Xyuas: "Flucostat" qhov ncauj tawm. "Flucostat" qhov ncauj tawm - zoo li noj

Nyob rau hauv no tsab xov xwm, peb txiav txim siab los tham txog ib tug kab mob zoo li Candidiasis. Nyob rau hauv tas li ntawd, koj cov xim yuav tsum tau nthuav tawm mus rau ib tug tshuaj uas hlub ib tug kab mob, thiab kev txheeb xyuas.

"Flucostat" qhov ncauj tawm

Qhov ncauj tawm - yog ib tug ncaj ntau tus kab mob nyob rau hauv uas cov poov xab thiab ntau pathogenic fungi ntawm lub genus Candida muaj feem xyuam rau lub integument thiab viscera. Raws li ib tug txoj cai, Candidiasis kab mob tshwm sim yog hais tias lub cev yog zoo heev tsis muaj zog txaus.

Ntsiav tshuaj los ntawm cov poov xab "Flucostat" ntau heev kws cov kws kho mob rau cov kev kho mob ntawm tus kab mob no. Yog vim li cas qhia cov tshuaj yog nrov li thiab coob leej ntau tus? Lo lus teb rau ib lo lus nug, koj yuav nrhiav tau hauv qab no.

Muaj pes tsawg leeg txhais tau tias

qhov ncauj tawm "Flucostat" yog pom zoo kom pib kho mob tsuas yog tom qab kev noj kev haus ib tug kws kho mob. Tom qab cov tshuaj muaj ib co mob tshwm sim thiab contraindications.

Feem ntau, cov medicament yog manufactured nyob rau hauv daim ntawv ntawm cov tshuaj opaque teeb liab los yog xim av xim. Lawv cov ntsiab lus yog ib tug dawb los yog me ntsis off-dawb hmoov. Nws muaj fluconazole (150 los yog 50 mg), thiab koom haum pab xws li pob kws starch, colloidal silicon dioxide, magnesium stearate, lactose thiab sodium lauryl sulphate.

Tom qab tau txais qhov no txhais tau tus neeg mob yuav luag ib txwm tshuav nws tsuas zoo lub tswv yim. "Flucostat" qhov ncauj tawm lub sij hawm ntev thiab muaj lawm siv tau ntse. Ua ke, cia peb xav txog nws txoj ntsiab cai ntawm cov lag luam.

pharmacodynamics

Raws li hais saum toj no, tus thawj xib fwb active ingredient ntawm lub medicament yog fluconazole. Nws yog ib hoob ntawm triazole noj cov tshuaj mas siv, uas muaj sufficiently hwj chim xim inhibitor ntawm sterol synthesis nyob rau hauv lub fungal hlwb.

Raws li paub, Fluconazole yog tshwj xeeb yog active tiv thaiv opportunistic fungal kab mob, nrog rau cov tshwm sim los ntawm Cryptococcus neoformans, Candida spp., Trichophyton spp. thiab Microsporum spp. Nyob rau hauv tas li ntawd, cov tshuaj no yog feem ntau kws kho rau kis txhab xws li Coccidioides immitis, Blastomyces dermatitidis, thiab Histoplasma capsulatum.

txhais tau tias ntawm cov kev taw qhia

Txhais tau hais tias "Flucostat" qhov ncauj tawm (xws li kev noj tshuaj, xav txog ib tug me ntsis hauv qab no) yog zoo yaim thiab sai sai absorbed. Nws bioavailability yog hais txog 90%. Nws yuav tsum tau muab sau tseg tias cov simultaneous kom tsawg ntawm cov khoom noj khoom haus tsis muaj kev cuam tshuam haum ntawm cov tshuaj. Cov tshuaj concentration hauv cov ntshav ntshav yog ncaj qha xwm yeem mus rau koob tshuaj.

Yog vim li cas xws li ib tug yeeb tshuaj mus rau ib tug ntau dua degree yog zoo tswv yim? "Flucostat" los ntawm poov pab tau tshem ntawm tag nrho cov tsos mob thiab restore li qub xeev los ntawm cov 4-5 hnub tom qab pib ntawm kev kho mob (thaum noj thawj tsiav tshuaj ib hnub twg). Yog hais tias tus neeg mob yog siv ib tug loading koob, 2 lub sij hawm ntau tshaj qhov ib hnub pheej, lub zoo kawg li cov nyhuv yog tiav rau lub 2nd hnub.

faib los ntawm cov nyiaj

Fluconazole, uas yog ib feem ntawm cov tshuaj tom qab haus tam sim ntawd penetrates thiab yog absorbed rau hauv tag nrho cov kua (lom) kab mob. Lub concentration ntawm cov tshuaj yeeb dej caw nyob rau hauv cov qaub ncaug thiab cov hnoos yog zoo ib yam li ntshav ntau. Cov neeg uas muaj cov kab mob xws li fungal meningitis, haum ntawm fluconazole nyob rau hauv lub hlwb txha nqaj qaum kua yog yuav luag 80%. Nyob rau hauv lub dermis, epidermis, hws thiab cov stratum corneum tiav kuj muaj concentration ntawm no neeg sawv cev uas ntau tshaj cov ntshiab.

Tshem ntawm cov tshuaj

Lub sij hawm ntawm feem ntawm cov tshuaj yog kwv yees li 30 teev. Yeej fluconazole nws nyob rau hauv lub cev los ntawm ob lub raum. Yog li, yuav luag 80% ntawm lub xeem koob tshuaj ntawm cov tshuaj nyob rau hauv cov zis nyob rau hauv ib tug unmodified daim ntawv.

Yuav ua li cas npaum li cas yog "Flucostat" qhov ncauj tawm?

Nws yuav tsum tau muab sau tseg hais tias qhov no tshuaj yog muag nyob rau hauv yuav luag tag nrho cov khw muag tshuaj chains. Tom qab tag nrho, nws tsuas yog ib tug txhais tau tias ntawm zoo tswv yim. "Flucostat" ua los ntawm poov tshuaj ntawm 150 thiab 50 mg. Lub thawv yuav tsum tau nyob raws li ib tug sawv hlwv nrog ib ntsiav tshuaj, thiab nrog 2 thiab 7. Thaum lub sij hawm ib tug loading koob tshuaj ntawm cov tshuaj (1 capsule - 150mg), koj yuav tau them txog 200 Lavxias teb sab rubles.

qhov ncauj tawm kev kho mob

Feem ntau cov feem ntau, cov kws kho mob muab rau lawv cov neeg mob tshuaj "Flucostat" qhov ncauj tawm. Yuav ua li cas tau noj cov tshuaj?

Qhov zoo ntawm no txoj kev yuav tsum muaj xws li txhais tau tias ntawm nws daim ntawv thov. Tom qab tag nrho, nws tsis yog siv topically thiab hais lus, uas yog sab hauv. Yog li, poov zoo li pathogens yuav raug rhuav tshem tsis tau tsuas yog nyob rau hauv qhov chaw ntawm lub qog ua kua week (paum, qhov ncauj, thiab lwm yam), Tab sis kuj thoob plaws hauv lub cev. Nyob rau hauv no hais txog, cov kev siv ntawm "Flucostat" qhov ncauj tawm los txo cov kev pheej hmoo ntawm kev rov muaj dua.

Peb yuav tsis quav ntsej qhov tseeb hais tias lub cev muaj ntawm lub qog ua kua tsis raug kev txom nyem los ntawm kev siv ntawm cov tshuaj no. Tseeb, txoj kev loj hlob ntawm kab lig rau tus kab mob yog tsis inhibited by lub cuab tam. Vim li no cov fact nyob rau hauv lub neej yav tom ntej tus neeg tsis tshwm sim dysbiosis.

Lub caij ntawm txoj kev kho nrog "Flucostat" nyob rau hauv tus duab thiab raws li ntawm tus kab mob manifestations. Thaum Candidiasis nruab nrab thiab lub teeb heev txaus ib koob tshuaj medicament (1 capsule - 150 g). Yog hais tias xws li ib tug kab mob tshwm sim nyob rau hauv kev mob loj daim ntawv, cov tshuaj yuav tsum tau siv ob zaug (thaum xub thawj capsule). Tus thawj lub sij hawm - nyob rau hauv thawj hnub, lub thib ob - nyob rau hauv lub thib plaub. Nrog mob relapsing daim ntawv ntawm tus kab mob, cov kws kho mob pom zoo kom siv peb cov ntsiav tshuaj (1, 4 thiab 7 hnub).

Thaum paum Candidiasis, raws li zoo raws li lwm yam kab mob uas kis tau thaum sib deev, yuav tsum tau ib tug thaum uas tig mus kev kho mob ntawm tag nrho cov kev sib deev nrog ib tug neeg. Txhua yam ntawm lawv yuav tsum tau txais cov thawj capsule formulation.

Nyob rau hauv tej rooj plaub, tus kws kho mob yuav muab tshuaj rau cov qauv ntawm cov "Flucostat" cov tshuaj rau rau lub hlis (ib ntsiav tshuaj ib zaug ib lub lim tiam).

Dosing nrog rau lwm cov txhab

Raws li hais saum toj no, cov tshuaj no yuav siv tau tsis tsuas mus rau kho paum poov xab kab mob, tab sis kuj rau kev kho mob ntawm lwm qhov txhab.

• Thaum mycosis ntawm daim tawv nqaij, xws li Tinea pedis thiab puab tais. Cov pom zoo koob tshuaj - 150 mg 1 lub sij hawm rau ib lub lim tiam los yog 50 mg 1 lub sij hawm ib hnub. Nyob rau hauv zoo tib yam tus neeg mob, lub caij ntawm kev kho mob yog hais txog 14-28 hnub (mycosis nres - 6 lub lim tiam).
• Thaum pityriasis versicolor. Cov tshuaj yuav tsum 300 mg 1 lub sij hawm rau ib lub lim tiam rau 14 hnub. Ib txhia neeg yuav tsum tau thiab lub thib peb koob tshuaj, txawm hais tias nyob rau hauv feem ntau yog txaus, thiab muaj ib zaug xwb koob tshuaj ntawm cov nyiaj nyob rau hauv tus nqi ntawm 300-400 milligrams. Raws li ib tug lwm txoj regimen Tinea versicolor yuav pab raws li cov tshuaj "Flucostat" los ntawm 50 milligrams ib hnub twg rau 14-28 hnub.

Contraindications

Tam sim no koj paub uas yuav tsum tau coj los ntawm cov poov xab. "Flucostat", tus nqi ntawm uas tau raug nthuav saum toj no, nws muaj nws contraindications rau siv. Cov no muaj xws li muaj zog rhiab heev, intolerance txhais tau tias ntawm Cheebtsam, xws li lactose thiab azole tebchaw. Nyob rau hauv tas li ntawd, cov tshuaj no yog tsis pom zoo rau cov me nyuam nyob rau hauv 3 xyoos, nrog ib tug tsis muaj peev xwm lactase thiab malabsorption syndrome glucose-galactose.

Yog hais tias koj siv lwm yam tshuaj, koj yuav tsum nco ntsoov nrog koj tus kws kho mob hais txog "Flucostat" muaj peev xwm tau txais cov tshuaj. Los ntawm txoj kev, cov tshuaj no muaj ib tug high kev ua si thiab kev sis raug zoo nrog ntau hom kws ceev dua.

Thaum lub sij hawm uas cev xeeb tub thiab lactation

Kev siv lub tshuaj "Flucostat" thaum nqa ib tug me nyuam muaj peev xwm tsuas ua tau mob hnyav thiab lub neej-hem tus neeg mob, tus niam. Vim hais tias fluconazole yog tso tawm nrog rau mis mis nyuj nyob rau hauv tib ntau raws li nyob rau hauv cov ntshav, nyob rau hauv lub sij hawm ntawm lactation coj nws yog tsis pom zoo.

phiv

Raws li cov kev tshuaj, cov tshuaj no kuj muaj tshwm sim.

• Cns phiv tshwm sim mob taub hau, kiv taub hau, thiab heev tsis tshua muaj - qaug dab peg.
• Los ntawm cov mob huam tej zaum yuav muaj kev xeev siab, kev hloov nyob rau hauv saj, flatulence, mob plab, ntuav thiab raws plab. Heev tsawg mob nyob rau hauv lub siab (e.g., kab mob siab, jaundice, hyperbilirubinemia, gepatonekroz etc.).
• Feem ntau yeej tsis los ntawm lub hematopoietic system ntawm cov neeg mob qhia leukopenia, agranulocytosis thiab thrombocytopenia.
• Cardio-leeg tshav system tachycardia zaum yuav tshwm sim.
• Heev tsawg sab metabolism manifest hypercholesterolemia, hypertriglyceridemia, thiab hypokalemia.

Nyob rau hauv tas li ntawd, txais tos "Flucostat" tshuaj yuav ua kom ua xua (e.g., daim tawv nqaij ua pob liab vog, malignant exudative erythema, tshuaj lom epidermal necrolysis , etc.).