Benzylpenicillin sodium ntsev: cov lus qhia rau kev siv. daim ntawv thov kev cai

Nyob rau hauv no tsab xov xwm uas peb yuav tham txog tej kev npaj raws li "Benzylpenicillin sodium ntsev". Cov lus qhia rau kev siv, indications, ntau npaum thiab cov tswv yim rau siv yuav tsum tau them nyob rau hauv tsab xov xwm. Nyob rau hauv tas li ntawd, peb xav txog lub pharmacological thaj chaw ntawm cov tshuaj, tau tshwm sim thiab tshuaj cov kev sib tshuam nrog lwm yam tshuaj.

tag nrho

Cov tshuaj no yog ib qho antimicrobial neeg sawv cev thiab ib tug tshuaj tua kab mob teej tug mus rau lub penicillin pab pawg neeg. Benzylpenicillin sodium ntsev nws tus kheej, cov lus qhia rau kev siv ntawm cov uas yuav tsum tau hais hauv qab no yog ua los ntawm ntau yam fungi.

Tshuaj nyob rau hauv pab pawg neeg no yog siv rau cov intramuscular cov thawj coj, los ntawm cov ntau yam ntaub so ntswg thiab kabmob nyob rau hauv uas cov ntshav muab ib tug me me npaum li cas ntawm penicillin. Mus rau yeeb tshuaj pib muaj teebmeem rau lub paj hlwb thiab tus txha caj qaum thiab meninges, subarachnoid muab.

Benzylpenicillin sodium ntsev, cov lus qhia rau kev siv: pharmacologically txiav txim

Cov tshuaj no yuav siv tau tiv thaiv kab-zoo cov kab mob, uas muaj xws li:

• staphylococci;
• streptococci;
• pneumococci;
• diphtheria ;
• coli anthrax;
• aerobic (tseem muaj sia nyob rau hauv lub qhaj ntawv ntawm cov pa) sporulating rods.

Tsis tas li ntawd, cov tshuaj yog active tiv thaiv kab mob cocci (meningococcus, gonococcus), spirochetes, actinomycetes thiab lwm yam kab mob. Penicillin sodium ntsev yog tsis zoo tiv thaiv cov kab mob, rickettsiae, fungi, protozoa.

Tshuaj resistant kab mob los ntawm staphylococci, uas muaj peev xwm sawv ntawm qhov uas ua lub enzyme penicillinase, disintegrating benzylpenicillin. Lub medicament exhibits tsawg yam kev ua si nyob rau hauv cov kev kho mob ntawm Pseudomonas aeruginosa, plab hnyuv kab mob thiab lwm yam kab mob, uas yog tau faib ntau nqi ntawm penicillinase.

tshuaj

Nyob rau hauv intramuscular tshuaj sai nkag mus rau hauv cov hlab ntsha, los ntawm qhov uas yog xa mus rau lub lub cev thiab cov nqaij mos. Nrog kev xav txog cov hlwb txha nqaj qaum kua, nws penetrates mus rau ib tug me me npaum li cas ntawm penicillin. Qhov siab tshaj plaws nyob rau hauv concentration ntshav tom qab nws koom haum saib xyuas intramuscularly cai tom qab 30-50 min. Yog hais tias cov tshuaj yog muab subcutaneously, tus nqi ntawm haum yog txo kom tsawg thiab lub siab tshaj plaws pes tsawg tus ntawm tshuaj nyob rau hauv cov ntshav yuav tsum tau cai nyob rau hauv ib teev.

Peb teev tom qab txhaj tshuaj (subcutaneous los yog intramuscular) ntawm benzylpenicillin tsuas ib co kua nplaum nyob twj ywm nyob rau hauv cov ntshav. Yog li ntawd, kom muaj ib tug siab concentration ntawm cov tshuaj nyob rau hauv lub cev rau ib ntev lub sij hawm, nws yog tsim nyog los hno los ntawm txhua plaub teev.

Thaum muab intravenously, nws concentration ntawm cov tshuaj sai ntog. Thiab thaum noj ntawm ncauj benzylpenicillin yog muab los ntawm penicillinase (enzyme) thiab pais plab kua txiv.

Tas cov tshuaj tas nyob hauv cov zis.

zaj lus tim khawv

Lawv yuav tsum tau ua tib zoo kawm ua ntej lub sij hawm teem ntawm cov tshuaj raws li penicillin sodium ntsev, cov lus qhia rau kev siv, tshuaj thiab indications rau siv. Peb pib nrog cov tom kawg. Yog li, cov tshuaj yog tshuaj:

• nyob rau hauv cov kab mob ntawm lub ntsws thiab ua pa ib ntsuj av tau;
• mob loj heev lub taub dej khawb kab mob;
• kab mob endocarditis;
• sepsis;
• kab mob thiab kab mob qhov txhab ntawm cov nqaij mos mos, daim tawv nqaij thiab qog ua kua week;
• kub nyhiab;
• o ntawm cov leeg nrob qaum thiab lub hlwb, mazgovyh tawv;
• purulent pleurisy;
• peritonitis;
• cystitis;
• Pius thiab Septicemia;
• osteomyelitis;
• diphtheria;
• kub taub hau;
• gonorrhea;
• erysipelas;
• Cov kab mob nyob rau hauv cov me nyuam mos;
• anthrax;
• syphilis;
• actinomycosis;
• ntau yam gynecological inflammations;
• inflammatory kab mob ntawm lub caj pas, pob ntseg thiab qhov ntswg.

Cov ntsiab lus uas siv thiab ntau npaum

Nyob ntawm seb lub hom mob txoj kev kho siv benzylpenicillin sodium ntsev ntawm cov tshuaj yuav tsum muab. Cov lus qhia rau kev siv, lawv cov thawj coj thiab tau ntau npaum yuav muab suav hais tias los ntawm peb nyob rau hauv seem no.

Hoob no ntawm txoj kev siv tshuaj yuav kav, nyob ntawm seb tus kab mob, los ntawm 4 lub lis piam mus rau 2 lub hlis los yog ntau txawm tias. Cov tshuaj yuav tsum muab nyob rau hauv lub nram qab no:

• Intramuscularly rau hauv lub Upper txheej quadrant ntawm lub gluteal. Cov kev npaj yog diluted ua ntej thawj coj nyob rau hauv dej distilled, novocaine los yog sodium tshuaj dawb tov.
• Tso dej - .. Tsuas yog nyob rau xws mob loj heev cov kab mob, xws li meningitis, kab mob endocarditis, Septicemia, etc. Lub tshuaj no yog muab txhua txhua 4 teev los yog nruam nrog - 30 ncos ib feeb rau 6-12 teev.
• Nws tej zaum kuj yuav muab endolyumbalno benzylpenicillin sodium ntsev. Cov lus qhia rau kev siv (thov txoj kev) muab ib tug qauv rau kev o ntawm lub paj hlwb thiab tus txha caj qaum, nrog rau cov meninges. Cov tshuaj no yog txhaj heev maj mam - 1-2 feeb.
• Muaj mob qhov twg benzylpenicillin siv rau txhaj cov inflammatory foci. Piv txwv li, thaum actinomycosis, daim tawv nqaij leishmaniasis, mob pyoderma thiab lwm yam kab mob daim tawv nqaij kab mob.
• Nrog inhalations - rau cov kev kho mob thiab kev tiv thaiv ntawm cov kab mob ntawm lub ntsws thiab cov hlab cua. Rau lub hom phiaj no, tov nrog benzylpenicillin sodium tshuaj dawb tov los yog distilled dej. Inhalations tsis muaj ntau tshaj li 2 lub sij hawm ib hnub. Lasting ib kev kho mob - los ntawm 10 mus rau 30 feeb.
• Nws kuj txhaj mus rau hauv lub pleural los yog peritoneal kab noj hniav nyob rau hauv purulent peritonitis los yog pleurisy.
• Nyob rau hauv daim ntawv ntawm cov xyuas kom tseeb tias, tshuaj pleev, noo cov ntaub qhwv, muab tshuaj pleev thiab cov hmoov - rau kub yus, qhov txhab ntawm qhov muag ntaub so ntswg, thiab osteomyelitis al.
• Tsis tas li ntawd, cov tshuaj tov siv rau cov kev kho mob ntawm Upper pa ib cov kab mob thiab nyob rau hauv Ophthalmology.

Penicillin yuav siv tau nyob rau hauv txoj kev kho ua ke nrog rau lwm cov tshuaj tua kab mob thiab sulfanilamide npaj. Wherein cov txhais tau tias yuav txhawb ntxiv rau kho nyhuv ntawm cov tshuaj siv.

phiv

Nws kuj muaj ib tug tsis zoo feem ntawm benzylpenicillin sodium. Cov lus qhia rau kev siv sau ntawv hais tias lawv muaj qhia los ntawm tso dej thawj coj ntawm cov tshuaj feem ntau.

Yeej, tus phiv nrog kev tsis haum tshuaj mus rau yeeb tshuaj. Ntawm cov kev phiv cov tsos mob tias:

• Candidiasis;
• ua xua;
• kub taub hau;
• mob taub hau;
• ua daus no;
• mob tej pob txha;
• Angioedema;
• eosinophilia;
• ntau hom dermatitis;
• kub taub hau;
• lymphadenopathy;
• anaphylactic poob siab - nyob rau hauv tsis tshua muaj heev neeg mob.

Contraindications

Tsis yog txhua txhua tus neeg mob yuav ua txoj kev kho nrog ib tug medicament ntawm benzylpenicillin sodium ntsev. Cov lus qhia rau kev siv thiab cov kev cai ntawm koom haum saib xyuas muab ib tug xov tooj ntawm contraindications. Cov lawv:

• kev tsis haum cov kab mob xws li urticaria, hay fever, bronchial hawb pob, thiab lwm yam.;
• npau taws me ntsis rau penicillin derivatives;
• txawv txawv cov lus teb rau cov tshuaj;
• kab mob yav kuj mus rau ib tug tsev koob tshuaj benzylpenicillin.

Cov kev taw qhia ntawm cov tshuaj endolyumbarnym muaj peev xwm txwv tsis pub nyob rau hauv qaug dab peg.

Cev xeeb tub thiab lactation

Taw thaum lub sij hawm cev xeeb tub yog tias cov kev pab rau cov kev kho mob ntawm cov poj niam yog ntau tshaj lub peev xwm uas yuav muaj rau nws tus menyuam hauv plab. Txwv tsis pub, cov tshuaj yog tsis muab. uas muaj feem yuav piv thiab efficiency yog txiav txim los ntawm lub mus kawm tus kws kho mob.

Yog hais tias tsim nyog, lub koom haum saib xyuas ntawm cov tshuaj thaum lub sij hawm lactation yuav tsum tsis txhob pub niam mis.

zog

Drug tshuaj benzylpenicillin sodium ntsev muaj hauv daim ntawv ntawm dawb zoo crystalline hmoov nrog ib tug ntsim saj uas yog nkag soluble nyob rau hauv cov kua.

Cov tshuaj no yog yooj yim muab los ntawm acids, alkalis, oxidizing agents, enzyme penicillinase, raws li zoo raws li cov cua kub. Npaj cov tshuaj tshuaj yuav tsum tam sim ntawd ua ntej thawj coj.

precautionary ntsuas

Lub tshuaj no yog muab xwb nyob rau hauv lub tsev kho mob los ntawm ib tug kws kho mob tshuaj thiab nyob rau hauv nws saib xyuas. Nrog rau cov zaj uas kho yuav tsum tau nco ntsoov tias tsis txaus koob tshuaj benzylpenicillin los yog thaum ntxov txiav ntawm kev kho mob yuav ua rau cov tsim ntawm resistant kab mob los ntawm microorganisms. Nyob rau hauv cov kev tshwm sim ntawm kuj mus rau yeeb tshuaj kho mob yog txuas ntxiv lwm yam tshuaj tua kab mob.

Lub nyiam kev tsis haum tshuaj muab ua ke nrog antihistaminic tshuaj benzylpenicillin sodium. Cov lus qhia rau kev siv (kev txiav txim ntawm cov tshuaj nyob rau hauv nws cov tshuaj particular nthuav dav) qhia hais tias thaum ib tug neeg mob tsis haum ces txoj kev kho sai li sai tau tso tseg.

Nyob rau hauv tej pab pawg ntawm cov neeg mob (neeg laus, cov me nyuam mos, tsis muaj zog txaus los ntawm tus kab mob) yuav muaj ua hauj benzylpenicillin, uas ua rau txoj kev loj hlob ntawm superinfection.

Nrog heev siv, cov tshuaj tua kab mob yuav suppressed los yog tej kev puas tsuaj los ntawm plab hnyuv microflora, ua rau txo zus tau tej cov vitamins ntawm pab pawg neeg B. Yog li ntawd prophylactically rau cov neeg mob feem ntau muab vitamins B1, B12, thiab lwm tus neeg.

Yog hais tias, tom qab qhov pib ntawm txoj kev kho rau 3 hnub twb tsis pom tej nyhuv, nws yog tsim nyog los mus rau lub neej coj kev kho mob los yog muab ib tug tshiab tshuaj tua kab mob.

ceev faj

Ceev faj muab cov neeg uas muaj lub plawv tsis ua hauj lwm thiab impaired raum muaj nuj nqi benzylpenicillin sodium ntsev. Cov lus qhia rau kev siv kuj xav kom tshwj xeeb xim yuav muab rau cov neeg cov neeg mob uas tau pom meem kev txhawj xeeb rau cephalosporins.

Vim hais tias ntawm tau ntawm fungal superinfection yog pom zoo kom muab cov tshuaj anti-fungal cov kab mob.

Sis nrog lwm yam tshuaj

Nyob rau hauv lub sij hawm ntawm cov neeg tshuaj tua kab mob, uas muaj bacteriostatic, bactericidal kev txiav txim ntawm penicillin txo.

Kev npaj "Probenecid" muaj ib tug mus txo tubular secretion ntawm tshuaj tua kab mob uas tau nyob rau hauv ib qho kev nce rau hauv cov ntshav theem ntawm lub yav tas thiab, raws li ib tug tsim nyog tau, ua rau kom lub sij hawm tshem tawm nws los ntawm lub cev.