Digitalis npaj: indications thiab los nyob rau hauv mob cov kab mob

Digitalis - genus ntawm flowering nroj tsuag, uas yog siv raws li ib tug tshuaj rau mob ntawm lub plawv.

Hais txog kardiotropnyh thaj chaw ntawm no paj tau ntev tau paub. Nyob rau hauv thawj ib nrab ntawm lub XVIII xyoo pua, nws pib mus rau loj hlob nyob rau hauv Russia nyob rau hauv lub apothecary vaj, thiab txij li thaum 1775, thaum lawv tau luam tawm tej hauj lwm ntawm lub British kho mob Uayteringa, digitalis npaj tau xav coj qhov chaw nyob rau hauv txoj kev xyaum ntawm cov kev kho mob ntawm lub plawv ailments.

Lub botanical yam ntxwv ntawm digitalis

Rhode Foxglove (digitalis) - Flowering nroj tsuag yog perennial tsev neeg plantaginaceae nrog loj Inflorescences ntawm lub thimbles zoo xws li cov paj thiab ilv ntsws ntsws nplooj. Bloom nyob rau hauv nruab nrab-lub caij ntuj sov (xaus rau hli ntuj-Lub Xya hli ntuj), txiv hmab txiv ntoo - folding thawv qe-puab nrog me me xim av noob. Tag nrho cov naperstyanok piav 36 hom uas yog siv rau cov kev kho mob xwb 5: digitalis lanata (qhov tseem ceeb ntawm raw cov ntaub ntawv), ntshav, ciliated, thiab grandiflora rusty.

Chiv cov tshuaj digitalis lanata yog ib tug extract los ntawm cov nplooj ntawm tus thawj thiab thib ob xyoo. Tam sim no, pharmaceuticals digitalis glycosides tau los ntawm lub sim saum nruab ntug qhov chaw ntawm cov nroj tsuag, mowed ua ntej flowering.

Tag nrho cov tshuaj lom foxglove, qhia hais tias ib tug loj tus naj npawb ntawm biologically active tshuaj thiab yuav tsum tau ceev faj tuav.

Tshuaj Cheebtsam thiab daim ntawv thov foxglove

Cov tshuaj digitalis muaj xws li nws cov ntsiab active cov khoom xyaw - mob glycosides: digitoxin, gitoksin, digoxin, atsetildigoksin thiab ntau lwm tus neeg, raws li tau zoo raws li organic acids, saponins, flavonoids.

Feem ntau cov active Cheebtsam muaj hydrolytic theem nrab keeb kwm, i.e. tau los ntawm enzymatic cleavage ntawm molecules lawm tab glycosides.

digitalis cov tshuaj siv nyob rau hauv cov kev kho mob ntawm ntau cov kab mob plawv, mas muaj feem xyuam rau cov kev tsis taus ntawm lub plawv thiab cov hlab ntsha:

1. Lub plawv tsis ua hauj lwm thiab ntau yam organic txhab ntawm lub plawv lug (xws li raws li ib tug tiv thaiv kev ntsuas).
2. Kab mob ntawm lub plawv li qub ua rau decompensation.
3. Atrial fibrillation.
4. O thiab degeneration ntawm cov kev mob plawv.
5. Paroxysmal tachycardia nyob rau hauv cev xeeb tub cov poj niam.
6. Kev npaj rau mob phais.

Thaum ua txhaum ntawm lub mob conduction system (block) thiab bradycardia digitalis glycosides tsis muab.

Yuav ua li cas puas cov tshuaj digitalis glycosides

Cais ntawm nyom digitalis glycosides kev ntxim rau cov leeg plawv. Nyob rau hauv lub plawv tsis ua hauj lwm, cov nyhuv ntawm digitalis daim ntawv thov yog raws li nram no:

• txo nyob rau hauv lub plawv dhia;
• kom nyob rau hauv myocardial contractile quab yuam;
• lengthening lub sij hawm ntawm so lub plawv (diastole).

digitalis npaj muaj tau ntse siv nyob rau hauv cov kev kho mob ntawm lub plawv tsis ua hauj lwm, thaum lub plawv yog tsis tau tiv nrog lub nce qib ntawm cov hlab ntsha, uas yog nyuab los ntawm edema thiab trophic ntshawv siab. Nyob rau hauv cov ntaub ntawv no, los ntawm glycosidic tshuaj yuav tsum:

• nce mob tso zis (tus nqi ntawm cov ntshav los ntawm cov ventricles ib txo);
• zoo tshaj muab nchuav ntawm lub ventricles thaum lub sij hawm systole;
• txo cov ntshav ntim circulating nyob rau hauv cov hlab ntsha thiab, thiaj li, txo o;
• normalization ntawm lub plawv dhia tachycardia;
• acceleration ntawm cov ntshav khiav tsis zoo hauv lub vascular txaj;
• nce nyob rau vascular laus, uas yog nrog los ntawm ib tug me ntsis sawv nyob rau hauv cov ntshav siab.

Digitalis toxicity yuav ntxias undesirable phiv kev cuam tshuam ntawm tus mob huam, lub paj hlwb, lub plawv dhia hloov. Tsis tau tso cai siv ntawm cov tshuaj yog tsis tsim nyog, cov kev kho mob regimen tus kws kho mob xaiv xwb ib tug muab ib tug neeg mob.

Tshuaj los ntawm foxglove woolly

"Tselanid" - mob glycoside sai txiav txim yog nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj thiab cov tshuaj tso dej raws leeg txhaj tshuaj. Lub ntsiab indications - plawv tsis ua hauj lwm, tachycardia, atrial fibrillation.

"Digoxin" yog yus muaj los ntawm ib qho kev nce nyob rau hauv myocardial contractility, tsis ua txhaum lub coronary ncig thiab thiaj o vim lub diuretic los. Intravenously thiab hais lus. Nws yog qhia rau mob loj heev lub plawv mob thiab thaum lub sij hawm ib tug nres ntawm paroxysmal tachycardia nyob rau hauv ib qho xwm ceev.

Kho nyhuv nce mus txog ib tug tshaj plaws tom qab ib lub sij hawm thaum lub active tshuaj nyob rau hauv lub cev mus txog ib tug tej yam concentration. Muaj yog ib tug loj zus nyhuv (txuam nrog) vim lub fact tias digitalis npaj tshwm sim maj mam.