Nce lactate: Ua, Kev Kho Mob

Nyob rau hauv lub niaj hnub ntiaj teb no, science tsis sawv tseem. Cov kab mob yog ua tib zoo kawm, thiab zaum no tab tom nrhiav rau txoj kev mus nrog lawv. Cov kws kho mob feem ntau muab rau kev ntsuam xyuas uas tsis to taub los ntawm cov neeg, tab sis hais tias qhov no tshwm sim tej zaum yuav paub meej tias yog refute tus kws kho mob kev ntshai. Thiab tsom xam ntawm LDH, lactate dehydrogenase nce tshwj xeeb tshaj yog qhia. Yuav ua li cas yog nws thiab dab tsi yog qhov yuav tshwm, peb yuav tham ntxiv lawm.

Yuav ua li cas yog LDH

Lactate - nws yog ib tug ntawm cov enzymes, uas qhia tau hais tias lub xub ntiag ntawm puas hlwb. Nws yog ob lub nyob rau hauv cov ntshav thiab nyob rau hauv cov nqaij nyob rau hauv ntau nyiaj. Nyob rau hauv tus txheej txheem ntawm kev ua pa nyob rau hauv lub hlwb ntawm lactic acid ntsev yog tsim. Lactate dehydrogenase pab rau nws txoj kev hloov mus rau hauv pyruvic acid, uas yog muab kev koom tes nyob rau hauv lub high-oxidation txheej txheem. Nws muaj txhawb rau sai tso tawm ntawm lub zog los ntawm qabzib, uas yog tsim nyog rau nqaij contraction, biochemical dab. Subtotal - cov khoom uas yooj yim muab tshem tawm los ntawm lub cev - carbon dioxide thiab dej. Yog hais tias tsis txaus oxygen yog nkag, lub enzyme accumulates tshwm sim pathology uas leeb lub disintegration ntawm lub hlwb. Lawv yuav ua rau lub fact tias lactate dehydrogenase nce. Qhov ntsuas no yog rhiab heev rau txoj kev puas tsuaj ntawm tus xovtooj ntawm lug.

Lactate dehydrogenase, Yog hais tias cov txheej txheem ntawm nyob rau hauv nqis kev txiav txim ntawm kom muaj nuj nqis, yog nyob rau hauv xws nruab nrog cev thiab cov nqaij:

• Nyob rau hauv lub ob lub raum.
• Lub plawv mob.
• Skeletal leeg.
• Txiav.
• Po.
• Tshuaj kuaj ntawm peb lub cev - lub siab.
• Lub ntsws.
• Nyob rau hauv cov ntshav ntshiab.

hom LDH

Lub enzyme lactate dehydrogenase muaj ob peb cov ntaub ntawv uas txawv los ntawm txhua lwm yam isoenzymes, thiab muaj nyob rau hauv txawv ntaub so ntswg. Nyob rau hauv lub concentration ntawm ntau dua isoenzyme nyob rau hauv ib qho kev hloov khoom nruab nrog, muaj cov hom ntawm cov enzyme:

• LDG- 1 - tsuas yog nyob rau lub plawv thiab ntshav.
• 2 - nyob rau hauv leukocytes.
• 3 - nyob rau hauv lub ntsws cov ntaub so ntswg.
• LDH - 4 - lub feem ntau nyob rau hauv lub raum, lub tsev me nyuam, pancreas.
• 5 - yog kuaj nyob rau hauv daim siab thiab striated nqaij.

Vim hais tias ntawm no nws peev xwm yuav xaus ntawm cov nuj nqis uas muaj zog LDH isoenzyme, thiab qhia hais tias tus kab mob no.

Thaum zoo li no tsom xam yog tshuaj

Muaj ntau ntau tej yam kev mob nyob rau hauv uas nws yog tsim nyog los tswj cov theem ntawm LDH:

• Nyob rau hauv cov kab mob ntawm lub hepatobiliary system.
• Tom qab myocardial infarction.
• Nyob rau hauv paub ntau yam hlav.
• Yog hais tias koj xav tau los mus txiav txim lub hom anemia.
• Nyob rau hauv cov kab mob nrog nce hemolysis.
• Nrog ntse mob nyob rau hauv lub siab.
• Yog hais tias muaj yog txhab ntawm lub siab los yog ob lub raum.
• Rau ib daim ntawv ntsuam xyuas ntawm cov ntaub so ntswg thiab cov nqaij tom qab lub yeej ntawm kev raug mob los yog kev mob nkeeg.

Cawv yam rau lub txiaj ntsim ntawm tus tsom xam

Yog hais tias koj tus kws kho mob vim hais tias koj tau tsa lactate dehydrogenase, refute los yog paub meej tias nws ua tau tsuas yog xeem.

Ib tug ntshav kuaj rau LDH swb nyob rau hauv thaum sawv ntxov nyob rau ib npliag plab. Ntshav yog twv los ntawm cov hlab ntsha. Ua ntej mus rau lub kev kho mob chav tsis yuav tsum tau tshwj xeeb cov khoom noj. Cia li yuav paub hais tias muaj yam uas yuav pauv tau. Uas tej zaum yuav cuam tshuam rau cov neeg ntawm tus tsom xam tshwm sim:

1. Noj vitamin C yuav txo tau cov theem ntawm LDH nyob rau hauv cov ntshav.
2. Daim ntawv thov cardioversion hnub ua ntej tus me nyuam ntawm tus tsom xam.
3. Ntawm daim tawv nqaij muaj teeb meem.
4. Cov ntsiab lus ntawm dej cawv nyob rau hauv cov ntshav.
5. Thrombocytosis.
6. Kev siv cov hemodialysis.
7. Muaj ib co tshuaj, xws li "aspirin", "mithramycin" anesthetics, fluoride yuav tsa cov theem ntawm cov enzyme.
8. Ntev li ib ce muaj zog.

Tej yam zoo tej zaum yuav muaj kev cuam tshuam cov kev tshwm sim, tab sis nws tsis txhais hais tias muaj pathological dab nyob rau hauv lub cev.

Ua ntej koj yuav kawm tau cov ntsiab lus ntawm cov enzyme nyob rau hauv lawv cov ntshav, nws yog tsim nyog los tham nrog koj tus kws kho mob yog dab tsi tshuaj yuav tsum tau muab tso tseg ua ntej yuav mus rau lub lab.

Nws yog ib qho tseem ceeb los mus thauj thiab khaws cov ntshav mus de li, raws li uas tsis yog raws kev cai yuav ua nyob rau hauv hemolysis ntawm cov ntshav, thiab raws li ib tug tshwm sim uas muaj zog lactate dehydrogenase.

Indicators LDH nqi rau cov me nyuam thiab cov laus

Indicators lactate cov ntsiab lus hloov nrog lub hnub nyoog. Cov laus ib tug neeg tiav niam txiv, cov tsawg lawv. Yog li, lub concentration ntawm LDH:

• Cov me nyuam mos - mkkat rau 28,9 / L.
• Los ntawm 1 xyoo mus txog 3 xyoos - txog li 14,2 mkkat / l.
• Cov tub hluas ntawm 7 xyoo mus rau 12 lub xyoo - mus 12.7 mkkat / l.
• Hluas nkauj los ntawm 7 xyoo mus rau 12 lub xyoo - mus 9.67 mkkat / l.
• Txiv neej - mkkat rau 11,4 / L.
• Cov poj niam - mkkat rau 7,27 / l.

LDH qhov tseem ceeb yuav ua tau saum toj no los yog hauv qab no lub cai.

Nce lactate - Ua

Nce nqi muaj cai nyob rau hauv cev xeeb tub cov poj niam thiab tom.

Yog hais tias raws li ib tug tshwm sim uas muaj zog lactate tsom xam. Yog vim li cas rau qhov no - txoj kev loj hlob ntawm cov hauv qab no hais tias:

• Heart attack myocardial infarction.
• Viral mob siab.
• Mob npuas paug.
• Oncology.
• Mob pancreatitis.
• Txawv txav raum kab mob.
• Anemia.
• Leukemia.
• Ib txoj kev mob nyob rau hauv uas muaj yog ib tug uas nws kim heev neej puas hlwb: poob siab, mob hypoxia, loj cheeb tsam ntawm kev kub nyhiab.
• Nws kim heev kev raug mob.
• Mob ntawm lub licas.

Txawm li cas los, tsis tau tsuas yog no tsom xam qhia hauv lub xub ntiag ntawm tus kab mob nyob rau hauv lub cev. Nws yog tsim nyog los nqa tawm ntxiv kev soj ntsuam. Cov kev ua ntawm isoenzymes, tus kws khomob tshwjxeeb yuav tsum tau los mus txiav txim lub localization ntawm tus kab mob.

Tus nqi ntsuas LDH isoenzymes

Yog hais tias ib tug los ze zog saib ib qho kev nce ntawm lactate dehydrogenase tej hom, koj yeej paub twb ntawm lub sij hawm mus tsim lub pathology.

Ua los yog LDH-1 LDH-piv 1 / LDH-2 raug rau cov nram no tej yam kev mob:

• Mob myocardial infarction.
• Hemolytic anemia megaloblastic.
• Mob raum necrosis.
• Nyob rau hauv lub xub ntiag ntawm hlav ntawm cov txiv neej thiab poj niam genitalia.

Kom LDH-5 yog yus nrog:

• Daim siab mob.
• Cancer.
• Raug mob ntawm skeletal leeg.

Ua LDH-2 LDH-3 yog feem ntau cai nyob:

• Mob leukemia.
• Mob granulocytosis.

Ua kom LDH-3, tej zaum nyob rau hauv ib feem LDH-4 thiab LDH-5 yog feem ntau rooj plaub, yog tias muaj:

• raum kab mob.
• Koj muaj teebmeem kev embolism.
• Lub plawv tsis ua hauj lwm, uas tsim lub ntsws cov ntaub so ntswg.

Ua LDH-4-LDH 5 yog kuaj tau hais tias koj paub hais tias:

• Tsis ncig vim muaj ib tug tsis muaj zog lub plawv.
• lub siab puas.
• Cov kev raug mob ntawm cov nqaij.

LDH nyob rau hauv cov me nyuam

Yog hais tias peb tham txog cov me nyuam, peb yuav tsum coj mus rau hauv tus account tus me nyuam lub hnub nyoog. Cov me nyuam ntsuas LDH saum toj no. Tsis tas li ntawd, ua ntej koj mus rau tus kws kho mob, nws yog tsim nyog yuav tau taug qab dab tsi tshuaj tus me nyuam yuav siv sij hawm, thiab tuav rawv nws lub cev ua si. Yog hais tias lactate dehydrogenase nce tus me nyuam, yog vim li cas tej zaum yuav tshwm sim los ntawm ib yam ntawm cov pathologies piav saum toj no. Nco ntsoov tias yog hais tias tus me nyuam yog tsis haum, nws kuj muaj kev cuam tshuam lub sij hawm, tshwj xeeb tshaj yog loj me nyuam mos liab eczema los yog mob hawb pob. Cov kev raug mob thiab doog tej zaum yuav pauv tus tsom xam, thiab muaj cov anemia nyob rau hauv cov me nyuam.

Yog hais tias tus thawj tshwm sim ntawm ntau dua li ib txwm, koj yuav tsum xeem mus kuaj soj ntsuam xyuas nws cov neeg. Yog hais tias, txawm li cas los, muaj zog lactate dehydrogenase nyob rau hauv tus me nyuam, nws yog tsim nyog los ua kev cai ib tug tag nrho cov kev xeem. Ib tug, qhov no daim duab tsis muab txoj cai rau qhov kawg mob thiab tshuaj kho mob.

Kev kho mob ntawm cov kab mob thiab cov kev hloov nyob rau hauv LDH

Yog hais tias lactate dehydrogenase ntau zog, cov kev kho mob ntawm tus kab mob muaj peev xwm maj coj no daim duab rau hauv lub cev.

1. Nyob rau hauv mob raum LDH nce exacerbations nyob rau hauv mob chav kawm ntawm tus kab mob no tseem qub. Tsub kom tom qab hemodialysis.
2. Nyob rau hauv daim siab mob npuas paug thiab kab mob siab indicators LDH yog dab tsi, thaum lub sij hawm ntawm tus kab mob exacerbation qhov tseem ceeb nce.
3. Thaum anemia LDH siv rau differential mob.
4. Ib tug plawv nres yog nce LDH, thiab tom qab 10-14 hnub, los rov qab mus rau qub. Control ntawm no enzyme tso cai tus kws kho mob los soj ntsuam qhov kev kawm ntawm kev kho mob.

Yog hais tias thaum pib ntawm tus kab mob nce lactate ces thaum muaj kev vam meej kev kho mob ntawm anemia, leukemia, mob kab mob LDH kev ua si yog txo.

Ntawm no yog ib tug tsis yooj yim heev tsom xam, uas feem ntau ntawm peb yog tsis txawm paub. Thiab nws puv tawm, yuav ua tau ntau yam los qhia rau koj tus kws kho mob.