Loperamide hydrochloride. Loperamide hydrochloride - phau ntawv qhia

Yuav ua li cas yog cov tshuaj "Loperamide hydrochloride '? Ib tug kev lo lus teb rau lo lus nug no yuav muaj nyob rau hauv cov ntaub ntawv yog muab los ntawm tsab xov xwm. Nyob rau hauv tas li ntawd, peb yuav qhia rau koj nyob rau hauv kom meej txog yuav ua li cas coj cov tshuaj, thaum twg thiab nyob rau hauv dab tsi npaum li cas.

lus qhia dav dav

Lub medicament "Loperamide hydrochloride" yog ib tug symptomatic tshuaj uas yog feem ntau siv los kho mob thiab ntev raws plab. Qhov no tshuaj yog muag tsis muaj ib tug tshuaj thiab muag nyob rau hauv txhua lub chaw muag tshuaj nyob rau ntawm ib tus nqi pheej yig.

pharmacological los

Kev npaj "Loperamide hydrochloride" qhia uas yog nested nyob rau hauv lub thawv, thiaj li kom thiab suab nrov ntawm tus nqaij ntawm cov hnyuv thiab cheeb peristalsis ntawm lub cev, zoo heev ua lub transit lub sij hawm ntawm nws txheem. Yog li, lub hais medicament niamntiav antidiarrhoeal nyhuv. Nws yuav tsum tau muab sau tseg tias cov tshuaj "Loperamide hydrochloride" pib ua sai sai heev. Thaum txais tos ntawm cov tshuaj no hauv lub kho nyhuv tsuas kav txog 4-6 teev.

tshuaj

Xws li ib tug medicament yog absorbed nyob rau hauv cov hnyuv yog heev pluag (hais txog 40%). Vim lub high school lub zoo sib thooj mus receptors ntawm lub plab hnyuv phab ntsa, raws li zoo raws li ib tug high degree ntawm biotransformation ntawm thawj zaj los ntawm lub siab ntshav theem ntawm unmodified tivthaiv tom qab tau txais txhais tau tias 2 mg (1 capsule) yog tsawg tshaj li 2 ng / ml. Qhov siab tshaj plaws concentration ntawm lub active tshuaj tom qab siv cov tshuaj no mus txog tom qab hais txog 2.5 sij hawm, thiab tom qab lub tsiav tshuaj - tom qab 5 teev. Ruaj rau ntshav cov nqaijrog tshwm sim nyob rau hauv 97%. Qhov no tshuaj yog metabolized nyob rau hauv daim siab thiab yog muab tau los nyob rau hauv ib feem ntawm koj cov zis, raws li conjugates nrog cov kua tsib, raws li zoo raws li nrog cov quav.

Tso daim ntawv ntawm cov tshuaj thiab nws muaj pes tsawg leeg

Kev npaj "Loperamide hydrochloride," txoj kev siv cov uas yog tau piav hereinafter, yog marketed nyob rau hauv daim ntawv:

• Substance hmoov rau cov tshuaj.
• 2 mg ntsiav tshuaj, yog muab tso rau hauv lub thawv 50, 30, 20 los yog 10 daim.
• 2 mg tsiav tshuaj muab tso rau hauv lub hnab 30, 20 los yog 10 daim.
• Nkaws nyuaj tsiav tshuaj daj, uas muaj ib tug dawb cov hmoov muaj tus nquag tivthaiv - Loperamide hydrochloride. Txhua cov tshuaj ntsiav muaj 2 mg ntawm active tshuaj. Dhau li sawv cev medicament muaj nyob rau hauv nws cov muaj pes tsawg leeg thiab koom haum pab khoom xyaw: talc, pob kws starch, lactose, magnesium stearate thiab colloidal silica. Nkaws tsiav tshuaj yog muag nyob rau hauv ib tug thawv 20 los yog 10 daim.

Qhov twg lwm tus muaj lub active ingredient tshuaj Loperamide hydrochloride? Kev siv cov no substance nyob rau hauv pharmacology thiab tso cai rau cov tshuaj xws li "Imodium" thiab "Diara". Txawm li cas los, nws feem pua nyob rau hauv cov formulations yog npaum li cas me dua nyob rau hauv lub aforementioned medicament.

Tshuaj "Loperamide hydrochloride": li cas yog meant?

Raws li cov lus qhia, cov tshuaj yuav tsum tau siv sij hawm nyob rau hauv cov nram no mob:

• Yuav kom normalize lub rooj zaum ntawm ileostomy.
• Thaum metabolic mob thiab plab hnyuv haum, uas yog tshwm sim los ntawm cia li thiab drastic hloov nyob rau hauv cov zaub mov los yog cov ib txwm muaj pes tsawg leeg ntawm cov khoom noj (piv txwv li, thaum lub sij hawm noj cov zaub mov, nyob rau ib txoj kev taug).
• Raws li ib tug koom haum pab tshuaj nyob rau hauv kab mob raws plab.
• Raws li symptomatic kev kho mob rau mob los yog mob raws plab (tsis haum, tawg, tshuaj los yog lub siab keeb kwm).

Contraindications rau kev siv ntawm cov tshuaj

Nyob rau hauv tej rooj plaub, koj muaj peev xwm siv tsis tau cov tshuaj "Loperamide" (ntsiav tshuaj)? Cov lus qhia muab tshuaj lub xeev hais tias nws yog tsis pom zoo rau:

• plab hnyuv rhuav txhua;
• raws plab, uas tau arisen vim dysentery, mob pseudomembranous enterocolitis los yog lwm yam kab mob ntawm lub digestive ib ntsuj av tau;
• diverticulosis;
• mob ulcerative mob plab;
• npau taws me ntsis.

Nws yuav tsum tau muab sau tseg tias cov antidiarrheal tshuaj rau cov me nyuam yuav tsum tau kho xwb mus rau 4 xyoo. Nyob rau hauv tas li ntawd, raws li cov lus qhia, txhais tau tias "tshuaj Loperamide" yog ua rau cov thawj peb lub hlis uas cev xeeb tub thiab thaum lub sij hawm lactation. Nrog zoo saib xyuas cov tshuaj no yog tshuaj rau daim siab tsis ua hauj lwm.

Lub medicament "Loperamide hydrochloride": cov lus qhia rau kev siv

Ntsiav tshuaj thiab tsiav tshuaj ntawm cov tshuaj yuav tsum tau noj ntawm ncauj tsis muaj zom. Cov tshuaj ntawm cov tshuaj nyob rau hauv lub hnub nyoog ntawm tus neeg mob thiab kab mob heev.

Nyob rau hauv mob raws plab nyob rau hauv tus neeg laus raws li cov thawj koob tshuaj muab 4 mg ntawm cov tshuaj thiab ces - los ntawm 2 mg tom qab txhua defecation (yog hais tias tus lub rooj zaum yog tseem kua).

Nyob rau hauv ntev raws plab thawj koob tshuaj yog 2 mg. Supportive txoj kev kho rau cov neeg laus yuav tsum tau ua lub tsev li hais tias tus neeg mob lub quav zaus yog 1 los yog 2 lub sij hawm ib hnub. Qhov siab tshaj plaws txhua txhua hnub koob tshuaj - 16 mg.

Tus kho nyhuv ntawm kev noj xws li ib tug yeeb tshuaj muaj tsis pub dhau 48 teev. Yog hais tias, txawm li cas los, rau 2-4 hnub, siv txog li 16 mg ntawm cov tshuaj txhua txhua hnub, koj yuav tsis tau cov kev kawm, koj yuav tsum nco ntsoov sab laj ib tug kws kho mob, uas muab lawv kom rov xyuas cov mob. Siv cov tshuaj yuav tau rov qab, tab sis tsuas yog ib txog kev kho los yog dieting tsis normalize lub rooj zaum.

Raws li rau cov me nyuam, xws li ib tug yeeb tshuaj yuav tsum tsuas yog siv 4 xyoo. Cov koob tshuaj yog tseem nyob rau hauv lub hnub nyoog ntawm tus neeg mob thiab cov heev ntawm tus kab mob no.

Cov me nyuam mos los ntawm 4 mus rau 7 xyoo, cov tshuaj yuav tsum tau muab 3-4 lub sij hawm ib hnub twg rau 1 mg. Duration ntawm kev kho yog 3 hnub. Cov me nyuam los ntawm 7 mus rau 12 xyoo muab plaub zaug ib hnub twg 1 ntsiav tshuaj rau 5 hnub. Nyob rau hauv mob raws plab pib ntau npaum me nyuam yuav tsum yog 1 capsule. Qhov siab tshaj plaws txhua txhua hnub koob tshuaj rau cov me nyuam - 8 mg.

Yog hais tias ib tug me nyuam muaj raws plab cai tom qab txhua yam uas defecation nyob rau hauv ib tug ntev lub sij hawm, txhua txhua lub sij hawm nws yuav tsum tau muab 1 capsule, tab sis tsis ntau tshaj li 6 mg ib 20 kg ntawm lub cev hnyav ib hnub twg. Yog hais tias tus me nyuam tsis mus rau lub tso zis tso ntau tshaj 12 teev, thiab tom qab normalization quav txais tos los ntawm cov tshuaj yuav tsum tau mus nres.

tshuaj overdose

Nyob rau hauv cov ntaub ntawv ntawm overdose nrog cov tshuaj no nyob rau hauv ib tug neeg mob li nram qab no hloov tau cai:

• teeb nyob rau hauv lub sib haum ntawm taw;
• constriction ntawm cov tub kawm ntawv;
• stupor;
• nkees nkees;
• nce skeletal leeg laus;
• plob tsis so tswj rhuav txhua;
• ua pa nyuaj siab.

Yuav kom kho xws li pathological lub xeev cov kws kho mob feem ntau cov tshuaj "Naloxone" yog siv nrog simultaneous symptomatic txoj kev kho.

phiv

Nws yuav tsum tau muab sau tseg tias tom qab daim ntawv thov ntawm cov kev npaj "Loperamide hydrochloride" cov neeg mob tej zaum yuav muaj nyias kev phiv. Heev feem ntau lawv tshwm sim nrog heev siv ntawm cov tshuaj. Yog li sawv cev medicament tej zaum yuav ua cov nram qab no tshwm sim tsis zoo:

• flatulence;
• ntsha txawv txav;
• ntuav;
• plab hnyuv tu-sauv;
• kiv taub hau;
• gastralgia;
• xeev siab;
• hypovolemia;
• nkees nkees;
• qhov ncauj qhuav.

Nyob rau hauv cov me nyuam yaus, ib tug yeeb tshuaj feem ntau ua rau tsis xis nyob nyob rau hauv lub plab mog, raws li zoo raws li cov tawv nqaij ua pob ua xyua. Heev tsis tshua medicament "Loperamide hydrochloride" tej zaum yuav ua rau kom mob txeeb qib qub los sis plab hnyuv dab tsi thaiv.

Yog hais tias tom qab 2 hnub no phenomena tsis ploj, thiab tus neeg mob tsis txhob xav tias zoo dua, koj yuav tsum nco ntsoov sab laj ib tug kws kho mob, uas yuav taw rau lwm yam (xws li) khoom. Yog hais tias ib tug yeeb tshuaj tsis pab, nws yog ib qhov zoo tshaj plaws los saib seb puas rau tus kab mob uas ua rau raws plab.

tshuaj cov kev sib tshuam

Raws li cov lus qhia, thaum lub sij hawm daim ntawv thov ntawm kev npaj "Loperamide hydrochloride" thiab "Cholestyramine" thawj efficiency yuav txo tau. Yog hais tias koj yuav tau siv cov tshuaj nrog cov txhais tau tias "Co-trimoxazole" los yog "Ritonavir", ces koj yuav tsum paub hais tias nws cov bioavailability yog ho muaj zog.

ceev faj

Tshuaj "Loperamide hydrochloride" yuav tsum tau noj nrog huab ceev faj nyob rau hauv hepatic puas. Nws kuj tsis pom zoo kom siv nws nyob rau hauv cov kev soj ntsuam lub sijhawm uas inhibition ntawm plab hnyuv peristalsis. Nyob rau hauv lub qhaj ntawv ntawm txaus kho nyhuv tom qab 2 hnub tom qab thawj coj ntawm cov tshuaj nws yog ntshaw kom kho qhov mob ntawm tus kws kho mob thiab tshem tawm cov kab genesis raws plab.