"Fortum yog": cov lus qhia rau kev siv. Nqe, qhov chaw, xyuas, analogues ntawm cov tshuaj

Vim li cas peb yuav tsum tau ib tug kho "Fortum"? Cov lus qhia nyob rau kev siv ntawm cov nyiaj, nws muaj pes tsawg leeg, ntim thiab tso tawm daim ntawv no yuav tsum tau nthuav tawm nyob rau hauv no tsab xov xwm. Tsis tas li ntawd tawm ntawm nws, koj yuav kawm tau tias qhov no yog ib tug yeeb tshuaj uas nws muaj mob tshwm sim thiab contraindications, muaj muaj analogues ntawm cov tshuaj, thiab ntau npaum li cas nws cov nqi.

Muaj pes tsawg leeg thiab rau hauv daim ntawv ntawm ntim

koj muaj peev xwm yuav kho ntaus ntawv "Fortum" Nyob rau hauv dab tsi daim ntawv no? Tshuaj, peb xav, yog muag nyob rau hauv cov hmoov daim ntawv no. Nws yog siv rau kev npaj ntawm txhaj tshuaj. 1 raj mis muaj ib tug yeeb tshuaj acting caij xws li ceftazidime (nyob rau hauv daim ntawv ntawm cov pentahydrate). Nrog kev xav txog cov me Cheebtsam, ces lawv muaj xws li anhydrous sodium carbonate thiab carbon dioxide. Nyob rau hauv ib tug duab los qhia nras yog 1 vial.

Lub pharmacological cov yam ntxwv ntawm cov tshuaj

Yuav ua li cas yog cov tshuaj "Fortum"? Cov lus qhia rau Siv hais tias qhov no cephalosporin tshuaj tua kab mob peb tiam. Nws muaj ib tug bactericidal nyhuv. Tau mus rau hauv lub cev, cov tshuaj muab lub synthesis ntawm cov cell phab ntsa ntawm microorganisms.

Cov tshuaj muaj ib tug broad spectrum ntawm kev txiav txim (nyob rau hauv particular antimicrobial). Nws tua kab mob los ntawm pathogens uas yog resistant rau gentamicin thiab lwm yam tshuaj tua kab mob teej tug mus rau lub aminoglycoside pab pawg neeg. Txawm li cas los, peb nco ntsoov tias cov tshuaj yog resistant rau feem ntau beta-lactamases.

Cov kev tshawb fawb qhia tias cov active tshuaj tshuaj active tiv thaiv kab-zoo poob lawm, Gram-tsis zoo thiab co kab mob, xws li kab mob los hais tias yog resistant rau ampicillin.

Nws yuav tsum tau muab sau tseg tias ceftazidime yog tsis active tiv thaiv methicillin-resistant staphylococci.

Tshuaj ntawm cov tshuaj

tshuaj "Fortum" sai npaum li cas yog nws ua hauj lwm? Tshuaj tua kab mob tom qab intramuscular los yog tso dej raws leeg thawj coj ntawm koob tshuaj 1 mg rau 500 g thiab sai heev kuaj nyob rau hauv cov ntshav ntshav. Thaum no concentration ntawm lub active tshuaj neeg muab txog 8-13 teev. Nrog hais txog cov koom haum uas cov nqaijrog, nws yog hais txog 10%.

Cov ntau ntawm active tshuaj nyob rau hauv excess ntawm lub MIC rau qhov cov ntau pathogenic cov kab mob yuav ua tau tiav nyob rau hauv cov kua tsib, pob txha ntaub so ntswg, hnoos qeev, lub plawv ntaub so ntswg, synovial, pleural, thiab peritoneal intraocular kua.

Kuv kuj xav hais qhov tseeb hais tias ceftazidime heev yooj yim penetrates los ntawm lub placental barrier thiab yog tas nrog niam cov kua mis. Nyob rau hauv lub qhaj ntawv ntawm o nyob rau hauv lub meningeal week medicament active caij sufficiently tsis zoo txeem tau cov BBB. Nyob rau hauv cov ntaub ntawv no txhais tau tias cov concentration nyob rau hauv lub hlwb txha nqaj qaum kua yog tsawg heev li.

Xam tias yog cov tshuaj tsis yog metabolized nyob rau hauv tib neeg lub cev. Lub ib nrab-lub neej ntawm medicament yog hais txog 2 teev. Ceftazidime tshwm nyob rau hauv cov zis nyob rau hauv unchanged daim ntawv.

Nws yuav tsum tau muab sau tseg tias tus nqi ntawm feem ntawm lub active tshuaj yog markedly txo nyob rau hauv lub raum ua hauj lwm.

Indications rau kev siv

Nyob rau hauv tej rooj plaub, muab tshuaj "Fortum"? Cov lus qhia rau kev siv muaj xws li cov nram qab no daim ntawv teev cov nyeem tej no:

• kab mob nyob rau hauv cov neeg uas muaj cystic fibrosis, raws li zoo raws li ua pa zig;
• mob loj heev kab mob, xws li nosocomial (peritonitis, Septicemia, meningitis, mob, kub nyhiab tus kab mob thiab kab mob nyob rau hauv cov neeg uas muaj nws txo qis kev tiv thaiv);
• lub qhov ntswg, mob caj pas thiab pob ntseg;
• nqaij mos, thiab daim tawv nqaij;
• mob txeeb zig;
• kab mob ntawm cov pob qij txha thiab cov pob txha;
• Mob huam kab mob, biliary ib ntsuj av tau thiab lub plab kab noj hniav;
• kab mob uas txuam nrog kev lim ntshav.

Tsis tas li ntawd, cov tshuaj yog nquag siv rau kev tiv thaiv ntawm cov kab mob tom qab prostate phais.

Contraindications rau kev siv ntawm

Nyob rau hauv tej rooj plaub, tshuaj yuav tsum tsis txhob muab "Fortum"? Cov lus qhia rau kev siv muaj cov nram qab no daim ntawv teev cov contraindications:

• nce rhiab heev ntawm tus neeg mob yuav ceftazidime, raws li zoo raws li lwm yam hais txog cov tshuaj;
• me nyuam mos cov me nyuam;
• nce tus neeg mob rhiab heev rau penicillin thiab cephalosporin tshuaj tua kab mob.

Tsis tas li ntawd nco ntsoov tias cov tshuaj no yog tshuaj nrog huab ceev faj rau cov neeg uas raum tus kab mob, hnyuv kab mob, thaum lub sij hawm cev xeeb tub, thaum lub sij hawm lactation, nyob rau hauv ua ke nrog nrog aminoglycosides thiab diuretics.

nyob rau kev siv ntawm medicinal khoom

Yuav ua li cas kom zoo zoo thov cov tshuaj "Fortum"? Tshuaj siv rau cov neeg mob nyob rau hauv ib tug neeg lub hauv paus. Lawv ntau npaum nyob rau hauv lub heev ntawm tus kab mob no, raws li zoo raws li localization, rhiab heev mus rau yeeb tshuaj, lub hom pathogen, tus neeg mob lub hnub nyoog thiab lub raum muaj nuj nqi.

Lub tshuaj no yog muab intravenously los yog intramuscularly sib sib zog nqus (nyob rau hauv lub sab ib feem ntawm tus ncej puab los yog cov sab sauv txheej quadrant ntawm lub gluteus Maximus). Tsis tas li ntawd lub Txoj kev lis ntshav tshuaj tej zaum yuav nkag tau rau hauv lub raj system.

Lub sij hawm ntau npaum ntawm cov tshuaj (nyiaj pab ntau tshaj) yog hais txog 6 g neeg laus taw 1-6 g tauj ib hnub intravenously los yog intramuscularly. Multiplicity ntawm koom haum saib xyuas - 2-3 lub sij hawm ib hnub twg.

Feem ntau cov feem ntau suav hais tias yog medicament yog muab 2 g ntawm ua mib ntawm 12 teev los yog 1 g txhua txhua 8 teev.

Yog hais tias tus neeg mob muaj mob loj heev kab mob thiab txo kev tiv thaiv, thiab kuj muaj neutropenia, ces nws yog muab tso rau 2 g ntawm yeeb tshuaj txhua txhua 8 los yog 12 teev. Nws tej zaum kuj yuav xaiv 3 g ntawm yeeb tshuaj txhua txhua 12 teev.

Raws li nrog rau kab mob ntsws txaus thiab mob txeeb zig, siv yeeb tshuaj "Fortum"? Analogs txhais tau tias nws tus kheej thiab cov tshuaj yog muab nyob rau hauv ib tug ntim ntawm 1 ml los yog 500 g txhua txhua kaum ob teev.

Rau cov kev kho kab mob nrog xws li deflection li cystic fibrosis, cov tshuaj no yog siv nyob rau hauv ib tug npaum li ntawm 100-150 mg ib kg ib hnub twg (muab faib ua 3 lub sij hawm).

Thaum lub sij hawm kev phais rau cov prostate caj pas medicament yog siv nyob rau hauv ib tug ntau npaum ntawm 1 g ntawm induction ntawm tshuaj loog, ib tug thib ob koob tshuaj yog muab thaum lub sij hawm tshem tawm ntawm lub catheter.

Cov laus cov neeg mob (tshwj xeeb tshaj yog cov neeg laus tshaj 80 xyoo), cov tshuaj yog tshuaj nyob rau hauv tus nqi ntawm cov tsis ntau tshaj 3 g ib hnub twg.

Cov me nyuam laus tshaj 2 lub hlis ntawm tshuaj muab nyob rau hauv ib tug ntau npaum ntawm 30-100 mg rau ib kg ib hnub twg. Thaum zoo li no magnification yog thawj coj 2-3 lub sij hawm.

Cov me nyuam mos nrog meningitis, cystic fibrosis, los yog immunocompromised muab rau 150 mg rau ib kg ib hnub twg. Qhov siab tshaj plaws tshuaj yog 6 g (faib los ntawm 3 lub sij hawm).

Cov me nyuam mos thiab me nyuam mos cov me nyuam nyob rau hauv lub hnub nyoog ntawm ob lub hlis, cov tshuaj yog tshuaj xwb nyob rau hauv tus neeg mob. Ntxiv mus, nws ntim yuav tsum tau 25-60 mg ib kg ib hnub twg (muab faib nyob rau hauv ib nrab).

Cov neeg uas raum tsis ua hauj yuav tsum tau ib tug txo ntau npaum ntawm neeg sawv cev, raws li ceftazidime outputted los ntawm ob lub raum nyob rau hauv unchanged daim ntawv. Cov thawj zaug koob tshuaj rau cov neeg mob no yog 1 g Nrog hais txog qhov ntim ntawm cov nyiaj them yug, nws yog xaiv ib lub zuj zus (nyob ntawm seb lub glomerular filtration rate).

overdose

Tsis muaj teeb meem kim los yog pheej yig tshuaj uas koj siv los kho mob. Nyob rau hauv txhua rooj plaub, lawv yuav tsum tau tsuas yog siv rau cov tshuaj.

Yog hais tias qhia ib tug tshuaj tua kab mob siv los nyob rau hauv ib tug muaj zog npaum li cas, ces koj khiav txoj kev pheej hmoo ntawm overdose nram qab no cov tsos mob: neurological mob, xws li mob chua leeg, coma thiab encephalopathy. Nyob rau hauv kev kho xws tej yam kev mob raws li cov kws kho mob pom zoo kom ib tug symptomatic thiab txhawb txoj kev kho.

Tshwm sim los ntawm cov tshuaj

Pheej Yig tshuaj, nrog rau kim hais txog tshuaj tua kab mob, muaj ib tug ncaj loj tus naj npawb ntawm cov kev phiv. Xav txog daim ntawv teev cov lawv.

• Plab zom mov: xeev siab, Candidiasis ntawm lub qhov ncauj kab noj hniav thiab lub caj pas, jaundice, raws plab, mob plab, ntuav thiab nraum nce nyob rau hauv cov kev ua ntawm GGT, LDH, AST, ALT, thiab ALP. Tsis tas li ntawd, raws li nrog rau lwm cov cephalosporins, active tshuaj yuav ua rau pseudomembranous mob plab.
• Central thiab peripheral tshee system: paresthesia, mob taub hau, kiv taub hau, dysgeusia, neurological mob, xws li tshee, convulsions, myoclonus, encephalopathy thiab coma.
• hemopoietic system: leukopenia, eosinophilia, lymphocytosis, neutropenia, thrombocytopenia, agranulocytosis, hemolytic anemia, thiab thrombocytosis.
• Mob txeeb System: ntxaug ntawm ob lub raum, nraum nce nyob rau hauv urea thiab urea nitrogen thiab creatinine nyob rau hauv cov ntshav.
• Kev ua xua: txos cov ntshav siab, maculo-papular pob, kub taub hau, urticaria, bronchospasm, pruritus, angioedema, erythema multiforme, xws li Stevens-Johnson syndrome, epidermal necrolysis lom (ie Lyell tus syndrome).
• Local Phiv tshua: thrombosis los yog phlebitis (tso dej), kev sib khi ntawm lub intramuscular txhaj tshuaj, cov kev mob thiab kub.
• Lwm yam: Direct Coombs 'xeem (cuav zoo) thiab Candida vaginitis.

Sib tshuam nrog lwm yam tshuaj

Puas muaj ib daim ntawv teev cov tshuaj uas cov tshuaj "Fortum" tau los yog, nyob rau hauv tsis tooj, yuav siv tsis tau? Nws yuav tsum tau muab sau tseg hais tias muaj yog tsis muaj cov ntawv teev npe. Txawm li cas los, ua ntej yuav siv qhov cuab tam, nws yog yuav tsum tau nyeem cov lus qhia, tab sis, theej los ntawm "Drug kev sib tshuam". Los ntawm nws koj yuav nrhiav tau hais tias cov simultaneous siv ceftazidime nyob rau hauv siab ntau npaum li cas nephrotoxic tshuaj tej zaum yuav muaj kev tsis zoo nyob rau hauv ob lub raum.

Diuretics, vancomycin, aminoglycosides thiab clindamycin significantly txo clearance ntawm lub active tshuaj ntawm cov tshuaj, uas ua nyob rau hauv kev raug mob ntawm nephrotoxic los.

Bacteriostatic tshuaj tua kab mob, xws li tshuaj "chloramphenicol" txo cov nyhuv ntawm beta-lactam tshuaj tua kab mob.

Medicament "Fortum" yog tsis tau tshaj zoo tag nrho cov kev daws tso dej raws leeg thawj coj. Txawm hais tias nws yuav tsum tau muab sau tseg hais tias ceftazidime yog tsis ruaj khov nyob rau hauv ib tug tov ntawm sodium bicarbonate. Nyob rau hauv no kev twb kev txuas, cov tshuaj yeeb dej caw yog txwv tsis pub raws li ib tug hnyav.

Qhia rau kev siv ntawm cov tshuaj

Yuav ua li cas koj yuav tsum paub ua ntej yuav siv lub "Fortum" tshuaj? Cov nyhuv ntawm tshuaj tua kab mob tej zaum yuav detrimental rau lub thaj ntawm cov neeg mob. Yog hais tias cov neeg mob nyob tsis haum cov tshuaj tiv thaiv, cov tshuaj yuav tsum tau abolished.

Heev siv ntawm no medicament yuav ua rau kom muaj zog loj hlob ntawm cov kab mob loog. Nyob rau hauv cov ntaub ntawv no, tej zaum nws yuav yuav tsum tau discontinuation ntawm txoj kev kho.

Tshuaj "Fortum": counterparts thiab nqi

Hu ua pheej yig tshuaj no yog xam tias yog heev yooj yim. Yog li ntawd ntau npaum li cas cov tshuaj "Fortum"? Nws nqi tej zaum yuav txawv thiab nyob ntawm seb ntau npaum cov tshuaj. Raj mis 500 ml Koj yuav yuav 196 Lavxias teb sab rubles thiab 1 g thiab 3 g - 452 thiab 626 rubles feem.

Xav txog daim ntawv teev cov tshuaj uas nws txiav txim yog zoo li cov tshuaj "Fortum":

• "Vitsef";
• "Bestum";
• "Kefadim";
• "Kefadim";
• "Orzid";
• "Lorazidim";
• "Tizim";
• "Fortazim";
• "Tazitsef";
• "Ceftazidime";
• "Tsefzid";
• "Tseftidin".

Xyuas ntawm cov tshuaj

Yuav ua li cas cov neeg mob hais txog cov tshuaj "Fortum"? Lawv cov nqi yog heev txaus siab. Ntxiv mus, feem ntau cov neeg mob lub xeev uas suav tias yog qhov tshuaj tua kab mob no zoo heev. Txawm hais tias muaj yog ib pab pawg ntawm cov neeg mob mus rau leej twg nws yog tsis haum vim coob tus mob tshwm sim.