Neuraminidase inhibitors: ib daim ntawv teev cov tshuaj rau siv cov lus qhia

Lub thoob ntiaj teb system ntawm cov tshuaj kev faib faib tag nrho cov keeb kwm ntawm cov khoom nyob rau hauv cov tshuaj pab pawg neeg. Lub hauv paus rau qhov no yog qhov pharmacological kev txiav txim ntawm cov tshuaj. Nthuav tsab xov xwm no yuav qhia tau rau koj txog ib tug xws li pab pawg neeg. Nws muaj neuraminidase inhibitors. Koj yuav nrhiav tau tawm yog dab tsi active cov khoom xyaw yog lawv lub hauv paus, raws li tau zoo raws li tau ntsib nrog lawv pauv npe.

neuraminidase inhibitors

Ua ntej peb yuav tham txog cov tshuaj, nws yog tsim nyog los tuab no pharmacological pab pawg neeg. Neuraminidase - ib yam ntawm cov enzyme. Nws yog tam sim no nyob rau hauv daim nyias nyias nto ntawm tag nrho cov kab mob khaub thuas tus kab mob. Thaum kev sib cuag nrog ib tug cell ntawm tib neeg lub cev yog tso tawm tej yam tshuaj lom. Hais tias lawv ua rau cov tsos ntawm cov tsos mob: kub taub hau, tsis muaj zog, mob taub hau thiab thiaj li nyob.

Neuraminidase inhibitors txeem mus rau hauv tus kab mob no. Lawv suppress cov kev ua ntawm pathogenic microorganisms, tiv thaiv lawv cov sib npaug thiab tom ntej kev sib cuag nrog kev noj qab nyob hlwb. Cov kev loj hlob ntawm tej tshuaj pib nyob rau hauv 1960. Tus thawj ua nws tau mus kawm nyob rau hauv kom meej qhov txhais tau tias ntawm lawv cov nyhuv rau tus kab mob.

Neuraminidase inhibitors: tshuaj thiab lawv active cov khoom xyaw

Niaj hnub nimno pharmacology muaj mus yuav ob lub ntsiab tshuaj uas yuav tsiag ntawv los ntawm tej yam ua. Lawv pauv npe "Tamiflu" thiab "Relenza". Ob khoom uas siv rau kev tiv thaiv thiab kev kho mob ntawm kev mob ua npaws, qhov sib txawv hom. Neuraminidase inhibitors muag tsuas yog nyob rau cov tshuaj. Nws kuj tso cai rau kev siv ntawm cov tshuaj nyob rau hauv lub tsev kho mob thaum tau hais tseg. Tsis txhob noj cov tshuaj no rau cev xeeb tub cov poj niam thiab niam. Contraindications siv yuav cov me nyuam nyob rau hauv lub hnub nyoog ntawm 5 xyoos. Raum thiab hepatic tsis ua hauj lwm yog ib tug ua rau kev sib tham cais ua ntej yuav siv.

Lub active sib txuas ntawm cov tshuaj yog distinguished lub npe thiab hom kev saib xyuas. "Tamiflu" tshuaj muaj nyob rau hauv cov qauv ntawm cov oseltamivir. Lub medicament yog tawm nyob rau hauv daim ntawv ntawm cov tshuaj nrog particulate cov ntsiab lus rau hauv kev siv. Tshuaj "Relenza" - qhov no txhais tau tias nqus tau pa. Active tivthaiv yog zanamivir.

dosing npaj

Nyob rau hauv dab tsi txoj kev yog siv neuraminidase inhibitors (flu)? Koj twb paub hais tias ob ntawm tshuaj los ntawm koj tus kws kho mob. Yuav kom yuav cov tshuaj uas koj xav tau ib tug tshuaj. Yog li ntawd, ntau npaum thiab ntev ntawm koom haum saib xyuas feem ntau xaiv ib tug kws. Tab sis phau ntawv kuj muaj cov lus qhia txog qhov no:

• Cov tshuaj "Tamiflu" nyob rau hauv cov neeg laus thiab cov me nyuam tom qab 12 xyoo yog siv ob zaug ib hnub twg rau ib ntsiav tshuaj. Hoob no ntev yog 5 hnub. Rau cov me nyuam nyob rau hauv 12 xyoo yog dua li siv nyob rau hauv ib tug npaum li ntawm kev ncua 30-75 mg oseltamivir (nyob ntawm seb lub cev hnyav) ob zaug ib hnub twg.
• "Relenza" tshuaj tauj ntawm nqus tau pa. Phau Ntawv Qhia kom siv 10 mg ntawm lub compound (2 nqus tau pa) ib hnub ob zaug. Ntxiv txoj kev kho 5 hnub. Rau kev tiv thaiv ntawm kev siv ntawm 10 mg ntawm cov tshuaj ib hnub ib zaug rau 10 hnub.

Cov miv nyuas siv zug thiab kev phiv tshuaj

Kws txawj hais tias lub neuraminidase inhibitors ntawm kab mob khaub thuas tus kab mob zoo dua lub ntxov kho mob yog pib. Yog li ntawd nws yog tsim nyog nyob rau hauv cov thawj tsos mob sab laj ib tug kws kho mob. Tus kws kho mob yuav muab tshuaj rau qhov tsim nyog kev tshawb fawb uas yuav pab txiav txim seb lub neej yav tom ntej tactics. Ob tshuaj yog zoo tiv thaiv kab mob khaub thuas tus kab mob (xws li mutant). Tsis zoo li lwm yam tshuaj antiviral, neuraminidase inhibitors qhia kev kawm ntawv siab. Twb ib ob peb teev tom qab thawj zaug daim ntawv thov tus neeg mob yuav yooj yim dua.

Nws yog ib qho tseem ceeb hais tias "Relenza" thiab "Tamiflu" yuav muab tag nrho nrog rau lwm cov tshuaj los kho tus mob khaub thuas, nws cov tsos mob thiab cov teeb meem. Los ntawm txoj kev, thiab cov tshuaj kuj muaj kev fab. Piv txwv li, ib tug tshuaj txau, "Relenza" yuav ua rau ua tsis taus pa thiab bronchospasm. Feem ntau yeej tsis haum tshuaj tshwm sim nyob rau hauv daim ntawv ntawm edema. "Tamiflu" txhais tau tias noj. Yog li ntawd, nws muaj ntau yam tsis zoo los: mob plab mog, kev tsis haum tshuaj, exacerbation ntawm lub raum thiab hepatic kab mob, neuropsychiatric ntshawv siab.

Yuav kom saib lub ntsab lug

Neuraminidase inhibitors yog ib tug uas zoo nyob rau hauv sib ntaus tawm tsam kab mob khaub thuas tus kab mob. Thaum lub sij hawm kev mob kev nkeeg, tej zaum lawv yuav tsum noj nrog ib tug saib kom tiv thaiv. Tab sis kws txawj tsis pom zoo kom siv cov tshuaj tsis tas. Nyob rau hauv tas li ntawd, koj yuav tsis tau cov tshuaj nyob rau hauv lawv tus kheej. Yog hais tias koj tus kws tshuaj muaj mus yuav cov tshuaj "Tamiflu" thiab "Relenza" tsis muaj ib tug tshuaj, koj yuav tsum paub hais tias nws yuav forged. Kev siv cov tshuaj tej zaum yuav tsis tsuas txo tus kab mob no, tab sis yuav ua tau txoj sia. Nyob twj ywm noj qab nyob zoo!