"Macropen": analogues, cov lus qhia rau kev siv, tiag tiag

Yuav ua li cas yog cov tshuaj "Macropen"? Ib tug analogue ntawm lub cuab tam, nws tso tawm cov ntaub ntawv, daim ntawv thov kev, indications, contraindications thiab sab no los yuav tsum tau muab nthuav hauv qab no. Peb kuj qhia koj tias tham txog cov tshuaj, cov neeg mob thiab seb nws muaj peev xwm txais yuav cov me nyuam.

Muaj pes tsawg leeg, ntim, zoo

Kev npaj "Macropen" (analog txhais tau tias yuav tsum teev hereinafter) yog ua nyob rau hauv ob hom sib txawv. Cia peb xav txog lawv nyob rau hauv ntau yam.

• Granules npaj rau ncua kev kawm ntawv (noj). Cov tshuaj tsis muaj pom impurities, nws muaj ib tug txiv kab ntxwv xim thiab lub teeb aroma ntawm txiv tsawb. Lub active ingredient ntawm no zoo protrudes midecamycin acetate. medicament kuj muaj xws li ancillary khoom xws li methyl parahydroxybenzoate, mannitol, propyl parahydroxybenzoate, sodium saccharin, citric acid, silicone antifoam, anhydrous sodium phosphate hydrogen, hypromellose, txiv tsawb tsw, thiab xim daj. Cov tshuaj yog muaj nyob rau hauv hwj uas tsaus nti iav. Lawv muab tso rau hauv ib pawg ntawm cov duab los qhia thiab muaj ib tug ua tiav dosing diav.
• "Macropen" tshuaj. Phau ntawv hais tias daim ntawv no ntawm cov tshuaj dawb dawb, puag ncig, me ntsis biconvex zoo nrog beveled npoo. Nyob rau hauv ib tes muaj yog notching ntsiav tshuaj. Lub active tivthaiv xws npaj protrudes midecamycin. Raws li cam siv polacrilin poov tshuaj, microcrystalline cellulose, magnesium stearate thiab talc. Qhov no daim ntawv ntawm cov tshuaj "Macropen" analogue ntawm nws ( "Azithromycin" hom) yog muag nyob rau hauv sawv hlwv packs, uas yog muab tso rau hauv ib pawg ntawm cov duab los qhia.

Lub pharmacodynamic thaj chaw ntawm cov tshuaj

Los ntawm ib tug analogue ntawm cov tshuaj "Macropen" nws tus kheej yuav yog ib tug txhais tau tias ntawm tshuaj tua kab mob. Lawv yuav mus rau cov pab pawg neeg ntawm macrolides.

Lub hauv paus ntsiab lus ntawm cov lag luam ntawm xws li ib tug yeeb tshuaj yog hais tias nws cheeb protein synthesis nyob rau hauv lub hlwb ntawm cov kab mob nyob rau hauv me me koob tshuaj exerting ib bacteriostatic nyhuv, thiab loj - bactericidal.

Lub siab kho cov hauj lwm zoo ntawm cov tshuaj cai nrog Gram-zoo kab mob xws li Staphylococcus, Clostridium, Listeria thiab tus kab mob Streptococcus korinobakterii thiab Gram - Bacteroides, Campylobacter, Helicobacter, Haemophilus influenzae, Moraxella.

Nyob rau hauv tas li ntawd, cov tshuaj "Macropen" analogue ntawm nws heev feem ntau muab nyob rau hauv lub xub ntiag ntawm cov intracellular kab mob: ureaplasma, chlamydia, mycoplasma.

tshuaj

tshuaj "Macropen" ntev npaum li cas yog absorbed? Phau ntawv hais tias tom qab noj cov tshuaj hauv nws kiag li thiab sai sai absorbed los ntawm cov hnyuv ib ntsuj av.

Qhov siab tshaj plaws concentration ntawm cov tshuaj nyob rau hauv cov ntshav ntshiab yog cai tom qab 1-2 xuab moos. Nyob rau theem no nws yog khaws cia kom txog rau thaum 6 teev.

Tib mus noj kom tsawg tsis cuam tshuam rau haum ntawm cov tshuaj, thiab tsis txo nws cov concentration hauv cov ntshav. Nyob rau hauv no kev twb kev txuas, nws yog pom zoo kom noj cov tshuaj no khwv ua ntej ib tug noj mov.

Qhov siab tshaj plaws nqi ntawm cov tshuaj nyob rau hauv cov parotid caj pas, lub ntsws thiab cov tawv nqaij. Drug metabolism tshwm sim nyob rau hauv lub siab. Yog tso tawm ua ke nrog rau cov kua tsib thiab los ntawm ob lub raum.

Indications ntsiav tshuaj thiab kev rho tawm

Yog vim li cas muab tshuaj "Macropen"? Analogs thiab tsis tshua kim thiab kuj zoo heev tshuaj tiv thaiv kab mob, uas yog tshwm sim los ntawm kab mob rhiab rau lub active tshuaj:

• kab mob ntawm lub genitourinary system (e.g., Mycoplasma, Ureaplasma, Chlamydia);
• ua pa kab mob (mob ntsws, pharyngitis, tonsillitis, sinusitis, otitis, ntsws);
• kab mob ntawm daim tawv nqaij thiab qog ua kua week;
• hnoos thiab mob qa hawj foob;
• enteritis, uas tau tshwm sim los ntawm Campylobacter.

Nws yuav tsum tau muab sau tseg tias cov tshuaj no tej zaum yuav muab rau cov neeg mob uas tsis tau tso tshuaj tua kab mob tus neeg saib xyuas penicillin.

Contraindications rau kev siv ntawm cov tshuaj

Txawv teb chaws thiab domestic counterparts "macrofoams" raws li zoo raws li lub tshuaj nws tus kheej yog tsis pom zoo rau:

• rhiab heev rau midecamycin;
• mob loj heev hepatic puas;
• hnub nyoog txog peb lub xyoos (rau cov ntsiav tshuaj).

Txoj kev ntawm daim ntawv thov thiab ntau npaum lub ntawm cov ntsiav tshuaj

Yuav ua li cas kuv yuav tsum tau siv cov tshuaj "Macropen" (zoo)? Cov lus qhia rau kev siv yuav tau qhia rau cov neeg mob tias cov tshuaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj muab txhua 8 teev.

Cov me nyuam uas ntau tshaj 30 kg thiab cov laus cov tshuaj yog pom zoo kom noj ntau tshaj 400 mg peb zaug ib hnub twg. Maximum hnub koob tshuaj rau cov neeg laus yog 1600 mg.

Child uas tsawg tshaj li 30 kg yog muab 20-40 mg ib kg. Nyob rau tib lub hnub koob tshuaj noj tshuaj yog muab faib ua 3 lub sij hawm. Rau hauv loj heev mob, cov saum toj no tus nqi ntawm cov tshuaj yuav tau nce mus 50 mg rau ib kg.

Dosing thiab dosing ncua kev kawm ntawv

Yuav ua li cas mus txais ncua kev kawm ntawv, "Macropen"? Analogs (rau cov me nyuam) thiab lub cuab tam rau nws tus kheej yaj dej dawb. Qhov no daim ntawv yog tshuaj nyob ntawm seb tus me nyuam hnyav. Cov tshuaj no yog ob zaug ib hnub twg.

• nrog ib tug luj ntawm 0-5 kg - txog 3,75 mL ntawm lub npaj tov;
• nyhav 5,10 kg - txog 7.5 ml;
• nrog ib tug luj ntawm 10-15 kg - txog 10 ml;
• nrog ib tug luj ntawm 15-20 kg - txog 15 ml;
• nrog ib tug luj ntawm 20-25 kg, hais txog 22.5 ml.

Siv cov tshuaj nyob rau hauv cov me nyuam

Nyob rau hauv Pediatrics deals nrog cov txhais tau tias nws pom tau hais tias qhov zoo tshaj thiab muaj kev nyab xeeb. Cov kws kho mob yuav luag yeej tsis sib tsoo nrog cov mob tshwm sim.

Tshuaj "Macropen» tsis tshua muaj txhawb rau dysbiosis, uas yog heev nyob rau hauv lub sij hawm ntawm lwm yam tshuaj tua kab mob nrog.

Nyob rau hauv cov kev kho mob ntawm "Makropenom" cov me nyuam tsis txhob muab ntxiv anti-fungal cov tshuaj.

Qhov no txhais tau tias rau cov me nyuam yog ua nyob rau hauv ib tug tshwj xeeb daim ntawv (granules). A ncua kev kawm ntawv tsis saj zoo zoo nkauj. Nyob rau hauv no hais txog, thaum lub sij hawm kev kho mob ntawm cov tub ntxhais cov neeg mob lawv yeej tsis muaj tej teeb meem nrog cov tshuaj.

Nws yuav tsum raug sau tseg hais tias muaj yog ib tug heev heev ntawm zoo tswv yim los ntawm cov niam txiv uas hais tias lub kho nyhuv ntawm cov tshuaj no yog yeej ib txwm siab, txawm nyob rau hauv tus neeg mob qhov twg lwm yam tshuaj tua kab mob penicillin powerless.

Cov nyom zoo tom qab haus

Txais ntawm cov nyiaj tsis tshua muaj ua rau kev phiv tshuaj. Txawm li cas los, nyob rau hauv tej rooj plaub, cov tshuaj yuav tseem pab mus rau rov tshwm sim ntawm cov hauv qab no txawv txav:

• Nyob rau hauv ib feem ntawm lub digestive ib ntsuj av tau: stomatitis, tsis qab los noj mov, ntuav, daj ntseg, hnov xeev xeev siab, zoo nkaus li ntawm heaviness nyob rau hauv lub plab, muaj zog siab transaminase kev ua si, ntev thiab mob raws plab (nrog pseudomembranous mob plab).
• Cov kev tsis haum: bronchospasm, daim tawv nqaij ua pob liab vog, khaus tawv nqaij, pob thiab eosinophilia.
• Lwm yam: nkees thiab tsis muaj zog.

tshuaj cov kev sib tshuam

Thaum simultaneous thawj coj nrog cov tshuaj "Carbamazepine" txo nws pom nyob rau hauv daim siab thiab tsub kom tus concentration hauv cov ntshav. Qhov no ua ke nrog ntawm cov tshuaj tsub kom kev pheej hmoo ntawm tshuaj lom los ntawm lub yav tas (ataxia, urinary tuav, tu-sauv).

Thaum co-xeem nrog ib tug yeeb tshuaj "warfarin" tsub kom qhov uas yuav los ntshav, nrog "ergotamine" thiab "ergometrina" - cai peripheral vascular spasm (tau ischemia thiab gangrene ntawm lub extremities), thiab nrog "cyclosporine" - tsub kom kev pheej hmoo ntawm nephrotoxicity.

Tshwj xeeb cov lus qhia hais txog kev txais cov tshuaj

Raws li cov lus qhia, xam tias yog qhov txhais tau tias muaj cov nram qab no nta:

• Raws li nyob rau hauv lub siv ntawm lwm yam antimicrobial agents, ntev-lub sij hawm kev kho mob "Makropenom" tus neeg mob tej zaum yuav tsim tshuaj kuj kab mob.
• Yog hais tias cov tshuaj yuav ua rau lub caij nyoog lub plab, nws qhia tias txoj kev loj hlob ntawm pseudomembranous mob plab.
• Thaum lub sij hawm ntev-lub sij hawm kev kho yog tsim nyog los saib xyuas cov kev ua ntawm daim siab enzymes. Qhov no yog tshwj xeeb yog muaj tseeb ntawm cov neeg mob nrog impaired lag luam ntawm no hloov khoom nruab nrog.
• Xws li ib tug yeeb tshuaj, xws li mannitol (pom nyob rau hauv cov nplej) tej zaum yuav ua kom raws plab.
• Thaum lub xub ntiag ntawm haum acetylsalicylic acid daj zas, yog muaj nyob rau hauv nyob tus yeees ntawm cov kev npaj yuav ntxias tsis haum tshuaj loj (e.g. bronchospasm).

Tshuaj "Macropen": analogues ntawm cov tshuaj thiab lawv cov nqi

Tam sim no analogs ntawm lub active ingredient nyob rau hauv cov tshuaj nyob rau hauv kev saib xyuas tsis muaj nyob. Nrog hais txog lub cuab tam teej tug mus rau tib lub pharmacological pab pawg neeg (macrolides 2nd tiam), cov lawv yog cov nram qab no cov tshuaj: "Azithromycin", "clarithromycin" thiab "Josamycin". Lawv kuj siv nyob rau hauv cov kab mob kab mob. Tab sis ua ntej yuav siv cov tshuaj tua kab mob rau cov kev kho mob ntawm cov me nyuam thiab cov laus, nws yog tsim nyog los tham ib tug kws kho mob los yog cov menyuam yaus, raws li lawv tej zaum yuav muaj sib txawv heev txoj kev ntawm cov thawj coj, ntau npaum thiab kev phiv.

Nqe ntawm cov ntsiav tshuaj thiab ncua kev kawm ntawv "Macropen" (analogues xyuas ntawm kev npaj yuav sib tham txog nyob rau hauv no tsab xov xwm) yog 270-360 rubles. Yog hais tias xws tshuaj tua kab mob nqi yog siab dhau heev lawm, peb xav kom koj hloov nws nrog "azithromycin". Nws nqi no tsuas yog 85-100 rubles.

Nrog kev xav txog cov tshuaj, xws li "clarithromycin" thiab "josamycin", lawv tus nqi yog siab tshaj lub thawj (los ntawm 380 rubles).

Testimonials

Xyuas ntawm cov tshuaj "Macropen" feem ntau zoo. Feem ntau ntawm lawv twb tawm hauv tus neeg mob tom qab thawj coj ntawm cov tshuaj nyob rau hauv lub qhov ntswg.

Nyob rau hauv Feem ntau, lub high efficiency ntawm cov tshuaj yog cai tsuas rau nws raws sij hawm lub sij hawm. Yog hais tias koj noj cov tshuaj raws li qhia nyob rau hauv cov lus qhia (kev kho mob ntev ntawm 1-2 lub lis piam), tus neeg mob 'mob yog kev txhim kho sai sai txaus. Raws li ib tug txoj cai, xws li ib tug kev kho mob rau tus neeg mob yuav tsum tau tsis hno. Nws yog ib qho tseem ceeb mus ua kom tiav tag nrho cov chav kawm ntawm kev kho mob. Txwv tsis pub, tus kab mob no yuav ua mob.

Nws yuav tsum raug sau tseg hais tias muaj ntau ntau hauv kev txheeb xyuas nyob rau hauv lub nkag ncua kev kawm ntawv (cov me nyuam me). Nyob rau hauv Feem ntau, cov niam txiv tau txaus siab rau qhov kev tshwm sim ntawm kev kho mob. Raws li lawv, cov tshuaj sai sai txaus pab thaum koj hnoos, xws li nyob rau hauv protracted.

Nyob rau hauv tsawg tus neeg mob, los mus tiv thaiv tus me nyuam raws plab thiab muab probiotics xws li "Baktisubtil" thiab "Linex".

Thaum lub sij hawm txais tos, qhov qhia ntawm cov tshuaj, ib co niam txiv hais cov tsos ntawm cov me nyuam nram qab no phiv: nkees nkees, xeev siab thiab ntuav. Nyob rau hauv xws li mob, noj tshuaj yog muab tso tseg thiab hloov los ntawm ib tug ntau ruaj ntseg sib npaug.