Amlodipine qhia

Tshuaj "Amlodipine" tej zaum paub rau ntau thawj-tes. Yeej, cov tshuaj no yog tshuaj rau cov neeg mob angina. Cia peb xav txog cov tshuaj "Amlodipine" uas nws cov lus qhia muaj cov nram qab no ntaub ntawv.

Muaj pes tsawg leeg. Ib tug ntsiav tshuaj (5 mg) muaj cov active tshuaj amlodipine besylate. Raws li cam siv lactose, qos starch, collidone, microcrystalline cellulose, magnesium stearate.

General hauj lwm. "Amlodipine" Ntsiav tshuaj dawb los yog ze li ntawm dawb nrog ob mog ob leeg. Qee zaus lub teeb yuav tsum tam sim no marbling.

Pharmacodynamics. Dihydropyridine derivative - blocks calcium "qeeb" thib ob-tiam raws muaj gipotezivnoe thiab antianginal los. Txuam nrog lub dihydropyridine receptor thiab yog cov blockade ntawm calcium raws, li no kom txhob muaj cov transmembrane tso cai ntawm lub calcium ions rau hauv lub cell (mus rau ib tug ntau dua raws li nyob rau hauv tus nqaij ntawm ntsha tshaj nyob rau hauv mob myocytes). Antianginal cov nyhuv yog tshwm sim los ntawm expansion ntawm cov hlab ntsha thiab arterioles nyob rau hauv lub periphery: angina umenshaetsnizhaet heev ntawm myocardial ischemia, peripheral leeg expands, li no kom txhob muaj tag nrho cov vascular peripheral kuj, nyob rau hauv tas li ntawd yuav pab kom txo tau cov preload rau hauv lub plawv, thiaj li qhov yuav tsum tau lub plawv ntawm oxygen. Nyob rau hauv cov neeg mob uas angina, lub hnub ib koob tshuaj tsub kom tus mus dhia lub sij hawm fiznagruzki, slows txoj kev loj hlob ntawm ischemia thiab angina, ntxiv rau txhua yam thiaj li multiplicity ntawm angina tawm tsam thiab kev xav tau kev nitroglycerin. Yog li, cov neeg mob nrog angina xav tau kev pab "Amlodipine" phau ntawv no ua pov thawj.

Tshuaj. Tom qab qhov ncauj thawj coj ntawm cov tshuaj yog maj mam yaim los ntawm lub hnyuv ib ntsuj av. Tsis nruab nrab bioavailability yog 64%, cov feem ntau concentrated nyob rau hauv cov ntshav ntshiab tom qab 6-9 teev. Ruaj tshuav nyiaj li cas nyob rau hauv cov ntshav yog pom nyob rau hauv 7 hnub. Khoom noj khoom haus tsis cuam tshuam rau haum ntawm amlodipine. Nyob rau hauv cov neeg laus cov neeg mob (laus tshaj 65 xyoo) lub feem ntawm cov tshuaj yog qeeb piv rau cov hluas, tiam sis qhov no sib txawv yog tsis clinically tseem ceeb.

"Amlodipine" qhia uas muaj tag nrho cov ntaub ntawv tsim nyog muaj cov nram qab indications rau daim ntawv thov: lub arterial tawg (ua ke nrog lwm yam los yog zoo ib yam li txhais tau tias monotherapy), exertional angina, vasospastic angina (Prinzmetal lub angina).

Contraindications.

- siab rhiab heev rau lub active ingredient thiab lwm yam dihydropyridine derivatives;

- hypotension nyob rau hauv kev mob loj daim ntawv;

- cardiogenic poob siab, cev qhuav dej;

- tsis ruaj tsis khov angina (tsuas yog - Prinzmetal angina);

- lactation thiab cev xeeb tub;

- rau cov neeg nyob rau hauv 18 lub xyoos ntawm kev ruaj ntseg thiab cov nyhuv tsis tau tsim muaj.

Cov tshuaj thiab txoj kev ntawm daim ntawv thov. Siv "Amlodipine" qhia muaj raws li nram no: sab hauv, qhov tsawg kawg nkaus koob tshuaj 5 mg, lub siab tshaj plaws - 10 mg 1 lub sij hawm ib hnub twg. Thaum tawg koob tshuaj rau txij nkawm yuav tsum muaj 5 mg ib hnub twg. Thaum tus cwj nrag coj ib zaug 5-10 mg ib hnub twg. Nyias cov neeg mob, raws li tau zoo raws li uas tsis muaj cov neeg mob thiab cov neeg mob impaired siab ua tau hauj lwm muab 2.5 mg.

Tshwj xeeb cov lus qhia. Thaum lub sij hawm hauv chav kawm ntawm kev kho mob nrog "Amlodipine" yuav tsum ua raws li qhov nyhav thiab noj ntawm tej yam raws li sodium, tej zaum yuav tsum tau ib tug tshwj xeeb cov khoom noj. Nws yog ib qho tseem ceeb ua raws li cov qhov ncauj thiab cov hniav, mus saib tus kws kho hniav tsis tu ncua (kom tsis txhob mob thiab los ntshav cov pos hniav). Los ntawm nce lub koob tshuaj nyob rau hauv cov neeg laus yuav tsum tau ceev faj saib xyuas. Cov nyhuv ntawm cov tshuaj nyob rau hauv lub peev xwm tsav ib lub tsheb muaj yog tsis muaj ntaub ntawv. Txawm li cas los, nws yuav tsum tau borne nyob rau hauv lub siab hais tias nyob rau hauv ib co neeg nws muaj peev xwm ua rau me ntsis kiv taub hau thiab nkees nkees.