"Dipyridamole": cov lus qhia rau kev siv. "Dipyridamole": xyuas thiab analogues

Yuav ua li cas yog cov tshuaj "Dipyridamole"? Cov lus qhia, nqe, nta, thiab indications ntawm cov nyiaj yuav tsum hais hauv qab no. Peb kuj qhia koj tias nws yog ua tau rau tau txais hais tias cov tshuaj thaum lub sij hawm cev xeeb tub, yog hais tias nws muaj tej yam analogues, tshwm sim thiab contraindications.

Muaj pes tsawg leeg, packing thiab zoo

Qhia tias qhov kev npaj ntawm cov phau ntawv qhia? "Dipyridamole" - ib tug tshuaj uas muaj ib co daim ntawv ntawm tso tawm. Cia peb xav txog lawv nyob rau hauv ntau yam:

• Dragee 0.075 thiab 0.025, lub active tshuaj ntawm daim ntawv no yog dipyridamole. Cov tshuaj no yog muag nyob rau hauv hnab yas pob khoom ntawm 100 tej daim.
• "Dipyridamole" - ntsiav tshuaj ntawm 0,075, 0,005 thiab 0,025 g Coated, lawv kuj muaj cov active tshuaj xws li dipyridamole. Nrog kev xav txog cov koom haum pab cov ntsiab, lub tom kawg muaj xws li calcium stearate, lactose monohydrate thiab cov hmoov txhuv nplej. Tshuaj yog muag nyob rau hauv sawv hlwv 120 los yog 40 daim, uas yog muab tso rau hauv ib pawg ntawm cov duab los qhia.
• Ib tug tov rau kev txhaj tshuaj. Qhov no daim ntawv muaj xws li ib tug zoo xws li cov active tshuaj. 0.5% tov yog muag nyob rau hauv vials ntawm 2 ml.

pharmacodynamics

Yuav ua li cas yog cov khoom xam tau tias yog tshuaj? Yuav ua li cas yog nws txuas cov lus qhia rau kev siv? "Dipyridamole" - ib tug tshuaj uas muaj ib tug vasodilating nyhuv. Tej kev txiav txim nws muaj tsuas yog nyob rau coronary hlab ntsha.

Cov txais ntau npaum ntawm medicament cheeb adhesion ntawm platelets tsub kom lub ntshav txaus tus nqi, pab txoj kev thiab renders angioprotective kev txiav txim. Ntxiv mus, qhov kev kawm txhais tau tias yeej txhawb collateral ncig nyob rau hauv cov hlab ntsha ntawm lub plawv.

Peb tsis tau hais tias cov tshuaj normalizes venous outflow. Yog li ntawd, nws tsis tu ncua tsawg ho thiaj li txoj kev pheej hmoo ntawm thrombosis, tshwj xeeb tshaj yog nyob rau hauv lub postoperative lub sij hawm.

hauv paus ntsiab lus ntawm cov lag luam

Yuav ua li cas lwm yam yeeb tshuaj muaj zog "Dipyridamole"? Phau ntawv hais tias nws txhais tau hais zoo txo lub suab nrov ntawm cerebral hlab ntsha. Nyob rau hauv no hais txog, nws yog heev nquag siv rau nraum ischemic tawm tsam. Ntxiv mus, nws suav hais tias yog tshuaj pab markedly placental ncig. Qhov no feature tso cai rau koj los mus tiv thaiv me nyuam hauv plab hypoxia.

Yuav ua li cas yog lub mechanism ntawm qhov kev txiav txim ntawm cov tshuaj? Cov ntaub ntawv muaj cov lus qhia rau kev siv? "Dipyridamole" tsub kom cov kev ua ntawm adenosine thiab thiaj li nws tuav ntaub so ntswg. Hais tias tej yam khoom uas muaj feem xyuam rau vascular nqaij los thaiv cov hlab norepinephrine tso tawm, uas, nyob rau hauv qhov tseeb, ua rau lawv contraction, ua ntshav siab thiab mauj vascular kuj.

Tsis tas li ntawd nws yuav tsum tau muab sau tseg hais tias raws li ib tug tshwm sim ntawm thaiv cov hlab qhov phosphodiesterase txo qhov kev tso tawm ntawm activators aggregation ntawm platelets. Qhov no feature tiv thaiv lawv los ntawm so. Tus thawj nyob rau hauv platelet adhesiveness tiv thaiv cov ntshav txhaws nyob rau hauv cov hlab ntsha.

Tshuaj "Dipyridamole", tus nqi ntawm uas yog qhia hauv qab no, raws li cov antiplatelet agents yog feem ntau siv nyob rau hauv ua ke nrog nrog acetylsalicylic acid.

tshuaj

Absorbed xam tau tias yog ib tug txhais tau tias theej sai sai. Nws siab tshaj plaws concentration yog mus txog txog 60 feeb tom qab thawj coj.

Lub tsub zuj zuj ntawm cov active tshuaj yog nqa tawm nyob rau hauv myocardiocytes. Drug undergoes metabolism hauv lub siab. Nyob rau hauv cov ntaub ntawv ntawm ua txhaum ntawm lub cev uas ua hauj lwm tau txuam nrog.

indications

Medicament "Dipyridamole" tshuaj nyob rau hauv cov nram no cov kab mob:

• coronary insufficiency mob xwm;
• rau kev tiv thaiv occlusion ntawm shunts thiab stents;
• angina;
• myocardial infarction (tsis tsuas nyob rau hauv lub mob theem);
• venous thiab arterial thrombosis;
• ischemic stroke;
• kev tiv thaiv ntawm thromboembolism, tshwj xeeb tshaj yog tom qab phais tiv thaiv nyob rau hauv lub plawv;
• placental insufficiency;
• plawv encephalopathy;
• atherosclerosis ntawm ob txhais ceg;
• microcirculatory mob ntawm tej keeb kwm;
• glomerulonephritis;
• DIC nyob rau hauv sepsis nyob rau hauv ib tug me nyuam thiab toxicosis.

Contraindications

Raws li cov lus qhia ntawm cov nyiaj yuav siv tsis tau yog hais tias tus nram qab no hloov:

• hypotension ;
• tsis ruaj tsis khov angina;
• mob myocardial infarction;
• npau taws me ntsis;
• mob loj heev arrhythmias;
• decompensated lub plawv tsis ua hauj lwm;
• siab ua hauj lwm;
• hemorrhagic diathesis;
• plab ulcers, tshwj xeeb tshaj yog nrog ib tug ib txwm mus los ntshav.

Koj yuav tsum tau hais tias cov tshuaj no yog tshuaj nrog ceev faj rau cov me nyuam nyob rau hauv 12 lub xyoos ntawm hnub nyoog thiab lactation. Tsis tas li ntawd, nws yog tsis yooj yim sua mus thov tus neeg saib xyuas intravenously thaum lub sij hawm cev qhuav dej.

Cov lus qhia rau kev siv

"Dipyridamole" - anti-thrombotic tshuaj uas yuav tsum tau muab los ntawm cov chaw tus kws kho mob.

Feem ntau, ntsiav tshuaj thiab tshuaj noj ntawm ncauj 60 feeb ua ntej noj mov, ib khob ntawm cov dej. Nyob rau hauv thiaj li yuav txo cov khaus ntxim rau cov pais plab mucosa cov tshuaj yuav tsum tau muab ntxuav cia nrog mis nyuj sov.

Ntau npaum thiab tus qauv ntawm kev siv ntawm cov tshuaj yuav tsum tau ntsia xwb los ntawm ib tug kws kho mob nyob ntawm seb tus neeg mob lub hnub nyoog, nyeem ntawv thiab nws cov xeev kev kho mob.

Rau kev tiv thaiv ntawm thrombosis muab 75 mg ntawm medicament 6 lub sij hawm ib hnub twg (nyiaj pab ntau tshaj txhua hnub koob tshuaj - 300-450 mg).

Thaum coronary insufficiency siv 25-50 mg ntawm cov tshuaj peb zaug ib hnub twg. Qhov siab tshaj plaws tshuaj thaum lub xeev no - txog 150-200 mg.

Nyob rau hauv thiaj li yuav tiv thaiv kom txhob txhaws ntawm lub stent graft thiab tus neeg mob yog muab 50 mg ntawm yeeb tshuaj (plaub zaug ib hnub twg) ua ke nrog acetylsalicylic acid. Lub medicament yog siv ua ntej lub lag luam, raws li tau zoo raws li thaum lub sij hawm lub lim tiam tom qab.

Thaum occlusive vascular cov kab mob ntawm lub sab nqua yog pom zoo kom noj 75 mg ntawm cov tshuaj peb zaug ib hnub twg.

Lub sij hawm ntau npaum ntawm cov tshuaj rau cov me nyuam nyob rau hauv lawv qhov ceeb thawj (5-10 mg ib kg).

Raws li cov lus qhia, thaum lub sij hawm kev kho mob yog tsim nyog los txwv cov kev noj tshuaj yej thiab kas fes, raws li lawv muaj peev xwm tsis muaj zog cov nyhuv ntawm cov tshuaj.

overdose

Thaum uas siv cov siab koob tshuaj ntawm cov tshuaj nram qab no cov tsos mob tej zaum yuav tshwm sim nyob rau hauv ib tug neeg mob: txo cov ntshav siab, kiv taub hau, muaj zog lub plawv dhia thiab ntshav. Nyob rau hauv cov ntaub ntawv no, tsis txhob tshuaj thiab tham ib tug kws kho mob.

phiv tshua

Raws li cov lus teb ntawm cov neeg mob, nyob rau hauv tej rooj plaub, lub txais tos ntawm cov nyiaj yuav ua rau cov nram qab no tshwm sim tsis zoo:

• kev tsis haum tshuaj;
• lub plawv palpitations;
• txos cov ntshav siab (tshwj xeeb yog thaum muab intravenously);
• thrombocytopenia;
• mob taub hau;
• dyspeptic mob;
• suab nrov nyob rau hauv lub taub hau;
• ntawm lub ntsej muag yaug kais dej;
• tachycardia;
• nce los ntshav los yog los ntshav.

tshuaj cov kev sib tshuam

Antiplatelet nyhuv uas cov tshuaj no yog kho kom zoo los ntawm simultaneous thawj coj nrog acetylsalicylic acid, tetracycline, penicillin, cephalosporin, indirect anticoagulants thiab nicotinic acid.

Nws yuav tsum tau muab sau tseg tias indirect anticoagulants, thrombolytics thiab heparin yuav ua rau kom cov ntxim yuav zoo siv ntawm los ntshav teeb meem.

Peb tsis tau hais tias caffeine thiab xanthine tshuaj txo lub vasodilating thiab anti-thrombotic los ntawm cov nyiaj, thiab antacids txo nws haum thiab txo lub concentration hauv cov ntshav.

Nrog kev xav txog cov piav kev npaj, nws yuav tsub kom lub los ntawm antihypertensive tshuaj.

Kuv yuav siv cov tshuaj "Dipyridamole" thaum lub sij hawm cev xeeb tub?

Kws txawj hais tias thaum noj nyob rau hauv saib xyuas cov nyiaj nyob rau hauv cev xeeb tub cov poj niam tsim teeb meem. On qhov tsis tooj, cov tshuaj "Dipyridamole" thaum lub sij hawm cev xeeb tub yog feem ntau tus kws kho thaum muaj ib tug kev hem thawj ntawm nchuav menyuam ntawm ib tug me nyuam los yog placental insufficiency.

Nqi thiab analogues

Cov tshuaj yuav tau muab hloov "Dipyridamole"? Analogs ntawm cov nyiaj uas teev tseg hauv qab no. Cov no muaj xws li nram qab no tshuaj: "Parsedil", "Kurantil", "Padikor", "Antistenokardin", "Trankokord", "angina", "persantin", "Dipyridamole-Verein". Tag nrho cov ntawm cov tshuaj muaj tib lub active ingredient. Txawm li cas los, tej zaum lawv yuav muaj nyias kev phiv thiab contraindications. Nyob rau hauv no kev twb kev txuas, nws yog pom zoo kom siv cov nyiaj no tsuas yog tom qab kev noj kev haus koj tus kws kho mob.

Yuav ua li cas npaum li cas yog ib tug yeeb tshuaj "Dipyridamole"? Nws nqi yog hom twg los ntawm 380-420 rubles (nyob ntawm seb tus nqi thiab daim ntawv ntawm cov tshuaj tso tawm).

Xyuas

Feem ntau cov feem ntau, koj lub tswv yim hais txog qhov cuab tam yog tshuav nyob rau hauv cov neeg mob rau leej twg nws tau muab rau tus tiv thaiv thiab kev kho mob ntawm ntxov ntxov placental laus, raws li zoo raws li placental insufficiency.

Nws yuav tsum tau muab sau tseg uas cev xeeb tub cov poj niam raug kev txom nyem xws li ib tug yeeb tshuaj yog zoo nkauj zoo. Tsuas yog ib ob peb ntawm cov ncaj ncees txiv neej pw muaj kev phiv tshuaj nyob rau hauv daim ntawv ntawm ib tug txo nyob rau hauv cov ntshav siab thiab kiv taub hau.