Kev npaj "poov tshuaj tshuaj dawb"

Kev npaj "poov tshuaj tshuaj dawb" yog ib lub cuab tam uas yog npaj los pab lub tshaj ntawm poov tshuaj nyob rau hauv lub cev. Qhov no ntsev, uas yog tog twg los tsis muaj kob los yog muaj ib tug dawb cov xim, nws yuav ua tau nyob rau hauv daim ntawv ntawm ib tug hmoov, ib tug daws, thiab nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, nws kuj yog siv nyob rau hauv qhuav ntawm tshuaj xws li poov tshuaj hydroxide thiab poov tshuaj carbonate.

Uas poov tshuaj yog lub loj intracellular ion, uas ua ib tug loj luag hauj lwm nyob rau hauv kom cov kev cai ntawm ntau yam cev tsis muaj zog. Qhov no lub caij yog muab kev koom tes nyob rau hauv tus cwj pwm thiab hloov mus rau hauv nruab nrog cev innervated los ntawm lub paj impulse thaum lub sij hawm skeletal leeg contraction, nyob rau hauv kev tswj cov intracellular osmotic siab thiab ntau ntau lwm yam biochemical dab. nws kuj txo tus conductivity thiab myocardial excitability, thiab nws muaj nyob rau hauv siab koob tshuaj cheeb qhov uas cov automatism.

Tom qab kev npaj "poov tshuaj tshuaj dawb" noj kwv yees li 70% ntawm nws cov passively absorbed vim lub fact tias cov poov tshuaj concentration yog ntau dua nyob rau hauv lub lumen ntawm cov hnyuv tshaj nyob rau hauv cov ntshav. Nyob rau hauv cov nyuv thiab ileum active microcell tso tawm rau hauv lub lumen, yog nws conjugate exchanged nrog sodium, tom qab uas hais txog 10% yog tso tawm ua ke nrog lub bile.

"Poov tshuaj tshuaj dawb" Cov tshuaj - tshuaj ntau npaum

Ib tug tib koob tshuaj yuav tsum tsis txhob ntau tshaj 25-50 mEq ntawm poov tshuaj, whereas lub hnub koob tshuaj yuav ua tau siab tshaj 50-100 meq poov tshuaj. Hoob no ntawm kev kho mob thiab zaus ntawm koom haum saib xyuas ntawm cov tshuaj nyob rau hauv lub yeej. Yog hais tias tsim nyog, txhais tau tias ntawv "poov tshuaj tshuaj dawb" tso dej tshuaj thiab kev kho mob regimen nyob rau hauv txhua rooj plaub txiav txim nyias.

tshuaj cov kev sib tshuam

Yog hais tias daim ntawv tso cai simultaneous siv ntsev hloov, poov tshuaj-sparing diuretics, poov tshuaj thiab lwm yam tshuaj, muaj yog ib tug zoo kev pheej hmoo ntawm hyperkalemia.

Yog hais tias nws yog tsim nyog los tsim kom muaj xws li ib tug yeeb tshuaj mus rau ib tug cev xeeb tub poj niam, nws yog tsim nyog tias tus kws kho mob ntsuam xyuas cov kev tsim cov kev pab los ntawm nws rau leej niam thiab tus liam teeb meem rau lub fetus. Thaum pub ib tug me nyuam pub niam mis yuav tsum tau muab tso tseg ua ntej yuav siv cov khoom.

Tej kev phiv

Tej yam tshwm sim ntawm hyperkalemia feem ntau leeg tsis muaj zog, paresthesias nyob rau hauv lub sab sauv thiab sab nqua, arrhythmia, lub plawv thaiv thiab tsis txhob tsis meej pem.

Yog hais tias nws yog ib txoj kev ntawm "poov tshuaj tshuaj dawb" tshuaj sab hauv, tej zaum nws yuav ua rau xeev siab, ntuav thiab raws plab. Tsis tas li ntawd, nyob rau hauv tej rooj plaub, tej zaum yuav tshwm sim ulcerative txhab ntawm lub plab thiab cov hnyuv, feem ntau nrog los ntawm ntshav thiab perforation, thiab tom qab tsim stricture.

Tom qab tso dej thawj coj ntawm cov tshuaj tej zaum yuav tsim nyob rau hauv yuam cai ntawm lub plawv.

indications

"Poov tshuaj tshuaj dawb" yog muab rau cov tshuaj nyob rau hauv lub xub ntiag ntawm hypokalemia ntawm tej keeb kwm, nrog rau tom qab mob loj heev ntuav los yog zawv plab, nrog polyuria thiab mob raum tsis ua hauj lwm. Nws kuj yuav tshwm sim los ntawm tsawg ntawm cov ib co tshuaj, yuav tshwm sim tau thaum lub glycoside intoxication los yog tsim hypokalemic periodic tuag tes tuag taw.

Contraindications

Cov tshuaj no yog tsis qhia rau lub xub ntiag ntawm raum excretory muaj nuj nqi, nrog rau tag nrho lub plawv thaiv. nws yuav tsum tau tsis txhob muab ntaub ntawv thaum hyperkalemia, metabolic mob raws li acidosis, hyponatremia nrog hypovolemia, nyob rau hauv lub xub ntiag ntawm hnyuv kab mob uas raug nce, thiab adrenal insufficiency.

Nyob rau hauv tshuaj cov tuag koob tshuaj ntawm poov tshuaj tshuaj dawb ntawm ntau dua tshaj li 5 grams, yog tias tsim nyog, tshuaj loog thaum phais sufficiently 100-150 mg ntawm cov tshuaj. Yog hais tias cov tshuaj yog muab intravenously, thiab ceev heev, tsim hyperkalemia, uas muaj peev xwm ua rau tuag ntawm tus neeg mob. Yog li ntawd nws yog tsim nyog los paub hais tias nws muaj peev xwm loj hlob sai sai heev thiab tsis muaj kev sab nraud manifestation ntawm cov tsos mob. Nyob rau hauv cov ntaub ntawv ntawm ib tug overdose yuav tsum tau nkag mus hauv cov tshuaj ntawm sodium tshuaj dawb lus los yog intravenously, los yog IV ntawm los ntawm 300 mus rau 500 milliliters ntawm dextrose, nyob rau hauv 1000 ml ntawm cov uas muaj 10-20 units ntawm insulin.