"Monosan": cov lus qhia rau kev siv, tiag tiag counterparts

Yog vim li cas thiab nyob rau hauv dab tsi ntau npaum cov tshuaj cov tshuaj "Monosan"? Cov lus qhia rau kev siv ntawm vasodilator tshuaj yog piav nyob rau hauv kom meej nyob rau hauv cov ntaub ntawv ntawm qhov tsab xov xwm. Tsis tas li ntawd nws pib medicament analogs, nws muaj pes tsawg leeg, pharmacological los, contraindications, phiv, thiab hais txog. D.

Tus duab, ntim, muaj pes tsawg leeg

Yuav ua li cas tshuaj yog ib feem ntawm cov tshuaj "Monosan"? Instruction hais tias tam sim no lub caij ntawm cov tshuaj no yog isosorbide-5-mononitrate. Tsis tas li ntawd, lub medicament comprises ib pes tsawg leeg thiab xws li adjuvants: talc granulated lactose, magnesium stearate, microcrystalline cellulose thiab pob kws hmoov txhuv nplej.

Nyob rau hauv dab tsi daim ntawv manufacturers tsim tshuaj "Monosan"? Cov lus qhia rau kev siv hais tias ib tug yeeb tshuaj muaj peev xwm yuav yuav tsuas yog nyob hauv daim ntawv ntawm cov ntsiav tshuaj. Lawv yog cov dawb thiab hloov nyob rau hauv lub cev. Nyob rau ib sab ntawm cov ntsiav tshuaj muaj ib tug uas yuav muaj.

Cov tshuaj no yog fej nyob rau hauv blisters, uas yog nyob rau hauv lub teeb ntawm cardboard.

pharmacological nta

Yuav ua li cas puas cov tshuaj "Monosan"? Cov lus qhia rau kev siv ntawd hais tias cov tshuaj yog ib tug peripheral vasodilator, uas ua feem nyob rau hauv venous hlab ntsha.

Lub medicament yog tau mus tsim kho lub zus tau tej cov vascular endothelium endothelial relaxing tau xws li nitrogen oxide. Raws li ib tug tshwm sim ntawm zoo li no los yog ua kom cov soluble guanylate cyclase (intracellular enzyme) uas los ntawm nws tus kheej tsub kom lub vasodilating kho kom haum xeeb - cyclic guanosine monophosphate.

Tom qab noj cov tshuaj hauv lub hlwb thiaj li myocardial oxygen thov. Qhov no yog vim ib tug txo nyob rau hauv kev ua tau zoo thiab post-preload.

Tsis tas li ntawd, tshwj xeeb tau sau npe ib tug qhia cov nyhuv koronarorasshiryayuschee tshuaj.

tshuaj los

Yuav ua li cas lwm yam yeeb tshuaj muaj zog "Monosan"? Kev siv cov tshuaj no yuav txo tau cov ntshav khiav mus rau sab xis atrium, uas ho thiaj li lub siab nyob rau hauv lub ntsig txog kev thiab thiaj li heev ntawm qhov tsis zoo cov tsos mob ntawm pulmonary edema.

Nws yuav tsum tau muab sau tseg tias nyob rau hauv tus ntawm "Monosana" nyob rau hauv cheeb tsam uas muaj neeg txom nyem kev muaj yog ib tug redistribution ntawm coronary ntshav txaus

Nyob rau hauv keeb kwm yav dhau ntawm cov tshuaj nyob rau hauv cov neeg uas muaj angina thiab ischemic plawv tus kab mob, ho tsub kom kuj rau tej lub cev ua si. Nyob rau hauv tas li ntawd, cov kev kawm neeg sawv cev muaj peev xwm sawv ntawm tej lub Tx tsis Thrombocyte synthesis thiab inhibit platelet aggregation.

pharmacokinetic zog

Qhov uas nws yog absorbed, faib thiab metabolized tshuaj "Monosan"? Cov lus qhia nyob rau hauv daim ntawv thov hais tias qhov kev txiav txim ntawm cov tshuaj tshuaj es sai sai thiab tag nrho absorbed los ntawm lub digestive ib ntsuj av. Tom qab tau txais cov ntsiav tshuaj antianginal nyhuv muaj cai tom qab kwv yees li 30-45 feeb thiab khaws cia rau 10 xuab moos.

Raws li cov kws tshwj xeeb, tshuaj "Monosan" muaj ib tug ncaj high nqi ntawm bioavailability (kwv yees li 99-100%). Qhov no yog vim lub tsis tuaj kawm ntawv ntawm thawj pass ntawm cov tshuaj los ntawm lub hepatic system.

Lub ib nrab neej ntawm cov tshuaj yog 60 feeb. Lub concentration ntawm kev siv yeeb tshuaj nyob rau hauv cov ntshav mas nws txawv me ntsis, nyob ntawm seb tus neeg.

Metabolism hauv cov tshuaj active tshuaj nyob rau hauv lub siab. Raws li ib tug tshwm sim ntawm metabolic dab yog tsim ntawm peb lub Cheebtsam: isosorbide glucuronide thiab ob isosorbide-5-mononitrate.

ib nrab-lub neej lub sij hawm yog 4-5 teev. Thaum zoo li no 2.2% yog tas ntawm lub raum system thiab 97,8% - raws li glucuronic metabolites.

indications

Nyob rau hauv dab tsi tej yam kev mob yog muab rau "Monosan"? Kev siv cov tshuaj no yog zoo tshaj plaws nyob rau hauv cov nram no mob:

• pulmonary tawg, pulmonary lub plawv;
• mob ntaub ntawv ntawm txhaws lub plawv tsis ua hauj lwm;
• stenokardicheskie tiv thaiv mob chua leeg hlwb nyob rau hauv cov neeg uas muaj coronary artery kab mob.

Contraindications

Nyob rau hauv dab tsi tej yam kev mob yuav siv tsis tau "Monosan"? Analogs thiab hais tias txhais tau hais tias nws tus kheej yog txwv tsis pub mus yuav coj thaum:

• vascular cev qhuav dej;
• ib lub xeev ntawm poob siab;
• arterial hypovolemia thiab hypotension;
• mob tamponade ;
• tshuav ventricular tsis ua hauj lwm thiab tsis muaj indices ntawm diastolic ntshav siab;
• tshuaj lom pulmonary edema;
• mob theem ntawm myocardial infarction (nrog pronounced hypotension);
• daim ntawv-kaw glaucoma;
• kev pub niam mis;
• cov kab mob uas ntxias tus sawv ntawm intracranial siab;
• ib tug neeg npau taws me ntsis;
• nyob rau hauv cov me nyuam thiab cov tub ntxhais hluas (mus txog rau lub hnub nyoog ntawm feem ntau).

Nws yuav tsum tau muab sau tseg tias cov qhia txhais tau tias yog tus txheeb ze contraindications. Cov nram qab no mob siv rau lawv:

• mitral stenosis ;
• constrictive pericarditis;
• hnub nyoog laus;
• vascular mob orthostatic kev cai;
• raum insufficiency system;
• hypertrophic cardiomyopathy;
• hyperthyroidism;
• hepatic tsis ua hauj lwm ;
• aortic stenosis;
• muaj ntshav liab txaus li.

Tshuaj "Monosan": cov lus qhia rau kev siv

INN (International Nonproprietary lub npe) cov tshuaj no suab zoo li "isosorbide mononitrate." Qhov no tshuaj yog muab hais xwb. Raws li cov lus qhia, nws yuav tsum tau nqos tag nrho thiab ntxuav cia nrog dej.

Ntsiav tshuaj yuav tsum tau xaiv ib tug kws kho mob. Nyob rau tib lub sij hawm nws yog yuam ua hauj lwm rau kev ntsuam xyuas cov heev ntawm lwm tus kab mob ntawm nws tus neeg mob.

"Monosanom" Kev Kho Mob pib nrog txais txhais tau tias 10-20 mg 1-3 zaug ib hnub twg. Nrog 3-4 hnub ntawm txoj kev kho kev kho me ntsis yuav tsum tau ua noj regimen. Yog hais tias tsim nyog, tus nqi ntawm cov tshuaj muaj zog rau 20-40 mg thiab noj ob zaug ib hnub twg.

tsos mob ntawm overdose

Yuav ua li cas yog lub cim ntawm overdose yuav tshwm sim thaum ib tug neeg mob uas tau txais cov tsis ncaj ncees lawm tshuaj "Monosan"? Cov lus qhia rau kev siv qhia cov nram qab no cov tsos mob: lub cev qhuav dej, tsaus muag, raws plab syndrome, kiv taub hau, hyperpnoea, lossis puas liab liab ntawm daim tawv nqaij, cov me nyuam mos, dyspnea, tachycardia reflex keeb kwm, mob taub hau, pyrexia, nkees, tsis muaj zog, nce intracranial siab, visual ua cuam tshuam, qaug dab peg, tuag tes tuag taw, xeev siab, coma, tawm hws, ntuav.

Nyob rau hauv kev kho xws tej yam kev mob raws li yog siv rau cov manipulating pais plab lavage thiab muab enterosorbiruyuschee txhais tau tias.

phiv

Puas phiv tshuaj cov tshuaj tiv thaiv "Monosan"? Cov lus qhia rau kev siv (analogs ntawm medicament muaj qhia hauv qab no) muab hais tias xws li ib tug yeeb tshuaj tej zaum yuav ua rau cov tsos ntawm ib tug plurality ntawm sab-los. Peb hais ib co ntawm lawv:

• ntuav;
• hlawv nov ntawm nqaij tawv rau tus nplaig;
• qhov ncauj qhuav;
• xeev siab;
• kub flashes;
• tachycardia;
• nitrate mob taub hau;
• yaug kais dej ntawm daim tawv nqaij ;
• kiv taub hau;
• ntaus cim yuav txo tau nyob rau hauv cov ntshav siab;
• stenokardicheskie nce zaus ntawm qaug dab peg;
• Orthostatic hypotension ;
• hypersomnia;
• hlwb ruamqauj thiab lub cev muaj zog cov lus teb;
• nruj;
• qhov muag plooj tsis pom kev;
• tsim kom muaj kam;
• tej tawv nqaij ua pob ua xyua;
• exfoliative dermatitis.

Analogs ntawm cov tshuaj thiab nws cov nqi

Uas txhais tau tias koj yuav hloov tau cov tshuaj «Monosan"? Analogues ntawm cov tshuaj no muaj nyob rau hauv txhua txhua lub tsev muag tshuaj. Cov qhov zoo tshaj yog tau faib "Monocinque muab", "Izoket", "Kardiket", "Efoksa", "Pektrol".

Raws li rau tus nqi ntawm cov tshuaj, nws tsis yog heev. Tau tshuaj nyob rau hauv Lavxias teb sab lub zos tau tsuas yog rau cov 100s (30 ntsiav tshuaj).

Testimonials

peb xav tias yuav cov tshuaj muaj ib tug ntau ntawm cov zoo tswv yim. Cov neeg mob cam hais tias nws behaves raws li ib tug heev zoo neeg sawv cev rau koj muaj teebmeem kev tawg thiab mob hauv lub plawv tsis ua hauj lwm zoo lawm. Txawm li cas los, nws yuav tsum tau muab sau tseg tias rau tau siab kho tshwm sim xws li ib tug yeeb tshuaj yuav tsum tau ua ke nrog lwm yam tshuaj. Ua li no, nco ntsoov sab laj rau lub mus kawm tus kws kho mob.

Kuv kuj xav kom koj nco ntsoov hais tias muaj ntau cov neeg mob haum nqi xa los ntawm cov tshuaj. Raws li hais saum toj no, 30 ntsiav tshuaj koj yuav tau them xwb 100 Lavxias teb sab rubles.

Peb tsis tau hais tias hais txog cov tshuaj thiab feem ntau tawm tsis zoo lub tswv yim. Nyob rau hauv Feem ntau, lawv yog txuam nrog rau cov tsos ntawm ib tug plurality ntawm sab-los. Los ntawm txoj kev, thaum lawv tshwm sim los ntawm haus yuav tsum tau tso tseg thiab hloov los ntawm ntau ruaj ntseg txhais tau tias. Yuav ua li cas raws nraim, koj yuav tsum tau qhia rau tsuas yog ib tug tej tus kws khomob tshwjxeeb.