj txhais tau tias, yog hais tias nws muaj tej yam kev tshwm sim thiab hauv daim ntawv nyob rau hauv uas nws yog muab.

Tus duab thiab muaj pes tsawg leeg ntawm cov tshuaj

tau mus yuav cov tshuaj "Moxonidine" Nyob rau hauv dab tsi daim ntawv no? Qhov no tshuaj yog tsuas yog muag nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj. Lawv active caij yog ib tug xws tshuaj raws li moxonidine. Nrog kev xav txog ntxiv Cheebtsam uas hais txog thereto cellulose microcrystalline, castor roj, Aerosil A-380, hydroxypropylcellulose, magnesium stearate thiab Tween-80.

Ntsiav tshuaj yog muag nyob rau hauv ib cov duab los qhia pob. Ib pob tej zaum yuav 98, 60, 56, 42, 40, 30, 28, 20, 14 thiab 10 ntsiav tshuaj.

Lub pharmacological thaj chaw ntawm cov tshuaj

Yog vim li cas kuv yuav tsum tau noj tshuaj "Moxonidine"? Cov lus qhia rau kev siv hais tias qhov no npaj yog ib qho antihypertensive tshuaj. Nws mechanism ntawm qhov kev txiav txim cov lus dag nyob rau hauv lub fact tias cov active tshuaj txhais tau tias muaj feem xyuam rau lub hauv paus mus rau hauv cov ntshav siab kev cai. Nyob rau hauv lwm yam lus, moxonidine - imidazoline receptor agonist yog (feem ntau).

Cov tshuaj cheeb qhov uas cov kev ua si ntawm lub vasomotor chaw, kom txhob muaj cov nqis sympathetic ntxim rau cov hlab plawv system. Lub siab (diastolic thiab systolic) txo maj.

medicament xam tau tias yog los ntawm peb yog txawv los ntawm lwm yam antihypertensive sympatholytic cov neeg ua hauj nyob rau hauv hais tias nws muaj tsuas ib tug me me affinity rau lub alpha-2-adrenoretseptoramm. Qhov no qhia rau cov uas tsis muaj tshwm sim rau ib lub qhov ncauj qhuav thiab ua kom loog.

Peb tsis tau hais tias moxonidine yuav ua rau kom insulin rhiab heev index (kwv yees li 21 feem pua) nyob rau hauv cov neeg uas muaj rog.

Tshuaj ntawm cov tshuaj

Qhov twg cov tshuaj yog absorbed, "Moxonidine"? Tus neeg siv daim ntawv thov hais tias tom qab tau txais medicament tam sim ntawd thiab yuav luag tag absorbed rau hauv lub Upper digestive ib ntsuj av.

Bioavailability (tsis) ntawm lub cuab tam yog 88 feem pua. Qhov siab tshaj plaws concentration yog tiav tom qab caum tsib feeb. Nyob rau hauv cov ntaub ntawv no, kev noj ntawm cov zaub mov yog tsis ntxim rau cov tshuaj ntawm lub active caij tsis tau.

Kev sib txuas lus nrog rau cov ntshav protein yog hais txog 7.3%. Qhov loj metabolite ntawm Moxonidine Moxonidine ua lub cev qhuav dej, thiab guanidine derivatives.

Lub ib nrab-lub neej ntawm moxonidine thiab nws cov metabolites yog 150 thiab 300 feeb feem.

Tom qab haus rau nees nkaum plaub teev ntawm yeeb tshuaj tas los ntawm ob lub raum nyob rau hauv ib tug ntim ntawm 90%. Tsis tas li ntawd, lub active tshuaj los thiab los ntawm cov hnyuv.

Indications rau kev siv ntawm ib tug kws kho ntaus ntawv

Nyob rau hauv tej rooj plaub, prescribers 'Moxonidine "? Kev siv cov tshuaj no qhia tsuas yog hais tias xws pathology li tawg arterial.

Contraindications rau kev siv ntawm ib tug kws kho ntaus ntawv

Nyob rau hauv tej rooj plaub, cov kws kho mob tsis txhob muab tshuaj rau lawv cov neeg mob 'Moxonidine "? Cov lus qhia rau kev siv ntawm cov tshuaj no muaj tsis yog ib tug ntev heev daim ntawv teev cov contraindications. Xav txog nws tam sim no.

Yog li ntawd contraindications rau kev siv ntawm "Moxonidine" npaj muaj yam nram qab no:

• qhia AV-thaiv 2 thiab 3 degrees, SSS;
• bradycardia (tsawg tshaj li 50 neeg ntaus ib feeb);
• tub hluas ntxhais hluas thiab cov me nyuam lub hnub nyoog (18 xyoo);
• mob thiab mob lub plawv tsis ua hauj lwm;
• tus me nyuam pub lub sij hawm;
• Npau taws me ntsis rau lub active caij.

Cov tshuaj "Moxonidine": cov lus qhia rau kev siv

Testimonials txog qhov no medicament yuav tsum tau nthuav tawm nyob rau thaum xaus ntawm qhov tsab xov xwm. Tam sim no kuv xav qhia rau koj txog yuav ua li cas siv cov tshuaj kom zoo ua ntej peb.

Tshuaj "Moxonidine" tsuas yog sab hauv. Ntau npaum nyob rau hauv thaum ntxov tshuaj kho yuav tsum tau 200 micrograms ib zaug ib hnub twg. Thaum lub sij hawm, koj muaj peev xwm coj 400 micrograms.

Nws yuav tsum tau ib tug neeg kom haum ntawm lub hnub nyiaj ntawm cov tshuaj nyob ntawm seb lub tolerability ntawm yeeb tshuaj kho. Raws li cov lus qhia, lub siab tshaj plaws ntau npaum ntawm medicament ib hnub twg yog 600 mg (muab faib mus rau hauv ob kauj ruam).

Rau cov neeg mob raum insufficiency (ntsis thiab mob), thiab cov neeg uas yog nyob rau hauv hemodialysis, cov tshuaj yog muab nyob rau hauv ib tug npaum li ntawm 200 mg ib zaug ib hnub twg. Yog hais tias tsim nyog (nrog zoo endurance), lub teev ntau npaum yuav muab ntau zog rau lub siab tshaj plaws (i.e. 400 mg).

Cov nyom zoo tom qab tau txais medicament

Puas muaj tus tshwm sim los ntawm cov tshuaj "Moxonidine"? Testimonials txog nws hais tias tej zaum cov tshuaj ua tau ua rau ib tug deterioration ntawm kev noj qab nyob. Xav txog ib daim ntawv teev kev phiv muaj cov kev qhia ntawv:

• Lub paj hlwb (central): mob taub hau, tsaus muag, kiv taub hau, thiab somnolence.
• Hnyuv: ntuav, qhov ncauj qhuav, raws plab, dyspepsia thiab xeev siab.
• hlab plawv system: bradycardia, cim nco nyob rau hauv cov ntshav siab, orthostatic hypotension.
• Ntawm daim tawv nqaij thiab subcutaneous cov ntaub so ntswg mob: angioneurotic edema, pruritus thiab daim tawv nqaij pob.
• Hlwb kev ntshawv siab: nervousness thiab insomnia.
• Labyrinth mob ntawm lub hnov hloov khoom nruab nrog: ringing nyob rau hauv lub pob ntseg (tshwm sim heev tsis tshua muaj).
• System licas: rov qab mob, mob nyob rau hauv lub caj dab.
• Common phiv: peripheral edema thiab asthenia.

Raws li koj tau pom, "Moxonidine" tshuaj yuav ua rau deterioration ntawm tus neeg mob tus mob. Yog hais tias lub sab los yog cov lus hais, ces cov tshuaj ntawm tshuaj yuav tsum tau txiav.

txhais tau tias kev sis raug zoo nrog lwm yam tshuaj

Yuav kom cov tshuaj "Moxonidine", "Moxonidine Sandoz" thiab lwm yam analogues tshuaj pab tus neeg mob thiab tsis ua rau nws ntxiv raug mob, lawv yuav tsum tau coj tsuas yog nyob rau cov tshuaj. Tom qab lub simultaneous txais tos ntawm lub cuab tam nrog rau lwm cov tshuaj yuav ua rau pliaj tshua. Yuav ua li cas raws nraim, peb yuav saib tam sim no.

Ib-lub sij hawm kev siv ntawm cov tshuaj "moxonidine" nrog rau cov tib antihypertensive agents yuav ua rau ib tug additive nyhuv.

Antidepressants (tricyclics) txo cov efficiency ntawm antihypertensive tshuaj paus kev txiav txim. Nyob rau hauv no hais txog, lawv tsis pom zoo rau siv nyob rau hauv ua ke nrog xws li ib tug tshuaj raws li moxonidine.

Saib hu rau medicament tau yooj yim exacerbate cov teebmeem ntawm cov tshuaj, tricyclic antidepressants, raws li zoo raws li ethanol, hypnotics thiab sedatives.

Lub active tshuaj yog ib tug medicament mob pesnrab attenuated pab txoj kev txawj ntse zog cov neeg uas ib txhij tau txais lorazepam.

Thaum lub sij hawm ntawm "Moxonidine" tshuaj thiab "benzodiazepine" tej zaum yuav ua ntu tshuaj kom tsaug zog derivatives ntawm lub yav tas.

Kws txawj hais tias Moxonidine yog tau los ntawm tubular secretion. Nyob rau hauv kev twb kev txuas nrog rau qhov no nws yuav tsum tsis txhob siv tshuaj uas kuj distinguished los ntawm tubular secretion.

Lub sij hawm ntawm hnub thiab lactation (cev xeeb tub thiab lactation)

Yuav lub sij hawm ntawm hnub noj tshuaj "Moxonidine-LF"? Cov lus qhia tshuaj muaj cov ntaub ntawv uas yog nruj me ntsis tshuaj thiab txaus tshawb fawb txog kev ruaj ntseg ntawm cov tshuaj xam tau tias yog thaum lub sij hawm cev xeeb tub tau ua. Uas yog vim li cas nws yog tsis pom zoo kom siv no ntawm cov neeg mob.

Peb tsis tau hais tias cov tshuaj "Moxonidine" yuav tsum tsis txhob siv thaum lub sij hawm pub niam mis. Qhov no yog vim lub fact tias nws yog tseem ceeb nrog niam cov kua mis. Yog hais tias thaum lub sij hawm lactation tshuaj tsis tau raug taw, ces mis-feeding yuav tsum tau txiav.

Nyob rau hauv tus txheej txheem ntawm cov kev tshawb fawb (experimental) nyob rau hauv cov tsiaj, nws twb pom hais tias cov medicament muaj feem xyuam rau embryotoxic.

Cov kev taw qhia nyob rau kev siv cov tshuaj

Raws li daim ntawv cov lus qhia, thaum siv cov tshuaj "Moxonidine" yuav tsum tshwj xeeb ceev faj. Tshwj xeeb tshaj yog nws kev txhawj xeeb ib tug nyias muaj nyias ib qeb ntawm cov neeg mob. Uas, peb piav qhia txog tam sim no.

Kev ceev faj thaum ua ntawv thov "Moxonidine" medicament kom raug cai nyob rau hauv cov neeg mob uas AV-blockade 1 degree. Qhov no yog vim lub fact tias cov neeg zoo li muaj yog ib tug zoo kev pheej hmoo ntawm bradycardia.

Tsis tas li ntawd tau txais cov tshuaj yuav tsum tau ua raws kev tswj ntawm ib tug kws kho mob uas muaj teebmeem coronary artery kab mob, lub raum tsis ua hauj lwm thiab tsis ruaj tsis khov angina. Qhov tseeb yog vim lub fact tias cov kev siv cov tshuaj nrog xws li kev txawv txav yog tsis txaus.

Yog hais tias koj xav mus rau suam lub simultaneous siv ntawm cov tshuaj "moxonidine" thiab beta-blockers, koj yuav tsum xub rho tus xeem chaw uasi, ib tug ob peb hnub tom qab ntawd - cov thib ob.

Rau hnub tim yog tsis muaj pov thawj hais tias siv ceev xwmphem "Moxonidine" tshuaj ua rau muaj zog cov ntshav siab. Txawm li cas los, txawm hais tias cov kws txawj cuaj kaum kom rau theem tawm cov tshuaj. Cov tshuaj yuav tsum raug txo tshaj yav dhau los ob lub lim piam.

seb cov tshuaj muaj feem xyuam rau cov muaj peev xwm tsav lub cev muaj zog thauj?

Thaum lub sij hawm lub sij hawm ntawm kev kho mob kev kho mob nrog "Moxonidine" neeg yuav tsum tau yuav tsum tau tshwj xeeb tshaj yog ceev faj thaum pib nyob rau hauv txaus ntshai ua ub no, raws li zoo raws li thaum tsav tsheb tsheb. Qhov no yog vim lub fact tias cov tshuaj yuav cuam tshuam nrog txais tos concentration thiab psychomotor tshua.

Analogs, thiab tus nqi ntawm cov tshuaj

Yuav cov tshuaj "Moxonidine" nyob rau hauv lub tsev muag tshuaj uas koj ua tau tsis muaj tshuaj. Tus nqi ntawm cov tshuaj no yog tus uas tsis muaj. Ib pob, uas muaj 14 ntsiav tshuaj koj yuav tau them txog 115-135 Lavxias teb sab rubles.

Yog hais tias peb xav ib cov tshuaj koj tsis tuaj, los yog koj cia li tsis tau mus nrhiav nws nyob rau lub tsev muag tshuaj, tom qab xa mus rau ib tug kws, lub tom kawg yog yuam ua hauj lwm kom ib tug yeeb tshuaj analogue. Cov no cov tshuaj kuv xav highlight cov nram qab no: "Fiziotenz", "Moxonidine-C3", "Moksarel", "Canon ntawm Moxonidine", "Moksoniteks", "Moksogamma", "Tenzotran" thiab thiaj on.

Siv cov nyiaj yuav tsum nruj me ntsis raws li tus kws kho mob pom zoo. Tsis tas li ntawd, ua ntej txoj kev siv cov tshuaj yuav tsum paub txog cov ntawv qhia.

Cov tshuaj "Moxonidine": xyuas ntawm cov kws kho mob thiab cov neeg mob

Raws li cov kws tshwj xeeb, cov tshuaj no yog zoo heev rau tawg. Qhov no lub tswv yim yog qhia los ntawm cov neeg mob. Txawm li cas los, ib co ntawm lawv complained hais tias tom qab noj cov ntsiav tshuaj tom qab ib tug thaum lawv qhia phiv xws li mob taub hau, qhov ncauj qhuav, nervousness thiab xeev siab. Nyob rau hauv cov ntaub ntawv no, cov kws kho mob pom zoo kom tshuaj mus rho thiab hloov nws analogue, uas yog kev ruaj ntseg rau kev kho mob.