"Propranolol": analogues, cov lus qhia rau kev siv, kev piav qhia thiab kev txheeb xyuas

"Propranolol" - ib tug tshuaj teej tug mus rau cov pab pawg neeg ntawm cov xim blockers. Cov tshuaj muaj antianginal los, antiarrhythmic thiab hypotensive. Lub medicament muab rau lub hom phiaj ntawm kev kho mob ntawm ischemic plawv tus kab mob, thyrotoxicosis, tawg. Tshuaj yog zoo nyob rau hauv Neuro dystonia, migraine. Nws yog siv nyob rau hauv qhov kev siv ntawm kev kho mob ntawm lub plawv tsis ua hauj lwm, angina pectoris. Cov tshuaj pab tau lub cev nyob rau hauv myocardial infarction. Lawv kho arrhythmia thiab cardiomyopathy hypertrophic. Thaum tus neeg mob yog tsis haum "Propranolol" counterparts yog xam tau tias yog ib tug kws prescribers uas rau tus neeg mob yog pom.

tso tawm daim ntawv

Koj muaj peev xwm yuav ob hom tshuaj - tshuaj "Propranolol" thiab tshuaj "Propranolol Nycomed". Qhov no yog tib yam tshuaj uas yog ua los ntawm txawv manufacturers nyob rau hauv lub ntsiav tshuaj.

Lub Cheebtsam ntawm cov tshuaj

Cov kev npaj no yog ua rau lub hauv paus ntawm lub active tshuaj propranolol. KOOB ntsiab tivthaiv tej zaum yuav txawv - 10, 40, 80 thiab 160 mg nyob rau hauv nyob tus yeees ntawm txhua ntsiav tshuaj.

Koom haum pab khoom xyaw uas siv nyob rau hauv qhov siv thiab ua cov ntsiav tshuaj yog cov sib txawv thiab nyob ntawm seb lub manufacturers. Yuav kom paub raws nraim li cas yog nyob rau hauv cov tshuaj ua ntej yuav siv nws yog tsim nyog los nyeem hauv phau ntawv.

Tus kho nyhuv ntawm cov tshuaj

Qhia txog lub peev xwm los thaiv lub beta-adrenergic receptors txhais tau tias "Propranolol" phau ntawv qhia. Analogues muaj nyob rau hauv lub cev zoo ib yam li qhov kev txiav txim. Ntsiav tshuaj cuam tshuam rau vascular beta receptors phab ntsa 1 thiab 2. Lub inhibitory ntxim rau cov receptors ua rau yus lub so ntawm vascular phab ntsa, li no xa ntau ntawm cov teeb meem - ntshav siab, muaj zog mob kev thov rau muab cov pa, cov neeg pluag mov ntawm cov as-ham thiab oxygen mus rau cov nqaij thiab kabmob.

Antiarrhythmic kev txiav txim ntawm cov tshuaj txhawb lub tsos ntawm zoo hloov nyob rau hauv lub cev, xws li cov qhov ntswg ntawm automaticity normalization, txo conduction atrioventricular ntawm, tshem tawm ntawm ntau zog excitability ntawm hlwb uas comprise cov myocardium. Ua tsaug rau cov "Propranolol" rov qab los li qub lag luam los ntawm lub plawv, muaj yog tsis muaj cov tshuaj tiv thaiv mus rau sab nraud stimuli, uas tej zaum yuav adversely muaj feem xyuam rau nws lub suab.

"Propranolol" analogues txhawb txoj kev loj hlob ntawm anti-anginal nyhuv uas exhibits paub lub xeev ntawm mob nqaij, txo tus nqi ntawm cov pa yuav tsum tau rau nws lub lag luam. Qhov no txhais tau tias lub plawv yuav tsum tau tsawg pa yuav tsum tau txo, thiab lub zaus ntawm cov lus yog txo heev.

Hypotensive txiav txim no yog raws li nyob rau hauv qhov kev nce nyob rau hauv lub lumen ntawm cov hlab ntsha thiab cov so ntawm lawv phab ntsa. Daim ntawv thov ntawm ib tug tib koob tshuaj ntsiav tshuaj ua rau ib tug txo ntawm cov ntshav siab, lub resulting cov nyhuv yog muab khaws cia tseg rau tsawg kawg 20 teev thaum hmo ntuj. Ruaj hypotensive nyhuv muaj cai tom qab ob lub lim piam ntawm kev siv tshuaj. Cov tshuaj yog tsis haum rau cov nyem ntawm tej yam kev mob nrog ib tug ntse nce nyob rau hauv siab, nws yog qhia rau long-term txoj kev kho rau tawg.

Long-term siv tshuaj ua rau txoj kev loj hlob ntawm cardioprotective los. Qhia ib tug txo nyob rau hauv qhov tshwm sim ntawm kev rov muaj dua ntawm myocardial infarction tom qab xws li kev kho txhais tau tias "Propranolol" xyuas, cov lus qhia. Significantly txo txoj kev pheej hmoo ntawm cia li tuag tshwm sim. Nws yog lub npe hu hais tias cov tshuaj muaj ib tug zoo siv thaum kom intraocular siab.

tshuaj

Tom qab tau txais hauv lub cev lub ntsiab ib feem yog absorbed tshuaj (txog 90%), thaum lub Performance index ntawm bioavailability yog negligible. Kev sib txuas lus nrog cov nqaijrog coj mus rau 93%. Tshuaj los ntawm lub cev yog muab tshem tawm los ntawm cov zis, uas poob metabolites. Qhov hom muaj tsawg tshaj li ib feem pua ntawm cov tshuaj.

zaj lus tim khawv

"Propranolol" analogues qhia tso cai rau koj mus muab cov kev kho mob ntawm tej yam tej yam kev mob thiab cov kab mob. Lawv kho portal tawg thiab arterial, myocardial dystrophy, hyperthyroidism. Tshuaj pab tau yooj yim lub mob nyob rau roj lumen ntawm lub aorta, qhov tseem ceeb co, ntshai tsam, yuav siv tau raws li ib lub cuab tam rau siv nyob rau hauv lub prophylaxis ntawm migraine. Ntsiav tshuaj haum rau txoj kev kho nyob rau hauv lub tub rog lub siab, heart attack myocardial infarction, arrythmia. Lub tshuaj no yog siv rau cov neeg mob uas muaj mitral valve prolapse. Los ntawm indications xws li supraventricular tachycardia thiab qhov ntswg. Muab txhais tau tias ua nyob rau ntawm tus ntsoos ntsoos syndrome, angina pectoris, akathisia, nej sawv vim txoj kev siv cov neuroleptics. Tshuaj rau cov neeg mob nrog pheochromocytoma rau thaum lawv tseem kho. Lub tshuaj no yog siv nyob rau hauv tus tsis muaj zog ntawm zog ua si tom qab lawm los mus tshem tawm nws tsis zoo ces.

Contraindications

Muaj ib co contraindications rau "Propranolol" tshuaj. Analogs yuav tau xaiv nyob rau hauv tus neeg mob qhov twg cov tshuaj yog tsis haum. Contraindications muaj xws li:

• intolerance txhais tau tias yam;
• cardiogenic poob siab;
• bradycardia, thaum lub sij hawm uas lub xov tooj ntawm heartbeats ib feeb yog 55 sp.;
• metabolic acidosis;
• mob hauv lub plawv tsis ua hauj lwm los yog mob ntaub ntawv;
• vasomotor txhaws ntswg;
• sinoatrial thaiv, atrioventricular (2nd, 3rd degree);
• Prinzmetal angina ;
• tsis tshua muaj ntshav siab;
• Siv cov insulin;
• syndrome nrog qhov ntswg;
• muaj lub sij hawm thaum lub sij hawm uas tus tam sim no heev yoo mov heev;
• teeb meem nrog peripheral kev (decompensation kauj ruam);
• yav tas los kis kev taw qhia tus kab mob nyob rau hauv uas cuam tshuam tej hlab cua txhob, mob hawb pob, bronchospasm muaj.

Tseem muaj tej yam kev mob nyob qhov twg ceev faj yog yuav tsum tau. Nyob rau hauv cov nram no ntau, koj muaj peev xwm xaiv es tsis txhob ntawm cov tshuaj "Propranolol" analogues, txhais:

• myasthenia Heavy kev;
• ntshav qab zib (decompensated, subcompensation);
• mob nqaij insufficiency (asthma), kab mob siab, mob raum;
• spastic mob plab;
• kev nyuaj siab;
• atrioventricular thaiv (thawj degree);
• psoriasis;
• nce muaj nuj nqi ntawm cov thyroid caj pas;
• mob ntaub ntawv ntawm cov hlab ntsws;
• tsis tshua muaj ntshav qab zib;
• mob hawb pob;
• hnub nyoog laus;
• Thaum lub sij hawm cev xeeb tub, breastfeeds.

tshuaj kho mob

Cov neeg mob uas kub siab yuav tsum tau coj ib hnub ob zaug tshuaj koob tshuaj ntawm 40 mg rau ib zaug xwb koob tshuaj. Nws nce yog tau tsis pub dhau 14-28 hnub. Yog hais tias tsim nyog, ntsiav tshuaj yuav tau haus txhua hnub nyob rau hauv ib tug ntau npaum ntawm 80 rau 160 mg. Tus zaus ntawm lub tau txais txhais tau tias yog tib yam.

Thaum tachyarrhythmia neeg laus cov neeg mob haus peb los yog plaub lub sij hawm txhua txhua hnub los ntawm 10 mus rau 30 mg rau ib txais tos "propranolol" txhais tau tias. Analogs yuav siv tau, yog tias cov khoom no tsis haum. Yau cov neeg mob nrog rau ib yam teeb meem ntawm yeeb tshuaj muab nyob rau hauv ib tug npaum li ntawm los ntawm 0.2 mus 0.4 mg ib kilogram lub cev hnyav. Tus zaus ntawm daim ntawv thov txhais tau tias - li peb los yog plaub zaug ib hnub twg.

Raws li ib tug tiv thaiv kev ntsuas nyob rau hauv cov neeg mob uas muaj ntawv qhia angina taw plaub noj cov tshuaj no txhua txhua hnub. Ib tug tib koob tshuaj ntawm 20 mg. Nws nce yog ua tau rau xya hnub. 40 mg ntawm yeeb tshuaj yog coj nyob rau tib tus nqi, 80 mg - me ntsis tsawg feem ntau (ob zaug).

Tom qab myocardial infarction prophylaxis yuav tsum tau. Khiav nws yuav medicament "Propranolol". Loj haum ib koob tshuaj yog 40 mg, cov tshuaj receptions ib hnub twg yuav tsum tau muab peb. Ua kom cov tshuaj kom txog thaum ib tug tshaj plaws ntawm 80 mg.

Migraine tiv thaiv kev ntsuas yuav tsum tau ntsib nrog rau cov kev siv ntawm 40 mg ntawm cov tshuaj ib hnub ob zaug. Yuav tsum tau ib qho kev nce nyob rau hauv koob tshuaj rau 80 mg, noj tshuaj txhua txhua hnub zaum yuav muaj ob los yog peb, thiab cov me nyuam - peb los yog plaub. Muab xam los ntawm cov tshuaj rau cov neeg mob nrog me me ua nyob rau hauv kev saib xyuas ntawm lawv cov luj, ib kilogram ntawm - los ntawm 1.5 mus rau 2 mg.

Thyrotoxicosis - ib tug kab mob nyob rau hauv uas cov tshuaj yog muab 10 mg tab sis tsis ntau tshaj li 40 rau tau txais peb los yog plaub zaug ib hnub twg.

Yog hais tias koj npaj yuav pheochromocytoma txoj kev kho, cov tshuaj yog ua ke nrog tus alpha blockers.

phiv

Yuav tsum xyuam xim rau dab tsi txiav txim qhov tshwm sim los ntawm cov tshuaj "Propranolol" phau ntawv qhia. Analogs xyuas - tsis yog tsis tseem ceeb cov lus qhia, yuav txhawb cov kev xaiv ntawm cov tshuaj rau kev kho mob. Yuav kom txoj kev pheej hmoo ntawm kev phiv tshuaj ntawm lub cev yog tsawg heev, nws yog tsim nyog los ua tib zoo nyeem cov lus qhia, nws yog ib pab tau mus ntsib nrog.

Tshuaj yog siv tsis yuav ua mob cov hlab plawv system tshwm sim los ntawm teeb nyob rau hauv lub central lub paj hlwb, lub endocrine system. Tau tsis zoo ces nyob rau ib feem ntawm cov hnyuv, tej zaum yuav disturb tus txheej week thiab daim tawv nqaij. Ntawm cov kev phiv uas muaj npe nyob rau hauv cov lus qhia - ua pa muaj teeb meem. Tej zaum yuav muaj lwm yam tshwm sim.

analogs nqi

Ua ntej yuav khoom "Propranolol" tshuaj analogues, tus nqi yog feem ntau kawm cov neeg mob. Yuav tshuaj yuav ua tau rau 16-75 rubles. Nqe yog txiav txim los ntawm tus xov tooj ntawm cov ntsiav tshuaj ib pob. Hloov cov tshuaj yuav ua tau "Propranobene" medicaments "obzidan" los yog "Inderal". Koj yuav tau ua kev kho mob "Inderalom LA", "Inderalom".

Los ntawm kev siv rau cov tshuaj "Propranolol" cov lus qhia rau kev siv, nqe, analogs muab ntaub ntawv tseem ceeb uas yuav pab ua qhov zoo tshaj plaws kev txiav txim siab thaum xaiv cov tshuaj thiab kev kho mob.

Xyuas

Xyuas feem ntau zoo. Lawv qhia tias cov tshuaj kho mob yog feem ntau zoo. Nyob rau hauv tas li ntawd, muaj ntau yam yog txaus siab nrog cov uas tsis muaj nqi tshuaj. "Propranolol" tswj kom cov ntshav siab nyob rau hauv ib tug ib txwm muaj, sai sai tau tshem ntawm lub plawv palpitations. Tshuaj thiaj li tsos mob ntawm kab mob plawv, eliminates tib neeg siab ntsws xav. Tsis zoo xyuas mas feem ntau yog cov neeg tawm vim hais tias ntawm kev phiv loj heev uas tej zaum yuav tshwm sim thaum lub sij hawm txoj kev kho. Tej zaum kuj muaj heev tsis muaj zog, pw tsaug zog teeb meem, npau suav phem.