Glatiramer acetate: piav qhia tshuaj

Ntau sclerosis - ib tug loj heev kev puas tsuaj rau lub hauv paus poob siab system yeej ib txwm yuav tsum tau kho. Kab Mob raug neeg hluas thiab nruab nrab muaj hnub nyoog: at-uas yuav muaj pab pawg neeg no muaj xws li cov txiv neej thiab cov poj niam los ntawm 15 mus rau 40 xyoo. Ib tug ntawm cov txhais tau hais tias yog siv rau cov kev kho mob yog glatiramer acetate. Nyob rau nws yuav tsum tau los sib tham nyob rau hauv no tsab xov xwm.

Ntau sclerosis: mechanisms, ua, cov tsos mob

Ib tug txawv feature ntawm tus kab mob los ntawm lwm yam kab mob no yog hais tias nws muaj feem xyuam rau ntau qhov chaw ntawm lub paj hlwb, tiv thaiv uas tus neeg mob exhibits txawv neurological cov tsos mob. Remitting ntau yam sclerosis yog xam qhovkev rau: alternating lub sij hawm ntawm exacerbation thiab zam txim.

Lub impetus rau txoj kev loj hlob ntawm tus kab mob yog txoj kev puas tsuaj ntawm cov hlab week nyob rau hauv lub hlwb thiab tus txha caj qaum, ua nyob rau hauv ntau yam sclerosis (chaw zov me nyuam) lub tsim ntawm plaques. Lawv ntau thiab tsawg pab los ntawm ib tug ob peb millimeters mus rau ob peb centimeters. Thaum lub sij hawm exacerbations yuav rau kev kawm ntawv tshwj xeeb tshaj yog loj loj plaques.

Rau hnub tim, qhov ua rau ntawm tus kab mob no yog tsis qoos taub. Txawm li cas los, nws yog ntseeg hais tias ntau yam sclerosis yog txhais los ntawm ib tug ua ke ntawm sab nraud thiab sab hauv yam. Rau cov neeg muaj xws li:

• Nyhav rau kab mob (viral thiab kab mob).
• Raug tawg thiab tej yam tshuaj lom.
• Malnutrition.
• Geoecological chaw nyob.
• Nquag kev raug mob.
• Nquag stressful lub sijhawm.
• Caj predisposition.

symptomatology

Tus kab mob yog tsim los ntawm ib tug neurologist yog cov tsos mob tshwm sim:

• Tremor ntawm ob txhais tes, ob txhais ceg thiab lub cev. Tus neeg mob yog ib qhov nyuaj los tuav nyob rau hauv lawv txhais tes cov khoom, seb nws yog txawm tias ib tug diav los yog ib tug ballpoint cwj mem.
• Incoordination.
• Nystagmus - ceev ceev, tshwm qhov muag taw.
• Weakening (los yog tiav disappearance) reflexes.
• Cov kev hloov ntawm saj nyiam, poob phaus.
• Xws li loog loog, tsis muaj zog nyob rau hauv lub nqua.
• Kiv taub hau thiab lwm yam vegetososudistye kev ua txhaum.
• Paresis ntawm lub ntsej muag thiab trigeminal qab haus huv.
• Impotence nyob rau hauv cov txiv neej, coj khaub mob nyob rau hauv cov poj niam.
• Txo nyob rau hauv nrig txog kev pom pom tseeb tseeb.
• Qeeb hais lus.
• Dysmotility.
• Hlwb kev ntshawv siab (kev nyuaj siab, zoo siab, thiab li ntawd.).
• Epileptic qaug dab peg.

zoo

Muaj peb cov ntaub ntawv los ntawm ntau yam sclerosis:

• Hlwb txha nqaj qaum - lub feem ntau. Yus muaj los ntawm qhov txhab nyob rau hauv thaum ntxov ua sawv ntawm tus kab mob ntawm cov dawb teeb meem nyob rau hauv ob qho tib si txha caj qaum thiab lub hlwb.

• Cerebral - lub yeej ntawm dawb teeb meem ntawm lub paj hlwb. Nws muaj ob peb ntau yam - cerebellar, kav, cortex thiab qhov muag.

• Tus txha nqaj - txha caj lesion.

Glatiramer acetate nyob rau hauv ntau yam sclerosis

Xam tias yog medicament koom immunomodulators pab pawg neeg. Nruab nrab yog uskusnokisluyu ntsev tsim tej yam ntuj tso amino acids L-tyrosine, L-glutamic acid, L-alanine, L-lysine. Cov tshuaj hloov lub sij hawm tus kab mob no, muaj ib lub zos immunomodulatory nyhuv. Kev siv cov glatiramer acetate thiab yog thaum lub sij hawm txoj kev zam txim, txij thaum nyob rau cov ntaub ntawv no txhais tau tias thiaj li lub zaus ntawm exacerbations thiab kuj cheeb qhov uas cov kev loj hlob ntawm neurological ntshawv siab.

indications

Indications rau kev siv ntawm cov tshuaj yog tsis ntau. Cov muaj xws li:

• Remitting ntau yam sclerosis. Nyob rau hauv cov ntaub ntawv no, glatiramer acetate yog siv los txo exacerbations thiab deceleration ntawm cov yam ntxwv mob mob.
• Clinically cais Syndrome, tswv yim nrog rau cov simultaneous pronounced o yuav tsum tau tso dej corticosteroids. Nyob rau tib lub sij hawm tshuaj siv los qeeb rau txoj kev hloov ntawm tus kab mob nyob rau hauv ib tug kom meej meej pom tias ntau yam sclerosis.

Contraindications

Raws li yog cov ntaub ntawv nrog rau feem ntau cov tshuaj, siv cov glatiramer txwv tsis pub:

1. Yog hais tias ib tug neeg mob yog hypersensitive mus rau yeeb tshuaj (xws li ib tug mannitol).
2. Thaum lub sij hawm uas cev xeeb tub thiab lactation.
3. Mus txog rau 18 xyoo ntawm lub hnub nyoog (miv nyuas siv zug thiab kev nyab xeeb tsis tau kawm).

Nyob rau hauv tas li ntawd mus rau cov contraindications, muaj ntau cov kev txwv. Piv txwv li, yog hais tias tus neeg mob muaj ib tug predisposition mus rau ntau yam hom ntawm kev ua xua, raws li zoo raws li pathologies ntawm lub circulatory system thiab tej mob ntawm ob lub raum kev siv ntawm cov tshuaj yog ua tau, tiam sis tsuas yog nyob rau hauv huab mob thiab nyob rau hauv kev kho mob saib xyuas.

phiv

Phiv tshua rau kev siv ntawm cov tshuaj raws li ib yam khoom xws li glatiramer acetate, ib tug ntau ntau yam. Yog li ntawd, lawv muab faib ua tej pawg:

1. Immune System: meem kev txhawj xeeb, anaphylactic poob siab, angioedema.
2. Hematopoietic system: cov tshwm sim ntawm cov kab mob xws li leucopenia, leucocytosis, lymphadenopathy, hloov nyob rau hauv tus qauv ntawm lymphocytes, thrombocytopenia thiab splengomegaliya.
3. Endocrine system: hyperthyroidism.
4. Lub paj hlwb: tau mob taub hau, kev nyuaj siab, ntxhov siab vim, nervousness, zoo siab, convulsions, impaired lub cev muaj zog muaj nuj nqi, stupor, thiab li ntawd.
5. Los ntawm ib tug metabolism: nws muaj peev xwm muaj cai raws li ib qho kev nce nyob rau hauv lub cev hnyav, thiab anorexia. Nyob rau hauv tas li ntawd, tej zaum yuav muaj hyperlipidemia, hypernatremia, gout.
6. Tsis hnov lus, mob taub hau.
7. Kabmob uas tsis pom kev: diplopia, corneal kev puas tsuaj, cataracts, optic Atrophy, kho raws nyob rau hauv teb uas tsis pom kev, qhov muag plooj tsis pom kev.
8. Plawv system: tachycardia, paroxysmal tachycardia, varicose leeg, muaj ntshav siab.
9. Digestive system: xeev siab, ntuav, mob plab, belching, qhov quav los ntshav thiab li ntawd.
10. Ua pa system: hnoos, raws caij nyoog rhinitis, ua tsis taus pa, hyperventilation. Laryngospasm.
11. Daim siab thiab biliary txoj kev: cholelithiasis.
12. Mob txeeb system: pollakiuria, hematuria, urinary tuav tseg.
13. Subcutaneous cov ntaub so ntswg thiab daim tawv nqaij khaus, hu rau dermatitis, urticaria, erythema nodosum thiab li ntawd.
14. Licas System: arthralgia, rov qab mob thiab lub caj dab, mob caj dab, bursitis, osteoarthritis, thiab li ntawd.
15. Qau thiab mammary qog: lub cev ntas, kom nyob rau hauv lub mis mob cancer, erectile kawg.
16. Ua daus no, nkees, qhov ntswg los ntshav, kub taub hau, o, nqaij doog thiab thiaj li nyob. Tsos mob.

Sis nrog Drug

Lo lus nug txhais tau tias kev sis raug zoo nyob rau hauv lub hauv paus ntawm glatiramer acetate nrog lwm yam tshuaj twb tsis tau kawm txog rau thaum xaus. Sib tshuam nrog cov simultaneous siv rau cov tshuaj siv los kho ntau yam sclerosis, nws yuav tsis qhia (raws li nyob rau hauv lub neej coj kev siv ntawm cov saum toj no cov neeg ua hauj rau 28 hnub). High yuav ntawm lub zos haum tshuaj loj.

overdose

Rau hnub tim, cov ntaub ntawv nyob rau hauv cov nyom tej xwm txheej nrog ib tug overdose ntawm cov tshuaj tsis yog. Yog hais tias tag nrho cov tib teeb meem tshwm sim, tus neeg mob yuav tsum tau nyob rau hauv ze kho mob saib xyuas. Yuav tsum cov kev mob ntawm tus neeg mob, raws li tau zoo raws li muab symptomatic thiab txhawb kev kho mob.

Glatiramer acetate: cov lus qhia rau kev siv

20 mg ntawm cov tshuaj muab subcutaneously ib hnub ib zaug. Nws yog ib advisable kom mus rau lub sij hawm: lub txhaj yog pom zoo kom muab tso rau hauv tib lub sij hawm. Yog hais tias yog vim li cas lub sij hawm yog tsis tau, ces cov tshuaj yuav tsum nkag mus rau tam sim ntawd kom sai li sai raws li koj nco ntsoov. Ib tug muab ob npaug rau koob tshuaj yuav tsum tsis txhob yuav stabbing.

Muab tshuaj yog tau tso cai nyob rau hauv lub pob tw, lub duav, thiab ob txhais tes thiab lub plab mog (paraumbilical qhov chaw ntawm ib tug deb ntawm 5 cm). Lub bloodshot thiab sis tsuas kob daim tawv nqaij chaw thiab cov cheeb tsam nrog cov ntsaws ruaj ruaj tshuaj tsis txhob muab. Siv ib tug kev txiav txim siab kom txhob cov kev kho mob yuav tsum tau ib tug kws kho mob.

cov hauj lwm zoo

Yog nws zoo glatiramer acetate? Xyuas muaj ntaub ntawv hais txog cov feem ntau zoo tau nyob rau hauv thaum ntxov ua sawv ntawm lub sib ntaus tawm tsam ntau yam sclerosis. Feem ntau cov neeg muaj kev phiv tam sim ntawd tom qab kev txhaj tshuaj ntawm cov tshuaj. Txawm li cas los, lawv yog cov luv luv ntev thiab yog lawv tus kheej. Yog hais tias koj muaj kev mob loj, sai li sai tau sab laj ib tug kws kho mob, thiab nyob rau hauv tej rooj plaub - hu tsheb thauj neeg mob.

Nyob rau hauv tsawg tus neeg mob, mob thawj coj ntawm cov tshuaj tej zaum yuav tsim daim tawv nqaij necrosis thiab lipoatrophy ntawm lub qhov koob. Yuav kom tiv thaiv xws txim yuav tsum tau tsuas ua raws li cov theem ntawm lub cev qhov chaw cov kev txhaj tshuaj.

Trade lub npe, chaw tsim tshuaj paus

Glatiramer acetate muaj ib tug txawv luam lub npe. Tab sis tom qab ntawd rau hauv no. Rau ib ntev lub sij hawm, ua ntej txiav ntawm daim ntawv cog lus nrog rau cov Israeli lub tuam txhab, Teva tus neeg muag khoom, cov khoom no yog marketed Ltd. "Biotech". Glatiramer acetate yog tam sim no muaj los ntawm feem ntau Teva Lavxias teb sab lub tuam txhab "Teva".

Appointing ib tug yeeb tshuaj rau ntau yam sclerosis, tus kws kho mob feem ntau yuav qhia lub npe ntawm daim ntawv qhia yog: "Copaxone Teva." Txawm li cas los, qhov no yog tsis tsuas txhais tau tias, lub ntsiab active tshuaj yog glatiramer acetate. Analogs yog thoob plaws, no muaj xws li:

• "Copaxone 40".
• "Glatirat".
• "Aksoglatiran FS".
• "Timekson".

Yuav ua li cas yog qhov txawv txhais tau tias "Copaxone Teva" thiab "Copaxone 40" yog, nyob rau hauv qhov tseeb, ib tug thiab tib yam txhais tau tias? Lub active tshuaj nyob rau hauv lawv Attendance - glatiramer acetate. Txhais yog cov sib txawv ntau npaum thiab chaw pib lub khw muag khoom muaj nqi.

Nco ntsoov mus rau lawv noj qab haus huv, nyob rau hauv lub sij hawm mus rau tus kws kho mob thiab saib xyuas txog cov neeg uas!