Secondary hypothyroidism: Ua, Cov tsos mob thiab kev kho mob

Mob qaug zog, koj qhov hnyav nce, cov plaub hau tsis thiab nkig tes - cov no yog cov tsos mob paub kom ntau. Feem ntau cov feem ntau lawv muaj kev txhawj xeeb txog cov poj niam, tab sis tej zaum cai nyob rau hauv cov txiv neej. Nyob rau hauv tej rooj plaub, cov tsos mob no cia li tsis them sai sai. Qaug zog txuam nrog ib tug mus tas txoj hauj lwm, thiab qhov hnyav nce - malnutrition. Txawm li cas los, cov tsos mob no feem ntau qhia tias cov kev loj hlob ntawm no pathology li theem nrab hypothyroidism. Nyob rau hauv neeg laus, ib tug zoo xws li cov kab mob no yuav tshwm sim nyob rau hauv ib tug thaum daim ntawv. Cov tsos mob ntawm tus kab mob no yuav tsis meej pem nrog cov tsos mob ntawm lwm yam ailments. Tom qab tag nrho, hypothyroidism muaj feem xyuam rau yuav luag tag nrho cov lub cev. Kev kho mob ntawm tus kab mob tswj endocrinologist.

Congenital Hypothyroidism: ib tug piav qhia ntawm lub pathology

Congenital Hypothyroidism yog yus muaj los ntawm cov kev hloov nyob rau hauv hormonal theem txuam nrog impaired thyroid muaj nuj nqi los yog lub hlwb (pituitary). Tus kab mob yog yus muaj los ntawm ntau yam kev soj ntsuam ces, uas npog yuav luag tag nrho cov nruab nrog cev thiab tshuab. Nyob rau hauv cov kev phem ntawm cov kev hloov nyob rau hauv lawm ntau ntau, thyroid caj pas nyob rau hauv theem nrab hypothyroidism yog suav tias yog noj qab nyob zoo. Lub fact tias qhov no pathology muaj ib tug central keeb kwm. Nws muaj thaum ua txhaum los ntawm lub pituitary caj pas - ib tug endocrine hloov khoom nruab nrog, nyob rau hauv lub hlwb. Qhov no, nyob rau hauv lem, ua rau theem nrab txhab ntawm lub qog caj pas.

Secondary hypothyroidism yog feem ntau kuaj nyob rau hauv cov tub ntxhais cov neeg mob. Nws yog xav paub ntau ntau nrog cov poj niam. Ib qho txaus ntshai tus kab mob no pib rau cov me nyuam. Kuaj tej yam tshwm sim ntawm tus kab mob - yog ua rau kom cov theem ntawm TSH thiab ib tug nyiaj yuav txo tau nyob rau hauv tus nqi ntawm cov thyroxine (T4) thiab triiodothyronine (T3). Vim cov kev hloov nyob rau hauv lub pituitary caj pas tej zaum yuav muaj kawg ntawm lwm endocrine lug. Nyob rau hauv kev, adrenal caj pas, gonads, thiab hais txog. D.

Secondary hypothyroidism: cov ua ntawm tus kab mob

Cov ua rau lub pathology txuam nrog structural kev hloov nyob rau hauv lub hlwb cov ntaub so ntswg. Central genesis muaj thawj thiab hyperthyroidism. Yog li ntawd dab tsi yog qhov txawv ntawm lawv? Raws li yog lub npe hu, lub hypothalamic-pituitary system ntawm lwm yam uas tag nrho cov peripheral endocrine qog tam sim no nyob rau hauv lub cev. Nws yog nyob rau hauv lub hlwb. Lub ntsiab endocrine kev kawm ntawv yog lub hypothalamus. Qhov no hloov khoom nruab nrog yog nyob nruab nrab ntawm txoj cai thiab sab laug hemispheres ntawm lub paj hlwb. Yog hais tias koj ua txhaum lub tso pa tawm ntawm cov tshuaj hormones nyob rau hauv lub tuam tsev ntawm thawj hypothyroidism tsim. Lub hypothalamus ua biologically active tshuaj uas yog ces noj mus rau lub pituitary. Muaj tsim thyroid stimulating lawm (TSH). Lub pituitary caj pas muaj lub tswv yim mus rau lub endocrine kabmob, xws li cov thyroid. Yog li ntawd, los ntawm kev ua lub tso pa tawm ntawm TSH zus tau tej cov thyroxine thiab triiodothyronine txo.

Yog vim li cas yuav ua tau rau theem nrab hypothyroidism muaj xws li:

1. Inflammatory kab mob ntawm lub pituitary. Swb ntawm lub cev tej zaum yuav txuam nrog kab mob thiab kis encephalitis.
2. Congenital hypoplasia los yog tsis tuaj kawm ntawv ntawm lub pituitary caj pas.
3. Cancerous los yog benign qog.
4. Ischemic lub hlwb puas tsuaj.
5. Hemorrhage nyob rau hauv lub pituitary cheeb tsam.
6. Raug tawg thaum lub sij hawm irradiation ntawm lub paj hlwb hlav.
7. Atrophic kab mob.

Vim txoj kev loj hlob ntawm pituitary kev puas tsuaj tshwm sim theem nrab hypothyroidism. Tsis txhob xav yuam kev rau tus mob no nrog cov thyroid kab mob. Nrog lub yeej ntawm lub cev muaj yog ib tug tertiary hypothyroidism. Txawm li cas los ntawm lub etiology thiab kev kho mob ntawm hormonal ntshawv siab qhov twg los ntawm tus kab mob no ib endocrinologist.

Kev loj hlob ntawm postpartum hypothyroidism

Thaum lub sij hawm uas cev xeeb tub, lub cev yog ib tug ntau ntawm txawv hloov, mus rau ib tug ntau dua raws li lawv hais txog mus rau lub endocrine kheej. Qhov no yog vim lub fact tias ib txhia cov tshuaj hormones secreted los ntawm lub tsho me nyuam. Vim ib tug dhau heev lawm ntawm tej yam lom tshuaj nyob rau hauv lub cev ntawm lub tso pa tawm ntawm lub pituitary caj pas decreases. Conversely, ib tug txo nyob rau hauv zus tau tej cov tshuaj hormones ua hauj lwm pab raws li ib lub teeb liab mus rau kom lawv lawm nyob rau hauv lub hlwb. Raws li ib tug rau txim ntawm cov kev hloov no, ib txhia poj niam tsim theem nrab hypothyroidism tom qab tau me nyuam. Qhov uas nws tshwm sim yog ntau dua ntawm cov neeg uas nws cov ntshav muaj tshuaj tiv thaiv lub thyroid hlwb.

Autoimmune o ntawm lub endocrine hloov ua qhov ua kom ntawm lub pituitary caj pas. Thyroid-stimulating lawm pib yuav tsum tau ua sai sai thiab nyob rau hauv loj qhov ntau. Xws li ib tug lub xeev tom qab yug tus me nyuam yog suav tias yog ib ntus, uas yog transitory. Congenital Hypothyroidism tshwm sim nyob rau hauv cov poj niam tom qab 4-5 lub hlis tom qab yug tus me nyuam ntawm tus me nyuam. Feem ntau cov feem ntau, nws tsis muaj mob loj heev soj ntsuam daim duab. Txo nyob rau hauv cov thyroid hormones preceded los ntawm ib tug rov qab txheej txheem - thyrotoxicosis. Nws yog pom nyob rau hauv thawj lub hlis ntawm lub postnatal lub sij hawm. Thaum lub sij hawm hauv lub xyoo lub hormones rov qab mus rau qub. Yog hais tias nws tsis tau, ces, tus kab mob no tau coj qhov chaw thiab ua ntej cev xeeb tub, tab sis nws twb tsis qhia ua ntej lawm.

Nrhiav Congenital Hypothyroidism: Cov tsos mob thiab kev kho mob rau cov poj niam

Congenital Hypothyroidism ntawm central keeb kwm yog ntau heev nyob rau hauv cov poj niam. Cov tsos mob yog nyob ntawm seb heev ntawm hormonal tsis ua hauj lwm. Yuav ua li cas yog hypothyroidism? Cov tsos mob thiab kev kho mob ntawm cov poj niam, raws li yog cov ntaub ntawv nrog rau lwm cov pathologies txuas. Lub ntsiab yam tshwm sim ntawm lub xub ntiag ntawm tus kab mob:

1. Coj khaub ntshawv siab.
2. Nkees nkees.
3. Mob qaug zog.
4. Nkig rau tes thiab cov plaub hau.
5. Qhov nce nyob rau hauv lub cev hnyav.
6. Edematous syndrome.
7. Nyiam cem quav.

Nyob rau hauv tej rooj plaub, muaj tsuas yog ib co lus manifestation ntawm tus kab mob, thaum lwm tus neeg - tsawg pronounced. Tej zaum hypothyroidism yog asymptomatic. Feem ntau cov feem ntau, yog vim li cas rau kev kho mob nyob rau hauv lub tsev kho mob yuav nyhav dhau heev lawm, alopecia (cov plaub hau tsis) thiab cov lus hais rau edema syndrome.

hypothyroidism, kev kho mob yog pib nrog lub sij hawm ntawm hormonal tshuaj. Nyob rau tib lub sij hawm nrhiav kom tau qhov ua ntawm tus kab mob. Nyob rau hauv tej rooj plaub, hloov txoj kev kho no tsis yog lub thawj txoj kev ntawm kev kho mob.

Cov tsos mob ntawm hypothyroidism nyob rau hauv cov me nyuam

Secondary hypothyroidism nyob rau hauv cov me nyuam - qhov no yog ib tug txaus ntshai tus kab mob uas yuav ua rau hlwb ruamqauj, thiab ncua lub cev txoj kev loj hlob. Qhov tseeb hais tias cov thyroid hormones nyob rau ntawm ib thaum ntxov muaj hnub nyoog yog tshwj xeeb tshaj yog yuav tsum tau. Lawv muaj kev cuam tshuam cov txheej txheem ntawm txoj kev loj hlob thiab tsim ntawm txoj kev ntse. Tus kab mob tej zaum yuav tshwm sim los ntawm pituitary txawv txav, thiab txaus los khi kom tsawg ntawm iodine kas (rau tertiary hypothyroidism). Tsis hais txog ntawm qhov chaw hloov substitutive hormonal txoj kev kho yuav tsum tau pib kom sai li sai raws li lub kuaj nce nyob rau hauv lub concentration ntawm TSH.

Mob ntawm ob hypothyroidism

Raws li vyvit theem nrab hypothyroidism? Pathology kuaj pib nrog tus sau los ntawm kev tsis txaus siab thiab kev soj ntsuam ntawm tus neeg mob. Cov neeg mob feem ntau qhia ib qhov qaug zog thiab nkees nkees, koj qhov hnyav nce. Nco ntsoov lub ntsawj txias thiab qhov tshwm sim ntawm edema. Nyob rau hauv tej rooj plaub hypothyroidism kuaj ntawd, xws li thaum ua poj niam ncua tsis txheeb ze rau cev xeeb tub.

Nyob rau kev xeem qhia ib tug txo nyob rau hauv lub plawv dhia thiab hypotension. Edema yuav tsum tau nyob rau txhua qhov ntawm lub cev, feem ntau - nyob rau hauv lub ntsej muag. Palpation qhia hais tias lawv muaj ib tug mos mos taub hau mucosa (myxedema).

Qhov kawg mob yuav ua tom qab lub laboratory kev ntsuam xyuas. Nyob rau hauv cov neeg mob uas ntaus cim nce nyob rau hauv cov theem ntawm TSH thiab txo tus nqi ntawm cov thyroid hormones. Yuav kom qhia tau tias qhov ntawm tus kab mob yog nqa tawm radiography Sella, lub hlwb CT.

Txoj kev ntawm kev kho mob ntawm hypothyroidism

Secondary hypothyroidism ib tug hais rau heev hormonal txoj kev kho. Kev kho mob yuav tsum tau saib xyuas los ntawm ib tug endocrinologist. Txhua 3 lub hlis nqa tawm laboratory diagnostics los mus txiav txim seb cov TSH thiab thyroxine. Lub stabilization ntawm tej cim no yog lub qhia txog cov kev kho mob. Nrog rau cov theem siab ntawm TSH hormone koob tshuaj nce. Kev siv cov tshuaj "Eutiroks" thiab "Levothyroxine" raws li hloov txoj kev kho.

Nyob rau hauv tas li ntawd, nws yog tsim nyog los qhia qhov ua rau ntawm lub pathology. Nyob rau hauv inflammatory kab mob ua antibacterial thiab antiviral txoj kev kho. Nyob rau hauv tej rooj plaub, ib tug phais kho mob (adenoma thiab mob cancer ntawm lub pituitary caj pas).

Twv ua ntej thiab tiv thaiv teeb meem

Thaum qhov kev txais tos ntawm cov tshuaj hormones nyob rau hauv hypothyroidism huab cua paaj. Kom xaiv koob tshuaj yuav pab tau kiag li ntes cov tsos mob ntawm tus kab mob. Yuav kom tiv thaiv teeb meem yuav tsum tsis tu ncua tau soj ntsuam kuaj rau kev txiav txim ntawm TSH ntau ntau thiab cai ib endocrinologist. Ntawm nws tus kheej hloov ntau npaum cov tshuaj los yog kev kho mob yuav tsis rho.