Poov tshuaj iodide. qhia

Poov tshuaj iodide - ib tug npaj muaj ib qho inorganic iodine. Nyob rau kev txais neeg kawm mus rau lub epithelial hlwb ntawm lub follicle yuav siv sij hawm qhov chaw nyob rau hauv cov thyroid caj pas oxidation txheej txheem. Raws li ib tug tshwm sim, nyob rau hauv qhov kev txiav txim ntawm ib tug peroxidase enzyme iodide tsim elemental iodine molecule comprises tyrosine. Yog li radicals tyrosine (iodinated) yog condensed nyob rau hauv lub thyronine. Yog li tsim T3 (tri-iodothyronine) thiab T4 (thyroxine). Tsim complex thyroglobulin thyronine thiab sawv raws li ib tug depot daim ntawv ntawm cov tshuaj nyob rau hauv lub qog follicular colloid thiab muab cia rau hauv daim ntawv no rau ib tug ob peb lub lis piam los yog hnub. Thaum tsis muaj iodine piav cov txheej txheem yog ntxhov, thiab poov tshuaj iodide reimburses tsis muaj peev xwm. Nyob rau hauv no formulation pab los synthesis ntawm cov tshuaj hormones (thyroid).

Nyob rau hauv cov ntaub ntawv ntawm ib tug ib txwm iodine nyob rau hauv lub cheeb tsam qhov tshaj ntawm iodides tawm biosynthesis. Thyroid hormones tsis ncaim ntawm thyroglobulin, lowers tus rhiab heev ntawm lub qog caj pas mus rau lub thyrotropic lawm pituitary uas nkoos nws xauv (hormone) secretion.

Poov tshuaj iodide (eyedrops, ntsiav tshuaj, qhov ncauj tov) sai sai absorbed. Muaj ib tug ntau muab faib rau cov tshuaj nyob rau hauv cov kua tawm thiab tag nrho cov cev nqaij.

Poov tshuaj iodide qhia kom tau txais cov kev kho mob thiab kev tiv thaiv ntawm teb goiter, kev tiv thaiv ntawm goiter tsis tshua mob heev tiv thaiv lub keeb kwm ntawm lub complex txoj kev kho ntawm lub qog hormone tshuaj.

Ntau npaum tus kws kho mob xaiv ib lub zuj zus. Nyob rau hauv cov nqe lus ntawm iodine hnub nyiaj txhais tau rau cov me nyuam - los ntawm 50 mus rau 100 micrograms. Cov tshuaj rau cov neeg laus - los ntawm 100 mus 200 micrograms.

Tau txais txhais tau tias tej zaum yuav ua rau o ntawm lub qhov ntswg mucosa, angioedema, urticaria, poob siab, eosinophilia. Phiv ces cov tshuaj "poov tshuaj iodide" cov lus qhia yog txob taus, tachycardia, raws plab (nyob rau hauv cov neeg mob tom qab plaub caug xyoo), pw tsis taus, muaj zog tawm hws. Nyob rau hauv tej rooj plaub, cov kev siv ntawm siab koob tshuaj (ntau tshaj 300-100 mg) npaj hyperthyroidism (tshwj xeeb tshaj yog nyob rau hauv cov neeg mob nyob rau hauv cov neeg laus nrog diffuse los yog nodular goiter lom).

Contraindications mus rau yeeb tshuaj "poov tshuaj iodide" qhia hu hypothyroidism qhia thiab dej ntws yaug txaus, tshuaj lom adenoma, npau taws me ntsis rau iodine, diffuse los yog nodular goiter (toxic). Tsis muab cov tshuaj nyob rau hauv dermatitis herpetiformis Duhring.

Poov tshuaj iodide thaum lub sij hawm cev xeeb tub thiab lactation yog tso cai rau kev siv tsuas yog nyob rau kho koob tshuaj pom zoo los ntawm tus kws kho mob. Lub active tivthaiv yuav kis tau los ntawm cov placental barrier. Qhov no yuav ua rau tsim ntawm goiter thiab hypothyroidism nyob rau hauv lub fetus.

Cov tshuaj yuav tsum nyob rau hauv tas niam cov kua mis. Nyob rau hauv daim ntawv thov ntawm koob tshuaj nyob rau hauv excess of 1 mg, muaj yog ib tug uas yuav ntawm hypothyroidism nyob rau hauv tus me nyuam mos.

Nyob rau hauv cov neeg mob uas raum insufficiency nyob rau tom qab ntawm cov kev kho mob yuav muaj hyperkalemia.

Hyperkalemia zaum yuav tshwm sim nrog concomitant vysokodozirovannoy iodine kho nrog poov tshuaj-sparing diuretics, hypothyroidism thiab goiter - nrog lithium txoj kev kho. Thiocyanate thiab perchlorate yuav inhibit iodine uptake los ntawm cov thyroid caj pas.

Siv cov tshuaj yuav ua kom ua xua. Txawm li cas los, ib co neeg mob qhia rau lub ntsej muag pob txuv. Thaum cancelling txhais tau tias ib tug uas yuav siv sij hawm qhov chaw, tab sis tus mob heev npaum li cas. Nyob rau hauv cov kev tshwm sim ntawm tej lub xeev thaum uas siv cov tshuaj "poov tshuaj iodide" Neeg pom zoo mus tham ib tug tshwj xeeb. Tej zaum yuav tsum tau kho ntau npaum los yog hloov los ntawm lwm cov txhais tau tias.

iodine tshuaj no feem ntau muab thaum lub sij hawm cev xeeb tub raws li ib tug txij nkawm txoj kev kho. Txawm li cas los, cov kev siv nyob rau hauv hnub lub sij hawm yuav tsum tau soj ntsuam los ntawm ib tug tshwj xeeb.