Tag nrho cov pneum enzme

Nyob rau hauv tsab xov xwm no peb yuav tham txog ib qho tsis txaus ntseeg enzyme, nyob hauv plab ntawm txhua tus tsiaj, nrog rau tus txiv neej. Cov ntaub ntawv hais txog cov pepsin enzyme, cov ntaub ntawv ntawm nws cov isomers thiab lub luag hauj lwm ntawm cov khoom hauv kev zom cov txheej txheem yuav raug suav hais tias yog.

General views

Ua ntej, cia saib seb hoob kawm ntawm cov enzymes pepsin belongs rau. Qhov no yuav ua rau kom nkag siab tob dua lub ntsiab lus.

Cov kua pepsin hauv thooj av yog hais txog lub tshuab proteolyysis hydrolases thiab yog tsim los ntawm lub plab hnyuv muas, thiab nws cov haujlwm tseem ceeb yog cov kua nqaij ntawm cov khoom noj uas muaj khoom noj nrog peptides. Pepsin - lub enzyme uas cleaves cov nqaijrog nyob rau hauv ib tug acidic ib puag ncig. Nws yog tsim los ntawm cov kab mob ntawm txhua tus tsiaj, thiab cov tsiaj reptiles, cov neeg sawv cev ntawm cov chav kawm ntawv ntawm cov noog thiab ntau ntses.

Tam sim no enzyme belongs rau globular hom proteins, muaj molecular luj ntawm kwv yees li ntawm 34,500. Lub molecule nws tus kheej yog sawv cev raws li ib tug polypeptide saw thiab muaj peb puas plaub caug cov amino acids. Nyob rau hauv nws muaj pes tsawg leeg kuj muaj HPO3 thiab peb cov kev sib tw tsis sib haum xeeb.

Pepsin yog dav siv hauv cov tshuaj thiab cheese ua. Nyob rau hauv lub chaw soj ntsuam nws siv rau lub hom phiaj ntawm kev tshawb fawb ntau ntawm kev kawm cov protein, xws li, tus qauv protein ntau. Pepsin muaj ib qho ntuj tsim - cov kua pepstatin.

Ntau ntawm enzyme

Pepsin muaj kaum ob lub isoforms. Sib txawv ntawm tag nrho cov isomers ntawm pepsin yog nyob rau hauv lub tshuab electrophoretic lub peev xwm, inactivation tej yam kev mob, cov kev ua si proteolytic. Tus cipher ntawm pepsin yog CF 3. 4. 23. 1.

Tus neeg nyob rau hauv lub plab kua txiv muaj xya hom pepsin, thiab tsib ntawm lawv ntog diverge nyob rau hauv ib co qualities:

1. Pepsin nws tus kheej (A) muaj qhov siab tshaj plaws hauv qhov nruab nrab pH = 1.9, thiab thaum nws raug tsa mus rau 6 nws tsis muaj kev vam meej.
2. Pepsin 2 (B) yog maximized hauv nruab nrab pH = 2.1.
3. Hom 3 qhia tau hais tias qhov siab tshaj plaws ntawm kev ua ntawm pH = 2.4-2.8.
4. Ntaus 5, tseem hu ua gastricin, muaj kev ua ntau tshaj plaws ntawm pH = 2.8-3.4.
5. Ntaus 7 nrog pH qhov tseem ceeb ntawm 3.3-3.9 muaj qhov ua tau ntau tshaj plaws.

Tus nqi ntawm lub enzyme hauv plab zom mov

Pepsin yog secreted los ntawm gastric qog nyob rau hauv daim ntawv deactivated (pepsinogen), thiab hydrochloric acid activates lub enzyme nws tus kheej. Nyob rau hauv nws lub hwj, nws kis mus rau hauv ib daim ntawv workable. Ib qho tseem ceeb rau kev ua ntawm qhov enzyme pepsin yog qhov muaj ib qhov chaw nruab nrab ntawm acidic, uas yog vim li cas, thaum lub sijhawm ntawm pepsin mus rau hauv lub duodenum, nws loses nws cov kev ua si, vim nyob rau hauv lub intestine qhov nruab nrab yog alkaline. Cov powzen enzme yog ib lub cim tseem ceeb hauv kev zom ntawm tag nrho chav kawm ntawm hom tsiaj, thiab hauv tib neeg. Cov tshuaj no ua rau cov khoom noj khoom haus ua rau me me peptide thiab cov amino acids.

Nyob rau hauv cov txiv neej thiab cov poj niam, cov zus ntawm no enzyme nws txawv. Cov txiv neej muaj li nees nkaum peb caug gram ntawm pepsin ib xuab moos, thaum ib tug poj niam muaj li nees nkaum peb caug feem pua tsawg. Lub ntsiab lub hlwb, qhov chaw ntawm pepsin qhuav, faib nws nyob rau hauv daim ntawv no ntawm pepsinogen. Tom qab muab cov khoom papids los ntawm N-xaus rau thaum xaus, pepsinogen ua kom muaj zog. Hydrochloric acid ua raws li ib tug catalyst nyob rau hauv qhov tshuaj tiv thaiv ntawm tshuaj hloov. Pepsin muaj protease thiab peptidase zog thiab yog lub luag hauj lwm rau lub disaggregation ntawm proteins.

Therapeutics

Hauv cov tshuaj, pepsin yog dav siv los ua ib yam tshuaj rau qee hom kab mob uas tsis tuaj yeem tsim cov tshuaj no nyob hauv tus neeg mob lub plab. Extract rennet enzyme pepsin los ntawm porcine plab txheej week. Cov tshuaj muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, kis tawm ntawm blisters, nrog ib tug admixture ntawm acidol los yog nyob rau hauv daim ntawv ntawm cov hmoov. Pepsin yog ib feem ntawm qee cov tshuaj sib xyaw ua ke. Muaj ATS-code A09AA03. Ib qho piv txwv ntawm ib qho kev ntsuam xyuas uas muaj cov tshuaj pepsin uas muaj cov tshuaj no yog Menetrie tus kab mob.

Nqaij nyuj pepsin yog ...

Rennet pepsin rennet yog ib qho ntawm cov paub thiab feem ntau yog siv cov ntaub ntawv ntawm no tshuaj. Tus enzyme nws tus kheej yog tsim nyob rau hauv plaub plab hlaub plab. Qhov kev npaj siv rau hauv cov khoom tsim yog tsim los ntawm ob lub enzymes: pepsin thiab chymosin nyob rau hauv natural proportional nqi. Siv cov menyuam yaus cov kua dej tshiab hauv cov cheese, thiab nws cov haujlwm tseem ceeb - qhov tsim los ntawm cov nplais ntawm cov mis nyuj thiab kev koom tes hauv cov txheej txheem ntawm maturation cheese thiab curd khoom.

Nqaij pepsin yog rho tawm los ntawm lub plab ntawm cov nyuj thiab nyob rau hauv lub chaw ua khoom ntawm kev muag khoom, muaj ob theem ntawm ntxuav lub enzyme los ntawm roj thiab impurities uas yog insoluble. Tus txheej txheem ntawm kev ua nqaij nyug pepsin mus txog ob peb theem: extraction txheej txheem, salting tawm thiab sublimation ziab.

Lwm cov ntawv

Tus enzyme pepsin yog ntxiv rau lub oob khab. Nws kuj yog siv ua cheese. Lub rennet pepsin enzyme paired nrog chymosin tas cov enzyme siv quav quav mis.

Tus txheej txheem ntawm folding mis yog hu ua nws cov protein coagulation, uas yog casein, nrog rau tsim ntawm ib tug gel ntawm ib qho chaw yug. Casein muaj ib txoj hlua, thiab tsuas yog ib qho peptide bond yog lub luag hauj lwm rau hom kev haum xeeb ntawm cov protein ntau xwb. Ua tiav pepsin nrog chymosin zoo thiab lub luag hauj lwm rau lub rupture ntawm heev link thiab ua rau lub folding ntawm mis nyuj haus.

Xaus

Ua kom tiav, nws tuaj yeem hais tau tias cov khoom siv roj ntsha no yog ib qho tseem ceeb tshaj plaws hauv cov khoom noj khoom haus hauv plab zom zaub mov hauv plab hauv cov neeg sawv cev ntawm ntau hom kev ua neej nyob. Hauv kev tsim tshuaj thiab tshuaj, cov khoom no yog siv los ua ib yam tshuaj thiab muab ntxiv rau lub rennet enzyme rau cov khoom siv mis nyuj.