Tshuaj tua kab mob fluoroquinolones - active fighters rau koj noj qab haus huv

Nyob rau hauv 1962, thaum thawj muaj zog tshuaj ntawm no hauv chav kawm ntawv, tsis muaj ib tug kwv yees nws xws li ib tug zoo. Lawv tau invented raws li ib tug txhais tau tias kho mob txeeb zig, tab sis tom qab ntawd lawv ua nrov tshaj plaws tshuaj tua kab mob. Nyob rau hauv soj ntsuam xyaum, qhov no ntau npaum pab pawg neeg los ua koom thov xwb nyob rau hauv 80-ies ntawm XX caug xyoo. Niaj hnub no, tshuaj tua kab mob, fluoroquinolones yog tsuas irreplaceable nyob rau hauv cov kev kho mob ntawm cov kab mob ua pa. Nyob rau hauv ib ncig ntawm Russia yog nrov thoob ntiaj teb kev faib ntawm cov tshuaj tua kab mob rau yav tom ntej tiam. Tab sis, hmoov tsis, qhov no faib tsis pub cov neeg ua hauj kom qhia txog lawv cov tshuaj muaj pes tsawg leeg thiab spectrum ntawm kev ua si. Yog li ntawd, feem ntau hais txog fluoroquinolones (tshuaj tua kab mob), hais tias, allocating 2 pawg - qub thiab tshiab.

kev faib tshuaj

Rau cov tshuaj qub pab pawg neeg yog "Ofloxacin" tshuaj "enoxacin" "Ciprofloxacin" thiab lwm tus neeg. Tshiab tshuaj tua kab mob - ib tug yeeb tshuaj "sparfloxacin", "Klinafloksatsin", "Moxifloxacin". Txawm li cas los, ib co ntawm cov tsim tshuaj yog tsis muaj, raws li cov kws tshawb fawb kev phiv loj heev thaum uas lawv siv tau pom.

Kev siv cov tshuaj tua kab mob

Qhov no pab pawg neeg ntawm cov tshuaj txwm siv nyob rau hauv cov kab mob ntawm lub mob txeeb zig, plab hnyuv kab mob thiab cov kab mob, kev sib deev kis. Rau cov kev kho mob ntawm cov kab mob ua pa fluoroquinolone tshuaj tua kab mob siv, hmoov tsis, heev ob peb, txawm hais tias lawv yuav tau mus koom ua hauj lwm nyob rau tej hom ntawm pathogens.

Cov tshuaj

Tshuaj tua kab mob Fluoroquinolones zoo absorbed los ntawm tus mob huam, thiab maximize kua concentrate nyob rau hauv cov nqaij tom qab 3 teev tom qab lawv daim ntawv thov. Yog hais tias nyob rau tib lub sij hawm los noj mov, lub haum ntawm lub active ntsis qeeb, tab sis qhov kev txiav txim yuav tsum tau raws li kom nquag plias. Lub mechanism ntawm qhov kev txiav txim ntawm cov tshuaj yog cov inhibition ntawm DNA gyrase thiab topoisomerase IV microbes, thiaj li muaj yog tsis muaj tus ntoo khaub lig-kuj mus rau lwm cov antimicrobial agents. Cov no yog cov siv lug tshuaj tua kab mob rau Gynecology (poj niam deev system kab mob), nyob rau hauv particular inflammations ntawm lub pelvic kabmob, uas tshwm sim vim cov si nyhav ua si ntawm micro-kab uas txeem mus rau hauv lub qaum qhov chaw mos ib ntsuj av. Noj quinolones pom zoo rau ib qho kev npliag plab, tab sis yog permissible thiab siv tom qab noj mov.

phiv

Tshuaj tua kab mob, fluoroquinolones zoo zam lub txim rau raws li qhov haus thiab tso dej tshuaj. Phiv tshua muaj tsawg tsawg, tab sis yog hais tias lawv ua li cas, lawv feem ntau cuam tshuam rau cov kev ua ntawm cov hnyuv thiab lub paj hlwb muaj nuj nqi. Tej zaum koj yuav muaj kev xeev siab, raws plab, mob taub hau, kiv taub hau, tu-sauv, nervousness. Nyob rau hauv Feem ntau, qhov no pab pawg neeg ntawm tshuaj tua kab mob yog yus muaj los ntawm superior pharmacokinetic tsis.

Basic cov kauj ruam fluoroquinolones kauj ruam

1. Lub allergic los ntawm daim nyias nyias mus rau hauv lub cell.
2. Inhibition ntawm cov enzyme DNA gyrase.
3. DNA biosynthesis.
4. Kev puas tsuaj algorithm cell division.
5. Cov kev hloov nyob rau hauv cell qauv.
6. cell tuag.

Qhov no pab pawg neeg ntawm tshuaj tua kab mob yog lug siv nyob rau hauv cov tshuaj, thiab yog hais tias siv yog muaj peev xwm muab kev zoo them nyiaj yug rau tib neeg noj qab haus huv.