"Formetin": cov lus qhia rau kev siv, tiag tiag

Tam sim no peb pom ntau tus neeg muaj ntshav qab zib thiab cov teeb meem ntawm rog hom. Muaj ntau cov tshuaj muaj nyob rau hauv kev kho mob ntawm cov ailments. Ib tug ntawm lawv yog ib tug kho "Formetin". Nws salient nta yuav tau piav nyob rau hauv no tsab xov xwm.

kws qeb

"Formetin" cov lus qhia rau kev siv uas yog qhia nyob rau hauv no tsab xov xwm, yog ib tug biguanide hypoglycemic tshuaj pab pawg neeg.

Hauj lwm ntawm lub muaj pes tsawg leeg thiab tso tawm daim ntawv

Nyob rau hauv ib qho ntawm nws cov ntsiav tshuaj:

Qhov tshuaj "Formetin" nyob rau hauv cov hlwv 100, 60 los yog 30 ntsiav tshuaj.
Xim Dawb ntsiav tshuaj thiab ntau npaum daim ntawv nyob rau hauv lub hauv paus khoom. Nyob rau ntawm 500 mg ploskotsilindricheskoy lawv muaj ib tug yeej zoo nrog lub cim thiab chamfered. Tsis tas li ntawd ntau npaum ntawm 1000 mg los yog 850 mg muaj "Formetin". Cov ntsiav tshuaj nyob rau hauv cov ntaub ntawv no, convex thiab dawb. Lawv yog ib tug-ib tog kev pheej hmoo.

pharmacodynamics

Metformin ( "Formetin") slows gluconeogenesis ntws nyob rau hauv lub siab, thiab yog li muaj ib tug txo nyob rau hauv glycogen khw muag khoom noj nws. Qhov cuab yeej no muaj txhawb rau cov teeb meem ntawm haum los ntawm lub plab hnyuv qabzib, txhim khu qhov kev tshem tawm ntawm cov ntshav qab zib theem ntawm lub system. Qhov no yuav tsub cov lus teb ntawm ntaub so ntswg rau insulin tsis muaj cuam tshuam zus tau tej cov nws endocrine feem ntawm lub pancreas B-hlwb, bypassing hypoglycemic cov tshuaj tiv thaiv, vim nws yog tsis tshuab txais zus tau tej cov hais tias substance.

Tshuaj "Formetin" xyuas uas tham txog nws cov hauj lwm zoo, thiaj li tus nqi ntawm cov ntshav nyob rau hauv lub "phem" cov roj cholesterol thiab triglycerides. Cov ntsiab lus ntawm kev kub ceev lipoproteins no tsub kom mus 20-30%. Nrog rau cov ineffectiveness ntawm noj cov zaub mov tshuaj "Formetin" cov lus qhia rau kev siv uas yog tau piav nyob rau hauv no tsab xov xwm yuav pab tau txo thiab / los yog tswj tus neeg mob hnyav. Qhov no tshwm sim vim cov oxidation ntawm zib los ntawm cov pa-dawb thiab txo qab los noj mov. Tsis tas li ntawd nws blunted cov ntaub so ntswg plasminogen kom cov txheej txheem los ntawm sawv nyob rau hauv nws inhibitor, nyob rau lub hemostatic nyhuv zoo nkaus li.

tshuaj

Assimilation Metformin pib nyob rau hauv lub hnyuv ib ntsuj av. Qhov siab tshaj plaws kom muaj nuj nqis ntawm tej yam khoom uas nyob rau hauv cov ntshav yog hais txog 2.5 teev tom qab daim ntawv thov ntawm tus nqi ntawm haum tsev tshuaj - 50-60%. Suction zoo ntawm cov tshuaj nyob rau hauv lub cev muaj feem xyuam rau cov kev twb kev txuas ntawm lub active tshuaj thiab cov protein nyob rau hauv cov ntshav. Nyob rau hauv cov ntsiav tshuaj "Formetina" tsis muaj kev twb kev txuas rau ntshav proteins. Nws hais txog nws cov hauj lwm zoo. Txij li thaum tus me tus losis tswvyim dabtsi zoo tshaj, cov tshuaj yog zoo dua absorbed. Deposition yog lub raum, lub siab, nyob rau hauv tej nqaij, nyob rau hauv lub muaj qaub ncaug. Nyob rau hauv lub cev, Metformin tseem unchanged. Nws tom qab tas los ntawm ob lub raum. Yog li ntawd, nyob rau hauv cov ntaub ntawv ntawm ua txhaum ntawm lawv ua hauj lwm muaj cai txuam nrog. Lom ib nrab-lub neej yog 1.5-4.5 teev.

destiny

Tshuaj "Formetin" yog siv rau cov kev kho mob ntawm tej yam pawg ntawm cov kab mob. Namely, nyob rau hauv lub xub ntiag ntawm hom II mob ntshav qab zib, nrog rog neeg uas muaj tham thaum cov khoom noj tsis pab kom cov ntshav qab zib theem qub, txawm nyob rau hauv ua ke nrog nrog ib tug sulfonylurea. Tsis tas li ntawd zoo yog cov "Formetin" rau poob phaus.

Yuav ua li cas tau?

Cov koob ntawm cov kws kho mob txhais tau hais tias xaiv, raws li nyob rau hauv tus nqi ntawm zib nyob rau hauv cov ntshav. Ncauj thawj coj yog tsim nyog los siv tom qab ib tug noj mov, haus nrog tus nqi ntawm cov kua thiab raug lead lom rau cov ntsiav tshuaj machining. Raws li twb hais saum toj no, ntau npaum yog tshuaj nyob rau ntawm lub ntsiab lus ntawm zib nyob rau hauv cov ntshav. Nws pib nrog ib tug tsawg kawg nkaus tus nqi - 0.5 g los yog 0.85 g ib hnub twg. Ob hnub tom qab pib kho mob nrog cov tshuaj no tau ib tug khov kho cov ntsiab lus ntawm Metformin nyob rau hauv cov ntshav. Optionally, maj mam ntxiv kom cov koob tshuaj kom txog thaum ib tug nqi siab tshaj plaws. Nws yog sib npaug rau 3 grams.

Txij li thaum cov neeg laus feem ntau pom txoj kev loj hlob ntawm lactic acidosis, rau lawv rau theem ntawm cov nyiaj pab ntau tshaj txhua hnub koob tshuaj 1 g nqi ntawm cov tshuaj no kuj txo nyob rau hauv kev ua txhaum ntawm metabolism, nyob rau hauv thiaj li yuav tiv thaiv kom txhob ib tug tsis haum cov tshuaj tiv thaiv, uas manifests nws tus kheej nyob rau hauv daim ntawv ntawm daim tawv nqaij ua pob ua xyua, thiab lwm yam tau phiv cov txheej xwm, uas yuav tsum tau teev hauv qab no.

Contraindications

Nyob rau hauv no hais txog, muaj ntau ntau yam nuances. Tshuaj "Formetin" cov lus qhia rau kev siv uas yog qhia nyob rau hauv phau ntawv no, yog ua rau hauv lub xub ntiag ntawm:

• Ntshav qab zib ketoacidosis, precoma, coma.
• Loj lus raum functionality.
• Plawv thiab ua pa tsis ua hauj lwm.
• Mob theem ntawm myocardial infarction.
• Lub cev qhuav dej.
• Mob alcoholism thiab lwm yam tej yam kev mob uas tej zaum yuav ua rau kom lub manifestation ntawm cov lactic acidosis.
• Mob stroke.
• Cev xeeb tub thiab pub niam mis.
• Npau taws me ntsis rau qhov no srudstvu.
• Phais loj los yog raug mob, thaum insulin yog tsa.
• Loj kis kab mob.
• Kev mob ntawm lub siab.
• Mob cawv lom.
• Lactic acidosis (xws li keeb kwm).
• Hypocaloric noj cov zaub mov (tsawg tshaj li 1000 kcal. Ib hnub).
• Adioizotopnyh los yog radiographic kev tshawb fawb, tus thawj coj ntawm tshuaj iodide hom.

Nws kuj tsis pom zoo kom siv cov tshuaj "Formetin" neeg tshaj rau caum xyoo, ua lub cev demanding ua hauj lwm. Txij li thaum nyob rau hauv cov ntaub ntawv no, lawv muaj kev raug mob ntawm cov lactic acidosis.

sab nyhuv

Cov tshwm sim ntawm tej tsis kaj siab tsos mob li "nws yog xim hlau" saj nyob rau hauv lub qhov ncauj, ntuav, xeev siab, raws plab, flatulence, tsis muaj qab los noj mov yuav tsum tau discontinuation ntawm kev siv kev kho mob thiab tam sim ntawd xa mus rau ib tug tshwj xeeb. Long-term siv ntawm cov tshuaj ua rau ib tug ntxaug los yog tiav cessation ntawm tsawg ntawm cov vitamin B _12, uas ua rau yus lub hnab khib nyob rau hauv lub cev ntawm lub yav tas, ua rau vitamin raug. Nyob rau hauv tsawg tus neeg mob, tsim rov qab - megaloblastic Lub _12-scarce anemia. Yog hais tias tsis muab tshuaj tau hypoglycemia. Tej zaum koj kuj muaj kev tsis haum tshuaj loj xws li daim tawv nqaij ua pob liab vog. Yog li ntawd, cov tshuaj "Formetin" xyuas uas nyob rau nws tsim nyog nyob rau hauv kev siv ntau yam, yuav tsum tau tsa nkaus xwb los ntawm lub mus kawm tus kws kho mob.

ceev faj

Ib qho tseem ceeb feature txhais kev khaws cia cov yooj yim tshuaj "Formetina" nyob rau hauv lub cev thiab ib tug rau txim ntawm no.

Yuav kom tiv thaiv txuam nrog ntawm lactic acidosis thiab kev tiv thaiv ntawm Metformin, nws yog tsim nyog los saib xyuas cov ntsuas ntawm lub raum muaj nuj nqi thiab rau kev ntsuam xyuas los mus txiav txim cov ntsiab lus ntawm lactic acid nyob rau hauv lub cev tsawg kawg yog 2 lub sij hawm ib xyoos twg. Tsis tas li ntawd, Yog hais tias koj muaj mob nyob rau hauv cov nqaij yuav tsum tau xeem.

Cov nyhuv ntawm hais tias cov tshuaj nyob rau hauv lub peev xwm tsav mechanisms thiab tsav tsheb

Nyob rau hauv cov ntaub ntawv no, raws li muaj tej yam nuances. Impact "Formetina 'muaj peev xwm ua hauj lwm machinery thiab thauj yuav siv sij hawm qhov chaw tsuas yog siv nyob rau hauv ua ke nrog tshuaj rau cov ua hauj lwm dab uas yuav tsum tau cov kev ceev ntawm cov lus teb thiab muaj zog concentration. Nws yog ib qho tseem ceeb kom paub.

Daim ntawv thov ntawm cev xeeb tub thiab pub niam mis

Kev npaj "Formetin", cov lus qhia rau kev siv ntawm uas yog tau piav no, muaj teebmeem nyob rau lub fetus qeb «B» los ntawm FDA. Thaum lub sij hawm uas cev xeeb tub yuav tau txais cov nyiaj no. Txawm li cas los, nws siv yuav ua tau tsuas nyob rau hauv tej yam mob. Namely - thaum yuav tsum tau los ntawm no txoj kev kho yuav tshaj cov nyob rau ntawm lub peev xwm uas yuav muaj rau lub fetus. Kev thiab cov ntaub ntawv tshawb fawb nyob rau kev siv ntawm ib lub cuab tam xws li ib tug yeeb tshuaj "Formetin" twb tau soj xyuas thaum lub sij hawm lub sij hawm uas cev xeeb tub. Thaum lub sij hawm ntawm kev kho mob yuav tsum tsis txhob pub niam mis. Nyob rau hauv txhua rooj plaub, koj yuav tsum sab laj nrog ib tug tsim nyog tus kws kho mob.

tshuaj cov kev sib tshuam

Metformin tsub kom cov theem ntawm cov ntshav qab zib. Qhov no yog tshwj xeeb yog tshwm nrog lub simultaneous txais tos ntawm ib tug uas tsis yog-tshuaj anti-inflammatory siv tshuaj, sulfonylurea derivatives thiab clofibrate, monoamine oxidase inhibitors, acarbose, insulin, oxytetracycline, cyclophosphamide, inhibitors ntawm angiotensin converting enzyme blockers thiab hom.

Thaum ua ntawv thov ua ke nrog endocrine tshuaj (qhov ncauj contraceptives, corticosteroids, sympathomimetics epinephrine, thyroid caj pas cov tshuaj hormones, glucagon, thiazide thiab "voj" diuretics, phenothiazine derivatives, nicotinic acid derivatives) tej zaum yuav Metformin hypoglycemic braking txheej txheem.

Nrog ib tug ua ke ntawm ib lub cuab tam xws li ib tug yeeb tshuaj "Formetin" nrog "Tsimidinom" "nifedipine" loj hlob kev uas yuav lactic acidosis, Metformin inhibiting lub feem ntawm lub cev. Tej cai nyob rau hauv lub chaw ua hauj lwm ntawm lub dej khoom, nyob rau hauv Vol. H. Nyob rau hauv nyob tus yeees ntawm cov tshuaj.

Cationic agents (quinidine, amiloride, digoxin, procainamide, morphine, quinine, vancomycin, ranitidine, triamterene) tsim nyob rau hauv lub tubules, vying rau cov thauj system thiab ntev-lub sij hawm kev kho mob tej zaum yuav ua rau kom cov theem ntawm cov tshuaj concentration mus rau 60%.

overdose

Overdose "Formetinom" cai thaum noj 0.85 grams tauj ib hnub thiab ntxias lactic acidosis. Tsis tas li ntawd, ib tug siab cov ntsiab lus ntawm Metformin vim lub raum tsis ua hauj lwm.

Early cov tsos mob ntawm lactic acidosis yog cov tsis muaj zog ntawm lub tag nrho lub cev, tsam plab, tsis tshua muaj lub cev kub, mob nyob rau hauv lub plab thiab cov nqaij ntshiv, txo cov ntshav siab, reflex bradyarrhythmia. Nyob rau hauv tej rooj plaub, muaj feem ntau ces ua pa mob, kiv taub hau, thiab, raws li ib tug tsim nyog tau, yog txoj kev loj hlob ntawm coma.

Thaum lub slightest cov tsos mob ntawm overdose yuav tsum tsis txhob siv cov tshuaj thiab tham ib tug kws kho mob kom paub meej tias qhov mob ntawm lactic acidosis. Rau kev tshem tawm ntawm lub active tshuaj ntawm tus neeg saib xyuas thiab lactic acid los ntawm ib tug kab mob yuav hemodialysis thaum uas tig mus nrog symptomatic kev kho mob.

"Formetin": counterparts

Muaj ntau ntau ntawm cov kev pab ntawm no hom. Analogues "Formetina" protrude formulations uas muaj nyob rau hauv nws muaj pes tsawg leeg raws li ib tug lub ntsiab tivthaiv ntawm Metformin hydrochloride. Ib tug piv txwv yog lub tshuaj ntawm Lavxias teb sab producers, "Vero Metformin," "Gliformin", "Metformin", "Metformin-Richter", thiab txawv teb chaws - "Glucophage", "Glucophage" thiab "Glyukofazh Ntev" (Fabkis), "Lanzherin "(Slovakia)" Metfogamma "uas ua noj tshuaj npaum cas ntawm active tshuaj ntawm 0,100, 0,500 thiab 0,850 g (lub teb chaws Yelemees).

Tej yam kev mob thiab cov nqe lus

Nyob rau hauv no hais txog, muaj ntau yam tej yam kev mob. Kev npaj "Formetin" yog ib tug muaj zog, li ntawd, nws yog tso tawm tsuas yog cov tshuaj thiab yuav tsum tau cia rau ntawm chav tsev kub, tawm ntawm ncav cuag ntawm cov me nyuam thiab tshav ntuj qhov chaw. Txee lub neej nws - 2 xyoo.

nqi ntawm

Qhov nruab nrab nqi rau cov tshuaj "Formetin" yog teem nyob rau hauv lub tshuaj los ntawm 59 rubles. 0.5 g ntawm cov hlwv, 133 rubles. ntawm 0.85 g thiab 232 rubles. tshaj 1 xyoo

xaus

Tag nrho cov foregoing muaj xws li ib tug ntau ntawm ntaub ntawv uas pab. Tom qab nyeem ntawv no tsab xov xwm, txhua leej txhua tus yuav tsum tau mus nrhiav ib lo lus teb rau lo lus nug ntawm yuav ua li cas coj 'Formetin "thiab nws muaj zog.