Cromoglicic acid. Hauj lwm, indications, contraindications

Yuav ua li cas yog kromoglitsievoy acid? Qhov no koj yuav kawm tau los ntawm cov ntaub ntawv yog muab los ntawm tsab xov xwm. Peb kuj qhia koj hais txog tej uas cov tshuaj muaj cov hais tias tshuaj thiab hais tias nws sawv cev rau.

tso tawm daim ntawv no, ib tug piav qhia ntawm

Cromoglicic acid yog tsim raws li ib ib aerosol rau inhalation, qhov ntswg tshuaj tsuag, qhov muag dauv thiab qhov ntswg tshuaj tsuag. Tsis tas li ntawd qhov cuab tam yuav yuav nyob rau hauv daim ntawv ntawm ib tug ntshiab tov thiab tsiav tshuaj nrog ib tug hmoov, npaj rau nqus tau pa.

Lub hauv paus ntsiab lus ntawm cov lag luam ntawm ib tug medicament

Cromoglicic acid, tus nqi ntawm uas yog qhia hauv qab no, stabilizes mast cell week, raws li zoo raws li lawv pellets. Qhov no yog vim lub blockade ntawm calcium nkag mus rau hauv lub hlwb.

Nws yuav tsum raug sau tseg hais tias qhov no neeg sawv cev cheeb qhov kev tso tawm ntawm kev tsis haum tshuaj kho xws li leukotrienes, histamine, thiab lwm yam SG2, los ntawm ntau hlwb, uas yog nyob rau hauv lub mucosa ntawm lub lumen ntawm lub bronchi thiab bronchial tsob ntoo. Nyob rau hauv tas li ntawd, qhov no tshuaj yuav pab tau suppress lub tsiv teb tsaws ntawm monocytes thiab qe.

zog

Cromoglicic acid exhibits lub nram qab no cov khoom:

• Heev zoo rau kev tiv thaiv ntawm tam sim ntawd yam tsis haum tshuaj nyob rau hauv tub ntxhais hluas, uas muaj tseem tsis tau nyob irreversible mob hloov nyob rau hauv lub ntsws. Nws yuav tsum tau muab sau tseg tias hais tias yam khoom uas yog tsis tau tsim eliminates bronchospasm.
• Teev daim nyias nyias-stabilizing nyhuv. Cov txheej txheem rau inhibiting pulmonary teb kho kom haum xeeb yuav pab nyob rau hauv kev tiv thaiv cov kev loj hlob ntawm thaum ntxov thiab lig theem asthmatic teb (nrog rau lo lus teb rau lub cev thiab lwm yam stimuli).
• Ruaj nyhuv ntawm kev siv ntawm cov tshuaj yog tiav tom qab 2-4 lub lis piam. Nyhuv ntawm cov tshuaj tom qab ib tug tib thawj coj muaj rau 5 teev.
• Pom tau ntawm kev kho mob nyob rau hauv kev tsis haum cov kab mob ntawm nrig txog kev pom cov kabmob no tshwm sim tom qab ib tug ob peb hnub los lub lis piam.

• Heev siv ntawm cov tshuaj thiaj li zaus kev tawm tsam ntawm bronchial hawb pob, thiab zoo heev tswj lawv cov hoob kawm, thiaj li qhov yuav tsum tau rau kev noj corticosteroids thiab bronchodilators.

kinetics

Cromoglicic acid absorbed los ntawm cov pa ib ntsuj av tau nyob rau hauv ib tug npaum li ntawm 10%, thiab tom qab nqus tau pa ntawm medicament hmoov thiab tshuaj - 5-15% thiab 8% feem.

Suction los ntawm ua pa txheej week txo thaum tus nqi ntawm cov pa. Qhov siab tshaj plaws concentration ntawm cov tshuaj yeeb dej caw yog tiav tom qab ¼ teev.

Qhov cuab yeej no yog tsis metabolized. Nws ib nrab-lub neej ntawm 45-90 feeb. Tso zis los ntawm cov hnyuv thiab ob lub raum nyob rau hauv hais txog sib npaug zos proportions, raws li zoo raws li los ntawm lub ntsws.

Intranasal thawj coj mus rau hauv cov hlab ntsha tau txais txog 7% ntawm lub formulation. Nrog ntshav cov nqaijrog nws uake rau 65%. Thaum zoo li no cuab tam yog tsis metabolized thiab tas nyob hauv cov kua tsib thiab ob lub raum nyob rau hauv unchanged daim ntawv nyob rau hauv ib nrab teev. Part ntawm lub active tshuaj yog nqos tsis tau haum thiab yog faib los ntawm cov hnyuv ib ntsuj av.

zaj lus tim khawv

Ncos rau ob lub qhov muag Antiallergic muab nrog tsis haum conjunctivitis, allergic keratitis, keratoconjunctivitis, qhuav qhov muag syndrome, lim, nkees lub qhov muag mucosa voos nrig txog kev pom cov kabmob los tsis haum.

Nws yuav tsum raug sau tseg hais tias qhov no cuab tam yog siv rau kev tiv thaiv ntawm bronchial hawb pob, bronchospasm thiab ntev bronchitis nrog Bos syndrome.

Cov tshuaj yog nyob rau hauv daim ntawv ntawm qhov ntswg agents pom zoo rau hay fever thiab tsis haum txhaws ntswg.

Contraindications

Saib cov tshuaj yog tshuaj rau:

• npau taws me ntsis;
• cev xeeb tub (thawj peb lub hlis rau nqus tau pa);
• nyob rau hauv cov me nyuam (txog li ob lub xyoo - nyob rau hauv daim ntawv ntawm cov hmoov thiab tsiav tshuaj rau nqus tau pa tshuaj, uas muaj hnub nyoog 5 - nyob rau hauv daim ntawv ntawm ib tug aerosol rau nqus tau pa thiab intranasal thawj coj);
• noj niam mis (rau intranasal thawj coj).

Kromoglitsievoy acid: kev qhia

Nqus tau pa tshuaj rau nqus tau pa yuav tsum tau ua siv spinhalera 4 lub sij hawm ib hnub twg ntawm cov Team sib ntawm 3-6 teev (20 mg).

Taub txua tshuaj nqus tau pa aerosol muab 1 koob tshuaj (1 mg) plaub zaug ib hnub twg.

Tshuaj rau nqus tau pa siv ib tug tshuaj txau los ntawm txhais tau tias (20 mg) plaub zaug ib hnub twg. Ua ntej siv lub raj mis yog shaken kom zoo thiab khaws cia nyob rau hauv ib tug upright txoj hauj lwm.

Qhov ntswg dauv los siv rau cov neeg laus nyob rau hauv txhua nostril 3-4 dauv nyob rau hauv 4-6 lub sij hawm, thiab cov me nyuam los ntawm 6 xyoo - txhua 6 lub sij hawm rau 1-2 ncos. Tom qab cov tsos ntawm cov kho nyhuv ntawm lub luv ntawm koob tshuaj ntawm cov tshuaj tej zaum yuav maj mam nce.

Qhov ntswg tshuaj tsuag thov 1 koob tshuaj nyob rau hauv txhua qhov ntswg kawg 4-6 lub sij hawm ib hnub twg. Hoob no ntawm kev kho mob yog 4 lub lis piam. Abolition ntawm cov tshuaj yuav tsum tau nqa tawm maj tshaj ib lub lim tiam.

Qhov muag dauv (e.g., "Sodium cromoglycate") siv 1-2 dauv nyob rau hauv txhua lub qhov muag plaub zaug ib hnub twg lub cev nrog ib tug caij nyoog ntawm 4-6 teev. Yog hais tias tsim nyog, tus xov tooj nce mus instillation ntawm 6-8 ncos.

phiv

Cov kev kawm yuav ua rau:

• kiv taub hau, xeev siab, nosebleeds;
• voos thiab dryness nyob rau hauv lub caj pas, mob taub hau, qhov ncauj qhuav, urinary tuav;
• ua pa voos, txhaws ntswg, hnoos, hlawv ntawm lub qhov muag, impaired raum muaj nuj nqi, muaj zog secretion ntawm tej kua ntswg;
• daim tawv nqaij sawv pob, conjunctival edema, qhuav qhov muag, tsis kaj siab saj nov ntawm nqaij tawv, txawv teb chaws lub cev nov ntawm nqaij tawv, barley, lacrimation;
• anaphylaxis (xws li teeb meem nyob rau nqos, khaus tawv nqaij, qhia crowing, ua xua, o ntawm ob daim di ncauj, lub ntsej muag thiab tawv muag daj, tej ntshav siab, ua tsis taus pa).

Txhais thiab tus nqi ntawm cov tshuaj

Nyob rau hauv dab tsi lag luam lub npe muag acid kromoglitsievoy? Qhov no "Ditek", "cromolyn sodium," "Ifiral", "Intal", "kromogeksal", "Kromogen Easi-pa", "Nalkrom", "Kromogen", "Kromoglin", "Kromosol", "Cromolyn", "Kropoz "" Lekrolin "," Kuzikrom "," Stadaglitsin "," Hi-chrome ".

Tus nqi ntawm cov txhais tau tias tej zaum yuav sib txawv, nyob ntawm seb lub chaw tsim tshuaj paus, rau hauv daim ntawv ntawm cov tshuaj thiab lub tsev muag tshuaj network. Txawm li cas los, cov nqi nruab nrab kromoglitsievoy acid yog 100-250 rubles.