Calprotectin nyob rau hauv quav - yog dab tsi? Vim li cas nce

Calprotectin nyob rau hauv quav - yog dab tsi? Qhov no yog ib tug protein uas yog tso tawm los ntawm cov qe ntshav dawb (macrophages thiab qe) thaum lawv tshuab txais los yog txoj kev tuag. Nws ua hauj lwm pab raws li ib tug kev marker ntawm inflammatory dab nyob rau hauv cov hnyuv. Ntau nqi ntawm txoj kev tshawb no yog ncaj qha proportional rau tus xov tooj ntawm cov ntshav dawb uas yog nyob rau hauv cov hnyuv.

Calprotectin nyob rau hauv quav - yog dab tsi?

Qhov no tshuaj yog tau muab tso tawm tsuas nyob rau hauv tshuab txais ntshav dawb (qe) los yog tuag lawm. Nyob rau hauv qhov tseeb, nws Neutrophil protein los yog ib tug protein uas yog txuam nrog poov hlau. Calprotectin nyob rau hauv cov quav - nws, thiab nyob rau hauv dab tsi tshwm sim nws zoo nkaus li nyob rau hauv lub gut?

Nyob rau hauv inflammatory plob tsis so tswj kab mob naj npawb ntawm cov leukocytes therein tsub kom. Leukocytes, namely qe, uas tawm tsam nrog tus kab mob no, uas tau nyob rau hauv tus tuag. Thaum lawv tuag tshwm sim protein tawm - calprotectin, thiab qhov no ua rau nws muaj zog nyob rau hauv concentration faeces.

Kev Txiav Txim ntawm ntau cov ntsiab lus ntawm calprotectin nyob rau hauv cov quav - yog yooj yim thiab tsis yog-tus qauv ntawm cov diagnosing inflammatory plob tsis so tswj kab mob (IBD). Qhov no mob pub rau cov kws kho mob yuav qha IBD los ntawm chim siab plob tsis so tswj syndrome uas tsis muaj peculiar o ntawm lub qog ua kua membrane ntawm tus mob huam (GIT).

Thaum nws tau tsa?

Txoj kev tshawb no yog muab yog hais tias tus neeg mob muaj cov nram qab kev tsis txaus siab:

• Lus quav nrog hnoos qeev.
• Xoob quav nrog cov ntshav.
• Mob plab thiab no nce nyob rau hauv lub cev kub.
• Tawm fws.
• Sudden poob phaus.
• General tsis muaj zog thiab kev qaug zog nrog me ntsis lub cev dag zog.
• Nyob rau hauv cov ntaub ntawv ntawm kev ua txhaum cai plab hnyuv kom.
• Xeev siab thiab ntuav.
• Yog hais tias cem quav.
• Nyob rau hauv tus neeg mob qhov twg lub xub ntiag ntawm tus neeg mob pathologies ntawm perinatal cheeb tsam, xws li ua paug los yog fistulas.
• Nyob rau hauv cov me nyuam uas muaj kev ncua sij hawm.

Calprotectin nyob rau hauv cov quav: qub

Qhov tseem ceeb ntawm no parameter nyob rau hauv cov quav feem ntau roos los ntawm 0 mus rau 10 mg / ml. Yog hais tias cov quav calprotectin theem yog nyob rau hauv no ntau yam, nws txhais tau tias tus neeg mob tsis muaj IBD. plab hnyuv mucosa yog tsis kub lug. Thiab yog hais tias tus neeg mob tseem tsis txaus siab ntawm plab hnyuv muaj teeb meem thiab raws plab, tej zaum nws yuav txhais tau hais tias nws yog tam sim no chim siab plob tsis so tswj syndrome. Ntxiv cov kev tshawb fawb yuav tsum tau mus hais tus mob.

Uas txhais tau hais ntau zog calprotectin theem

Yog hais tias calprotectin nyob rau hauv cov quav ntau zog, cov ua yuav kev cob cog rua tsis tau tsuas yog nrog IBD, tab sis kuj tiv thaiv kab mob los yog kab mob cov kab mob ntawm tus mob huam, xws li tus kab mob Salmonella, Campylobacter. Xws li ib tug tshuaj tiv thaiv yuav muab rau muaj kab mob zawv plab, norovirus los yog adenoviral kab mob. Tsis tas li ntawd, tej zaum nws yuav calprotectin nyob rau hauv cov quav nce nyob rau hauv kev tsis haum cov tshuaj tiv thaiv rau nyuj cov kua mis los yog celiac kab mob (intolerance rau gluten muaj nyob rau hauv cereal haiv neeg) raws li tau zoo raws li lub xub ntiag ntawm txhab, diverticula hnyuv los yog cystic fibrosis (ib tug pub kab mob txuam nrog txhab ntawm lub endocrine qog lwm secretion).

Nyob rau hauv txhua rooj plaub nqa tawm txoj kev tshawb no?

Xav txog thaum lub muab txoj kev tshawb no tso cai rau kom qhia calprotectin nyob rau hauv cov quav. Yuav ua li cas nws yog, peb twb pom tawm.

Ib tug zoo xws li cov kev tshawb nyob rau hauv cov neeg mob muab:

1. Raws li ib tug tiv thaiv kev xeem nyob rau hauv prophylactic xeem.
2. Rau tej xav tias IBD.
3. Thaum hnyuv los ntshav.
4. Yog hais tias tus neeg mob tsis txaus siab ntawm plab mob thiab cov kev soj ntsuam daim duab.
5. Rau differential mob ntawm chim siab plob tsis so tswj syndrome.

Yuav ua li cas?

Yog hais tias nws muab tawm hais tias calprotectin nyob rau hauv cov quav ntau zog, yog vim li cas xws li ib tug tshuaj tiv thaiv yuav tsum tau teem los ntawm tus kws kho mob. Self-indulge nyob rau hauv txhua rooj plaub tsis tsim nyog nws, vim hais tias nws yuav ua tau ib tug heev muaj mob loj. Tus kws kho mob yuav raug kuaj, thiab tej zaum kuj ntxiv cov kev tshawb fawb tej zaum yuav tsum tau:

• Coprogram.
• Cov tshuaj tiv thaiv Gregersen, los yog quav Occult ntshav. Tej tsom xam yuav tsum tau tshwj xeeb kev cob qhia. Rau peb hnub, tus neeg mob yuav tsum tsis txhob noj cov nqaij thiab cov ntses tais diav, raws li zoo raws li cov khoom uas muaj nyob rau hauv nws muaj pes tsawg leeg iron (daim siab, qe, dub Currant, chocolate).
• C-reactive protein yog ib co rhiab txoj kev uas tso cai rau los mus txiav txim lub quantitative tshwm sim.
• Rheumatoid tau.
• Cea (carcinoembryonic antigen).
• ANA (antibodies mus nuclear antigens).
• Tag nrho cov ntshav uas yuav tsum tau suav leukocyte mis.

kev kho mob

Yog li ntawd, tus kws kho mob muab ib tug muaj tseeb mob, nyob rau hauv uas muaj cov cim qhia ntawm o ntawm lub plab hnyuv mucosa, thiab yog li muaj zog calprotectin nyob rau hauv cov quav. Kev kho mob yuav nyob ntawm seb yog vim li cas uas tshwm sim los no o.

Yog hais tias lub culprit ib hom kab mob, xws li tus kab mob salmonella, uas yuav tsum tau kev kho mob, uas muaj peev xwm ua kom puas lub pathogen (Salmonella). Tsis tas li ntawd yuav tsum tau sorbents, xws li "Liferan", "dawb thee", "Enterodez", "Smecta", thiab lwm yam Nyob rau hauv tas li ntawd, tus tsim nyog npaj rau lub restoration ntawm dej-ntsev tshuav nyiaj li cas :. "Oral", "Regidron", thiab lwm yam Thaum lub teeb. daim ntawv ntawm cov salmonellosis feem ntau tshuaj tua kab mob yuav tsis tsa vim hais tias no neeg uas sawv cev tiv thaiv kab mob rau lawv.

Thaum lub kab xwm ntawm tus kab mob (adenovirus los yog kab mob rotavirus li al.) Xav tau antivirals. Qhov no yuav ua tau "Arbidol" "Gordoks" "Virazole" thiab al. Applied immunostimulating thiab immunomodulating tshuaj "TSikloferon" "Anaferon", "interferon".

Feem ntau rau tej cov kev kho mob ntawm plab hnyuv kab mob muab tshuaj tua kab mob. Piv txwv li, tus kws kho "Ftalazol" thiab cov me nyuam yog siv raws li ntau li ntau tau ib tug muaj kev ruaj ntseg antibacterial neeg sawv cev nrog ib tug broad spectrum ntawm kev txiav txim "cefixime".

Ib tug zoo zoo yog muab enzyme npaj "enzistal", "Festal".

Tab sis kev kho mob yuav tsum appoint ib tug kws kho mob nyob ntawm tus neeg tus yam ntxwv ntawm tus neeg mob thiab nws tus mob.