"Tenorik": xyuas ntawm cov kws kho mob. Ntsiav tshuaj uas muaj zog siab

Yog tias xws li ib tug yeeb tshuaj, raws li "Tenorik"? Rov qab saib cov yeeb tshuaj muaj peev xwm tawm txhua. Los ntawm kev sib thiab cov kws kho mob thiab cov neeg mob tau yooj yim xaus yuav ua li cas lub hais tias medicament, seb nws ua sab tshua thiab seb daws nrog neeg ua hauj lwm.

Nyob rau hauv no tsab xov xwm peb piav qhia txog nyob rau hauv kom meej lub zog thiab nta "Tenorik" tshuaj. Saib xyuas tus neeg mob noj nws tus kws kho mob txiav txim, kuj yuav me ntsis qis.

Muaj pes tsawg leeg, zoo, hauj lwm, ntim

Kev npaj "Tenorik" (100, 50 mg) yog marketed li dawb yeej ntsiav tshuaj nrog ib tug biconvex zoo thiab ib tug so kab.

Tus qauv ntawm cov tshuaj no muaj ob active cov khoom xyaw: chlorthalidone thiab atenolol. Tsis tas li ntawd, qhov no formulation muaj ntxiv Cheebtsam uas yog nyob rau hauv daim ntawv ntawm cov pob kws starch, sodium lauryl sulfate, lactose, polyvinylpyrrolidone, talc, silica, magnesium stearate thiab isopropanol.

Peb tsis tau hais tias cov ntsiav tshuaj "Tenorik" (ib tug saib xyuas txog qhov cuab tam, koj yuav saib tau nyob rau ntawm qhov kawg ntawm tsab xov xwm) yog them nrog ib tug tshwj xeeb zaj duab xis txheej. Nws muaj methylene chloride, isopropanol, talc, hypromellose, titanium dioxide, macrogol thiab Vaseline roj.

Tau pom tias cov tshuaj yuav ua tau nyob rau hauv sawv hlwv packs los yog ib daim hlab ntawm 28 los yog 100 cov ntsiav tshuaj.

Pharmaceuticals Kws khoom

Yuav ua li cas yog cov tshuaj "Tenorik"? Cov lus qhia rau kev siv (tshuaj nqi yog tsis heev) qhia tias no thaum lawv tseem antihypertensive neeg sawv cev, uas yog tau ua rau ntev-lub sij hawm hypotensive nyhuv.

Cov miv nyuas siv zug ntawm cov tshuaj nyob rau hauv kev saib xyuas vim qhov kev txiav txim ntawm 2 lub Cheebtsam, los yog ib tug es diuretic (chlorthalidone) thiab beta1-adrenergic blocker (atenolol).

Ntsiab zog

Hu atenolol cardioselective beta1-blocker. Cov xim muaj peev xwm ntawm cov tshuaj txo nrog kom muab ntawm cov tshuaj. Atenol twb tsis muaj nrog daim nyias nyias stabilizing thiab sympathomimetic los. Cia li zoo li lwm yam beta-blockers, nws muaj ib tug tsis zoo inotropic teebmeem thiab ho slows lub plawv dhia.

Raws li rau chlorthalidone, nws yog ib tug diuretic (sulfonamide netiazidny). Nws tej kev xaiv ntawm hais xws li tshuaj thiab sodium. Tsis tas li ntawd no tivthaiv tsub kom lub tso pa tawm ntawm bicarbonate, magnesium thiab poov tshuaj. Lub hauv paus ntsiab lus ntawm nws cov antihypertensive txiav txim yog txuam nrog sodium feem.

Atenolol nrog diuretics yog zoo tshaj dua li siv ntawm txhua tus ntawm cov Cheebtsam cais.

Action suav hais tias yog tshuaj no yog khaws cia thoob plaws hauv lub hnub (tom qab ib tug tib koob tshuaj nyob rau hauv ib tug txhua txhua hnub ntau npaum).

Lub kinetics ntawm cov tshuaj

Vim hais tias cov tshuaj "Tenorik" analogs, tus nqi ntawm uas muaj qhia hauv qab no, yog ib tug ua ke txhais tau tias muab lub qhov kinetic zog ntawm txhua tus ntawm cov active tshuaj nyias.

Atenolol yog absorbed los ntawm 40-50% los ntawm cov hnyuv ib ntsuj av. Nws siab tshaj plaws concentration yog mus txog tom qab 4 teev tom qab haus ntawm cov ntsiav tshuaj. Kev sib txuas lus nrog cov nqaijrog yog kwv yees li 8-16%.

Atenolol yog tsis raug mus ci qhia metabolism hauv lub siab. Hais txog 90% ntawm cov absorbed tshuaj tas unchanged rau 8-9 teev. Qhov no lub sij hawm tej zaum yuav tau nce nyob rau hauv kev mob loj raum tsis ua hauj lwm, txij li thaum tshem tawm ntawm atenolol ua los ntawm ob lub raum.

Raws li rau chlorthalidone, nws yog 60% absorbed los ntawm cov hnyuv ib ntsuj av. Cov ntshav concentration mus txog rau nws lub siab tshaj plaws tom qab 12 teev. Kev sib txuas lus nrog cov nqaijrog ntawm kwv yees li 75%.

Chlorthalidone tso tawm los ntawm ob lub raum nyob rau 50 teev.

indications

Los ntawm qhov suav hais tias cov tshuaj muaj zog siab yuav pab zoo heev. Ua tau, arterial tawg, thiab yog ib tug loj, thiab tej zaum qhov tsuas hais rau siv.

Contraindications

Tam sim no, koj paub, yog vim li cas muaj peev xwm yuav muab "Tenorik" ntsiav tshuaj (indications rau yam tshuaj no tau hais saum toj no). Tab sis, hmoov tsis, muaj yog suav hais tias yog siv yeeb tshuaj thiab ib tug impressive daim ntawv teev cov contraindications. Nws tsis pom zoo kom siv sij hawm nrog:

• cardiogenic poob siab;
• pheochromocytoma;
• bradycardia (expressed qaug dab peg);
• mob loj heev mob nyob rau hauv peripheral kev;
• hypotension (progressing mus rau mob hnyav);
• metabolic acidosis;
• AV-blockade 1 thiab 3 degree;
• SSS;
• mob hawb pob hnyav;
• lub plawv tsis ua hauj lwm (nrho ob qho mob thiab mob);
• mob ntshav qab zib;
• vasospastic angina (Prinzmetal lub angina);
• gout;
• obstructive ntsws;
• mob kab mob siab;
• hypoglycemia;
• raum tsis ua hauj lwm nyob rau hauv mob daim ntawv;
• nyob rau hauv lub hnub nyoog ntawm 18 xyoo;
• myasthenia Heavy kev;
• npau taws me ntsis rau cov khoom xyaw ntawm cov tshuaj.

Yuav ua li cas tau "Tenorik" los ntawm ntshav siab?

Tus neeg laus cov neeg mob noj cov tshuaj nyob rau hauv lub medium pom zoo ntau npaum ntawm 100 mg. Cov thawj zaug koob tshuaj ntawm cov tshuaj yuav tsum tau 50 mg ib zaug ib hnub twg.

Raws li rau cov neeg laus, cov tshuaj "Tenorik" lawv muab rau ib tug txawm me me ntau.

Cov neeg mob uas raum tsis ua lag luam yog ntshaw kom txo lub zaus ntawm kev noj cov tshuaj.

Nws yuav tsum tau muab sau tseg tias tom qab heev siv ntawm cov tshuaj nyob rau hauv kev ntsuam xyuas, nws tshem tawm yog yuav tsum tau mus nqa tawm maj.

phiv

Txais tos "Tenorik" Ntsiav tshuaj tej zaum yuav ntxias cov nram qab no sab tshua:

• bradycardia, nce lub plawv tsis ua hauj lwm, txias extremities, orthostatic hypotension, arrhythmia, AV-thaiv, cov tsos mob ntawm sib quas ntus claudication, Raynaud lub syndrome ;
• tsis meej pem, nkees, mob taub hau, hallucinations, mob psychosis, paresthesia, mus ob peb vas viav vias, kiv taub hau, qaug zog, insomnia, tsis meej pem, qhov muag plooj tsis pom kev;
• qhov ncauj qhuav, nce siab transaminases, gastrointestinal mob, hepatotoxicity nrog intrahepatic cholestasis, pancreatitis, xeev siab, cem quav, anorexia;
• leukopenia, purpura, thrombocytopenia, eosinophilia, agranulocytosis;
• alopecia, psoriasiform tshua, qhuav qhov muag, exacerbation ntawm psoriasis, photosensitivity, daim tawv nqaij ua pob ua xyua;
• bronchospasm, hyperuricemia, hypokalemia, hyponatremia;
• impaired zib kam rau ua, ib qho kev nce rau hauv lub xov tooj ntawm antinuclear tshuaj, txo potency.

Cov kev mob tshwm sim tsis zoo los yog tsawg tsawg thiab me me.

nqe analogues

Nqi ntsiav tshuaj "Tenorik" yog 110-120 rubles. Lawv yuav hloov tau cov tshuaj xws li "Atenol", "Dinorik" los yog "Tenoret".

Xyuas ntawm cov tshuaj "Tenorik"

Saib xyuas cov hauj lwm zoo ntawm no lub cuab tam yuav tawm txhua. Raws li rau cov neeg mob thiab cov kws kho mob, lub ntsiab zoo ntawm qhov cuab tam yog:

• cov hauj lwm zoo;
• uas tsis muaj nqi.

Qhov tsis zoo ntawm cov tshuaj no muaj xws li:

• qhov yuav ua rau cov plaub hau tsis thiab txoj kev loj hlob ntawm impotence (long-term care);
• qhov tshwm sim ntawm tshwm sim ntawm qaug dab peg.