Cov tshuaj "Betagestin" los ntawm Kiv tauv hau. "Betahistine": cov lus qhia rau kev siv, nqe, xyuas

Yuav ua li cas puas cov tshuaj "Betahistine" (ntsiav tshuaj)? Cov lus qhia rau kev siv, xyuas, piav qhia thiab thaj chaw ntawm cov tshuaj uas hais no hauv qab no. Nyob rau hauv tas li ntawd, peb yuav qhia rau koj hais txog dab tsi lub cuab tam yog muab rau, yuav ua li cas npaum li cas nws cov nqi, yog hais tias lawv muaj kev phiv thiab contraindications.

Muaj pes tsawg leeg, zoo piav qhia thiab

Tso daim ntawv ntawm cov tshuaj nyob rau hauv ib tug - tshuaj. Txawm li cas los, lawv yog muaj nyob nrog ua nqi ntawm lub active tshuaj:

• Valium dawb ntsiav tshuaj yeej zoo sau tias koob tshuaj active ingredient (betahistine dihydrochloride) - 8 mg.
• Oblong thiab biconvex ntsiav tshuaj nrog sib npaug npoo uas sau tias koob tshuaj active ingredient (betahistine dihydrochloride) - 16 los yog 24 mg.

Raws li koom haum pab khoom xyaw zoo cov ntaub ntawv muaj sodium lauryl sulfate, sodium croscarmellose, microcrystalline cellulose, magnesium stearate thiab citric acid.

Lub pharmacological kev txiav txim ntawm cov tshuaj

Yuav ua li cas yog cov tshuaj "Betahistine?" Cov lus qhia rau kev siv (tus nqi ntawm cov tshuaj nram qab no) qhia tias cov tshuaj yog ib qho analogue ntawm histamine, uas yog tsim synthetically.

Active muaj peev xwm ntsiav tshuaj raus histamine H-3 thiab H-1 receptors (muaj zog thiab tsis muaj zog antagonists) Cns (i.e., receptors ntawm lub vestibular nuclei thiab puab pob ntseg).

Tom qab cov tshuaj yog tam sim ntawd muaj feem xyuam rau cov ntshav khiav, txhawb stimulation ntawm microcirculation thiab permeability ntawm lub inner pob ntseg hlab ntsha. Tsis tas li ntawd, lub active feem ntawm cov medicament yog tau tswj lub siab nyob rau hauv lub endolymph cochlea.

Vim lub fact tias "Betahistine" yog ib qho inhibitor ntawm H 3 receptors nuclei vestibular system, nws muaj ib tug qhia tau ntxim rau cov Cns. Yog li, qhov suav hais tias cov tshuaj stabilizes lub kis tau tus mob (neuronal) neurons nyob rau hauv lub vestibular nucleus.

Nrog rau txoj cai koob tshuaj, nws muaj peev xwm mus sai sai txaus los mus tshem tawm cov cim ntawm vestibular Kiv tauv hau. Lub sij hawm ntawm raug ntawm lub active ingredient ntawm cov tshuaj yog hom twg los ntawm ib tug ob peb feeb mus rau ib hnub.

Tsis tu ncua kom tsawg ntawm cov tshuaj nyob rau hauv ib tug kws kho mob saib xyuas thiaj li cov xwm txheej ntawm kiv taub hau, thiaj li ringing thiab ringing nyob rau hauv lub pob ntseg, thiab restores lub rooj sib hais nyob rau hauv nws deterioration.

Cov tshuaj no muaj tsis muaj kev ua kom loog thiab tsis ua teeb nyob rau hauv lub kom sib haum.

pharmacokinetic zog

Tshuaj "Betagestin" los ntawm Kiv tauv hau yog absorbed sai thiab tag. Nws ncov ntshav ntau yog tiav nyob rau hauv hais txog 65 feeb tom qab noj cov kev yoo mov.

Lub active tshuaj ntawm lub medicament txuam nrog rau cov protein ntau rau tsawg tshaj li 5%.

Muab tau los ntawm kev siv yeeb tshuaj metabolize mus tsaug zog metabolites - demetilbetagistina thiab 2-pyridylacetic acid. Cov yuav luag tiav tshem tawm ntawm cov tshuaj yuav siv sij hawm qhov chaw thaum lub sij hawm lub hnub los ntawm ob lub raum (90%). Rau cov seem 10%, lawv muaj tso tawm los ntawm cov hnyuv.

indications

Tshuaj "Betagestin" los ntawm kiv taub hau muab tus neeg mob ntau heev. Nyob rau hauv tas li ntawd, ib tug yeeb tshuaj siv rau cov kev kho mob ntawm Meniere lub syndrome, raws li zoo raws li mus tshem tawm cov suab nrov nyob rau hauv lub pob ntseg, hnov xeev xeev siab, ib nrab tsis hnov lus thiab tsis hnov sib haum.

Nws yuav tsum tau muab sau tseg tias Meniere lub syndrome manifests raws li hnov thiab vestibular mob uas twb tsis yav tas los cai nyob rau hauv tib neeg. Nws tseem yuav tshwm sim nyob rau hauv daim ntawv ntawm cov mob stroke. Meniere lub syndrome muaj ib tug high yuav nquag rov.

Contraindications

Tam sim no koj paub lub hom phiaj uas tus tshuaj no yog siv "Betagestin". Los ntawm Kiv tauv hau nws yam zoo heev. Txawm li cas los, cov tshuaj no muaj contraindications. Nws yuav tsum tsis txhob muab rau cov neeg uas pheochromocytoma.

Txij li thaum lub active tshuaj yog ib tug hluavtaws analogue ntawm histamine, nws siv tej zaum yuav ua rau kom qhov kev tso tawm ntawm catecholamines, uas nyob rau hauv lem ua rau muaj mob loj tawg.

Nws yuav tsum tau muab sau tseg tias cov ntaus ntawv ntawm "betahistine" Ntsiav tshuaj yog txhob nyob rau hauv cov neeg mob uas npau taws me ntsis rau lub active tivthaiv, los yog mus rau lwm yam cam hauv nyob tus yeees ntawm cov tshuaj.

Cov lus qhia tshuaj

Tshuaj "Betagestin" los ntawm Kiv tauv hau yuav tsum muab nruj me ntsis nyob rau hauv raws li cov lus qhia nkag.

• Ntau npaum rau cov neeg laus cov neeg mob.

"Betahistine" ntsiav tshuaj noj tom ib tug ntau npaum ntawm 8 los sis 16 mg peb zaug ib hnub twg (thaum pib ntawm kev kho mob) ua ke nrog ib tug noj mov los yog tom qab nws. Cov txij nkawm koob tshuaj mas nws txawv tshuaj 24-48 mg ib hnub twg (ntawm tus kws kho mob txiav txim).

Lub sij hawm ntau npaum ntawm cov tshuaj yuav tsum tsis txhob muaj ntau tshaj li 48 mg. Nws yog kho rau tag nrho cov neeg mob. Tej zaum cov kev txhim kho ntawm nws tus mob yuav tsum tau cai tsuas yog tom qab ib tug ob peb lub lis piam.

• Kev kho mob ntawm cov neeg uas muaj lub plawv, raum thiab lub siab tsis ua hauj lwm.

Rau cov neeg mob nrog xws li mob tshuaj "Betahistine" tej zaum yuav tau tsa tsuas yog tom qab ib tug kws kho kev xeem.

• Kev kho mob ntawm cov neeg laus.

Nyob rau hauv cov laus hnub nyoog, cov tshuaj yuav tsum tau muab nrog huab ceev faj. Qhov no yog vim lub fact tias nyob rau hauv pab pawg neeg no ntawm cov neeg mob muaj yog ib tug zoo yuav ua rau muaj kev phiv los ntawm tus kab mob mus rau lub koom haum pab thiab active tshuaj, uas yog ib feem ntawm lub ntsiav tshuaj.

• Kev kho mob ntawm cov me nyuam thiab cov tub ntxhais hluas.

Tshuaj "Betagestin" los ntawm Kiv tauv hau yog tshuaj rau cov me nyuam thiab cov tub ntxhais hluas (tsawg tshaj li 18 xyoo). Qhov no yog vim tsis muaj kev miv nyuas siv zug thiab kev nyab xeeb cov ntaub ntawv tshuaj.

tus neeg mob ntawm overdose

Yog hais tias overdose "Betahistine" ib co neeg mob tej zaum yuav muaj cov tsos mob xws li xeev siab, mob taub hau mob, mob nyob rau hauv lub plab thiab nkees nkees (thaum noj ib koob tshuaj mus rau 640 mg).

Tsis tas li ntawd, cov neeg mob tej zaum yuav tsis txaus siab ntawm tu-sauv, ntuav, dyspepsia, thiab ataxia.

Yog xav paub ntxiv loj teeb meem muaj xws li mob plawv thiab pulmonary teeb meem (cai nrog txhob txwm overdose).

Kev Kho Mob - ntxuav lub plab tsis pub dhau 60 feeb tom qab thawj coj.

phiv

Tsis yog txhua txhua tus neeg mob noj cov tshuaj "Betagestin", tej zaum yuav muaj kev tsis xis nyob.

Cov kws kho mob tau qhia hais tias lub manifestation ntawm cov nyom tshua thaum noj tej yam tshuaj rau tus neeg mob tej zaum yuav txhais tau li cas adapting rau tshiab tshuaj. Nyob rau hauv no kev twb kev txuas, koj yuav tsum mus tham nrog koj tus kws kho mob ua ntej discontinuing cov tshuaj.

Common phiv los ntawm kev noj "betahistine" cai ib nyob rau hauv kaum tus neeg mob. Lub daim ntawv teev cov feem ntau phiv los muaj xws li cov tsos mob xws li:

• mob plab (feem ntau yog tshwm sim thaum noj tshuaj ua ntej ib tug noj mov);
• general malaise;
• tsis xis nyob los yog tsam plab;
• mob taub hau (koj muaj peev xwm coj painkillers, tab sis tsuas yog tom qab ua ntej kev sib tham nrog ib tug kws);
• Cov kev tsis haum ntawm daim tawv nqaij nyob rau hauv daim ntawv ntawm cov khaus thiab ua pob liab vog (yuav tsum tau antihistamine los yog roj teeb meem chaw moisturizer).

Yog hais tias saum toj no raws li kev cai tsis pab tshem tawm cov kev phiv, tus neeg mob xav tau kev pab mus ntsib ib tug kws kho mob.

Tus nqi ntawm cov tshuaj

Nqe "Betahistine" Ntsiav tshuaj tej zaum yuav txawv thiab nyob ntawm seb tus nqi ntawm cov tshuaj nyob rau hauv lub pob. Cov tshuaj ntawm ib koob tshuaj ntawm 24 mg yuav tau muas rau 60-65 rubles. Muaj ntau cov neeg mob ntseeg tau hais tias nws yog ib tug heev tsawg tus nqi tshuaj.

Xyuas ntawm cov tshuaj

Xyuas ntawm "Betahistine" formulation yog mixed. Ib txhia neeg uas mob kab mob plawv coj lub ntsiav tshuaj tsis tu ncua. Txawm li cas los, lawv yeej tsis tshem tawm cov mob taub hau thiab kiv taub hau.

Thiab qhov tsis zoo thiab zoo xyuas txog qhov no medicament qhia hais tias nws yuav tsum tau ib tug tshwj xeeb daim ntawv thov.

Yog li, thaum ib tug abuses cov tshuaj "Betahistine" yuav sai sai rov qab kho cov kev kho mob ntawm tus neeg mob, thaum lub lwm yam, nyob rau hauv tsis tooj, tsis muaj cov yam nyhuv, tiam sis tsuas yog txo cov tsos ntawm cov tsos mob.