"Z-factor": kev txheeb xyuas, cov lus qhia siv, kev phiv

Cov tshuaj "Zi-factor" cov lus qhia rau kev siv txhais tau tias yog cov tshuaj tua kab mob bacteriostatic, uas yog mus rau cov pab pawg ntawm cov tshuaj tsawg dua. Cov tshuaj muaj lub dav spectrum of antimicrobial cov teebmeem. Lub tswv yim ntawm kev ua si yog txuam nrog cov hluav taws xob protein synthesis nyob rau hauv microbial hlwb, li no qeeb txoj kev loj hlob thiab sib npaug ntawm cov kab mob. Cov tshuaj tua kab mob "Zi-factor", kev kuaj xyuas cov neeg mob thiab cov kws kho mob tshwj xeeb uas feem ntau muaj txiaj ntsim, zoo tiv thaiv kab mob thiab lwm yam kab mob gram-negative thiab gram-positive, thiab lwm cov kab mob hauv tsev neeg. Lub caij no, pathogens tuaj yeem yuav tiv taus cov tshuaj los yog tau txais qhov kev ruaj ntseg no thaum siv cov tshuaj.

Pharmacokinetic zog

Cov khoom xyaw ntawm cov tshuaj "Zi-factor" cov lus qhia rau kev siv hu rau azithromycin. Nws yog lub cev zoo kawg nkaus, hauv lub cev yog muab faib sai sai. Tom qab tau txais ib qho ntawm 500 mg ntawm lub tshuaj, bioavailability yog 37 feem pua, tom qab ob peb rau peb teev, cov ntshav tau ua qhov siab tshaj plaws, 0.4 milligrams per liter. Cov tshuaj "Zi-factor" penetrates los ntawm lub week ntawm lub cell thiab yog thauj los ntawm phagocytes mus rau qhov chaw ntawm tus kab mob, qhov twg nyob rau hauv muaj lub pathogen tso tawm. Cov tshuaj yooj yim kis tau cov teeb meem histohematological. Hauv cov ntaub so ntswg thiab hlwb, qhov concentration yog kaum rau tsib caug zaus siab tshaj qhov uas tau pom hauv plasma, tib lub sij hawm hauv qhov kab mob ntawm tus kab mob no yog nruab nrab ntawm 24-34 feem pua siab tshaj hauv cov ntaub so ntswg noj qab nyob zoo. Kev mus rau hauv lub siab, cov tshuaj yog demethylated, thaum kev poob haujlwm. Tom qab noj cov tshuaj muaj nitrate nyob rau hauv cov tshuaj kho kom nyob rau hauv lub cev rau 5 rau 7 hnub, feem ntau yog tsis hloov hauv plab hnyuv (50 feem pua) thiab ob lub raum (6 feem pua).

Cov kev qhia rau kev siv

Cov tshuaj yaj yeeb yog siv rau cov kab mob inflammatory kab mob uas tshwm sim los ntawm cov kab mob ua rau cov tshuaj. Yog li, thov cov tshuaj "Zi-factor" rau qhov kab mob hu ua sinusitis, sinusitis, tonsillitis, otitis media, pharyngitis thiab lwm yam pathologies ntawm ENT plab hnyuv siab raum thiab txoj hlab ntsws. Muab cov tshuaj thiab rau cov kab mob ntawm txoj hlab ntsws qis: bronchitis, mob ntsws, xws li ua rau atypical pathogens. Siv cov tshuaj "Zi-factor" rau kev siv cov lus pom zoo rau cov kab mob ntawm cov nqaij mos, tawv: dermatoses, erysipelas, impetigo; Cov kab mob ntawm tus kab mob genitourinary no: kab mob hauv siab, mob caj pas.

Daim ntawv ntawm qhov teeb meem

Cov tshuaj yog tsim nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj thiab tsiav tshuaj. Ntsiav tshuaj "Zi-factor" biconvex, oblong, them nrog ib lub teeb liab lub tsho loj. Muab ntim rau hauv peb lub thawv ntawv. Capsules ntawm cov xim dawb, tawv, gelatin; Cov ntsiab lus yog sib tov ntawm cov hmoov thiab cov hmoov zeb. Muab ntim rau hauv 6 los sis 10 daim ntawm cov hlwv ntawm cov hlwv.

Muaj pes tsawg leeg

Hauv ib lub ntsiav tshuaj, cov khoom ua muaj mob - azithromycin (nyob rau hauv daim dihydrate) - nyob hauv tus nqi ntawm 500 milligram, thiab hauv ib capsule - 250 milligrams. Raws li txhawb cheebtsam hauv nyob tus yeees ntawm cov ntsiav tshuaj siv povidone, magnesium stearate, dihydrate calcium phosphate, sodium lauryl sulfate, crospovidone, talc, titanium dioxide, liab acid zas, hydroxypropylmethylcellulose, polysorbate. Cov tshuaj phais thib ob hauv cov hlab ntoos yog cov pob kws, cov tshuaj sodium lauryl sulfate, methyl parahydroxybenzoate, lactic sugar, acetic acid, lactopress, aerosil, magnesium stearate, povidone, titanium dioxide, gelatin thiab propyl parahydroxybenzoate.

Daim ntawv thov nta, noj tshuaj

Cov tshuaj yuav tsum tau noj tshuaj txhua hnub, ib teev ua ntej noj mov lossis ob teev tom qab. Thaum cov kab mob ua pa nyhuv, ENT plab hnyuv siab raum, tawv nqaij thiab daim tawv nqaij tau sau ib hnub ntawm 500 mg, cov kev kho yuav kav ntev li peb hnub. Lub hom phiaj ntawm kev kho mob rau lub cev erythema yog raws li nram no: thawj hnub, noj 1000 mg, ntawm ob txog hnub mus rau hnub tsib - 500 mg txhua hnub. Nyob rau hauv ib qho kev tsis sib tov los yog mob caj pas (urethritis) yuav tsum tau noj ib zaug 1000 mg ntawm cov tshuaj. Cov neeg mob uas muaj mob tsis tshua muaj mob plawv tsis tas yuav kho cov tshuaj no.

Cov txheej txheem phiv. Xyuas

Txog qhov tshwm sim ntawm cov kev tsis zoo tshwm sim tom qab noj tshuaj Zi-Factor, cov kev kuaj xyuas yog txawv. Heev feem ntau, cov neeg mob tsis txaus siab ntawm kev zawv plab, xeev siab, ntuav, mob plab, kem plab, nkees nkees. Qee cov neeg mob qhia txog cov kev mob tshwm sim xws li kiv taub hau, kev siab ntsws, mob taub hau. Muaj qee zaus, muaj kev kub ntxhov, kev hnov qab, suab nrov hauv pob ntseg, teeb meem kev hnov lus, kev tsis pom kev hnov tsw thiab saj. Cov lus qhia rau kev siv ntawm cov tau tshwm sim tsis zoo teev thiab xws li paresthesia, asthenia, anorexia, pseudomembranous mob plab, hepatic necrosis, arrhythmia, anemia, nephritis, neutropenia, vaginitis, arthralgia, photosensitivity, angioedema, kab mob siab, lom epidermal necrolysis, erythema multiforme . Tej tus neeg mob yeej ua tim khawv rau kev rov tuaj yeem ua rau aggressiveness thiab kev ntxhov siab tom qab siv tshuaj "Zi-factor." Kev txheeb xyuas, ntawm lwm yam, muaj cov ntaub ntawv qhia tias cov tshuaj muaj peev xwm tswj tau qhov ua kom nrov ntawm tus nplaig, cem quav, tawv nqaij pob khaus thiab khaus.

Contraindications

Nws yog txwv tsis pub siv tshuaj rau cov neeg uas muaj siab mob heev rau cov macrolides, uas muaj kev puas tsuaj ntawm lub raum / lub siab ua haujlwm. Zi-zauv yuav tsis muab rau cov menyuam yaus hnub nyoog qis dua kaum ob. Tsis tas li ntawd, koj yuav tsum tsis txhob siv cov tshuaj rau cov poj niam thaum lub caij ua menyuam lactation, nrog rau dihydroergotamine thiab ergotamine, cov neeg mob uas tsis muaj lactase deficiency, genetic intolerance rau galactose, glucosogalactose malabsorption. Nrog ceev faj, muab cov tshuaj noj rau cov neeg uas muaj mob loj heev ntawm lub raum / siab, arrhythmia los yog qhov tseem ceeb rau nws. Thaum cev xeeb tub, cov tshuaj siv tsuas yog siv cov txiaj ntsim kev cia siab rau leej niam yog siab tshaj qhov yuav raug rau kev loj hlob ntawm tus me nyuam hauv plab.

Overdose

Kev mob plab, xeev siab, ntuav yog tsim tau yog tias koj noj ntau dhau ntawm qhov tshuaj "Zi-factor." Txhua tus neeg ua pov thawj pom tau hais tias qhov tshwm sim ntawm tus yam ntxwv xws li tsis hnov lus zoo li ib ntus. Yog tias muaj qee zaum dhau los, kev kho cov tsos mob yuav tsum tau kho.

Kev sib tham nrog lwm cov tshuaj

Antacids txo cov concentration ntawm azithromycin los ntawm 30% ntawm cov ntshav, yog li cov tshuaj Zi-tshuaj yuav tsum tau noj tsawg kawg ib teev ua ntej lossis ob teev tom qab siv cov tshuaj no thiab khoom noj. Qhov concentration hauv plasma didanosine, methylprednisolone, carbamazepine, rifabutin nyob rau hauv kev sib koom tes ntawm azithromycin tsis cuam tshuam dab tsi. Txawm li cas los, nws cov nyhuv rau cov concentration ntawm cimetidine, indinavir, triazolam, fluconazole, midazolam, efavirenz, trimethoprim tsis tau txiav txim tawm. Yog tias koj xav siv cov tshuaj "Zi-factor" tib lub sij hawm raws li cyclosporine lossis digoxin, koj yuav tsum soj ntsuam cov ntshav cov ntshav qis kawg, thiab thaum nrog cov tshuaj warfarin kom pom zoo kom zoo saib xyuas cov tshuaj prothrombin. Simultaneous kev txais tos ntawm azithromycin thiab terfenadine tuaj yeem ua rau arrhythmia, zoo li mus rau lub caij nyoog QT.

Cov lus qhia tshwj xeeb

Yog tias tus neeg mob tsis nco qab haus cov tshuaj, nws yuav tsum tau noj cov tshuaj uas tsis tuaj yeem sai li sai tau, thiab cov tom qab ntawd - nrog lub sijhawm luv (24 xuab moos). Thaum kho tus mob azithromycin, nrog rau cov tshuaj tua kab mob, muaj kev pheej hmoo ntawm kev sib koom tes, xws li fungal. Txhawm rau siv cov kab mob ntsev thiab cov phaj nyaj los ntawm Streptococcus pyogenes, thiab rau kev tiv thaiv kev ua npaws rheumatic, penicillin feem ntau yog kws kho mob. Nws yuav tsum raug sau tseg tias azithromycin yeej tiv thaiv cov kab mob hauv cov kab mob hauv streptococcal, tab sis nws tsis haum rau kev tiv thaiv kev ua npaws rheumatic.

Cov tshuaj "Zi-factor". Analogues

Nyob rau hauv ib zaug nws yog tsim nyog los hais tias "Z-factor" kev kho mob tsis yog thawj qhov kev npaj. Qhov no yog cov tshuaj tua hluavtaws sab hauv "Sumamed", tsim los ntawm 1980 los ntawm cov kws ua hauj lwm hauv Croatian lub tuam txhab "Pliva". Rau hnub tim, muaj ntau yam analogues ntawm Sumamed kev muag: nrog rau cov tshuaj Zi-Foob, lawv muaj xws li cov tshuaj xws li Azitrox, Hemomycin, Azitsid, Solutab Sumatrolide, Zitrolide, Azivok "," Safotsid "," Azitral "," Sumamox "," Sumamechin "thiab lwm tus. Li ntawd, puas muaj qhov sib txawv ntawm qhov yuav tsum siv: cov generic "Zi-factor" lossis "Sumamed", uas yog thawj cov tshuaj? Tsis muaj ib lo lus teb rau lo lus nug no. Raws li lub pharmacological thaj chaw ntawm cov tshuaj no zoo tib yam, qhov txawv yog tsuas yog nyob rau hauv lub khw thiab tus nqi. Txawm li cas los xij, ntau tus neeg mob ntseeg tau hais tias qhov analogue yog txhais tau hais tias phem tshaj qhov qub, vim hais tias nws tsis ua kev soj ntsuam kev sim thiab kev sim. Yog hais tias koj kub siab rau tus nqi, nws yog qhov zoo dua yuav tus "Z-factor": tus nqi ntawm cov khoom siv rau cov khoom nruab nrab ntawm cov khoom hnyav 171-187 txhawm rau, thaum lub caij nyoog uas muaj "Six Sumamed" koj yuav tsum them 448-530 rubles.

Cov tswvyim ntawm cov neeg mob txog kev npaj "Zi-factor"

Cov neeg cov lus hais txog cov tshuaj no feem ntau zoo. Feem ntau ntawm cov neeg uas tau siv cov tshuaj, ntawm nws cov txiaj ntsig zoo, raug sau tseg rau kev ua haujlwm siab ntawm ib tus nqi qis dua. Cov neeg mob ua tim khawv tias cov tshuaj no zoo tshaj plaws rau tus mob angina. Nws xav zoo dua hnub tom qab noj tshuaj, muaj mob caj pas, hnoos, mob ib ce. Tsis tas li ntawd, cov tshuaj zoo txo cov kab mob sinusitis: nyob rau hnub thib ob ntawm kev kho mob, qhov ntswg qhov ciaj pliaj raug muab tshem tawm, thiab mob taub hau cease. Meanwhile, tsis yog txhua qhov kev kuaj xyuas yog qhov zoo. Qee tus neeg tham txog kev loj hlob ntawm kev muaj zog hauv plab hnyuv ntxig tsis zoo rau cov keeb kwm ntawm kev noj tshuaj Zi. Cov neeg mob tsis nco qab tias tom qab siv tshuaj capsules / ntsiav tshuaj, lawv pib muaj kev phem: cov tsos mob xws li kev poob siab, tsis muaj cua, lub plawv dhia ceev ceev, ntxhov siab vim, muaj kev ntshai nyob ntawm. Thaum zoo li no, koj yuav tsum tsis txhob noj cov tshuaj thiab nrhiav kev pab los ntawm ib tus kws kho mob tshwj xeeb.

Lus Qhia Ntxiv

Cov tshuaj "Zi-factor" los ntawm cov chaw muag tshuaj yog tso rau hauv cov tshuaj. Cov tshuaj tsis cuam tshuam qhov kev muaj peev xwm tswj cov mechanisms thiab cov tsheb. Txee lub neej txij hnub tso tawm yog ob xyoos, cov tshuaj yuav tsum muab cia rau ntawm cov menyuam yaus thiab tiv thaiv kom tsis txhob raug tshav ntuj ntawm qhov kub tsis tshaj 25 degrees Celsius.