Cov tsos mob txuam nrog hemolytic-uremic syndrome thiab nws cov kev kho mob

Yog li ntawd, yog dab tsi koj yuav tsum paub ua ntej ntawm tag nrho vim rau qhov hemolytic-uremic syndrome (abbreviated - HUS). Cov kws kho mob tus cwj pwm tus kab mob no mas nrog peb cov tsos mob: mob raum tsis ua hauj lwm, hemolytic anemia, thrombocytopenia. Nws yuav tsum tau muab sau tseg tias tom kawg feature feem ntau yog manifested feem ntau kom meej meej. Tus kab mob thiaj paub tias yog feem ntau nyob rau hauv cov me nyuam yaus.

tau ua

Lub ntsiab yam tseem ceeb uas yog txuam nrog rau hemolytic-uremic syndrome - ib tug tsis haum cov tshuaj tiv thaiv rau cov tshuaj noj, raws li zoo raws li lub kab mob. Nws yog ib zajlus kom tias tus kab mob pib los tsim tom qab mob ua pa thiab lub plab kab mob los yog nyob rau hauv cov neeg mob uas tau txais tshuaj tua kab mob. Nrog kev xav txog cov pathogenesis ntawm HUS, nyob rau hauv no hwm, qhov loj tshaj tseem ceeb yog txuas mus rau lub xub ntiag ntawm autoimmune tshua. Nyob rau hauv tej rooj plaub, tej zaum lawv yuav txawm muab sawv mus mauj microangiopathy.

symptomatology

Yuav ua li cas tej yam tshwm sim feem ntau yog tshwm sim los ntawm hemolytic uremic syndrome? Nws yuav tsum tau muab sau tseg tias cov hoob kawm ntawm tus kab mob los ntawm cov kws kho mob conventionally muab faib mus rau hauv peb lub sij hawm. Ua ntej, prodromal, yuav nyob ntev li ntawm ib hnub rau ob lub lim piam. Ob, yog li ntawd-hu ua "ntsoog lub sij hawm" - los ntawm ib mus rau peb lub lis piam. Ces los txog rau rov qab lub sij hawm (los yog txoj kev tuag) ntawm tus neeg mob.

Thawj feem ntawm tus kab mob raws li ib tug tag nrho tsa raug kuab lom thiab yog nrog los ntawm cov tsos mob xws li ntuav, mob plab mob, raws plab nrog ib co kua nplaum ntawm cov ntshav. Ib txhia neeg nyob rau hauv no theem cim convulsions, nkees nkees thiab txawm tsis nco qab. Tom qab ib tug prodromal lub sij hawm nyob rau hauv ntau cov neeg mob muaj los ib tug pom rov qab. Nrog haemolytic uraemic syndrome txuam tshwj xeeb raws li haemolytic anemia, thrombocytopenia, thiab lub raum txhab. Cov kws kho mob hais tias tus soj ntsuam daim duab, raws li ib tug txoj cai, txawv los ntawm ib tug polymorphism. Nyob rau hauv ib co neeg mob, cov tsos mob tej zaum yuav tus thawj hemolytic ntsoog, lwm leej lwm tus - tej yam tshwm sim ntawm mob raum tsis ua hauj lwm. Common rau txhua tus neeg mob yog ib tug kos npe rau ntawm hemolytic anemia - nws zoo nkaus li nyob rau hauv lub midst ntawm HUS.

Hemolytic-uremic syndrome nyob rau hauv cov me nyuam nyob rau hauv lub thib ob theem yog yus muaj los ntawm ib tug deathly pallor ntawm daim tawv nqaij. Nyob rau hauv lub xub ntiag ntawm daj ntseg yuav yuav ntes tau hyperbilirubinemia. Direct Coombs 'kev kuaj ntawd yog feem ntau tsis zoo, nws txo qis hemoglobin, tus xov tooj ntawm erythrocytes txo. Tsis tas li ntawd, cov neeg mob feem ntau lub qhov ntswg yog los ntshav.

diagnostics

Cov kws kho mob feem ntau yog kev tshawb nrhiav HUS, raws li nyob rau hauv peb lub ntsiab no: lub xub ntiag ntawm hemolytic anemia, thrombocytopenia purpura thiab uremia. Nyob rau hauv dav dav, lub soj ntsuam daim duab yog reminiscent ntawm Moshkovitsa syndrome (mob raum, ntshav txhaws cov hlab ntsha, thiab hais txog. D.), Nrog qhov txawv tsuas yog tias cov tom kawg yog feem ntau pom nyob rau hauv cov me nyuam hlob, thiab mikrotrombozov tshwm sim tsuas yog nyob rau plawv thiab mob siab.

Hemolytic uremic syndrome: kev kho mob

Hluav autoaggression - uas yog lub ntsiab lub hom phiaj ntawm kev kho mob. Raws li ib tug txoj cai, cov kws kho mob xa tag nrho cov rog tawm los mus tiv thaiv intravascular coagulation. Zoo pab heparin thiab prednisolone. Yog hais tias cov tshuaj tsis pab, nws yog qhia hemodialysis.