"Cefixime" (ncua kev kawm ntawv): kev qhia rau cov me nyuam, hauj lwm, muaj pes tsawg leeg thiab xyuas

"Cefixime" - ncua kev kawm ntawv (qhia rau cov me nyuam los txog rau cov txhais tau tias), lub active khoom sib ua zaub mov uas yog ib tug cephalosporin peb tiam. Qhov no tshuaj tua kab mob zoo kho tsis tau tsuas yog cov kab mob ntawm lub pa system, tab sis tseem muaj lwm yam kab mob. Cov tshuaj no kuj muaj nyob rau hauv cov tshuaj ntsiav daim ntawv.

Qauv thiab pes tsawg leeg

"Cefixime" (neeg siv, daim ntawv thov thiab muaj pes tsawg leeg ntawm no formulation qhia nws zoo tej yam nyob rau hauv tus me nyuam lub cev thaum txias, SARS, mob caj pas, mob khaub thuas, thiab hais txog. D.) Lub active ingredient comprises cefixime trihydrate. Nyob rau hauv 5 ml ntawm cov raug muab tshem tawm tau 100 mg ntawm active ingredient. Ntxiv cov khoom xyaw yog sodium croscarmellose, sodium carboxymethyl cellulose, xanthan cov pos hniav, microcrystalline cellulose, sodium benzoate, citric acid monohydrate, tsw, sucrose.

Koom Haum tsiav tshuaj ua magnesium stearate, sodium sulfate lauryl, zaub roj, hydrogenated, croscarmellose sodium, microcrystalline cellulose.

Ncauj ncua kev kawm ntawv yog nyob rau hauv ib ntau npaum ntawm 100 mg / 5 ml nyob rau hauv vial 30 ml thiab 100 mg / 5 ml nyob rau hauv ib tug minyuam lam fwj tshuaj ntawm 60 ml. Lub tsiav tshuaj muaj 200 thiab 400 mg ntawm active tshuaj.

Npaj ib ncua kev kawm ntawv yuav tsum tau muab cia rau hauv ib qhov chaw txias tsis ntau tshaj li kaum plaub hnub. Ib tug npaj nyob rau hauv daim ntawv ntawm cov tshuaj tau muab cia rau hauv ib tug kub tsis siab tshaj +25 ° C. Txee lub neej ntawm undiluted ncua thiab tsiav tshuaj - txog peb lub xyoos.

pharmacology medicament

"Cefixime" - ncua kev kawm ntawv (qhia rau cov me nyuam tag nrho qhia txog cov kev siv ntawm cov tshuaj), uas muaj ib tug high stability rau lub xub ntiag ntawm beta-lactamases - enzymes, uas yog aimed ntawm combating beta-lactam tshuaj tua kab mob. Raws li ib tug tshwm sim, resistant rau penicillins thiab cephalosporins kab mob tej zaum yuav raug rau cov teebmeem ntawm lub active tshuaj ntawm cov kev npaj.

"Cefixime" yog ib tug broad-spectrum tshuaj tua kab mob thiab muaj feem xyuam rau feem ntau ntawm cov kab mob los ntawm kab mob, cov uas yog:

• Gram-zoo - yog tus kab mob Streptococcus pneumoniae, pyogenes, tus kab mob Streptococcus.
• Gram xws li Proteus Mirabilis, Haemophilus kab mob, Moraxella (Branhamella) catarrhalis, Escherichia coli, gonococcus.

"Cefixime" instantly absorbed nyob rau hauv txoj hnyuv ib ntsuj av. Tus nqi ntawm tus txheej txheem no tsis cuam tshuam rau cov zaub mov kom tsawg. Bioavailability rau cov neeg laus thiab cov me nyuam - txog 30-50%. Qhov siab tshaj plaws concentration ntawm active ingredient yog tiav tom qab 2-6 xuab moos tom qab haus ntawm cov tshuaj, tsis hais txog ntawm nws tso tawm cov ntaub ntawv. Hais txog ib nrab ntawm cov koob tshuaj rau lub hnub yog tas nyob hauv cov zis nyob rau hauv unchanged daim ntawv. Ib feem ntawm cefixime trihydrate mus nrog bile.

Muaj mob loj tsawv raum tsis ua haujlwm 50% ntawm cov active tshuaj los ntawm tib neeg lub cev mus txog 6.4 teev. Rau hauv loj heev raum tsis ua hauj lwm rau ib nrab-lub neej ntawm 11.5 teev.

indications

"Cefixime" - ncua kev kawm ntawv (qhia rau cov me nyuam yog tsis pom zoo kom siv nws tsis muaj kev noj kev haus ib tug kws kho mob), uas yog feem ntau kws kho rau ntau yam kab mob kab mob ntawm lub mob txeeb zig. Qhov kev siv yog ib daim ntawv ntawm mob plab hnyuv kab mob. Nws prescribes ib tug tshuaj tua kab mob los kho ib tug xov tooj ntawm cov kab mob tshwm sim los ntawm tus kab mob Streptococcus pneumoniae thiab tus kab mob Streptococcus pyogenes. Thov cov tshuaj ENT-cov kab mob, xws li pharyngitis, tonsillitis, otitis media thiab sinusitis. Nws yog siv nyob rau hauv ntau yam ntaub ntawv ntawm bronchitis, mob ntsws thiab lwm yam mob ua pa kab mob.

Contraindications

Kiag txhob nyob rau hauv cov neeg uas muaj kev tsis haum rau tshuaj tua kab mob cephalosporin, tshuaj "cefixime" (ncua kev kawm ntawv). Cov lus qhia rau cov me nyuam (xyuas ib co poj niam hais tias cov kev txhim kho tom qab noj cov tshuaj los rau cov 2-3rd hnub ntawm txoj kev siv) mus rau kaum ob xyoos txwv tsis pub siv yeeb tshuaj nyob rau hauv tsiav tshuaj. Rau cov kev kho mob ntawm cov me nyuam los ntawm rau lub hlis mus rau kaum ob lub xyoos yuav tsum tau ua ntawv thov ncua kev kawm ntawv. Tsis txhob noj cov tshuaj rau cev xeeb tub thiab niam pub mis niam tshwj tsis yog tias cov kev tsim zoo ntxim rau leej niam ob peb lub sij hawm tshaj qhov uas yuav ntawm me nyuam hauv plab abnormality, ces tus kws kho mob tso cai rau kev siv.

"Cefixime": cov lus qhia rau kev siv rau cov me nyuam

Lub ncua kev kawm ntawv, tsis zoo li yus kev noj tshuaj, tso cai rau siv rau cov me nyuam yaus. Qaug dej qaug cawv tom qab kaum tsib feeb tom qab noj mov.

Rau cov me nyuam muaj hnub nyoog ntawm kaum ob xyoos thiab lub siab tshaj plaws neeg laus hnub kom tsawg ntawm cov tshuaj yog 400 mg. Duration ntawm lwm yam uas kws kho mob. Qhov no lub sij hawm nyob rau hauv lub hnub nyoog thiab tus kab mob heev. Cov neeg mob uas creatinine clearance, sib npaug zos rau 21 thiab 60 ml / min, tus nqi ntawm tau yog txo mus rau 300 mg ib hnub twg. Nyob rau hauv cov neeg mob uas muaj ib tug creatinine clearance tsawg tshaj li 20 mL / feeb koob tshuaj txo kom 200 mg ib hnub twg.

Cov me nyuam los ntawm rau lub hlis mus rau kaum ob lub xyoos muab lwm daim ntawv ntawm cov tshuaj "cefixime" - ncua kev kawm ntawv. Instruction rau cov me nyuam, yuav ua li cas yug lawv tus kheej hmoov, hais txog zaj uas. Ua li no, siv sij hawm 30-35 ml ntawm dej tsis qis tshaj li +25 ° C thiab ncuav lub kua rau hauv lub minyuam lam fwj tshuaj nrog rau cov hmoov, kaw thiab huv si shaken tag nrho cov txheem. Tom qab no tus txheej txheem, lub minyuam lam fwj tshuaj yog qhib thiab ntxiv cov dej yog ntxiv rau kev txaus ntshai. Tom qab uas lub hau yog cov dua, thiab lub Cheebtsam yog kom huv si tov.

Haus "cefixime" yuav ua tau ob qho tib si ua ntej noj mov thiab tom qab. Yog hais tias lub tshuaj tua kab mob tau tshwm sim los voos ntawm tus mob huam, nws yog siv thaum lub sij hawm noj mov.

Cov koob ntawm cov raug muab tshem tawm yog txiav txim raws li cov hnub nyoog thiab nyhav rau tus me nyuam. Piv txwv li, cov me nyuam los ntawm rau lub hlis mus rau kaum ob lub xyoos ntawm hnub nyoog yuav tsum tau mus coj 8 mg ib kilogram ntawm lub cev hnyav. Cov pom zoo npaum li cas yuav tsum tau muab faib mus rau hauv ob peb ua sawv, los yog tag nrho ntawm koj muaj peev xwm haus dej haus ntawm ib lub sij hawm.

Cov me nyuam mos kaum ob xyoos muaj lub cev hnyav ntawm 50 kg los yog ntau tshaj, tshuaj laus ntau npaum uas yuav ncav cuag 400 mg ib hnub twg. Hoob no ntawm kev kho mob yog txiav txim los ntawm lub chav kawm ntawm tus kab mob no.

Sab los "cefixime" tshuaj

Instruction (khoom piav qhia ceeb toom txog qhov tseem ceeb ntawm kev ua raws cai nrog tag nrho cov tswv yim pom zoo) hais tias cov tshuaj yuav ua rau ib tug xov tooj ntawm cov kev phiv, no muaj xws li:

• raws plab, xeev siab thiab mob nyob rau hauv lub plab cheeb tsam;
• indigestion, plab thiab flatulence;
• ntau yam daim tawv nqaij sawv pob (pob, pruritus, thiab urticaria);
• malfunction ntawm lub lymphatic system;
• kev tsis haum tshuaj thiab ntshiab kev mob kev nkeeg;
• qhov ncauj qhuav, thiab cov tuam tsis muaj zog;
• raum tau hauj lwm;
• fungal kab mob ntawm cov poj niam qhov chaw mos mutilation;
• kiv taub hau, qaug zog, thiab mob taub hau;
• tawm fws, alopecia thiab epidermal necrolysis (kev tuag ntawm sab sauv txheej ntawm daim tawv nqaij).

Nyob rau hauv tej rooj plaub, muaj ib tug overdose, uas manifests nws tus kheej nyob rau hauv daim ntawv ntawm kev zawv plab, kiv taub hau, xeev siab thiab ntuav. Thaum nrhiav kom tau ntawm tej tsos mob yuav tsum tau pais plab lavage, coj antihistamines ua pa txoj kev kho.

Sib tshuam nrog lwm yam tshuaj

Nephrotoxicity ntawm cov tshuaj zoo tshaj yog tias koj noj nws nyob rau tib lub sij hawm "Furosemide" thiab aminoglycosides.

Duration prothrombin lub sij hawm nrog los ntshav ces los yog tsis muaj qab thaum uas siv cov "cefixime" nrog anticoagulants.

Thaum lub sij hawm kho kho yuav tsum tau txwv tsis pub haus dej haus cawv thiab tonics.

analogs medicament

Pheej muaj pov thawj nws cov hauj lwm zoo nyob rau hauv sib ntaus tawm tsam kis kab mob "cefixime" (ncua kev kawm ntawv rau cov me nyuam). Cov lus qhia (nqi ntawm cov tshuaj no yog haum siab) piav txog nyob rau hauv kom meej tag nrho cov txoj kev kho mob, raws li tau zoo raws li indications thiab contraindications. Yog hais tias qhov cuab tam yog tsis haum, koj yeej ib txwm nrhiav ib tug haum analogue. Raws li cov ntsiab lus ntawm cov active tshuaj thiab hauv daim ntawv ntawm cov tshuaj yog zoo li xws tshuaj:

• "Ikzyme";
• "Lopraks";
• "Cefixime".

Qhov saum toj no cov khoom muaj nyob rau hauv daim ntawv ntawm cov hmoov rau ncua kev kawm ntawv thiab haum rau cov me nyuam. Los ntawm capsular analogs muaj xws li "Supraks Komfortab", "Supraks Soljutab", "Lopraks" thiab "Flamifiks".

Cov nyiaj no rau nws cov teebmeem rau lub cev muaj peev xwm kiag li hloov lub "cefixime" (ncua kev kawm ntawv rau cov me nyuam). Cov lus qhia (nqi tej zaum yuav txawv me ntsis nyob rau hauv lub margins nyob rau hauv lub khw muag khoom network) ceeb toom tias ua ntej yuav siv no tshuaj tua kab mob yuav tsum tau nrog ib tug kws kho mob.

Tus nqi ntawm cov tshuaj

Qhov no yog ib cov tshuaj tshiab uas tau tau chaw ntev los no. Dua li no, koj yuav nrhiav tau nws nyob rau hauv txhua txhua lub khw muag tshuaj. Tus nqi ntawm cov nyiaj yog nyob ib ncig ntawm 900 rubles. Tej zaum yuav txawv me ntsis nyob rau hauv cov kev taw qhia ntawm zuj zus lawm los yog ua tus nqi ntawm cov tshuaj "cefixime". Cov lus qhia rau kev siv, hauj lwm, xyuas niam tham txog cov hauj lwm zoo ntawm no lub cuab tam nyob rau hauv kev kho mob qa thiab lwm yam kev mob, yog li cov tshuaj yog tsim nyog cov nyiaj.

Xyuas ntawm kev npaj

"Cefixime" - ncua kev kawm ntawv (qhia rau cov me nyuam ceeb toom hais tias ua ntej tau txais cov tshuaj yuav tsum paub txog contraindications), uas muaj ib tug ntau ntawm cov zoo tswvyim. Cov poj niam hais tias cov tshuaj lub hauj lwm zoo. Nws yog hais tias cov kev txhim kho nyob rau hauv lub zwj ceeb ntawm tus me nyuam tuaj rau lub thib ob hnub ntawm nws kev txais neeg kawm. Nws nres mob caj pas, hnoos zoo, dhau nkees thiab lwm yam tsos mob ntawm tus mob khaub thuas. Lawv cam tias lub chaw muaj ib tug broad spectrum ntawm kev ua si thiab li yuav pab kho ib tug mob caj pas, tracheitis thiab kab plab hnyuv kab mob. Pheej muaj pov thawj yuav tsum tau zoo tshuaj nyob rau hauv kev kho cov kab mob ntawm lub Upper pa ib ntsuj av tau, uas ua sai sai thiab nraaj. Zoo li cov me nyuam, vim hais tias nws muaj ib tug kaj thiab ilv tsw ntawm cov txiv pos nphuab.

Ntawm cov drawbacks ntawm medicament kev cais tsis haum cov tshuaj tiv thaiv, nqi thiab sij hawm luv luv cia ntawm reconstituted ncua kev kawm ntawv. Cov poj niam hais tias rau cov me nyuam hnub nyoog 10-12 xyoo yuav tau mus yuav ob fwj, vim hais tias ib tug yog tsis txaus rau ib tug tag nrho cov hoob kawm ntawm kev kho mob. Ib tug tej yam yog ib feem ntawm cov neeg tsis pom muaj cov nyhuv tom qab qhov kev siv ntawm cov tshuaj no thiab xav noj nws puas.

xaus

"Cefixime" - yog ib tug antimicrobial neeg sawv cev, sai tom qab mob ntsws thiab lwm yam kab mob kab mob. Feem ntau yeej tsis ua phiv los. Nws sawv tawm rau nws cov efficiency.