"Kordinik": cov lus qhia rau kev siv, analogs thiab xyuas

Antianginal tshuaj hu ua tshuaj uas ua rau kom ntshav txaus rau lub plawv, raws li zoo li txo nws cov pa thov. Cov tshuaj no feem ntau yog siv rau cov nyem los yog kev tiv thaiv ntawm angina sib cem.

Angina - ib tug kab mob uas yog yus muaj los ntawm kev mob los yog tsis xis nyob qab lub breastbone. Feem ntau, cov kev mob ntawm xws li ib tug kab mob no yog manifested mam li nco dheev nyob rau hauv kev nyuaj siab los yog ib ce muaj zog kev nyuaj siab, thiab tom qab noj mov noj. Feem ntau nws muab rau lub caj dab, sab laug sab caj npab, nruab nrab ntawm lub xub pwg tuaj, sab puab tsaig thiab sab laug subscapular cheeb tsam. Tej kaj siab ncus yaj tshaj ¼ teev. Tsis tas li ntawd, lub mob disappears tom qab cessation ntawm ib ce muaj zog los yog tom qab noj anti-anginal tshuaj. Raws li tus tom kawg yog heev feem ntau siv tshuaj "Kordinik". Cov lus qhia rau kev siv, ib tug piav qhia ntawm cov kev npaj thiab nws cov khoom uas hais hauv qab no.

Hauj lwm ntawm lub lam khoom, nws daim ntawv no, muaj pes tsawg leeg thiab packing

Yuav ua li cas daim ntawv no yog xam qhovkev nyob rau hauv lub medicament "Kordinik"? Cov lus qhia nyob rau hauv daim ntawv thov qhia tias cov tshuaj yog muaj nyob rau hauv cov ntsiav tshuaj daim ntawv. Lawv muaj ploskotsilindricheskoy daim ntawv no, muaj ib tug dawb los yog ib tug faint grayish-yellowish xim.

Muaj pes tsawg leeg ntawm cov tshuaj nyob rau hauv kev saib xyuas muaj xws li nicorandil. Raws li koom haum pab Cheebtsam siv qos starch, calcium stearate thiab microcrystalline cellulose.

Cov muag yeeb tshuaj "Kordinik" cov lus qhia rau kev siv yog tau ntim rau hauv ib pawg ntawm cov duab los qhia nkag mus rau hauv contour hlwb.

pharmacology medicament

Yuav ua li cas yog zoo tshaj plaws tshuaj "Kordinik" (ntsiav tshuaj)? Cov lus qhia rau kev siv ntawd hais tias nicorandil muaj antianginal los. Nws yog raws li nyob rau hauv ib tug ua ke nitratopodobnyh zog, raws li zoo raws li lub peev xwm los qhib poov tshuaj raws. Tsaug mus rau yav tas khoom teejtug uas yog cov tshuaj ua rau hyperpolarization ntawm lub cell daim nyias nyias.

Nitratopodobny nyhuv ntawm cov tshuaj no yog ua kom cov ntsiab lus ntawm cyclic guanilmonofosfata intracellularly. Tej pharmacological los txhawb so ntawm tus nqaij thiab tiv thaiv myocardium thaum lub sij hawm ischemia.

Nrog kev xav txog cov hemodynamic los, lawv qhia nyob rau hauv ib tug kuas yuav txo tau ntawm lub post-thiab preload. Muab vasodilation (xim) coronary hlab ntsha nyob rau hauv ischemic myocardium load yog nyoog.

Nicorandil muaj tsis ntxim rau myocardial contractility. Nyob rau hauv tas li ntawd, qhov no tshuaj tsis hloov nyob rau hauv lub plawv dhia. Txawm li cas los, nws thiaj li mauj cov ntshav siab, thiab kuj muaj ib tug nyhuv lig rau lub hlwb cov ntshav khiav tsis zoo hauv cov neeg uas muaj ischemic stroke.

Yuav ua li cas lwm yam khoom xam qhovkev nyob rau hauv cov tshuaj "Kordinik"? Cov lus qhia rau kev siv (tshuaj analogues nram qab no) hais tias nicorandil muaj tsis ntxim rau cov metabolism ntawm piam thaj thiab lipid metabolism. Nws relieves angina, thiab kuj thiaj li mob rau xya feeb tom qab thawj coj nyob rau hauv tus nplaig. Sau kom tiav tshem tawm ntawm tsis xis nyob cai tom qab ¼ teev.

Kinetics ntawm cov nyiaj

Qhov chaw absorbed tshuaj "Kordinik"? Cov lus qhia rau kev siv ntawd hais tias qhov haum ntawm cov tshuaj nyob rau hauv kev saib xyuas los ntawm lub digestive ib ntsuj av. Nws nce mus txog nws cov ncov concentration nyob rau hauv ntshav tom qab 35-60 feeb.

Nicorandil yog tsuas yog me ntsis ua txhua yam rau ntshav proteins. Nws free feem nyob rau hauv cov ntshav yog 75%.

Qhov no tshuaj yog tsis raug intensive metabolism hauv lub siab. Nws yog tas los ntawm ob lub raum nyob rau 50 feeb.

Indications rau kev txais neeg kawm

Thaum twg kuv siv cov tshuaj "Kordinik"? Phau ntawv lub xeev hais tias qhov no txhais tau tias zoo manifests nws tus kheej nrog:

• kev tiv thaiv ntawm tus cwj nrag (ruaj khov) nyob rau hauv ua ke nrog nrog rau lwm cov antianginal tshuaj;
• nyem ntawm angina;
• monotherapy nyob rau hauv cov ntaub ntawv ntawm intolerance BCCI thiab beta-blockers.

Contraindications tau txais

Thaum lub ntsiav tshuaj yuav tsum tsis txhob muab "Kordinik"? Cov lus qhia rau kev siv (txhais hais khoom no muaj nyob hauv qab no) hais txog tej contraindications, xws li:

• cev qhuav dej, cardiogenic poob siab;
• AV-thaiv ntawm peb thiab lub thib ob degree;
• mob myocardial infarction, thiab rau 90 hnub tom qab ntawd;
• tsis ruaj tsis khov angina ;
• Mob hauv lub plawv tsis ua hauj lwm (thib peb los yog thib plaub hauv chav kawm ntawv NYHA haumxeeb kev faib);
• arterial hypotension;
• thaum lub sij hawm cev xeeb tub;
• bradycardia;
• lactation;
• sab laug ventricular insufficiency txo siab filling;
• me muaj hnub nyoog;
• simultaneous siv phosphodiesterase-5 inhibitors (e.g., "sildenafil", "Vardenafil" los yog "tadalafil");
• npau taws me ntsis mus rau yeeb tshuaj.

Ceev faj tej ntsiav tshuaj kws kho rau lub plawv atherosclerosis ntshawv siab, Prinzmetal angina, AV-blockade ntawm cov thawj degree, hypotension, impaired siab muaj nuj nqi thiab lub raum hypovolemia, pulmonary edema, hyperkalemia, lub kaum ntse ntse-kaw glaucoma thiab anemia.

Tshuaj "Kordinik": ntau npaum thiab tswj

Ntsiav tshuaj "Kordinik" yuav tsum tau coj hais lus, tsis hais txog ntawm noj mov.

Cov tshuaj ntawm cov tshuaj yog xaiv ib lub zuj zus. Feem ntau, nws nyob ntawm lub caij thiab qhov ntawm tus kab mob.

Kev pab ntawm angina tshuaj yuav tsum tau noj nyob rau thawj kos npe rau ntawm tus kab mob. Nyob rau hauv cov ntaub ntawv no nws yog muab nyob rau hauv ib tug ntau npaum ntawm 20 mg. Ntsiav tshuaj muab tso nyob rau hauv tus nplaig thiab tuav kom ntev li ntev raws li nws yaj.

Rau kev tiv thaiv ntawm ruaj angina tawm tsam (xws li sij hawm ntev kho) tshuaj no feem ntau yog muab nyob rau hauv ib tug ntau npaum ntawm 10-20 mg peb zaug ib hnub twg.

Qhov siab tshaj plaws ntau npaum ntawm cov tshuaj ib hnub twg yog 80 mg. Mob taub hau thawj zaug koob tshuaj yuav raug muab txo.

phiv

Yuav ua li cas koj yuav tsum paub ua ntej yuav noj cov ntsiav tshuaj "Kordinik"? Cov lus qhia rau kev siv hais tias qhov no neeg sawv cev yuav ua rau kev phiv tshuaj xws li:

• tsis muaj zog, palpitations, mob taub hau, tsis muaj ntshav siab, kiv taub hau;
• tachycardia, tinnitus, "tides" ntawm cov ntshav mus rau lub daim tawv nqaij, insomnia;
• kev tsis haum tshuaj, peripheral edema, xeev siab;
• kev xav ntawm fullness nyob rau hauv lub plab, ntuav, nce ua si ntawm "siab" transaminases, mob plab tsis xis nyob, stomatitis.

Ib tug overdose ntawm tshuaj

Thaum koj tau txais ib tug loj tus naj npawb ntawm cov tshuaj tus neeg mob muaj cov tsos mob xws li tachycardia thiab ntaus cim yuav txo tau nyob rau hauv cov ntshav siab. Nyob rau hauv cov ntaub ntawv no, tus neeg twb ntxuav plab thiab muab tshuab txais charcoal. Tsis tas li ntawd txhawb lub chaw ua hauj lwm ntawm cov hlab plawv system.

Sis nrog lwm yam tshuaj

Antianginal tshuaj nyob rau hauv kev saib xyuas yog kho kom zoo thaum antidepressants, vasodilators, phosphodiesterase-5 inhibitors, antihypertensives, thiab tricyclic antidepressants. Yam muaj tseeb ntawm diuretics, Mao inhibitors, beta-blockers thiab ethanol.

tej tswv yim pom zoo

Txiav cov tshuaj yuav tsum tau maj. Thaum lub sij hawm txoj kev kho yog tsim nyog los saib xyuas ECG thiab arterial ntshav siab, raws li zoo raws li lub ntsiab lus ntawm sodium thiab potassium ions nyob rau hauv cov ntshav. Tsis tas li ntawd, qhov tsawg ntawm cov tshuaj no tej zaum yuav ua rau kom mob arrhythmias.

Analogs thiab txhais ntawm kev yeeb tshuaj, nws nqi

Tam sim no koj paub yuav ua li cas cov tshuaj "Kordinik". Cov lus qhia rau kev siv, cov duab thiab cov thaj chaw ntawm cov tshuaj tau hais saum toj no.

Yuav ua li cas muaj ntau yam xam tau tias yog tshuaj cov nqi? Raws li txoj cai, tus nqi ntawm lub cuab tam 60 ntsiav tshuaj (10 mg) yog 450 rubles. Thaum nyob rau hauv ib co thaj tsam ntawm peb lub teb chaws, qhov no daim duab yuav muab ntau zog los yog, nyob rau hauv tsis tooj, poob.

Nyob rau hauv mob yuav tsum tau rau cov tshuaj yuav tsum tau hloov los ntawm xws li analogs li "Dilasidom", "Korvamin", "Carbochromen", "Korvaton", "Sydnopharm", "Oxycardin", "Reasanz" thiab lwm tus neeg.

Raws li rau lub txhais, lub tsuas tshuaj "Coronel" ntaus nqi mus rau nws.

Tshuaj Xyuas

Hais txog "Kordinik" tshuaj muaj ib tug ntau ntawm cov zoo xyuas. Tau txais kev pab sib ceg hais tias xws li antianginal neeg sawv cev tag nrho daws nrog neeg ua hauj lwm. Txais ntawm lub aforementioned ntsiav tshuaj yog zoo nyob rau hauv txo angina, raws li zoo raws li eliminates lub mob thiab tsis xis nyob qab lub breastbone.

Nyob rau hauv tas li ntawd mus rau lub zoo ntawm cov tshuaj no muaj xws li nws txaus thiab muaj peev xwm mus hloov cov counterparts, thiab cov disadvantages - nqi siab thiab ib tug loj tus naj npawb ntawm cov nyom tshua.