"Eufillin": xyuas. "Eufillin": qhov tshwm sim rau kev siv

Tus yeeb tshuaj "Eufillin" yog dab tsi? Cov lus hais txog cov tshuaj no, nws cov kev taw qhia, cov qauv ntawm daim ntawv thov thiab cov kev mob tshwm sim los ntawm peb yuav muab nyob rau hauv tsab xov xwm no. Koj yuav kawm txog daim ntawv uas siv cov tshuaj no thiab muag nws cov nqi.

Cov lus qhia dav dav

Cov tshuaj "Eufillin", xyuas txog cov uas muaj ntau hom neeg, yog tshuaj siv roj ntsha. Cov tshuaj no yog rau pawg neeg xanthin. Nws tuaj yeem muas tau yuav luag txhua lub chaw muag tshuaj, tab sis, nws yog ntshaw kom siv cov yeeb tshuaj no rau cov hom phiaj kho mob nkaus xwb raws li tus kws kho mob hais.

Cov ntaub ntawv thiab cov kab txawv ntawm cov tshuaj

Tam sim no, cov tshuaj muaj peev xwm yuav tau nyob rau hauv ob hom sib txawv, uas yog:

• Hauv cov ntsiav tshuaj uas muaj 150 mg ntawm cov khoom muaj nyob rau hauv, xws li aminophylline. Hauv qhov muag ntawm cov tshuaj no tuaj nyob rau hauv ib daim duab rau ib pob ntawm 50, 10, 30 lossis 20 daim.
• Cov tshuaj "Eufillin" hauv ampoules. Ib tug 2.4% daws rau kev txhaj tshuaj (1 ml) muaj 24 mg ntawm aminophylline.

Hais txog hom tshuaj twg los thov kev kho mob ntawm tus kab mob no, koj yuav tsum tau tsuas yog tus kws kho mob tuaj.

Cov khoom ntawm kev npaj

Raws li tau hais los saum no, cov tshuaj "Eufillin" hauv ampoules lossis cov ntsiav tshuaj muaj cov khoom tseem ceeb - aminophylline. Lawm, qhov no yog qhov sib tov uas muaj 80% theophylline thiab 20% ethylenediamine. Qhov no composition zoo heev facilitates lub solubility ntawm yeeb tshuaj, thiab tseem significantly kho nws cov nqus.

Cov tshuaj yeeb "Eufillin" uas tau xaiv los ntawm cov kws kho mob? Lub cim ntawm qhov kev kho no yog vim nws lub zog ntawm lub bronchi. Yog li, lub medicament "Eufillin" yog tau so lub tus nqaij ntawm hais tias lub cev thiab tshem tawm ntswj tshwm sim los rau lawv. Nws kuj zoo txhim kho txoj haujlwm ntawm epithelial cilia ntawm txoj hlab ntsws, thiab kuj ua rau kev txo ntawm intercostal, diaphragmatic thiab lwm cov leeg nqaij.

Dab tsi yog qhov peculiarity ntawm yeeb tshuaj "Eufillin"? Cov neeg mob xyuas cov lus hais tias cov tshuaj no muaj peev xwm tsim cov kab mob hauv lub medulla oblongata, nrog rau kev txhim kho cov kev mob ntsig txog lub cev, oxygenate cov ntshav thiab txo cov pa roj carbon dioxide cov ntsiab lus hauv nws, uas yog, ua rau lub cev tsis ua pa.

Ntsiab cai ntawm kev txiav txim ntawm cov tshuaj

Lub tswv yim ntawm tus neeg sawv cev yog tias nws tsis cuam tshuam cov phosphodiesterase enzyme, uas ua rau lub pob txig ntawm adenosine monophosphate nyob rau hauv cov ntaub so ntswg, as Well as kom cov calcium ions mus rau hauv lub hlwb lub luag hauj lwm rau cov leeg contraction, uas kuj relaxes tus musculature du ntawm bronchi.

Nws kuj tseem yuav tsum tau sau tseg tias cov tshuaj "Eufillin" (ampoules, ntsiav tshuaj) muaj peev xwm txhawb txoj kev ua kom lub plawv, vim muaj zog ntau zaus thiab lub zog ntawm lub cev nqaij me. Nws txo qis ntawm cov hlab ntsha ntawm lub nruab nrog cev xws li lub raum, lub hlwb thiab tawv nqaij.

Muab ib lub txiaj ntsim zoo rau ntawm cov phab ntsa ntawm cov leeg hauv lub voj voog me me ntawm cov ntshav, cov tshuaj no pab txo kom txhob muaj siab hauv nws. Kev siv cov tshuaj "Eufillin" kuj ua rau lub cev muaj zog ntawm ob lub raum. Vim qhov no, tsim thiab, raws li, excretion ntawm zis considerably nce. Txhais tau tias slows platelet aggregation. Ib tug yuav pab tsis tau hais tias "Eufillin" ua rau cov ntshav liab tuaj yeem ua kom puas tsuaj. Hauv lwm lo lus, nws ho ua rau cov kev mob rheological ntawm cov ntshav txhim kho.

Nws kuj paub txog cov tshuaj tocolytic ntawm cov tshuaj no rau ntawm lub tsev menyuam. Nws kuj yog peev xwm ntawm nce lub acidity ntawm pais plab kua txiv.

Kev nqus thiab tshem tawm

Medicinal khoom "Eufillin" - los ntawm seb nws yog siv los ntawm cov neeg mob? Ua ntej teb lo lus nug posed, nws yuav tsum tau hais tias qhov tshuaj no yog absorbed haum zoo los ntawm lub plab system. Nws bioavailability nce mus txog 100%, tab sis nrog rau kev ua ke nrog cov khoom noj khoom haus, kev nqus ntawm cov tshuaj muaj peev xwm qeeb qeeb.

Cov tshuaj no ua rau cov mis niam thiab tsis tuaj yeem nres ua ntej qhov tsis sib haum xeeb. Metabolism yog txhais tau tias nyob hauv lub siab xwb. Nws raug tshem tawm ntawm tib neeg lub cev yog los ntawm ob lub raum.

Tshuaj "Eufillin": qhia txog kev siv

Cov tshuaj siv "Eufillin" yog tus kws kho mob ua rau cov neeg mob nyhav (bronchitis), rau cov neeg mob ntsws asthma ntawm kev nyuaj siab thiab ua lwm yam tshuaj, nrog rau kev mob ntsws asthmatic (tsuas yog kev sib xyaw ua ke), lub plawv tsis ua hauj lwm, kev kho mob stroke, thiab Xws li lwm cov kev mob ntawm lub paj hlwb, angina pectoris, Cheyne-Stokes respiratory, pulmonary emphysema, pulmonary edema thiab lwm yam txawv txav uas yog txuam nrog cov kev ua ub no congestive. Tswv yim los ntawm cov neeg mob medicament "Eufillin" (tshuaj rau tso dej tshuaj thiab cov ntsiav tshuaj) zoo txo lub siab thaum lub sij hawm ib tug hypertensive ntsoog. Nws yog siv los kho apnea ntawm cov me nyuam yug tshiab, uas yog, thaum lub caij nyoog ua pa ntsaws (rau 15 feeb), thiab muaj kev tsis zoo los ntawm kev mob bradycardia thiab cyanosis.

Contraindications siv

Cov tshuaj "Eufillin" (qhia txog kev siv cov tshuaj no muaj ntau qhov tshwj tsis yog) muaj ntau cov tshuaj tiv thaiv.

Yog li, cov tshuaj uas tau hais no tsis tshua pom zoo rau kev kho mob yog tias koj muaj tsawg kawg yog ib qho ntawm cov xwm txheej hauv qab no:

• Qhov tseem ceeb tshaj rau ib qho ntawm cov tshuaj yeeb dej caw, nrog rau cov keeb los ntawm xanthine (pentoxifylline, caffeine, theobromine);
• Arterial hypertension;
• Arrhythmia;
• Myocardial infarction;
• Pathology ntawm myocardium;
• Lub plawv tsis ua hauj lwm;
• Lub hauv siab duodenum lossis lub plab;
• Mob ntev lossis mob hnyav (tshwj xeeb tshaj yog nyob rau theem ntawm kev sib zog) gastritis;
• Zawv plab;
• Adenoma ntawm prostate;
• Pulmonary plawv;
• Cystic fibrosis mastopathy;
• Hypoxemia;
• Alcoholism;
• Hyperthyroidism;
• Ua npaws;
• Kab mob ntawm lub qhov quav;
• Cov kab mob hnoos hawb pob;
• Impaired daim siab ua haujlwm;
• Kev mob raum tsis zoo los sis mob tsis zoo;
• Edematous Syndrome;
• Pub niam mis;
• Hypernatremia;
• Cev xeeb tub.

Lus qhia rau kev siv

Nyob rau hauv daim ntawv ntawm ib tug daws, xws li ib tug yeeb tshuaj yog muab intramuscularly los yog intravenously. Nws yuav tsum tau tshwj xeeb tshaj yog qhia tias kev siv cov tshuaj no yog siv thaum muaj xwm ceev thiab muaj xwm ceev. Nyob rau hauv cov ntaub ntawv no, qhov ntau npaum li cas ntawm cov tshuaj yuav tsum tau muab xam ib tus zuj zus thiab nyob ntawm seb tus kabmob hauv cov neeg sib txawv, qhov mob hnyav ntawm tus neeg mob thiab qhov hnyav ntawm nws lub cev.

Cov kev cai dab tsi yuav tsum paub tias yuav tsum txhaj cov tshuaj intravenously rau "Eufillin"? Ib tug dropper nrog ib tug yeeb tshuaj yuav tsum muab tso rau qhov zoo heev, thiab tseem ceeb tshaj plaws - maj mam.

Raws li cov lus qhia, rau cov neeg laus thaum muaj xwm ceev, qhov tshuaj ntawm cov tshuaj no yog xaiv ntawm tus nqi ntawm 6 mg rau 1 kg ntawm qhov hnyav. Ua li no, cov tshuaj yuav tsum tau diluted rau hauv 20 ml ntawm saline "Sodium Chloride" thiab hno cov tshuaj intravenously. Cov kev txhaj tshuaj yog qeeb heev (rau 5-8 feeb).

Yog hais tias tus neeg mob muaj tus kab mob asthmatic, ces nws tau sau ib qho kev kis mus rau ntawm 720 lossis 750 mg ntawm cov tshuaj. Lub sijhawm ntev li ntawm txoj kev kho yuav tsum tsis pub tshaj 14 hnub.

Ua kom yooj yim rau tus neeg mob qhov mob hauv obstructive mob ntsws (tshwj xeeb tshaj yog nyob rau cov mob hnyav), kev khiav dej num ntawm yeeb tshuaj pib nrog 5-6 mg ntawm 1 mg ntawm tus neeg mob qhov hnyav. Yog tias tsim nyog, nws tuaj yeem tau nce. Txawm li cas los, qhov no yuav tsum ua kom zoo heev, tswj cov duab ntawm cov ntshav.

Raws li cov ntsiav tshuaj, nyob rau hauv daim ntawv no, "Eufillin" yog sau rau 0.15 g tom qab noj mov ib zaug los yog ib hnub ib zaug. Lub sijhawm ntawm kev tuaj yeem tuaj yeem xeem tau ob peb hnub lossis ib hlis.

Hauv apnea ntawm cov me nyuam yug tshiab, thawj zaug ntawm cov tshuaj no yog 5 mg rau 1 kg ntawm qhov hnyav ib hnub (hauv 2 faib koob). Nyob rau hauv cov ntaub ntawv no, cov tshuaj yog muab los ntawm nasogastric raj. Tom qab txhim kho, koj yuav tsum hloov mus rau txoj kev kho tu tsev (2 mg rau 1 kg ntawm ib hnub nyob rau hauv 2 muab faib koob). Duration ntawm kev kho mob ntawm tus kab mob yuav ua tau ob peb lub lis piam los yog lub hlis.

Rau cov me nyuam yaus thiab cov laus dua, cov tshuaj yuav tsum tau ua raws li qhov qhia tau thiab qhov mob hnyav. Qhov tshuaj txhua hnub nws txawv ntawm 6-15 mg rau 1 kg ntawm lub cev qhov hnyav.

Nthuav dej ntawm "Eufillin"

Cov tshuaj yog indispensable nyob rau hauv obstructive bronchitis. Qhov no yog vim lub fact tias nws facilitates excretion ntawm phlegm thiab extends lub vessels ntawm bronchi zoo. Hauv chav kho mob chav kho mob, uas muaj nyob hauv txhua lub tsev kuaj mob, txoj kev nqus dej yog siv los ntawm ntau qhov chaw ntawm qhov chaw no. Yog li, 10 ampoules ntawm "Dimedrol", zoo li 500 ml ntawm dej, yuav tsum tau siv rau 3 ampoules ntawm cov tshuaj. Thaum siv los kho ib qho compressor Cav Tshuab Pa Tshuaj, ces qhov no ntau npaum yuav tsawg npaum li cas, txawm hais tias tus proportions yuav tsum tau khaws cia.

Ua ntej koj dilute thiab siv "Eufillin" rau kev nqhis dej ntawm menyuam, koj yuav tsum nrog tus kws kho menyuam yaus ib txwm nrog.

Tej kev mob tshwm sim

Raws li cov kev txheeb xyuas, "Eufillin" tshuaj yuav ua rau tej kev phiv los raws li kiv taub hau, insomnia, ntev li nyob tsis tswm, qhov mob taub hau, arrhythmia, co ntawm cov extremities, tsis tshua muaj ntshav siab, mob plab, palpitations, xeev siab, lub plawv mob, kub siab, tsis haum Kev sib txeeb, ntuav, raws plab, txo cov ntshav qabzib, ntau tawm hws, hloov cov zis kuaj.

Cov lus qhia tshwj xeeb

Hauv qhov xwm txheej twg koj yuav tsum tau ua nrog ceev faj txog "Eufillin"? Cov kws ua pov thawj cov lus tim khawv ua tim khawv hais tias cov tshuaj no yuav tsum yog siv raws li tus kws kho mob cov kws kho mob thiab nws yog tus saib xyuas, tshwj xeeb tshaj yog tias tus neeg mob muaj qhov kub taub hau tsis paub txog. Nrog ceev faj, cov tshuaj yuav tsum tau noj rau cov neeg laus.

Nws yuav tsum raug sau tseg tias cov tshuaj "Eufillin" tau nce qib ntawm uric acid nyob rau hauv cov zis. Thaum siv cov tshuaj no, yuav tau saib xyuas tshwj xeeb thaum siv ntau yam khoom noj thiab haus dej qab zib uas muaj caffeine.

Ua ntej parenteral thawj coj ntawm cov tshuaj tov yog pom zoo kom tau rhuab mus lub cev kub.

Tshuaj Kev Sib Thoob

• Nrog tib lub sij hawm siv nrog cov tshuaj no, qhov nyhuv bronchodilating ntawm Salbutamol thiab Terbutaline muaj ntau ntxiv.
• Simultaneous txais tos ntawm lub tshuaj "Eufillin", tus nqi ntawm qhov twg tsis tshaj 40 Lavxias rub, nrog rau cov beta-blockers tau yooj yim ua mob bronchospasm.
• Nyob rau ntawm daim ntawv thov tshuaj no, nws yuav tsum tau ua rau lub hlwb nco ntsoov tias nws cov kev mob tshwm sim muaj kev kho mob zoo li qub los ntawm kev siv tshuaj xws li "Erythromycin" thiab "Cimetidine", nrog rau tshuaj tiv thaiv kab mob npaws thiab cov tshuaj tiv thaiv qhov ncauj.
• Cov theem ntawm cov tshuaj no nyob rau hauv cov ntshav ntws nrog simultaneous siv tshuaj "Carbamazepine", "Rifampicin" thiab "Phenytoin."