Topiramate: cov lus qhia siv, kev txheeb xyuas rau cov yastes yau, cov analogues

Mob ntawm lub paj hlwb cuam tshuam rau lub functionality ntawm tag nrho cov kab mob. Piv txwv li, yog hais tias xws li ib tug kab mob zoo li qaug dabpeg, tus neeg tau txais ib lub neej tsis taus. Lawm, nrog rau qhov no pathology muaj lossi tua los txo cov xwm txheej ntawm los yog los mus tiv thaiv cov manifestation ntawm tawm tsam. Kev npaj "topiramate", cov lus qhia rau kev siv ntawm uas yuav teev muaj hereinafter, cia li rau kev kho mob ntawm no pathology. Nyob rau hauv tas li ntawd, nws yuav siv tau los tua lwm cov kab mob. Cov khoom no yog npaj rau cov sij hawm ntev siv.

General hauj lwm ntawm cov kev npaj thiab muaj pes tsawg leeg

"Topiramate", cov lus qhia rau kev siv ntawm uas yuav tsum tau ua tib zoo piav qhia rau tus neeg mob, nws yog ib qho antiepileptic neeg sawv cev uas yog siv rau cov nyem thiab kev tiv thaiv mob chua leeg hlwb. Nyob rau hauv feem ntau cov tshuaj ua nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, hauv uas muaj yog ib tug dawb hmoov. Ntsiav tshuaj nyob rau hauv sawv hlwv packs ntawm txiv kab ntxwv. Nyob rau hauv ib tug ntawm lawv muaj peev xwm muaj 25 los yog 10 mg ntawm active ingredient - topiramate. Tsis tas li ntawd, nyob rau hauv cov khoom nkag dihydrate calcium hydrogen phosphate, magnesium stearate, starch, hnyav magnesium hydroxycarbonate. Cov tshuaj yeeb dej caw yuav thaiv qhov kev txiav txim ntawm ob pulses thiab tiv thaiv kom txhob qaug dab peg.

Tom qab tus neeg mob yuav muab cov tshuaj yeeb dej caw, nws yog sai heev absorbed rau hauv lub plab thiab cov hnyuv. Nrog cov ntshav cov nqaijrog ntsiab active ingredient yog ua txhua yam los tsuas 13-17%. Qhov siab tshaj plaws pes tsawg tus ntawm topiramate nyob rau hauv cov ntshav cai tom qab 120 feeb. Feem siv yeeb tshuaj thiab nws cov metabolites yog ua mas nyob rau hauv cov zis. Ib nrab-lub neej yog 21 teev. Txawm tias qhov no lub sij hawm yuav tsum nce nyob rau hauv cov ntaub ntawv ntawm cov teeb meem nrog rau daim siab thiab ob lub raum.

indications

Yog hais tias koj tau raug tsa los ua cov tshuaj "Topiramate" phau ntawv qhia hais txog cov indications:

• Qaug dab peg provoked syndrome Lennox-Gastaut (raws li txhawb tus sawv cev).
• Lub ib feem los sis generalized tonic-clonic qaug dab peg (monotherapy).
• Qaug dab peg nyob rau hauv cov me nyuam los ntawm 3 xyoo thiab cov neeg laus (cov thawj txheej).
• Rau kev tiv thaiv ntawm migraine nyob rau hauv cov neeg laus.
• Neuropathy.
• Post-traumatic lub kev nyuaj siab.
• Haus dej cawv Syndrome.
• Manic-depressive psychosis daim ntawv.
• Bipolar tsis meej.

Cov tshuaj yog tau normalize lub mus ob peb vas. Raws li koj tau pom, "topiramate", cov lus qhia rau kev siv uas yog ib txwm nyob rau hauv lub pob nrog cov khoom, muaj ib tug me me rau ntawm daim ntaub ntawv. Txawm li cas los, txawm nyob rau hauv cov neeg mob nws yog tsim nyog yuav tsum tau ceev faj nrog nws txais tos, raws li cov tshuaj no yog suav tias yog muaj zog.

Contraindications thiab cov kev txwv txog kev siv

Txawm tias cov hauj lwm zoo ntawm no lub cuab tam, nws yog tsis pom zoo nyob rau hauv tej rooj plaub. Ntawm cov contraindications yuav qhia tau raws li nram no:

• Cov me nyuam uas muaj hnub nyoog (mus txog 2 xyoos). Cov tshuaj yog muaj zog dhau rau tus me nyuam lub cev.
• Intolerance txhais tau tias los yog ib co ntawm nws lub Cheebtsam.
• Thaum lub sij hawm uas cev xeeb tub thiab lactation. Lub ntsiab active ingredient yog tau txeem los ntawm tag nrho cov teeb meem nyob rau hauv niam cov kua mis.
• Nyiam tsim raum pob zeb.
• Loj inflammatory dab nyob rau hauv lub cev, mob mob pathologies.

Muab tshuaj "topiramate" migraine, tus kws kho mob yuav tsum ua kom tshwj xeeb attentive rau cov neeg cov neeg mob uas muaj teeb meem nrog lub raum muaj nuj nqi thiab daim siab. Tua tawm lub tsheb los ntawm lub cev nyob rau hauv cov ntaub ntawv no yog slowing, li ntawd, npaj txhij txog cov teeb meem yuav tshwm sim.

Yuav ua li cas tshwm sim muaj tshwm sim?

Yog hais tias koj tau raug tsa tshuaj "topiramate", cov kev qhia ntawv muab cov tsos ntawm cov nyom tshua:

• Kiv taub hau, mob taub hau, teeb meem tsis pom, hais lus tsis meej, nce nervousness. Nws yuav tshwm sim psychomotor ruamqauj, qaug zog, tsis muaj peev xwm mus mloog zoo.
• Somnolence, lub siab lub ntsws lability, kev nyuaj siab.
• Nyob rau hauv tsawg zaus, ib tug luv luv lub sij hawm nco tsis tau, tsis meej pem nco qab, disturbance ntawm saj nov ntawm nqaij tawv.
• Xeev siab thiab ntuav.
• Siab tsis ua hauj lwm.
• Tsis-kis tus kab mob siab.
• Poob phaus.
• Mob plab.
• Ua daus no.
• Tej zaum nws yuav ua rau kom qhov kub thiab txias.
• Qhaj ntawv ntawm kev coj khaubncaws, epistaxis, tej ntshav leukocytes.
• Nyob rau hauv tsis tshua muaj heev neeg mob, hallucinations zaum yuav tshwm sim.
• Txo muag pom acuity, thiab ib tug ua txhaum ntawm lub cev muaj zog muaj nuj nqi ntawm lub hnub nyoog (lawv tsiv mus nyob nthawv). Tsis tau muaj tej zaum yuav ib tus mob o ntawm lub conjunctiva.
• Cov pos hniav mob.
• Dryness nyob rau hauv lub qhov ncauj.
• Tsis libido nyob rau hauv cov txiv neej thiab cov poj niam. Cov yav tas los yuav txawm tua impotence.
• Gastritis thiab pais plab rwj.
• Zawv plab los yog cem quav.
• Halitosis.
• Nqaij mob, tsis muaj zog.
• Suab nrov los yog ringing nyob rau hauv lub pob ntseg, thiab tej zaum kuj tsis hnov lus.
• Kev ua txhaum ntawm kev sau ntawv thiab nyeem ntawv nyob rau hauv cov me nyuam.
• xws li loog loog ntawm extremities.
• Tseg txoj kev loj hlob nyob rau hauv cov me nyuam, weakening ntawm cov pob txha muaj zog.
• Cov kev tsis haum yog manifested nyob rau hauv daim tawv nqaij: khaus, tawm pob, hlwv.

Raws li koj tau pom, cov tshuaj "Topiramate" migraine kuj tau mus noj heev kom zoo zoo. Tshwj xeeb tshaj yog hnyav nws yog rau cov me nyuam. Yog li ntawd, peb yuav tsum nruj me ntsis raws li cov tshuaj. Nyob rau hauv cov ntaub ntawv no, ob leeg kws kho mob thiab niam txiv yuav tsum yeej ib txwm saib xyuas tus mob ntawm tus me nyuam.

Nta ntau npaum thiab daim ntawv thov

Taw qhia cov tshuaj tsuas yog ib tug kws kho mob. Self-pib nws txais tos yog tsis yooj yim sua, raws li muaj ib tug tau ntawm deterioration. Nyob rau hauv tas li ntawd, cov tshuaj no yog muag los ntawm cov tshuaj.

Yog hais tias koj muaj yam tshuaj ib txoj kev "Topiramate" qhia muab nws qhov ncauj kom tsawg, tsis hais rau hauv daim ntawv ntawm kev tso cai. Haus cov tshuaj yuav tsum tau muab qhia nrog rau cov khoom noj khoom haus, tshwj xeeb tshaj yog txij thaum nws tsis cuam tshuam rau kev txiav txim ntawm cov ntsiav tshuaj. Nws yog ntshaw kom tsim tau cov tshuaj nyob rau tib lub sij hawm. Koj yuav tsum tsis txhob zom los yog keej tshuaj, txij li thaum lawv muaj ib tug ntsim saj. Ntxiv mus, kev sib tsoo tshuaj yuav adversely cuam tshuam rau nws cov efficiency.

Thov rau cov khoom siv yuav tsum tau raws li nram no:

• Yog hais tias "topiramate" ntsiav tshuaj yog ib feem ntawm ib tug kev anticonvulsant txoj kev kho, txhua hnub tus nqi ntawm cov tshuaj yuav ntsuas 200-400 mg. Qhov no tus nqi yog feem ntau muab faib mus rau hauv 2 koob tshuaj. Nws yog qhov zoo tshaj plaws los pib kev kho mob nrog cov uas tsis muaj koob tshuaj (25-50 mg), uas yog npaum li cas rau 7 hnub txhua txhua hnub. Ntxiv mus, cov tshuaj yog maj zog rau 25 los yog 50 mg rau ib lub lim tiam los yog ob tug kom txog rau thaum lub zoo kom muaj nuj nqis, tso cai ib tug zoo ntxim. Siv cov tshuaj nyob rau hauv cov ntaub ntawv no, ob zaug ib hnub twg. Qhov siab tshaj plaws tshuaj uas neeg laus cov neeg mob tej zaum yuav noj txhua hnub, 1600 mg.
• Yog hais tias koj tus kws kho mob muaj kws kho ib tug me nyuam laus tshaj li 2 xyoos "topiramate", rau kev siv ntawm cov tshuaj no ua los ntawm cov nram qab no tswvyim: pib haus tshuaj xav tau ib koob tshuaj 25 mg ib hnub ob zaug. Tag nrho cov nqi ntawm cov kev npaj ib hnub twg yog 5-9 mg / kg lub cev hnyav. Nws yog qhov zoo tshaj plaws los mus thov lub tshuaj nyob rau hauv rau yav tsaus ntuj, ua ntej yuav mus pw, los txo cov kev pheej hmoo ntawm kev phiv. Lub hom chav kawm ntawm kev kho mob yog 7 hnub. Yog hais tias tsim nyog, lub ntau npaum rau ib los yog ob lub lis piam tsub kom los ntawm 1-3 mg / kg. Nkag yog muab faib ua 2 lub sij hawm.
• Yog hais tias cov tshuaj no yog siv nyob rau hauv monotherapy, tus kws kho mob yuav tsum qhia rau tus neeg mob sai sai. Nws yuav tsum tswj lub zaus ntawm ces qaug dab peg tom qab hloov anticonvulsant lwm yam tshuaj. Yuav tsum pib noj ib yam tsawg kawg nkaus tus nqi ntawm 25 mg ib hnub twg ib zaug ib hnub twg. Ntxiv mus, cov tshuaj yuav tau nce, tab sis nws yog ua li cas maj tshaj 1-2 lub lis piam.
• Yog hais tias tus neeg mob yuav tsis tso tej kev kho, nws siv yuav txo tau, los yog ncab lub caij nyoog mus ua kom txaus cov nqi.

Yuav kom qaug dab peg nqi yog tsis muaj zog, nws yog tsim nyog los nqa tawm lub abolition ntawm cov tshuaj maj. Txhua lub limtiam ntau npaum ntawm cov tshuaj yog txo los ntawm 100 mg.

overdose

Yog hais tias koj raug ib tug txhais tau tias ntawm "Topiramate" cov lus qhia rau kev siv (koj analogs sib tham tom qab) muaj nyob rau hauv kev txiav txim kom tsis txhob muaj lub txim los ntawm ntev txhaj koob tshuaj ntawm cov tshuaj. Txawm li cas los, muaj tej lub sij hawm thaum tus neeg mob vim yuav siv sij hawm cov tshuaj ntau tshaj li tsim nyog. Ces tej zaum yuav tuaj ib qho overdose.

Nws yog yus muaj los ntawm qaug dab peg zog, cov tsos ntawm tsaug zog, impaired lub zeem muag, kev sib koom tes thiab kev xav. Tau tshwm sim los ntawm ib tug overdose yuav amplified. Lawm, nyob rau hauv cov ntaub ntawv no nws yog tsim nyog los noj ceev kev ntsuas los pab tsis txhob tau txais ib tug loj npaum li cas ntawm ib yam khoom rau hauv lub mauj ncig.

Ua ntej ntawm tag nrho cov, koj yuav tsum hu rau ib tug tsheb thauj neeg mob. Tsis tas li ntawd, tus txheej txheem yog ua pais plab lavage. Tsis tas li ntawd, tus neeg mob yuav tsum noj tshuaj ntxeem tau dej "Enterosgel" tshuab txais carbon. Yog hais tias txoj hauj lwm yog hnyav heev, tus neeg mob urgently tsev kho mob. Kev tshem tawm cov cov tshuaj los ntawm cov ntshav los ntawm hemodialysis txoj kev siv.

Nta ntawm kev sis raug zoo nrog lwm yam tshuaj

Yog hais tias koj yuav tsum coj "Topiramate" phau ntawv qhia (lus yuav muaj cov tib yam ntxim rau lub cev) hais tias nws yog tsis tau tshaj rau tag nrho cov tshuaj. Piv txwv li, nws muaj peev xwm yuav ua ke nrog valproic acid "pentobarbital", "Carbamazepine". Cov tshuaj no yog npaj rau cov kev kho mob ntawm lub paj hlwb kev ntshawv siab. Joint txais tos ntawm xav muab tsis cuam tshuam rau lawv cov concentration hauv cov ntshav ntshav. Txawm li cas los, cov tshuaj "topiramate" yuav raug muab txo. Nyob rau hauv txhua rooj plaub, lub sij hawm ntawm cov tshuaj rau hauv lub neej coj kev kho mob, cov tshuaj ntawm tag nrho cov txhais tau tias tsim nyog kom tsim nyog kho.

Yog hais tias koj tus kws kho mob tau txiav txim siab los muab ib yam tshuaj nyob rau hauv ua ke nrog lub "pioglitazone", nws yog tsim nyog los saib xyuas tus neeg mob lub ntshav qab zib raws li txoj cai. Los ntawm combining "Topiramate" nrog "Metformin" tej zaum yuav tsis tau carbohydrate metabolism hauv lub cev. Co-thawj coj ntawm hais tias cov tshuaj nrog "acetazolamide" thiab nws cov analogues tsub kom kev pheej hmoo ntawm raum pob zeb.

Xav txog tseem lub fact tias nyob rau hauv thiaj li yuav ntxuav lub cev ntawm cov tshuaj thiab nws cov metabolites yuav siv sij hawm li ob peb hnub. Nyob rau hauv cov neeg uas muaj raum tsis ua haujlwm, lub sij hawm no yuav muab ntau zog ob zaug. Nws yog tsim nyog los paub, raws li nws yog tsim nyog yuav tau kho cov tshuaj. Tus nqi ntawm cov tshuaj tus kws kho mob suav nyob rau hauv txhua tus neeg cov ntaub ntawv.

ceev faj

Yog hais tias koj yuav tsum siv lub "Topiramate" ntsiav tshuaj (cov lus qhia rau kev siv yog lub ntsiab daim ntawv uas tswj cov tshuaj) yuav tsum tau qaug dej qaug cawv nyob rau hauv raws li cov lus qhia ntawm lub mus kawm tus kws kho mob. Txawm li cas los, muaj ib co tshwj xeeb cov lus qhia uas yuav tsum tsis txhob quav ntsej:

• Nyob rau hauv cov ntaub ntawv ntawm ntsoos ntsoos tsis tau ua nws dheev. Qhov tseeb hais tias muaj ib tug tau hais tias qhov zaus thiab siv cov kev qaug dab peg tuaj. Yog li ntawd, kom txhob muaj cov kev cai ntawm cov tshuaj yuav tsum tau ua maj.
• Ib tug ntawm lub sab los ntawm cov tshuaj tej zaum yuav anorexia, uas ua rau yus mus rau ib tug muaj zog havzoov ntawm lub cev vim poob phaus. Kom tsis txhob no, thov tham nrog ib tug kws qhia noj haus. Cov khoom noj yuav tsum tau tom li hais tias lub cev tau txais tag nrho cov tsim nyog vitamins thiab minerals rau kom zoo lag luam.
• Thaum lub sij hawm txoj kev kho yuav tsum tsis txhob noj psychoactive tshuaj thiab dej caw.
• Tshuaj "topiramate" (qhia ntawv, tswv yim, thiab muaj cov phooj ywg yog ib qho tseem ceeb cov ntaub ntawv rau tus neeg mob) muaj ib tug muaj zog cawv rau cov tshuaj tiv thaiv tus nqi, li ntawd, yuav tsav ib lub tsheb los yog ua hauj lwm txoj machinery thaum lub sij hawm kev kho mob yuav tsum tsis txhob yuav.
• Ntsiav tshuaj yuav tsum tsis txhob muab rau cov me nyuam nyob rau hauv lub hnub nyoog ntawm 2 hletnego.
• Nws yuav tsum tau ceev faj heev rau cov neeg cov neeg mob nyob rau hauv uas yog ib tug ua txhaum functionality raum thiab lub siab.
• Yog hais tias koj tsis nco qab mus noj ib ntsiav tshuaj nruj me ntsis rau lub sij hawm, sim haus thaum koj nco ntsoov. Txawm li cas los, Yog hais tias koj muaj lub sij hawm tuaj rau tom ntej no nkag, rau qhov catch-up yuav tsum tsis txhob coj ib tug muab ob npaug rau koob tshuaj. Nws yog zoo dua mus txuas ntxiv mus haus dej haus cov tshuaj rau cov hoob npaj.
• Txhim khu kev qha cov ntaub ntawv txog cov mutagenic kev txiav txim ntawm cov tshuaj nyob rau hauv tib neeg lub cev tsis yog. Txawm li cas los, nyob rau hauv kev kawm tshuaj nyob rau hauv nas provoked tsos ntawm hlav ntawm lub zais zis. Txawm li cas los, qhov no tau tshwm sim nyob rau hauv excess ntawm lub tso cai tus nqi, thiab nyob rau hauv uas tsis tshua muaj mob.

precautionary ntsuas

Yog hais tias koj noj cov tshuaj "Topiramate" phau ntawv qhia (xyuas ntawm cov tshuaj yuav kawm tom qab) qhia ib co kev ceev faj tias koj yuav tsum tau raws li nyob rau hauv kom tsis txhob tshwm sim kev phiv tshuaj:

• Yog hais tias tus neeg mob yog nyob rau kev lim ntshav, cov kev npaj rau lub zoo txiav txim yuav tsum tau xaiv ib nrab ntawm cov hnub koob tshuaj ua ntej cov ntshav purification txoj kev thiab tom qab nws.
• Thaum lub sij hawm tshem ntawm cov tshuaj yuav tsum nce dej kom tsawg. Qhov no yuav tiv thaiv tau cov deposition ntawm raum pob zeb.
• Yog hais tias muaj yog ib tug loj poob phaus, nws yog ua tau yuav tau kho cov kev noj haus thiab ntxiv kev pab noj haus uas txhawb qhov haum cov as-ham.
• Undesirably ua ke nrog "topiramate" txais tshuaj uas ntxias central lub paj hlwb kev nyuaj siab.

Raws li koj tau pom, cov tshuaj no yog heev loj heev, yog li ntawd koj yuav tsum tsis txhob self-medicate, vim hais tias koj yuav ua tau tej yam tuaj.

Nta Cia, analogs thiab xyuas

Yog hais tias koj yog sawv cev los ntawm txoj kev tsim, koj muaj peev xwm nug txog cov tshuaj analogs xws li "topiramate". "Topamax" cov lus qhia rau kev siv uas yog heev uas zoo sib xws rau lub yav dhau los piav qhia, yog ib tug ntawm lawv. Nws muaj tib lub active ingredient. Muaj lwm yam tshuaj analogues "Topsaver", "Toreal", "Maksitopir". Yeej switched, cov tshuaj tsis tau. Tej zaum lawv yuav tsis muab ib tug zoo ntxim, vim hais tias lawv muaj pes tsawg leeg tej zaum yuav txawv. Ua ntej koj yuav pib noj cov tshuaj muab yuav tsum tau nrog ib tug kws kho mob. Tshwj xeeb tshaj yog tsis muaj lawv cov tshuaj yog tsis zoo li ib tug neeg yuav sau.

Khaws cov tshuaj yeeb dej caw yuav tsum nyob rau hauv ib tug maub qhov chaw nyob qhov twg tsis txeem lub slightest ray ntawm lub teeb, dej. Tsis txhob muab tso rau qhov tshuaj deb ntawm chaw kub qhov chaw. Warranty lub sij hawm ntawm validity yog 2 xyoo. Tom qab lub sij hawm no, cov tshuaj yuav tsum tau muab pov tseg. Thiab qhov no yuav tsum tau ua li ntawd rau nws yuav tsis tau mus txog cov me nyuam.

Raws li rau lub xyuas, lawv yog cov sib txawv. Cov neeg mob nco ntsoov lub high efficiency ntawm cov tshuaj nyob rau hauv cov kev tswj ntawm qaug dab peg. Nws yog zoo heev rau yastes yastaw. Txawm li cas los, tus neeg saib xyuas muaj ib tug siab kuj nqi. Piv txwv li, tus nqi ntawm ib tug pob yuav ua tau 600 rubles thiab tshaj. Yog hais tias nws yog muaj tseeb siv yeeb tshuaj, nws yuav pab kom mus cuag long-term so ib pliag. Txawm hais tias muaj lwm yam kev xav. Piv txwv li, nyob rau hauv tej rooj plaub, cov me nyuam tau kev zoo nco thiab saib xyuas, kev loj hlob qeeb, thiab ib tug neeg tshuaj tsis pab. Muaj kuj yog deterioration lub xeev ntawm ob lub raum.

Nws yuav tsum tau muab sau tseg tias nyob rau hauv ib co thaj tsam ntawm lub teb chaws sawv cev los ntawm ib tug yeeb tshuaj yog muaj nyob rau ntawm cov tshuaj dawb, kev kawm mus rau tej yam kev zam. Tab sis ua ntej koj yuav tau ib lub cuab tam, koj yuav tsum tau nrog ib tug kws kho mob uas yuav muab kev tso cai. Nco ntsoov tias, nws tus kheej fraught nrog loj mob. Peb tau soj ntsuam cov nyhuv ntawm xws formulation li "topiramate", cov lus qhia, xyuas yastes yastaw thiab tshaj. Nrog ib tug kws kho mob thiab yuav noj qab nyob zoo!