"VFS": cov lus qhia rau kev siv. Analogs, xyuas thiab contraindications "VFS"

"VFS" Ntsiav tshuaj yog cov thawj chav kawm ntawv pab pawg neeg ntawm cov neeg ua hauj antiarrhythmic. Ib tug yeeb tshuaj muaj peev xwm ntawm thaiv cov hlab sodium raws nyob rau hauv daim nyias nyias ntawm cardiomyocytes. Nws provokes tseg intraventricular thiab atrioventricular conduction shortens haumxeeb thiab zoo refractory sij hawm nyob rau hauv lub atria, nras ceg thaiv, AV-ntawm thiab Purkinje fibers. Txhais tau hais tias tsis muaj cov nyhuv rau lub duration ntawm lub QT-luv, zaus ntawm cov lus. Nyob rau hauv lub qhaj ntawv ntawm thawj zaug ces ntawm txaus los khi mob muaj nuj nqi, tshuaj "VFS" (phau ntawv qhia no muaj cov ntaub ntawv xws li) twb tsis muaj ntxim rau cov myocardial contractility. Nws tsis cuam tshuam rau conductivity ntawm lub atrioventricular ntawm anterograde kev taw qhia. Tus neeg saib xyuas muaj tsis muaj kev phiv hypotensive nyhuv. Nyob rau hauv kev xyaum nws yog tsis cim inotropic cawv. Thaum tau txais cov tshuaj tsis inhibited nyob rau hauv lub qhov ntswg ntawm automaticity. Nws muaj antispasmodic, lub zos ua kom loog, thiab muaj mob loj tsawv anticholinergic txiav txim muaj tsis muaj kev soj ntsuam tseem ceeb degree. Nws muaj me ntsis koronarorasshiryayuschee, sedative zog. Cov nyhuv ntawm qhov ncauj cim plaub caug los yog rau caum feeb. Nws nce mus txog ntau tshaj plaws ua si tom qab 80 feeb. Lub caij kho txiav txim - los ntawm 8 teev.

Tshuaj nyob rau hauv kev mob

Lub bioavailability ntawm kwv yees li 40%. Cov tshuaj no yog metabolized nyob rau hauv daim siab thiab muaj peev xwm mus txeem lub BBB. Feem ntawm cov tshuaj no tshwm sim nyob rau hauv cov zis. Thaum ua txhaum ntawm lub raum kev ua si lub sij hawm ntawm feem yog nce los ntawm 2-3 lub sij hawm.

Yuav ua li cas txhais tau tias "VFS" indications rau siv?

Cov tshuaj no yog qhia rau ventricular thiab supraventricular extrasystoles, paroxysmal tachycardia thiab hom (tsis muaj txhab nyob rau hauv lub plawv ntawm ib tug organic xwm thiab syndrome WPW), atrial Flutter thiab atrial paroxysms.

dosing regimen

Kev npaj "VFS" phau ntawv qhia kom ib koob tshuaj - 25 mg 1 lub sij hawm rau ib 8 teev. Nyob rau hauv lub qhaj ntawv ntawm express kho tshwm sim medicament coj txhua 6 teev. Nyob rau hauv tej rooj plaub tso cai rau sawv ob zaug ib koob tshuaj (50 mg). Lub sij hawm luv nyob rau hauv cov ntaub ntawv no yog 6-8 teev.

Lub hnub lub siab tshaj plaws pub tsis muaj ntau tshaj li 300 mg. Lub caij ntawm txoj kev kho thiab expediency kho Circuit Court tau txais lub teeb tshwj xeeb. Tshuaj haus dej tom qab ib tug noj mov. Pulverize los yog zuaj lub cuab tam yog tsis tso cai.

Medicament "VFS": phiv

Raws li tus kws kho mob tshuaj tshuaj zam los ntawm cov neeg mob ntawm tag nrho cov muaj hnub nyoog yog zoo txaus. Txawm li cas los, muaj ib tug tau ntawm phiv los rau lub hauv paus ntawm kev siv yeeb tshuaj kho "VFS". Sab los tej zaum yuav yog li muaj cov zaubmov ntawm heev. Cov neeg sawv cev muaj peev xwm ntxias teeb nyob rau hauv cov kev ua ub ntawm lub peripheral thiab central tshee systems. Nyob rau hauv kev, muaj kiv taub hau, diplopia, ataxia. Ntawm cov zoo txim ntawm tej yam ntawm cov tshuaj nyob rau hauv cov hlab plawv system kws txawj nco ntsoov khees ua txhaum ntawm intraventricular thiab atrioventricular conduction, txoj kev loj hlob ntawm qhov ntswg tachycardia (nrog ntev-lub sij hawm kev kho mob). Phiv ces muaj xws li arrhythmogenic nyhuv, cov lengthening ntawm QP-ntau, expansion ntawm lub QRS-complex thiab lwm yam kev hloov nyob rau hauv lub ECG qauv. Nyob rau lub hauv paus ntawm kev siv yeeb tshuaj kho "VFS" (phau ntawv qhia ceeb toom txog nws) tshwm liab liab ntawm daim tawv nqaij, mob nyob rau hauv lub taub hau los yog ib tug kev xav ntawm heaviness. Ib txhia neeg yuav tau txais ib cov tshuaj tsis haum cov tshuaj tiv thaiv (sawv pob los yog daim tawv nqaij voos). Nws muaj cov lus qhia txog cov kev phiv los ntawm cov tshuaj "VFS" phau ntawv qhia. Xyuas cov tub txawg txog portability txhais tau tias, nyob rau hauv Feem ntau, zoo. Txawm li cas los, muab lub seriousness ntawm ib co ntawm cov tsis zoo txim ntawm cov tshuaj yog nqa tawm nyob rau hauv lub kaw neeg saib xyuas ntawm ib tug kws kho mob.
Nyob rau hauv cov kev tshwm sim ntawm teeb meem thiab deterioration yuav tsum tam sim ntawd mus ntsib ib tug tshwj xeeb. Nyob rau hauv cov ntaub ntawv no, tus kws kho mob tej zaum yuav xaiv es tsis txhob txhais tau tias "VFS" zoo xws li cov tshuaj.

Thaum tsis muab tshuaj?

Contraindications xws li cardiogenic poob siab, atrioventricular thaiv nyob rau hauv lub thib peb thiab thib ob theem (nyob rau hauv qhov qhaj ntawv los ntawm tus neeg tsav tsheb lub dag lub plawv atherosclerosis). Nws yog tsis tau tso cai rau haus dej haus tshuaj rau tawg nyob rau hauv lub nyuaj lub sij hawm (systolic siab tsawg tshaj li 90 hli / Hg.), Hypertrophy nyob rau hauv lub myocardium ntawm sab laug ventricle cov lus hais. Banned tshuaj nyob rau hauv lub post-infarction cardiosclerosis. Cov tshuaj no yog tsis pom zoo rau lub blockade ntawm txoj cai ceg nras ceg thaiv (thaum ua ke nrog mob nyob rau hauv lub ceg nyob rau sab laug), mob hauv lub plawv tsis ua hauj lwm muaj nuj nqi loj tsawv thiab sab heev. Txhob noj tshuaj mus txog 18 xyoo (vim lub fact tias nws yuav tsis tsim kev ruaj ntseg thiab miv nyuas siv zug ntawm cov kab mob), fructose intolerance. Nws yog tsis tau tso cai rau siv cov tshuaj rau cov neeg uas muaj lub syndrome ntawm impaired resorption galactose / piam thaj, cev xeeb tub, isomaltase tshaj / sucrose. Tsis pom zoo tshuaj rau meem kev txhawj xeeb mus rau lub Cheebtsam. Yog hais tias koj xav siv ib tug laus txoj kev kho rau tus neeg mob, koj xav kom tsis txhob lactation.

Thaum koj xav tau ib koob tshuaj hloov?

Tej zaum kuj muaj yog ib tug yuav tsum tau hloov cov cuab yeej "VFS" tau txais Circuit Court. Cov lus qhia, cov lus los ntawm cov kws txawj muaj cov ntaub ntawv uas txo tus nqi ntawm cov tshuaj los yog ua rau kom lub luv ntawm koob tshuaj yuav pom zoo nrog atrioventricular thaiv nyob rau hauv thawj degree, nyob rau hauv intraventricular conduction mob, bradycardia. Ceev faj ua raws li lub-kaw glaucoma, lub plawv mob (peripheral) hnyav xwm hypertrophy nyob rau hauv prostate ntaub so ntswg. Kho circuits yuav tsum tau nyob rau hauv lub hauv paus ntawm ntsha metabolism hloov conductivity nyob rau hauv Purkinje fibers, blockade ntawm ib qho ntawm ob txhais ceg nyob rau hauv lub nras ceg block. Ceev faj yog yuav tsum tau thaum tau txais lwm yam tshuaj antiritmicheskih ib txhij nrog cov tshuaj "VFS". Xyuas ntawm cov kws txawj yog heev adamant rau qhov teeb meem ntawm kev hloov nyob rau hauv ntau npaum uas tsis muaj cov nyhuv.

Yog xav paub ntxiv,

Ua ntej yuav pib txoj kev kho eliminates mob ntawm dej thiab ntsha tshuav nyiaj li cas nyob rau hauv tus txheej txheem ntawm tau txais cov tshuaj no yog tsim nyog los xyuas kom meej ib qhov thiab ceev faj tswj nws. mob stimulation pib tej zaum yuav ua rau kom nyob rau hauv cov neeg mob uas tau muaj ib lub plawv nres (mob), lub plawv tsis ua hauj lwm, los yog muaj ib co pacemaker. Nyob rau hauv cov kev tshwm sim ntawm kiv taub hau, muab ob npaug rau tsis pom kev, mob taub hau pom zoo kom txo tau cov tshuaj. Thaum lub qhov ntswg tachycardia rau lub hauv paus ntawm ib tug ntev txais tos tshuaj beta-blockers raug raws li xav tau. Cov kev npaj uas tau pom zoo nyob rau hauv uas tsis muaj koob tshuaj. Nyob rau lub hauv paus ntawm kev kho mob yuav tsum tau ceev faj thaum ua ub no uas tej kev ua ub no uas yuav tau nce xim thiab ceev ceev concentration los yog cov tshuaj tiv thaiv.

overdose

Vim lub fact tias cov tshuaj muaj ib tug uas tsis muaj qhov dav ntawm kho kev ua, mob qaug cawv yuav tshwm sim tau yooj yim txaus. Tshwj xeeb tshaj yog yuav muaj lom thaum lawv tau txais ntawm lwm antiarrhythmic tshuaj. Nyob rau hauv overdose cim elongation PR- thiab QT-Team sib, amplitudes kom T-yoj expansion QRS-complex. Tiv thaiv lub keeb kwm ntawm intoxication tshwm sim asystole, bradycardia, tsis contractility nyob rau hauv lub myocardium. Tus neeg mob kuj yog cai sinotrialnaya blockade, txo lub siab cov lus hais, digestive system kev ntshawv siab. Qaug cawv yog nrog los ntawm paroxysmal polymorphic ventricular tachycardia, qhov muag plooj tsis pom kev, kiv taub hau, mob nyob rau hauv lub taub hau. Nyob rau hauv cov kev tshwm sim ntawm ib tug overdose symptomatic kev kho mob yog muaj. Kev kho mob ntawm ventricular tachycardia yog nqa tawm nrog rau kev siv antiarrhythmic tshuaj qeb Kuv A thiab kuv C Expansion QRS-complex, hypotension thiab bradycardia tshem tawm sodium hydrogen carbonate.

Sis nrog rau lwm cov medicaments

Thaum noj ua ke nrog inducers ntawm hepatic microsomal enzymes tshuaj miv nyuas siv zug "VFS" decreases. Qhov no yuav tsub kev pheej hmoo ntawm tshuaj lom los. Thaum tau txais antiarrhythmic tshuaj ntawm lwm cov chav kawm muaj zog yuav ua rau muaj kev loj hlob arrhythmogenic cawv. Lub cuab tam kuj pab tau kev ua si uas tsis yog-depolarizing nqaij hnaiv.

Uas muaj yog ib qho zoo tshuaj nrog ib tug zoo xws li cov mechanism ntawm qhov kev txiav txim?

Txhais tau hais tias "Allaritmin" muaj tib yam kom nquag plias yam khoom uas raws li ib tug tshuaj "VFS" - lappaconitine hydrobromide. Lub medicament hais txog rau cov hoob kawm kuv antiarrhythmic tshuaj. "Allaritmin" Cov tshuaj no muaj nyob rau cov ntsiav tshuaj daim ntawv thiab raws li ib tug tshuaj cov kev txhaj tshuaj rau hauv ib tug nqaij los yog ib tug hauv cov hlab ntsha. Thaum noj ntawm ncauj, cov medicament nyhuv tshwm sim nyob rau hauv hais txog ib teev. Tom qab 4-5 teev, nce mus txog ib tug tshaj plaws efficiency. Duration ntawm nyhuv - 8 teev los yog ntau tshaj. Cov kev taw qhia ntawm tsis nyhuv ntawm cov tshuaj no tshwm sim sai heev - tsis pub dhau 15-20 feeb. Tsis zoo li medicament "VFS" txhais tau tias "Allaritmin" pom zoo haus 3 lub sij hawm txhua txhua hnub 25 mg. Siv cov tshuaj yuav tsum tau ua ntej noj mov. Ntsiav tshuaj ntshaw crush. Nyob rau hauv cov ntaub ntawv ntawm tsis muaj miv nyuas siv zug yuav tau nce ntau npaum thiab zaus ntawm kev txais tos. Tso dej thawj coj los yog nqa tawm maj mam, tshaj 5 feeb. Ntau npaum li koj muab raws li tus luj ntawm tus neeg mob. Pom zoo los ntawm 0.3-0.4 mg / kg. Nyob rau hauv tej rooj plaub (tshwj xeeb yog mob hnyav) tshuaj muab dua tshaj 6 teev. Nyob rau hauv cov nqaij muab 0.4 mg / kg ntawm ua mib ntawm 6 teev. Nws yog muab sau tias tso dej thawj coj los yog tsis pom zoo kom nqa tawm nyob rau hauv tsev. Tshuaj "Allaritmin" muaj cov tib txwv rau kev siv raws li ib tug tshuaj "VFS". Kev kho mob yog nqa tawm nyob rau hauv ib tug lub tsev kho mob nyob rau hauv qhov kev saib xyuas ntawm ib tug kws kho mob thiab ECG xyuas. Qhov no yog tshwj xeeb tshaj yog ib qho tseem ceeb nyob rau hauv cov kev kho mob ntawm cov neeg mob nrog thawj degree atrioventricular thaiv, lub plawv tsis ua hauj lwm, decompensated mob kawg hom.

xaus

Txhais tau hais tias "VFS", rau kev siv ntawm cov uas yuav tsum tau nruj me ntsis tshuaj, zoo li lwm yam antiarrhythmics, belongs rau cov qeb ntawm hwj chim tshuaj. Nyob rau hauv lub qhaj ntawv ntawm kho nyhuv yuav tsum tsis txhob ua rau kom nws tus kheej thaum peb noj lub tshuaj ntau npaum ntawm ib tug tshwj xeeb. Qhov no yog vim lub fact tias muaj yog ib tug uas yuav ntawm intoxication thiab tom ntej teeb meem. Ua ntej koj yuav muab ib tug yeeb tshuaj, tus kws kho mob yuav tsum muab tso rau tus neeg mob paub txog qhov tau tshwm sim thiab contraindications. Nyob rau hauv lem, tus neeg mob yuav qhia txog cov xub ntiag ntawm intolerance, xws li nyob rau hauv keeb kwm, nyob rau hauv tej xov xwm, raws li zoo raws li cov tshuaj uas nws yuav siv sij hawm ntxiv. Ua ntej yuav noj cov tshuaj no yuav tsum tau tshawb annotation.