Noj qab haus huv, Npaj
"Itomed": analogues, kev qhia thiab cov tswv yim
"Itomed" - ib tug tshuaj uas muaj feem xyuam rau lub digestive ib ntsuj av. Lub medicament pab hnyuv kom thiab cov laus. Cov tshuaj muaj ib tug muaj zog anti-emetic kev txiav txim.
Lub Cheebtsam ntawm yeeb tshuaj, qhov kev tso tawm daim ntawv
Cov kev npaj no yog ua rau lub hauv paus itopride, muaj nyob rau hauv cov ntsiav tshuaj daim ntawv. Ntau npaum ntawm active tshuaj ib ntsiav tshuaj yog 50 mg. Cov ntsiav tshuaj no muaj nyob rau hauv packs ntawm 40 thiab 100 daim. Koom haum pab Cheebtsam hais acid silicon anhydrous, hypromellose, lactose, makragolom 6000, pob kws starch, magnesium stearate, ciab carnauba, titanium dioxide thiab carmellose. Nyob rau hauv tus neeg mob qhov twg ib tug neeg tsis haum "Itomed", zoo xws li cov npaj yuav xaiv tus kws, tab sis nrog ib tug txawv pes tsawg leeg.
Pharmacological txiav txim, tshuaj
Tshuaj belongs rau antacid enveloping txhais tau tias. Cov tshuaj kuj muaj ib tug anti-rwj nyhuv, nws tsis hloov lub theem ntawm gastrin. Amplification GI kom yog vim kev thaiv kev ntawm dopamine D2-receptors thiab inhibit acetylcholinesterase.
Tshuaj txhawb qhov kev tso tawm ntawm acetylcholine, tiv thaiv nws los ntawm kev puas tsuaj. Antiemetic txiav txim muaj raws li ib tug tshwm sim ntawm cov kev sis raug zoo nrog D2-dopamine receptors, uas muaj nyob rau hauv tus txhais tsam.
Tom qab ua ntawv thov cov ntsiav tshuaj tiav ib koob tshuaj-dependent hluav ntuav, uas yog txhais los ntawm cov tsos ntawm cov "apomorphine".
Siv cov tshuaj muaj ib tug zoo ntxim rau cov chaw ua hauj lwm ntawm lub sab sauv hnyuv ib ntsuj av tau, los ntawm kev siv ntawm no lub cuab tam accelerates pib los ntawm lub plab, ua tsim cov txheej txheem ntawm muab nchuav. Siv es tsis txhob "Itomed" analogues muaj ib tug zoo li cov nyhuv.
Haum ntawm lub medicament mus rau hauv lub mob huam tshwm sim sai heev, bioavailability ntawm kwv yees li 60%. Mus rau yeeb tshuaj concentration rau hauv cov ntshav los ua lub siab tshaj plaws, yuav tsum tau 30 mus rau 45 feeb. Lub tsub zuj zuj ntawm cov nyiaj nyob rau hauv lub cev yog tsawg heev. Kev sib txuas lus ntawm cov nqaijrog: albumin - 96% alpha acid glycoprotein - txog 15%.
Tshuaj yog zoo faib nyob rau hauv cov ntaub so ntswg, nws nkag mus rau hauv me me hnyuv, mob plab, adrenal qog, daim siab, ob lub raum. "Itomed" yog pom nyob rau hauv nyob tus yeees ntawm lub mis mis nyuj, ib tug me me npaum li cas ntawm nws yog nyob rau hauv cov leeg nrob qaum thiab lub hlwb. Metabolic dab tshwm sim nyob rau hauv lub siab, ob lub raum tso tawm kom pom kev kho, ib nrab tshem tawm tshwm sim tsis pub dhau rau lub sij hawm, thaum ntev Trimethylaminuria.
Indications, contraindications
"Itomed" analogs raug thaum uas tsim nyog los kho tus mob nonulcer dyspepsia, nrog mob gastritis zoo. Cov tshuaj no yog qhia rau mob plab distension, xeev siab, ntuav muaj nyob nrog txoj kev loj hlob, kub siab thiab mob nyob rau hauv lub plab. Yog hais tias cov neeg mob muaj mob plab tsis xis nyob, tshwj xeeb tshaj yog nyob rau hauv lub epigastric cheeb tsam, kuj tau xaiv "Itomed", nws lub hom phiaj yog tau thiab anorexia.
Ntsiav tshuaj tsis tau npau taws me ntsis rau lawv lub Cheebtsam, thaum los ntshav nyob rau hauv cov hnyuv thiab plab. Contraindications kuj muaj xws li cov glucose-galactose malabsorption, lactose intolerance, tsis muaj lactase. Tsis txhob siv cov tshuaj nyob rau hauv cov me nyuam nyob rau hauv kaum xyoo ntawm lub hnub nyoog, cev xeeb tub thiab lactating cov poj niam. Analogs "Itomeda" yuav los piv nrog rau cov perforations ntawm cov hnyuv thiab cov neeg kho tshuab dab tsi thaiv.
Cov tej yam kev mob ntawm kev kho mob yuav tsum tau cov neeg mob uas noj m-cholinomimetics thiab inhibitors holinoesterazy, cov neeg laus cov neeg mob uas mob ntawm lub raum thiab lub siab.
Cov kev siv tshuaj, ntau npaum
Cov tshuaj noj txhua hnub kom txog rau thaum zaub mov noj nyob rau hauv ib koob tshuaj ntawm 150 mg, i.e. yuav tsum tau triple tshuaj, 50 mg ib lub sij hawm. Cov laus koob tshuaj txo. Nyob rau hauv tus neeg mob qhov twg tsis muaj peev xwm mus coj ib tug ntsiav tshuaj nyob rau hauv lub sij hawm, txuas ntxiv mus siv ntawm cov nyiaj yuav tsum tau nqa tawm, tsom kwm sib npaug zos Team sib. Koj muaj peev xwm tsis ob npaug rau koob tshuaj.
phiv
tshwm sim muaj tshwm sim tom qab tau txais txhais tau tias "Itomed". analogs Guide qhia rau taw, yog hais tias nws tsis haum cov tshuaj rau tus neeg mob. Undesired tshua yuav tsim los ntawm cov digestive, lub paj hlwb thiab endocrine systems. Ib txhia neeg tsim kev tsis haum tshuaj, ib ntus hloov kuaj ntsuas. Tau disruptions rau lub cev thiab kev ua me nyuam lub nruab. Peev xwm cuam tshuam lub metabolism thiab daim tawv nqaij qhov chaw mob tshwm sim. Muaj kuj yog sab los muaj kev hloov nyob rau hauv lub hematopoietic system.
Overdosing yog tshem tawm los ntawm pais plab lavage thiab kev siv ntawm symptomatic txoj kev kho. Nyob rau hauv xws li mob, ntxiv kev kho mob yuav raug muab tso es tsis txhob txhais tau tias "Itomed" counterparts.
ceev faj
Yog hais tias tus neeg mob yog muaj nyob tej yam tshwm sim ntawm gynecomastia thiab galactorrhea, txoj kev kho los mus ib ntus nres los yog hloov nws mus rau lwm cov tshuaj. Siv "Itomeda" nyob rau hauv cov kev kho mob ntawm biliary mob npuas paug (thawj) yuav ua tau kom dua decompensated mob npuas paug yog ib lub xeev disappears nthawv tom qab tshuaj ntsoos ntsoos. Tsim lub sij hawm mus muab ib qho tseem ceeb ua hauj lwm, nyob rau hauv uas yuav tsum tau mus kom cov xim thiab ceev ceev psychomotor tshua thaum lub sij hawm kev kho mob muaj tshuaj "Itomed". Analogs, hloov tau raug xaiv ua ke nrog ib tug kws, yog tias tsim nyog.
"Itomed" tau nyob rau hauv ib tug ntau ceev ceev haum ntawm lwm yam tshuaj. Cov nyhuv ntawm cov tshuaj yog tsis degraded raws li ib tug tshwm sim uas tau txais txhais tau tias, uas txiav txim yog qhia rau kom txhob muaj pais plab acidity. Nyhuv yog tsawg pronounced, thaum lub sij hawm daim ntawv thov ntawm cov medicament nrog m-holinoblokatorami, ua ke nrog kev npaj nrog inhibitors holineserazy, m-holinomimetikami muaj zog cov nyhuv ntawm kev noj cov tshuaj "Itomed". Analogs yuav manifest nws tus kheej txawv nyob rau hauv uas zoo sib xws tus neeg mob.
analogs xyuas
Thaum nws yog tsim nyog los hloov cov tshuaj, qhov no qhov teeb meem yog tham nrog ib tug tshwj xeeb. Feem ntau, raws li ib tug kev hloov rau cov kws kho mob muab cov tshuaj "itopride" thiab kev coj cwj pwm kev kho mob nrog "Itopra" npaj los yog "Ganaton". Cov analogs "Itomeda" yog muaj li ntawm cov tib yam kom nquag plias khoom sib ua zaub mov.
Muab thiab domestic hloov cov tshuaj. Muaj cov cuab yeej rau "Itomed" analogues (Russia), xws li "Tseruglan", "Gastrika-GF".
Txawm tias muaj tseeb hais tias "Itomedom" cov neeg mob yuav kho rau ib ntev lub sij hawm, saib xyuas nws daim ntawv thov yog tsis txaus. Feem ntau noj cov tshuaj tsis pub dhau rau mus rau yim lub lim piam ua rau cov tshem tawm ntawm flatulence, kub siab minimizes ua rau lub disappearance ntawm lub ntiajteb txawj nqus nyob rau hauv lub plab thiab lub rov tshwm sim ntawm qab los noj mov. Cov neeg mob nrhiav zoo tshuaj rau cem quav thiab mob cov ntaub ntawv. Xyuas qhia ib tug zoo tolerability ntawm cov tshuaj thiab tsis muaj mob loj cov txheej xwm. Feem ntau muaj raws plab, muaj mob taub hau thiab mob nyob rau hauv lub plab mog. Xyuas qhia tias cov tshuaj yuav ua tau kom amenorrhea. Txawm li cas los, tag nrho cov ib lub zuj zus thiab kev txiav txim "Itomeda" tej zaum yuav sib txawv, uas muaj tsis muaj teeb meem loj txim, kev kho mob yuav tsum tau kho los ntawm ib tus kws kho mob.
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