"Domidon": cov lus qhia rau kev siv, thiab dab tsi yog nws rau

Nrog haumxeeb mob ntawm lub digestive ib ntsuj av tau ntsib txhua leej txhua tus. Feem ntau cov feem ntau, tsis xis nyob rau hauv lub epigastric cheeb tsam tshwm sim vim hais tias ntawm cov neeg pluag thiab kev noj haus. Yuav kom txhim kho kev zom thiab leeb pais plab muab nchuav, gastroenterologists xav noj tshwj xeeb txhais tau tias. Ib tug ntawm lawv xa tshuaj "Domidon". Cov lus qhia rau kev siv, tawm tswv yim thiab indications ntawm cov tshuaj no yog hais hauv qab no.

Form, muaj pes tsawg leeg, tshuaj ntim

Medicament "Domidon" kev qhia yog muab cia rau hauv lub ntim ua los ntawm cov duab los qhia, ua nyob rau hauv cov ntsiav tshuaj daim ntawv. Lawv muaj domperidone, raws li zoo raws li cov khoom xyaw xws li lactose monohydrate, povidone, maize starch, microcrystalline cellulose, titanium dioxide, pre-gelatinized starch, magnesium stearate, sodium lauryl sulfate, polyethylene glycol 4000, hydroxypropyl methylcellulose los yog sepifilm 752 Blanc.

Nyob rau hauv lub qhov muag ntawm lub tsev no mus txog rau lub contour hlwb.

pharmacology

Yuav ua li cas yog cov tshuaj raws li "Domidon" (ntsiav tshuaj)? Cov lus qhia rau Siv hais tias nws yog ib hom GI kom. Nws paus ntsiab lus ntawm lub lag luam yog piav los ntawm tus muaj peev xwm los thaiv lub D2-dopamine receptors. Raws li ib tug tshwm sim ntawm cov nyhuv zuj zus qhov ntev ntawm lub peristaltic taw nyob rau hauv lub 12-tiperstnoj hnyuv thiab pais plab antral cheeb tsam. Tsis tas li ntawd accelerates tus muab nchuav ntawm hais tias nruab nrog cev thiab tsub kom lub suab nrov ntawm cov hlab pas (tsawg dua sphincter).

Cov tshuaj no muaj tsis ntxim rau pais plab tso pa tawm. Nws anti-emetic nyhuv vim muaj ib tug ua ke gastrokinetic nyhuv, thiab kev thaiv kev ntawm dopamine receptors nyob rau hauv lub chemoreceptor txhais cheeb tsam, uas yog nyob sab nraum cov ntshav-hlwb barrier. Nyob rau hauv tas li ntawd, cov tshuaj no eliminates nros thiab xeev siab.

kev tig tau yam ntxwv

Yuav ua li cas yog cov yam ntxwv ntawm cov kinetics ntawm cov tshuaj "Domidon"? Cov lus qhia rau kev siv qhia tias qhov cuab tam sai sai thiab tag nrho absorbed los ntawm cov hnyuv. Nws yog metabolized nyob rau hauv daim siab thiab mob huam phab ntsa, uas muaj ib tug tsis tshua muaj bioavailability (nyob ib ncig ntawm 15%).

Txo pais plab acidity kua txiv thiab noj ho qeeb thiab txo qhov haum ntawm domperidone. Nws ncov ntshav concentration tiav ib teev tom qab haus.

Kev sib txuas lus ntawm cov tshuaj rau ntshav cov nqaijrog yog kwv yees li 91-94%. Nws yog tsis zoo penetrates los ntawm lub BBB, tab sis tsis zoo nyob rau hauv leej niam lub mis nyuj (qib yog hais txog 1/4 ntawm tag nrho cov concentration hauv cov ntshav).

Lub lom transformation ntawm cov kev npaj yog nqa tawm los ntawm N-dealkylation thiab hydroxylation.

Lub ib nrab-lub neej sij hawm ntawm cov tshuaj yog 7-10 teev. Nyob rau hauv lub raum tsis ua hauj lwm (mob loj heev), qhov no daim duab yog ua.

Muab tshuaj los ntawm lub cev nrog rau cov quav thiab zis.

Indications rau kev txais neeg kawm

Nyob rau hauv tej rooj plaub, cov neeg laus teev "Domidon" ntsiav tshuaj? Kev siv cov tshuaj no muaj nyob rau hauv ntuav thiab xeev siab raws li mob nyob rau hauv lub plab, cov kev xav ntawm fullness thiab kub siab.

Raws li rau cov me nyuam, lawv pom zoo kom hais tias lub tsev no tsuas yog rau cov xeev siab thiab ntuav.

Contraindications

Thaum tsis siv cov tshuaj "Domidon" (cov lus qhia rau kev siv thiab rau nws yog dab tsi - nws yuav tag nrho yuav raug hais nyob rau hauv no tsab xov xwm)? Contraindications ntawm qhov cuab tam yog:

• hnyuv los ntshav;
• npau taws me ntsis;
• perforation ntawm txoj hnyuv / plab ;
• txhua yam plab hnyuv rhuav txhua;
• hypophysis mob (prolactin-secreting);
• nrog qhov ncauj ntaub ntawv "Erythromycin", "ketoconazole" los yog lwm yam inhibitors ntawm CYP 3A4, raws li zoo raws li cov neeg ua hauj uas lengthen lub luv Q-T.

Tshuaj "Domidon": cov lus qhia rau kev siv

Xam tias yog yus kev noj tshuaj yuav tsum tsuas yog noj hauv tsev ua ntej ib tug noj mov. Thaum tau txais cov tshuaj noj tom qab ib tug noj mov ntawm lawv haum yog dog dig qeeb qeeb.

Cov me nyuam los ntawm 12 xyoo thiab cov laus, cov tshuaj no yog tshuaj 10-20 mg peb zaug ib hnub twg. Qhov siab tshaj plaws txhua txhua hnub koob tshuaj tshuaj yog 80 mg.

Lub caij ntawm thawj txoj kev kho - 4 lub lis piam. Yog hais tias tsim nyog, ntxiv siv ntawm cov tshuaj yuav tsum tau sab laj nrog koj tus kws kho mob.

Nrog rau txoj kev loj hlob ntawm lub raum tsis ua hauj lwm yuav tsum txo lub multiplicity ntawm cov tshuaj. Nrog kev xav txog rau lub siab tsis ua hauj lwm, nyob rau hauv cov ntaub ntawv no, nws tsis yog sau rau koj.

phiv

Puas muaj cov tsos ntawm cov nyom tshua tshuaj "Domidon"? Cov lus qhia rau kev siv qhia hais tias xws li phiv los tsis tshwm sim:

• ib qho kev nce nyob rau hauv prolactin theem;
• anaphylaxis ;
• nervousness, ntxhov siab;
• edema, lengthening lub luv Q-T, palpitations, dysrhythmia thiab lub plawv dhia;
• qhov ncauj qhuav, extrapyramidal teeb meem, mob taub hau, nqhis dej, insomnia, txob taus, kiv taub hau, nkees nkees, nkees, convulsions;
• gastrointestinal mob;
• gynecomastia, galactorrhea, amenorrhea;
• khaus, dysuria;
• nquag tso zis, daim tawv nqaij ua pob liab vog;
• stomatitis, conjunctivitis;
• asthenia, mob nyob rau hauv ob txhais ceg;
• nce nyob rau AST, ALT thiab roj uas txhaws taus.

tej tswv yim pom zoo

Yuav ua li cas yuav tsum tau qhia tus neeg mob, ua ntej koj muab ib tug yeeb tshuaj "Domidon"? Cov lus qhia rau Siv hais tias qhov cuab tam yuav tsis tau ua ke nrog antisecretory thiab antacid tshuaj.

Rau cov kev kho mob ntawm cov me nyuam nyob rau hauv 12 lub xyoos ntawm hnub nyoog nrog ib tug lub cev hnyav tsawg tshaj li 35 kg siv cov tshuaj no yuav tsum tsis txhob yuav.

Thaum lub sij hawm txoj kev kho nrog cov tshuaj no yuav tsum caiv txhob kev tswj thiab ua hauj lwm nrog yus machinery.

neeg xyuas

Tam sim no uas koj paub tias dab tsi nta yog cov yam ntxwv ntawm cov tshuaj "Domidon". Cov lus qhia rau kev siv thiab rau dab tsi nws yog, peb tau hais rau saum toj no.

Feem ntau cov neeg muas zaub uas siv cov chaw qhia hais tias nws zoo eliminates kub siab, nros thiab xeev siab. Tsis tas li ntawd, cov tshuaj txhawb rau sai muab nchuav ntawm lub plab, kom txhob muaj cov kev xav ntawm heaviness thiab tsis xis nyob rau ib yam tsawg kawg nkaus.

Lub tsuas disadvantage ntawm cov tshuaj no yog cov loj xov tooj ntawm cov kev phiv.