"Paroxetine": cov lus qhia rau kev siv, xyuas. tshuaj analogues

Dab tsi yog meant tshuaj "Paroxetine"? Cov lus qhia rau kev siv ntawm cov tshuaj yuav tsum nyob rau hauv no tsab xov xwm. Tsis tas li ntawd tawm ntawm nws koj paub txog tej contra-indications thiab yog muaj nyob rau ntawm cov tshuaj no, yog hais tias nws muaj tej yam tshwm sim tsis zoo, nyob rau hauv dab tsi daim ntawv no yog muaj thiab yuav ua li cas cov tshuaj ua num ua ke nrog lwm yam tshuaj.

Muaj pes tsawg leeg, ntim thiab daim ntawv ntawm cov tshuaj tso tawm

Tshuaj "Paroxetine" mus rau cov muag khoom nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, zaj duab xis-coated. Lawv yog cov yeej thiab lenticular zoo, dawb xim, thiab txoj kev pheej hmoo ntawm ib tug ntxhib saum npoo av.

Lub active tshuaj yog xam los ntawm peb txhais tau tias paroxetine hydrochloride hemihydrate. Tsis tas li ntawd, cov tshuaj nyob rau hauv nws muaj pes tsawg leeg muaj kev pab txhawb nqa cov ntsiab nyob rau hauv daim ntawv ntawm colloidal silicon dioxide, microcrystalline cellulose, crospovidone, calcium hydrogen phosphate, copovidone, talc thiab magnesium stearate.

Ntsiav tshuaj "Paroxetine" yog muag nyob rau hauv sawv hlwv packs ntawm 10 daim uas yog muab tso rau hauv ib lub cardboard lub thawv.

Lub pharmacological kev txiav txim ntawm cov tshuaj

Yuav ua li cas yog cov tshuaj "Paroxetine", uas analogues yuav muaj npe ib tug me ntsis ntxiv? Nws yog ib qho kev nyuaj siab. Nws yog ib qho inhibitor ntawm (xim) serotonin reuptake hlwb neurons. Qhov no yog dab tsi txiav txim nws anti-depressive los thiab ua tau nyob rau hauv cov kev kho mob ntawm ntshai teeb meem no thiab obsessive-compulsive ntshawv siab.

Saib hu rau medicament muaj ib tug heev tsawg affinity rau α2-, α1- thiab β-adrenoreceptors raws li m-holinoretseptorami, dopamine, 5HT1-li, 5HT2 zoo li thiab histamine H1-receptors.

Koj psychomotor zog ua txhaum cov tshuaj "Paroxetine"? Xyuas ntawm cov kws kho mob hais tias cov tshuaj muaj tsis ntxim rau cov tib neeg psyche tsis zoo. Ntxiv mus, nws tsis potentiate lub depressant los ntawm ethanol rau psychomotor zog.

Liam soj ntsuam tau pom ib tug antidepressant xws tsis muaj zog activating zog xwb yog hais tias nws yog xeem nyob rau noj tshuaj npaum cas siab tshaj cov yuav tsum tau rau inhibition ntawm serotonin reuptake. Peb tsis tau hais tias cov tshuaj no tsis ua rau ib tug tseem ceeb kev hloov nyob rau hauv cov ntshav siab ntau ntau, EEG thiab lub plawv dhia.

Cov tshuaj ntawm ib tug kws kho ntaus ntawv

tshuaj "Paroxetine" raws li absorbed? Cov lus qhia rau kev siv, tiag tiag kws kho mob hais tias tom qab qhov ncauj thawj coj ntawm lub active tshuaj yog absorbed los ntawm cov hnyuv thiab yog metabolized los ntawm lub siab.

Lub chaw concentration ntawm medicament nyob rau hauv cov ntshav tiav los ntawm 1-1.7 lub lis piam tom qab pib ntawm yeeb tshuaj kho mob. Lub active ingredient ntawm cov tshuaj yog feem faib nyob rau hauv ntaub so ntswg. Nyob rau hauv cov ntaub ntawv no, nws tsuas yog ib feem pua yog pom nyob rau hauv cov ntshav. Kev sib txuas lus nrog cov proteins ntawm qhov kev txiav txim ntawm 95%.

Antidepressant metabolized nyob rau hauv lub siab. Raws li ib tug tshwm sim, tsaug zog metabolites raug tsim. Lawv sai sai tshem tawm los ntawm lub cev, thiab muaj ib tug tsis tshua muaj pharmacological kev ua si thiab muaj tsis ntxim rau cov tshuaj los ntawm cov tshuaj.

tshuaj "Paroxetine" raws li tso tawm? Nco ntsoov, kws muab tshuaj kev qhia uas hais txog 64% ntawm lub active tshuaj yog tawm ua ke nrog cov zis, thaum lub seem 36% - nyob rau hauv cov hnyuv (nyob rau hauv cov kua tsib).

Cov tshuaj ntawm cov tshuaj nyob rau hauv tshwj xeeb soj ntsuam lub sijhawm

Lub concentration ntawm active tshuaj nyob rau hauv cov ntshav ntshav nce nyob rau hauv kev ua txhaum ntawm lub raum thiab lub siab, raws li zoo raws li cov neeg laus.

Indications rau kev siv ntawm ib tug kws kho ntaus ntawv

Nyob rau hauv tej rooj plaub, cov neeg mob cov kws kho kev nyuaj siab "Paroxetine"? nyob rau hauv daim ntawv thov ntawm lub cuab tam daim ntawv qhia muaj cov nram qab no daim ntawv teev cov nyeem tej no:

• txhua yam ntawm kev nyuaj siab, xws li mob loj heev endogenous, reactive, thiab yog nrog los ntawm kev ntxhov siab vim;
• panic mob, xws li agoraphobia;
• obsessive-compulsive tsis meej (OCD los yog abbreviated);
• generalized kev ntxhov siab vim teeb meem;
• muaj kev ntxhov siab tsis meej, yog li ntawd-hu ua kev phobia.

Contraindications rau kev siv ntawm ib tug kws kho ntaus ntawv

Nyob rau hauv tej rooj plaub, nyob rau hauv tsis muaj cov ntaub ntawv yuav siv tsis tau nyob rau hauv cov neeg mob kev nyuaj siab "Paroxetine"? nyob rau hauv daim ntawv thov ntawm lub cuab tam daim ntawv qhia muaj xws li cov nram qab no daim ntawv teev cov contraindications:

• tsis ruaj tsis khov qaug dab peg;
• txhawb kev siv ntawm monoamine oxidase inhibitors, raws li zoo raws li ib tug ob-lub lim piam tom qab lawv tshem;
• cov me nyuam muaj hnub nyoog;
• hnub lub sij hawm;
• Npau taws me ntsis mus rau yeeb tshuaj Cheebtsam;
• thaum lub sij hawm pub niam mis.

Siv nrog huab ceev faj

Nyob rau hauv dab tsi mob yuav tsum tau tshuaj kom tsawg ntawm antidepressant "Paroxetine"? Cov lus qhia rau kev siv hais tias qhov no npaj muab nrog ceev faj rau cov neeg mob nrog siab tsis ua hauj lwm, lub kaum ntse ntse-kaw glaucoma, raum tsis ua hauj lwm, mania, benign prostatic hyperplasia, convulsive lub xeev, mob mob, qaug dab peg. Nyob rau hauv tas li ntawd, cov txhawb kev siv ntawm invalid tshuaj thiab cardioversion, raws li zoo raws li cov tshuaj uas ua rau kom cov uas muaj feem yuav los ntshav. Peb yuav tsum tau them rau kev mloog kom lub xub ntiag ntawm muaj tej yam los ntshav mob thiab yog conducive mus xws li tus kab mob kas.

Antidepressant "Paroxetine": yuav ua li cas noj cov tshuaj?

Peb xav tshuaj noj ntawm ncauj ib zaug ib hnub twg (nyob rau hauv lub yav sawv ntxov) thaum lub sij hawm noj tshais. Ntsiav tshuaj yuav tsum tau nqos tag nrho, ntxuav cia nrog dej dawb.

Thaum lub sij hawm ua ntej peb lub lis piam tom qab pib ntawm kev kho mob ntau npaum yog tom ib lub zuj zus. Nws yog tom qab tom (yog tias tsim nyog).

Thaum lub sij hawm ntev kev nyuaj siab pom zoo npaum li cas ntawm cov medicament yog 20 mg ib zaug ib hnub twg. Yog hais tias yuav tsum tau, lub koob tshuaj yog maj nce los ntawm 10 mg. Max tau txais cov tshuaj yuav tsum tsis txhob ntau tshaj 50 mg.

Rau obsessive compulsive tsis meej thawj zaug koob tshuaj ntawm ib tug antidepressant yog 20 mg ib hnub twg. Tom qab ntawd, nws tsub kom mus rau 10 mg. Cov pom zoo nruab nrab txhua hnub koob tshuaj rau xws li ib tug sib txawv yog 40 mg. Nyob rau hauv mob yuav tsum nws muaj peev xwm muab tau ntau zog mus rau 60 mg.

Yog hais tias tus neeg mob muaj ib tug ntshai teeb meem, koj yuav chiv tau mus txog rau 10 mg ntawm cov tshuaj ib hnub twg. Yuav kom txo tau cov tau pheej hmoo ntawm kev ntshai cov tsos mob nyob rau hauv ib tug tom ntej koob ntawm cov tshuaj no yog ntau zog los 10 mg. Nyob rau nruab nrab, thaum xws li ib tug sib txawv yog tau siv 40 mg "paroxetine" nyob rau hauv cov sij hawm, lub siab tshaj plaws pes tsawg tus - 50 mg.

Thaum kev phobia los yog muaj kev ntxhov siab mob medicament pib ntim yuav tsum tsis txhob ntau tshaj 20 mg ib hnub twg. Yog hais tias tom qab xws li ib tug kev kho mob lub Desired nyhuv tsis tau tiav, ces 2 lub lis piam lub koob yog maj zog rau lub siab tshaj plaws, uas yog mus txog li 50 mg ib hnub twg.

Nyob rau hauv generalized kev ntxhov siab vim teeb meem kho thiab thawj zaug ntim ntawm lub medicament yog 20 mg ib hnub twg

Yog hais tias tus neeg mob tus mob siab los yog raum tsis ua hauj lwm, cov pom zoo koob tshuaj yuav tsum tau 20 mg ib hnub twg.

Cov neeg laus ib hnub twg yuav tau noj tsis muaj ntau tshaj li 40 mg ntawm cov tshuaj.

Nyob rau hauv thiaj li yuav tiv thaiv kom txhob ntsoos ntsoos cov tsos mob tsis txhob noj cov tshuaj no yog pom zoo maj.

tus neeg mob ntawm overdose

Puas muaj tus neeg mob ntawm overdose nrog antidepressants xws li "Paroxetine", "Fluoxetine"? Kws txawj nco ntsoov tias kev siv ntawm ib tug loj tus naj npawb ntawm cov tshuaj lawv yeej adversely cuam tshuam tib neeg lub cev. Tus neeg mob kev xeev siab, qhov ncauj qhuav, qhov ntswg tachycardia, ntuav, convulsions, co, bradycardia, mydriasis, ntxhov siab, txob taus, tawm hws, nystagmus, nce ntshav siab, somnolence, thiab nodal atherosclerosis.

Nyob rau hauv tsis tshua muaj heev zaus thaum siv cov tshuaj nrog rau lwm cov psychotropic tshuaj, thiab cawv tej zaum yuav raw tus neeg mob thiab cov variation ntawm lub se rau ECG. Rau hauv loj heev overdose, tus neeg mob yog serotonin syndrome thiab rhabdomyolysis.

Yuav ua li cas nyob rau hauv tej lub sijhawm? Nyob rau hauv cov ntaub ntawv ntawm cov tshuaj overdose "Paroxetine" yuav tsum pais plab lavage, thiab coj tus txais carbon. Yog hais tias tsim nyog, symptomatic kev kho mob.

phiv

Yuav ua li cas yog cov kev phiv los ntawm cov tshuaj yuav ua rau "Paroxetine"? Xyuas ntawm cov kws kho mob hais tias qhov no lub cuab tam tiag tiag yuav pab tau tsim kev phiv tshuaj. Cov no muaj xws li nram qab no tej yam kev mob thiab cov kab mob:

• Nyob rau hauv ib feem ntawm lub hauv paus poob siab system thiab peripheral tshee system: mania, nkees nkees, tsis meej pem, co, serotonin syndrome, qaug zog, hallucinations, insomnia, nervousness, kiv taub hau, depersonalization, qaug zog, ntshai tsam, qaug dab peg, ntxhov siab, amnesia, extrapyramidal teeb meem, myoclonus, ntxhov siab vim.
• Licas: nqaij tsis muaj zog, arthralgia, myopathy thiab myalgia.
• Tsis totaub: qhov muag plooj thiab qhov muag plooj tsis pom kev raws li ib tug tag nrho.
• Mob txeeb system: nquag tso zis los yog tso zis tuav tseg.
• Hnyuv: ntau zog los tsis qab los noj mov, kab mob siab, saj hloov, qhov ncauj qhuav, xeev siab, raws plab, ntuav, thiab cem quav.
• Me nyuam system: anorgasmia, kev sib deev kawg, hyperprolactinemia los yog galactorrhea, impotence thiab ejaculation ntshawv siab.
• Plawv system: orthostatic hypotension.
• Kev tsis haum tshuaj: khaus, tawm pob, angioedema, thiab urticaria, ecchymosis.
• Lwm yam variations: rhinitis, tawm hws, tsis tsim nyog secretion ntawm antidiuretic lawm, hyponatremia.

Sis nrog rau lwm cov kev kho mob txhais tau hais tias

Lub simultaneous siv antacids tsis cuam tshuam rau pharmacokinetic tsis thiab qhov haum ntawm cov tshuaj "Paroxetine".

Contraindicated rau cov ib-lub sij hawm siv los ntawm cov nyiaj ua ntej rau peb nrog Mao inhibitors.

Tib mus txais tos medicament "paroxetine" nrog cov tshuaj uas inhibit lub siab enzymes, yuav tsum tau mus ntxov thawj koob tshuaj.

Antidepressant cas sim haum los ntshav nyob rau hauv lub keeb kwm yav dhau ntawm ib-lub sij hawm siv "ntawm cov warfarin."

Tib mus siv ntawm cov medicament "paroxetine" nrog tricyclic antidepressants, aspirin, atypical neuroleptics, narcotics yuav muab thiab txhais tau tias phenothiazine series txhawb cov ntshav txhaws txheej txheem.

Tib mus thawj coj nrog serotonergic agents (xws li "tramadol" thiab "sumatriptan") yuav yooj yim ua rau enhanced serotonergic los.

Nws yog ib qho tseem ceeb rau koj nco ntsoov!

Yuav kom tsis txhob muaj cov kev loj hlob ntawm ib tug neuroleptic syndrome (phem), ib tug yeeb tshuaj nrog huab ceev faj "Paroxetine" tshuaj rau cov neeg mob uas noj antipsychotics.

Cov neeg laus nyob rau tom qab ntawm cov tshuaj tej zaum yuav tsim hyponatremia.

Thaum thawj cov cim qhia ntawm qaug dab peg thiab mania antidepressant txoj kev kho yog nres.

Thaum lub sij hawm ua ntej lub lim piam ntawm kev kho mob nrog "paroxetine" yuav tsum tau ceev faj xyuas ntawm tus neeg mob vim tau tua lawv tus kheej.

Thaum lub sij hawm txoj kev kho yuav tsum tsis txhob haus cawv vim lawv enhanced lom nyhuv.

Me nyuam yaus siv

Tshuaj "Paroxetine" yog tsis muab rau cov me nyuam, raws li nws muaj kev ruaj ntseg thiab ua tau nyob rau hauv cov kev kho mob ntawm cov neeg mob nyob rau hauv pab pawg neeg no tsis tau tsim muaj.

Antidepressant "Paroxetine": counterparts

Cov tshuaj yuav tau muab hloov los ntawm "Paroxetine"? Nws yuav tsum tau muab sau tseg hais tias qhov no tshuaj, muaj ib tug heev ob peb counterparts. Ntawm lawv, nws yuav ntshaw kom highlight qhov nram qab no tshuaj: "Reksetin", "Adepress", "Pliz", "APO-Paroxetine", "Aktaparoksetin", "Paxil", "sertraline", paroxetine hydrochloride hemihydrate, "" Sirestill "thiab thiaj on.

Yuav kom yuav tag nrho ntawm cov tshuaj nyob rau hauv cov khw muag tshuaj, koj ua tau tsuas yog los ntawm cov tshuaj.

Xyuas ntawm medicament

Tshuaj "Paroxetine" muaj ib tug ntau ntawm mixed xyuas, ob qho tib si los ntawm cov tub txawg thiab los ntawm cov neeg mob. Nyob rau hauv ib tes, nws yog praised rau nws muaj txhawb rau sai tshem tawm ntawm txhua yam kev nyuaj siab (xws li mob loj heev endogenous, reactive, thiab yog nrog los ntawm kev ntxhov siab vim), raws li zoo raws li ntshai, obsessive-compulsive, generalized thiab kev ntxhov siab vim teeb meem. Nyob rau hauv lwm yam - ntau cov neeg mob hais tias tam sim ntawd tom qab cov tshuaj lawv tsim ib tug loj heev tooj kev phiv tshuaj. Raws li ib tug tshwm sim, cov neeg tau txawm tau mus nres cov kev kho mob.

Nyob rau hauv kev, kws txawj nco ntsoov tias "Paroxetine" - qhov no yog ib tug zoo heev thiab npaum tshuaj COPES nrog neeg ua hauj lwm rau nws. Txawm li cas los, nws yuav tsum tsuas yog siv rau nws npaj lub hom phiaj tshwj xeeb.