Noj qab haus huv, Npaj
Naiz (ntsiav tshuaj) - phau ntawv qhia.
ntau npaum daim ntawv
Cov kev npaj no yog ua nyob rau hauv 3-tshuaj ntaub ntawv - raug tshem tawm, dispersible ntsiav tshuaj thiab cov pa. Lub ncua kev kawm ntawv yog ib tug tsis hnov tsw qab ntxiag nrog ib tug hint ntawm daj nyob rau hauv cov xim thiab cov heev yam ntxwv saj ntawm cov tshuaj no. Lub ncua kev kawm ntawv muaj peev xwm yuav redispersed los ntawm kev tuav lub minyuam lam fwj.
Ntsiav tshuaj yog manufactured yuav luag dawb, nrog rau ib tug me ntsis yellowish tinge. Ntsiav tshuaj ntawm yeej zoo lawm, biconcave, nws ob chaw yog tus.
Nise muaj pes tsawg leeg:
ncua kev kawm ntawv
active tshuaj
- Nimesulide - 50 mg (5 ml ntawm kev ncua)
cam:
- sorbitol
- piam thaj
- xanthan cov pos hniav
- propyl
- methylparaben
- citric acid
- txiv puv luj tsw
- Daj zas WS
- glycerol
- polysorbate
- purified dej
dispersible ntsiav tshuaj
active tshuaj
- Nimesulide - 50 mg (Rooj 1).
cam
- aspartame
- calcium phosphate
- microcrystalline cellulose
- carboxymethyl cov hmoov txhuv nplej
- pob kws cov hmoov txhuv nplej
- talc
- magnesium stearate
- Colloidal silicon dioxide
- txiv puv luj tsw
ntsiav tshuaj
active tshuaj
- Nimesulide - 100 mg (Rooj 1).
cam:
- magnesium stearate
- Calcium Hydrogen Phosphate
- microcrystalline cellulose
- Anhydrous colloidal silicon
- pob kws cov hmoov txhuv nplej
- Sodium cov hmoov txhuv nplej glycolate
- purified talc
Lub pharmacological kev txiav txim ntawm cov tshuaj
Pharmacological txiav txim txog feem rau Nise - tshuaj, cov kev qhia ntawv muaj cov ntaub ntawv rau tag nrho cov ntau npaum cov ntaub ntawv. Cov tshuaj yog ib tug NSAID, muaj nyob rau hauv nws cov qauv sulfonilidnuyu grouping. Nimesulide tej zaum koom inhibitors ntawm COX-2, yog li ntawd nws muaj anti-inflammatory thiab analgesic los, nyob rau hauv tas li ntawd, cov tshuaj niamntiav analgesic los, tab sis rau ib tug tsawg degree.
Lub mechanism ntawm qhov kev txiav txim ntawm cov tshuaj txuam nrog cov hluav ntawm lub synthesis ntawm prostaglandins nyob rau hauv o thiab tsuj ntawm lub tsim ntawm cov pa radicals thiab cov inhibition ntawm myeloperoxidase tso tawm.
tshuaj
Nise txig absorbed los ntawm tus mob huam, xeeb nws siab tshaj plaws nyob rau hauv cov ntshav twb tom qab 2 teev. Cov tshuaj yog 99% protein txhua yam.
Kev npaj nize - ntsiav tshuaj daim ntawv qhia uas yog coj los ntawm official qhov chaw, metabiliziruetsya nyob rau hauv daim siab thiab tas nyob hauv cov zis, nrog 98% ntawm cov tshuaj tau txais yog tso zis thaum lub sij hawm ib hnub.
zaj lus tim khawv
- Rheumatic kab mob uas tsim sab nraum lub ob leeg capsule
- osteoarthritis
- O thiab kev mob tom qab phais
- Mob tshwm sim los ntawm dysmenorrhea
- Kub taub hau thiab mob thaum lub sij hawm mob o nyob rau hauv lub qaum tej hlab cua txhob
Sab los Nise
Ntsiav tshuaj, cov kev qhia ntawv uas tam sim no yog, muaj peev xwm tsim sab-los nyob rau hauv ntau yam systems thiab kabmob:
Tshwm sim los ntawm cov tshuaj, uas muaj feem rau hauv cov hnyuv
- xeev siab
- kub siab
- mob plab
- tarry quav
Tshwm sim los ntawm cov tshuaj, uas muaj feem rau lub hauv paus poob siab system:
- mob taub hau
- nkees nkees
- kiv taub hau
Tshwm sim los ntawm cov tshuaj, uas muaj feem rau kev tsis haum tshuaj:
- erythema
- tawm pob
- urticaria
Lwm yam kev phiv:
- Cia nyob rau hauv lub cev tawm dej
- oliguria
- o
Nise contraindications
Yog ib daim ntawv teev contraindications nyob rau hauv uas nws yog pom zoo kom tsis txhob noj cov tshuaj, thiab thaum tsim nyog kiag li, tsuas yog tom qab kev noj kev haus koj tus kws kho mob.
- Ntshav los ntawm tus mob huam
- raum tsis ua hauj lwm
- hepatic tsis ua hauj lwm
- Cev xeeb tub thiab lactation
- Peptic hnyuv kab mob
Drug sis nize
Ntsiav tshuaj, cov lus qhia rau kev siv cov uas tsis raug nyob rau hauv tag nrho thiab kev cov ntaub ntawv rau tag nrho cov tshuaj cov kev sib tshuam tus qauv yog raws li nram no: tsis pom zoo nrog rau cov nram qab no cov neeg ua hauj - phenytoin, digoxin, tej diuretics, tshuaj lithium, anticoagulants, antihypertensive tshuaj, narcotics yuav muab, methotrexate, cyclosporin .
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