"Asparkam": analogues, cov lus qhia rau kev siv

Medicaments regulating metabolic dab ntawm tus kab mob, yog ib tug nyias muaj nyias ib pab pawg neeg ntawm cov tshuaj uas feem ntau siv los kho tag nrho cov hom ntawm cov kab mob. Thiab cia no kab lus tsis zoo li vague thiab meaningless, nws yeej muaj tseeb. Tej yam kab mob, tej pathological txheej txheem uas tshwm sim nyob rau hauv peb lub cev, nrog los ntawm ib tug ua txhaum ntawm metabolic dab nyob rau cellular theem. Thiab hais tias tus kho lus ntawm metabolic mob nyob rau hauv feem ntau ua rau yus rov qab. Ib tug ntawm cov tshuaj uas yog siv rau kev kho ntawm hais tias mob nyob rau hauv lub cev yog "Asparkam". Nws yog tshuaj nyob rau hauv ntau pathologies. Cia saib "Asparkam" analogues ntawm cov tshuaj uas yog siv niaj hnub no.

Pharmacological characterization ntawm "Asparkama"

Raws li twb tau hais, cov kev npaj "Asparkam" yog hais txog cov pab pawg neeg ntawm cov tshuaj rau hauv lub metabolic kev ntawm lub cev. Lub mechanism ntawm qhov kev txiav txim ntawm cov tshuaj yog raws li nyob rau hauv cov nram qab no cov ntsiab lus.

Lug paub qhov tseeb tsim nyog los tswj qhov lub intracellular ionic muaj pes tsawg leeg ntawm qhov nruab nrab. Kev mloog yog them rau cov txheej txheem ntawm cell metabolism ntawm poov tshuaj thiab magnesium ions. Vim lub peev xwm ntawm thiaj li hu ua asparginatov (ib feem ntawm cov tshuaj) mus koom nyob rau hauv intracellular ion thauj muab "Asparkama" muaj txhawb rau ib qho kev nce rau hauv lawv cov concentration thiab kev txhim kho ntawm tes metabolism.

Vim hais tias lub ntsiab lub cev yog nyias teb rau ib tug tsis txaus ntawm ions (tshwj xeeb tshaj yog poov tshuaj ions), ib lub plawv, "Asparkam" exhibits cardioprotective nyhuv los ntawm xa ib tug ion tsis txaus nyob rau hauv cardiomyocytes. Qhov no, nyob rau hauv lem qhia ib tug txo nyob rau hauv excitability thiab conduction dab, uas yog reflected nyob rau hauv lub antiarrhythmic nyhuv ntawm cov tshuaj.

Los ntawm cov cawv rau cov ntsiab lus ntawm "Asparkam" magnesium ions muaj feem xyuam rau cov cellular sodium-poov tshuaj twj tso kua mis, kom txhob muaj cov concentration ntawm sodium vnutriklutochnuyu thiab dab pab repolarization ntawm lub cell daim nyias nyias. Qhov nce nyob rau hauv daim nyias nyias tej zaum ua rau yus lub fact tias cov tsawg heev npaum li cas ntawm calcium ions nyob rau hauv lub cytoplasm yog koom nyob rau hauv cov txheej txheem ntawm cov electromechanical coupling actin thiab myosin cardiomyocytes.

Asparginat tas li ntawd, ib feem ntawm cov tshuaj, txhawb nqa kom cov metabolic dab, tsub kom tsis tsuas cov amino acid synthesis, tab sis kuj cov synthesis ntawm cov amino qab zib thiab lipids, muab kev koom tes nyob rau hauv cov kev cai ntawm intracellular metabolism. Qhov tseeb tej lub zog metabolism hauv cov ischemic heart attack myocardial ntaub so ntswg thiab qhov chaw. "Panangin" - analogue "Asparkama" - vim tib yam cov ntsiab lus ntawm poov tshuaj thiab magnesium asparginata exhibits lub tib pharmacodynamic los. Qhov tseeb txhawb tshuam zoo xws li cov heev "Pananginum" nyob rau hauv lub cardiological xyaum.

Lub pharmacokinetic yam ntxwv ntawm

Sam "Asparkam" analogues ntawm cov tshuaj yog sai thiab yuav luag tag nkag mus rau mauj ncig. Feem ntawm cov tshuaj yuav siv sij hawm qhov chaw tsuas yog los ntawm kev txhais tau tias ntawm ob lub raum. Tom qab ib tug tib koob tshuaj tshaj plaws tshuaj concentration nyob rau hauv cov hlab ntsha mus txog tsis pub dhau 1-2 teev. "Asparkam" los ntawm cov hlab ntsha ntog li ions ntawm poov tshuaj, magnesium thiab asparginatov hlwb thiab pib mus koom nyob rau hauv lawv cov metabolic dab.

indications

Ntsiav tshuaj daim ntawv "Asparkam" formulation npaj (thiab ntse siv) rau cov kev kho mob ntawm cov kab mob txuam nrog mob insufficiency. Yog li, qhia rau cov lo lus uas yuav ua tau postinfarction xeev mob tom qab cardioversions los yog nrog arrhythmia thiab myocardial conduction. "Asparkam" yog zoo nyob rau hauv cov kev kho mob ntawm lub plawv tsis ua hauj lwm nrog rau kev siv ntawm mob glycosides, raws li zoo raws li nyob rau hauv lub sijhawm ntawm overdose los yog lom saluretikami (diuretic tshuaj uas dhau li ntawm ntxiv kom cov diuresis pab txhawb kev tshem tawm ntawm ions ntawm lub cev).

Cov tshuaj daim ntawv "Asparkama" muaj tau ntse siv nyob rau hauv lub complex txoj kev kho mob plawv tsis ua hauj lwm, nrog rau cov post-myocardial infarction, mob ntawm atherosclerosis thiab conduction nyob rau hauv neej coj txoj kev kho.

Contraindications mus rau yeeb tshuaj

Vim lub fact tias "Asparkam" muaj loj nyiaj ntawm cov magnesium thiab poov tshuaj ions, nws yog txhob thaum lub sij hawm mob thiab ntev lub raum tsis ua hauj lwm, raws li zoo raws li ntau zog rhiab heev rau ib los yog ntau yam ntawm cov tshuaj.

Nyob rau hauv cardiogenic poob siab (thaum lub systolic ntshav siab poob qis hauv qab no 90 hli Hg. V.) Yog tsis pom zoo kom siv "Asparkam" analogs. Cov lus qhia rau kev siv ntawd hais tias cov tshuaj no kuj txhob nyob rau hauv Addison tus kab mob thiab tej adrenal insufficiency, nyob rau hauv tus neeg mob ntawm tus neeg mob vysokostepennoy atrioventricular thaiv thiab ib tug theem siab cov ntsiab ntawm poov tshuaj thiab magnesium ions nyob rau hauv cov ntshav ntshav.

Dosing thiab Administration

Thaum uas siv cov ntsiav tshuaj daim ntawv "Asparkam" tshuaj noj ib tug los yog ob tug cov ntsiav tshuaj tom qab noj mov peb zaug ib hnub twg. Duration ntawm kev kho mob yog txiav txim los ntawm lub mus kawm tus kws kho mob raws li cov kev soj ntsuam kev kawm ntawm tus kab mob thiab kuaj cov ntaub ntawv thiab instrumental txoj kev.

Cov tshuaj daim ntawv no yog muab tsuas tso dej raws leeg thawj coj. Tus txheem ntawm ib vial yuav tsum tau yaj nyob rau hauv 50 los yog 100 ml muaj menyuam tsis taus isotonic zib tov, muab intravenously maj mam. Ua thawj coj yuav tau rov qab tsis muaj ntxov tshaj 4-6 teev tom qab lub yav dhau los lo lus uas peb "Asparkam" kev npaj. Analogs ntawm cov tshuaj (e.g., "Panangin") yog muab tib yam. "Panangin" zoo li "Asparkam", muaj ib tug qhia tau cawv rau cov metabolism ntawm myocardiocytes. Yog li ntawd, qhov no analogue "Asparkama" nyob rau hauv Lavxias teb sab yog dav siv nyob rau hauv Cardiology tsev kho mob.

phiv

Nyob rau hauv cov ntaub ntawv uas tau txais ib ntsiav tshuaj daim ntawv tej zaum yuav tshwm sim mob ntawm tus mob huam, uas yog manifested los ntawm kev mob thiab hlawv epigastric, xeev siab, ntuav. Mob thawj coj tej zaum yuav ua rau ulcers ntawm lub mucosa.

Txij li thaum cov tshuaj muaj ib tug predominant cawv rau cov hlab plawv system, nyob rau nws ib feem tej zaum yuav ua rau arrhythmias, conduction ua cuam tshuam, atrioventricular thaiv, tej ntshav siab.

Lub paj hlwb sau ntawv qhov tshwm sim ntawm paresthesia, tingling, laim.

Vim lub high school lub ntsiab lus ntawm magnesium ions thiab lawv nkag mus rau hauv lub hauv paus poob siab system yuav ua pa nyuaj siab muaj nuj nqi. heev feem ntau kuj cim cov kev taw qhia ntawm cov nov ntawm nqaij tawv ntawm tshav kub "Asparkam" tshuaj. Analogs ntawm cov tshuaj muaj zoo xws li cov tsos mob ntawm tus phiv tshua thiab lub zaus ntawm lawv tshwm sim. Nyob rau hauv view ntawm no, nco ntsoov nug rau tus neeg mob lub ua ntej txais ntawm cov tshuaj.

Tshwj xeeb cov lus qhia rau kev siv "Asparkam" tshuaj

Analogs rau cov me nyuam yog lug siv nyob rau hauv xyuas cov neeg mob, txawm hais tias muaj yog tam sim no tsis txaus cov ntaub ntawv nyob rau kev siv ntawm "Asparkama" nyob rau hauv cov me nyuam. Dua li no, cov tshuaj twb tau muab siv ntse rau cov kev kho mob ntawm cov hlab plawv tus kab mob nyob rau hauv Pediatrics.

Yog hais tias ntev-lub sij hawm kev kho mob "Asparkama" pom zoo ceev faj xyuas ntawm electrolytes nyob rau hauv cov ntshav ntshav, saib xyuas electrocardiographic tsis. Tsis tas li ntawd nrog huab ceev faj cov tshuaj no yog siv nyob rau hauv cov neeg mob uas txhawb poov tshuaj ntau nyob rau hauv cov ntshav ntshav.

"Asparkam": counterparts

Ntawm cov tam sim no cov kws ua lag luam generic "Asparkam" cov tshuaj yog muab "Panangin". Nrog high efficiency, active analog "Asparkama" yog dav siv nyob rau hauv Russia raws li nws muaj tus zoo tib yam qauv thiab feem zoo xws li cov indications. Thiab Cardiology xyaum piv txwv. Yog li, "Panangin" - analogous mus rau "Asparkama" nrog rau cov tib pes tsawg leeg.

Cov lwm yam tshuaj muaj zoo xws li cov nyhuv yuav tsum tau muab sau tseg, "Inosine" "Riboxinum" "Meksaritm" "Propanorm" "Ritmokard".